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The map label for this gene is aroE [H]

Identifier: 186477370

GI number: 186477370

Start: 2960705

End: 2961577

Strand: Reverse

Name: aroE [H]

Synonym: Bphy_2622

Alternate gene names: 186477370

Gene position: 2961577-2960705 (Counterclockwise)

Preceding gene: 186477371

Following gene: 186477369

Centisome position: 85.12

GC content: 68.73

Gene sequence:

>873_bases
ATGAGCTCGAATCAAAACACGCCGCGCGACAAATATGCGGTGATCGGCAATCCGATCGCCCACAGCAAGTCGCCCTTGAT
TCACGCGCAGTTTGCCGAGCAAACGGGGCAGCCCGTCGAATATGGCCGGCTGCTGGCACCCGTCGACCAGTTCGTCGCGC
ACGTGCGCGCTTTCATCGACGAAGGCGGCCGCGGCATGAACGTGACCGTGCCGTTCAAGCTCGACGCGCACGCGTTCGCG
ACCGTGCTGTCGCCGCGCGCGGCAGCGGCGGGCGCCGTCAATACGCTGCGCTTCGAAAAGGACGGCGGCGTGTATGGCGA
CAACACGGACGGCTTCGGCCTCGTGCGCGATATCGAAGTGAACCTCGGTGTGCCGCTTGCGGGCGCGCGCGTGCTGCTGC
TGGGCGCGGGCGGCGCGGCACGCGGCGTCGTGCTGCCGATGCTCGAACGCAACCCGCACTCGCTGACCATCGTGAACCGC
ACCGCGTCGAAGGCCCACGAGCTCGTCGCACAATTCGCGAATGGGGCCAGCGCTGCCGCCTGCCGTCTCACAGGCGGCAG
CGCGCAGGCGATCGAAGCGGGCGCGTACGACGTGATCGTCAACGCCACGGCGAGCAGCCTCGATGCGTCGCTGCCCGAGT
GCGATGACGGCGCGTTCGGCACGGGCACGCTCGCGTACGACATGATGTATGGGGCACAGCCGACCGTTTTCATGCAGCAC
GCCAGCAGGCTCGGCGCGCGCGCGGCGGATGGACTCGGCATGCTGGTGGAGCAGGCGGCAGAGTCGTTCTTCGTCTGGCG
CGGCGTGCGTCCCGACGGCGCACCCGTGCTGGCGGCGCTGCGCGAGATGCTGCGCGCACCGCAAAGCGCCTGA

Upstream 100 bases:

>100_bases
CCGACACGGGCGCGTCGGCGGGCGAGCCGTCGGCCGACGGCGACACGCCGGCCTCCGCCAATGACAACGACTCGACGCAG
CACGCGACGGAGCAGGGTCA

Downstream 100 bases:

>100_bases
CGGCGCACGCTCCGTCCGTTAGCCGACTTGACGACATCACAGCGACGACATGGCGACGACGATGACCAAAGGAAGGCGTG
CAAAGGGCCAGGCGGTGAGC

Product: shikimate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 290; Mature: 289

Protein sequence:

>290_residues
MSSNQNTPRDKYAVIGNPIAHSKSPLIHAQFAEQTGQPVEYGRLLAPVDQFVAHVRAFIDEGGRGMNVTVPFKLDAHAFA
TVLSPRAAAAGAVNTLRFEKDGGVYGDNTDGFGLVRDIEVNLGVPLAGARVLLLGAGGAARGVVLPMLERNPHSLTIVNR
TASKAHELVAQFANGASAAACRLTGGSAQAIEAGAYDVIVNATASSLDASLPECDDGAFGTGTLAYDMMYGAQPTVFMQH
ASRLGARAADGLGMLVEQAAESFFVWRGVRPDGAPVLAALREMLRAPQSA

Sequences:

>Translated_290_residues
MSSNQNTPRDKYAVIGNPIAHSKSPLIHAQFAEQTGQPVEYGRLLAPVDQFVAHVRAFIDEGGRGMNVTVPFKLDAHAFA
TVLSPRAAAAGAVNTLRFEKDGGVYGDNTDGFGLVRDIEVNLGVPLAGARVLLLGAGGAARGVVLPMLERNPHSLTIVNR
TASKAHELVAQFANGASAAACRLTGGSAQAIEAGAYDVIVNATASSLDASLPECDDGAFGTGTLAYDMMYGAQPTVFMQH
ASRLGARAADGLGMLVEQAAESFFVWRGVRPDGAPVLAALREMLRAPQSA
>Mature_289_residues
SSNQNTPRDKYAVIGNPIAHSKSPLIHAQFAEQTGQPVEYGRLLAPVDQFVAHVRAFIDEGGRGMNVTVPFKLDAHAFAT
VLSPRAAAAGAVNTLRFEKDGGVYGDNTDGFGLVRDIEVNLGVPLAGARVLLLGAGGAARGVVLPMLERNPHSLTIVNRT
ASKAHELVAQFANGASAAACRLTGGSAQAIEAGAYDVIVNATASSLDASLPECDDGAFGTGTLAYDMMYGAQPTVFMQHA
SRLGARAADGLGMLVEQAAESFFVWRGVRPDGAPVLAALREMLRAPQSA

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1789675, Length=278, Percent_Identity=48.2014388489209, Blast_Score=238, Evalue=3e-64,
Organism=Escherichia coli, GI1787983, Length=269, Percent_Identity=29.7397769516729, Blast_Score=93, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6320332, Length=164, Percent_Identity=32.3170731707317, Blast_Score=80, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 30213; Mature: 30081

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSNQNTPRDKYAVIGNPIAHSKSPLIHAQFAEQTGQPVEYGRLLAPVDQFVAHVRAFID
CCCCCCCCCCCEEEECCCCCCCCCCEEEEEHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
EGGRGMNVTVPFKLDAHAFATVLSPRAAAAGAVNTLRFEKDGGVYGDNTDGFGLVRDIEV
CCCCCCEEEEEEEECHHHHHHHHCCHHHHCCCCEEEEEECCCCCCCCCCCCCEEEEEEEE
NLGVPLAGARVLLLGAGGAARGVVLPMLERNPHSLTIVNRTASKAHELVAQFANGASAAA
ECCCCCCCCEEEEEECCCCCCCEEEEEECCCCCEEEEEECCHHHHHHHHHHHHCCCCCEE
CRLTGGSAQAIEAGAYDVIVNATASSLDASLPECDDGAFGTGTLAYDMMYGAQPTVFMQH
EEECCCCCCEEECCCEEEEEECCHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHH
ASRLGARAADGLGMLVEQAAESFFVWRGVRPDGAPVLAALREMLRAPQSA
HHHHCCHHCCHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SSNQNTPRDKYAVIGNPIAHSKSPLIHAQFAEQTGQPVEYGRLLAPVDQFVAHVRAFID
CCCCCCCCCCEEEECCCCCCCCCCEEEEEHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
EGGRGMNVTVPFKLDAHAFATVLSPRAAAAGAVNTLRFEKDGGVYGDNTDGFGLVRDIEV
CCCCCCEEEEEEEECHHHHHHHHCCHHHHCCCCEEEEEECCCCCCCCCCCCCEEEEEEEE
NLGVPLAGARVLLLGAGGAARGVVLPMLERNPHSLTIVNRTASKAHELVAQFANGASAAA
ECCCCCCCCEEEEEECCCCCCCEEEEEECCCCCEEEEEECCHHHHHHHHHHHHCCCCCEE
CRLTGGSAQAIEAGAYDVIVNATASSLDASLPECDDGAFGTGTLAYDMMYGAQPTVFMQH
EEECCCCCCEEECCCEEEEEECCHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHH
ASRLGARAADGLGMLVEQAAESFFVWRGVRPDGAPVLAALREMLRAPQSA
HHHHCCHHCCHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA