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The map label for this gene is erpA1 [H]

Identifier: 186477310

GI number: 186477310

Start: 2883593

End: 2883958

Strand: Reverse

Name: erpA1 [H]

Synonym: Bphy_2562

Alternate gene names: 186477310

Gene position: 2883958-2883593 (Counterclockwise)

Preceding gene: 186477311

Following gene: 186477308

Centisome position: 82.89

GC content: 56.28

Gene sequence:

>366_bases
ATGGACGCAGTGACCGACACCCCCGTGACCGAGATGCCGGCACCGTTCGTCTTTACTGACGCAGCGGCTGACAAGGTCAA
AGAACTGATCGAAGAAGAAGGCAACCCGGAGCTCAAGCTGCGCGTTTTCGTGCAAGGTGGCGGCTGCTCCGGCTTTCAAT
ATGGTTTCACCTTCGACGAAGCAATCAACGAAGACGACACTGTGATGAACAAGAGCGGCGTCCAGCTGCTGATCGACTCG
ATGAGCTACCAGTATCTGGTGGGCGCGGAGATCGACTACAAGGACGACATCAACGGTGCTCAGTTCGTGATCAAGAACCC
GAACGCCACGACCACTTGCGGTTGCGGTTCGTCGTTTTCGGTGTGA

Upstream 100 bases:

>100_bases
TTCAGCCGCGCCGCATAAGAGCCTATTGATTTCATGGGCATCGGCACGATATCGGGAAGAGCAATACAATAGCGACTAGA
AGCTATTTTGGAGAGTTCGC

Downstream 100 bases:

>100_bases
TCGCACCTTACTTCGCGGTTTACGCCACGTCAGTGGCGGCAAAACGGGGCTTCGGCCCCGTTTTTTATTTGTGCGCGTCA
ACGCGGGTAAATCGCGCCGA

Product: iron-sulfur cluster insertion protein ErpA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 121; Mature: 121

Protein sequence:

>121_residues
MDAVTDTPVTEMPAPFVFTDAAADKVKELIEEEGNPELKLRVFVQGGGCSGFQYGFTFDEAINEDDTVMNKSGVQLLIDS
MSYQYLVGAEIDYKDDINGAQFVIKNPNATTTCGCGSSFSV

Sequences:

>Translated_121_residues
MDAVTDTPVTEMPAPFVFTDAAADKVKELIEEEGNPELKLRVFVQGGGCSGFQYGFTFDEAINEDDTVMNKSGVQLLIDS
MSYQYLVGAEIDYKDDINGAQFVIKNPNATTTCGCGSSFSV
>Mature_121_residues
MDAVTDTPVTEMPAPFVFTDAAADKVKELIEEEGNPELKLRVFVQGGGCSGFQYGFTFDEAINEDDTVMNKSGVQLLIDS
MSYQYLVGAEIDYKDDINGAQFVIKNPNATTTCGCGSSFSV

Specific function: Required for insertion of 4Fe-4S clusters (Potential) [H]

COG id: COG0316

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesB/iscA family [H]

Homologues:

Organism=Homo sapiens, GI160420328, Length=105, Percent_Identity=40.9523809523809, Blast_Score=86, Evalue=5e-18,
Organism=Homo sapiens, GI52426768, Length=122, Percent_Identity=31.1475409836066, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1786351, Length=111, Percent_Identity=59.4594594594595, Blast_Score=150, Evalue=2e-38,
Organism=Escherichia coli, GI1788877, Length=104, Percent_Identity=33.6538461538462, Blast_Score=65, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71998452, Length=105, Percent_Identity=40, Blast_Score=82, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI25146411, Length=114, Percent_Identity=29.8245614035088, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI193209025, Length=112, Percent_Identity=30.3571428571429, Blast_Score=70, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6323001, Length=97, Percent_Identity=40.2061855670103, Blast_Score=76, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24649697, Length=83, Percent_Identity=46.9879518072289, Blast_Score=83, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24642263, Length=120, Percent_Identity=31.6666666666667, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000361
- InterPro:   IPR016092
- InterPro:   IPR017870
- InterPro:   IPR023063 [H]

Pfam domain/function: PF01521 Fe-S_biosyn [H]

EC number: NA

Molecular weight: Translated: 13082; Mature: 13082

Theoretical pI: Translated: 3.76; Mature: 3.76

Prosite motif: PS01152 HESB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAVTDTPVTEMPAPFVFTDAAADKVKELIEEEGNPELKLRVFVQGGGCSGFQYGFTFDE
CCCCCCCCCCCCCCCEEEECHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCEEHHH
AINEDDTVMNKSGVQLLIDSMSYQYLVGAEIDYKDDINGAQFVIKNPNATTTCGCGSSFS
HCCCCCCEECCCCEEEEEECCCCEEEECCCCCCCCCCCCEEEEEECCCCCEEECCCCCCC
V
C
>Mature Secondary Structure
MDAVTDTPVTEMPAPFVFTDAAADKVKELIEEEGNPELKLRVFVQGGGCSGFQYGFTFDE
CCCCCCCCCCCCCCCEEEECHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCEEHHH
AINEDDTVMNKSGVQLLIDSMSYQYLVGAEIDYKDDINGAQFVIKNPNATTTCGCGSSFS
HCCCCCCEECCCCEEEEEECCCCEEEECCCCCCCCCCCCEEEEEECCCCCEEECCCCCCC
V
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA