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The map label for this gene is ompR [H]

Identifier: 186477155

GI number: 186477155

Start: 2704652

End: 2705419

Strand: Reverse

Name: ompR [H]

Synonym: Bphy_2404

Alternate gene names: 186477155

Gene position: 2705419-2704652 (Counterclockwise)

Preceding gene: 186477156

Following gene: 186477154

Centisome position: 77.76

GC content: 61.85

Gene sequence:

>768_bases
ATGAAGCTACACTGTTGGAGTATCGCCAATCGCATGAGCGACGAAGGAGTCTTCATGGACCGACCCGCCCGCATCATCGT
GCTCGACGACGAAGCGGAACTCCGCAACATGCTGCAGCGCTTTCTGAGCGGACATGGCTTCGAAGTGCGCGCCGTCGAGA
ACAGCAAGCGGCTCGAGCGCTATCTGCAGCGCGAGCCGTACGATCTCCTCGTGCTCGATCTGATGATCGGCGACGAAGAC
GGCCTGCAGATCTGCGCGAAACTAAGGGCGGAAGGGCACACGCTGCCCATTCTGATGCTCACCGCGAAGGGCGATCCGCT
TGATCGCGTGATCGGCCTCGAAACGGGTGCTGACGACTACCTGGCCAAGCCCTTCCTGCCGCGCGAACTCGTAGCGCGCA
TCAATGCGCTGCTGCGCCGCCAGAAAATCGCATCGAACGATCCGACCGTCACTACGCAAACGCTGCGTTTCGGCGACTTC
CGGCTCGATGTCGGCAAGCAGTGTCTGTACCGGCAGGACGATCCGCTCGAATTGCACTCGGCGCAGATGTTGCTGCTCAC
CGCGCTCGCAGCGTCGCCGAATCGTGCCGTGAGCCGCGACAATCTGATTGCGCGCGCGCGAGGCCGCGATCACGATGCGC
TCGATCGCAGCATCGACGTTCAGATTCTGCGGCTGCGGCAAGCGATCGAACACGATCCGTCGAAGCCGCGTTTCATCAAG
ACCGTGTGGGGCGTCGGCTATATGCTCGTCGCCGACGTCGAAGCATGA

Upstream 100 bases:

>100_bases
GCGAAATCGACACGCAGAAGCAGGGCTATGTGACGCTCGCCCAGATCGAGCAGTTCATGGCGCAGCGAACGGGTTCGCAT
TGACATAAAAACGGGTCGGC

Downstream 100 bases:

>100_bases
GCGCGCGCGCGCTGCGGTATCTGTTGCCGCGCAGTGTGCTCGGGCGCAACATCGCGCTGCTGATCGTTCTGGTGGCGCTT
AGCCAGGTCTGTGCATTGAG

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MKLHCWSIANRMSDEGVFMDRPARIIVLDDEAELRNMLQRFLSGHGFEVRAVENSKRLERYLQREPYDLLVLDLMIGDED
GLQICAKLRAEGHTLPILMLTAKGDPLDRVIGLETGADDYLAKPFLPRELVARINALLRRQKIASNDPTVTTQTLRFGDF
RLDVGKQCLYRQDDPLELHSAQMLLLTALAASPNRAVSRDNLIARARGRDHDALDRSIDVQILRLRQAIEHDPSKPRFIK
TVWGVGYMLVADVEA

Sequences:

>Translated_255_residues
MKLHCWSIANRMSDEGVFMDRPARIIVLDDEAELRNMLQRFLSGHGFEVRAVENSKRLERYLQREPYDLLVLDLMIGDED
GLQICAKLRAEGHTLPILMLTAKGDPLDRVIGLETGADDYLAKPFLPRELVARINALLRRQKIASNDPTVTTQTLRFGDF
RLDVGKQCLYRQDDPLELHSAQMLLLTALAASPNRAVSRDNLIARARGRDHDALDRSIDVQILRLRQAIEHDPSKPRFIK
TVWGVGYMLVADVEA
>Mature_255_residues
MKLHCWSIANRMSDEGVFMDRPARIIVLDDEAELRNMLQRFLSGHGFEVRAVENSKRLERYLQREPYDLLVLDLMIGDED
GLQICAKLRAEGHTLPILMLTAKGDPLDRVIGLETGADDYLAKPFLPRELVARINALLRRQKIASNDPTVTTQTLRFGDF
RLDVGKQCLYRQDDPLELHSAQMLLLTALAASPNRAVSRDNLIARARGRDHDALDRSIDVQILRLRQAIEHDPSKPRFIK
TVWGVGYMLVADVEA

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=237, Percent_Identity=48.9451476793249, Blast_Score=246, Evalue=1e-66,
Organism=Escherichia coli, GI1786599, Length=229, Percent_Identity=37.5545851528384, Blast_Score=139, Evalue=1e-34,
Organism=Escherichia coli, GI1787229, Length=234, Percent_Identity=34.1880341880342, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1788394, Length=229, Percent_Identity=34.061135371179, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1790860, Length=229, Percent_Identity=35.8078602620087, Blast_Score=124, Evalue=5e-30,
Organism=Escherichia coli, GI1790863, Length=236, Percent_Identity=29.2372881355932, Blast_Score=120, Evalue=8e-29,
Organism=Escherichia coli, GI1790552, Length=231, Percent_Identity=34.1991341991342, Blast_Score=117, Evalue=7e-28,
Organism=Escherichia coli, GI1786784, Length=226, Percent_Identity=33.1858407079646, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI2367329, Length=232, Percent_Identity=37.0689655172414, Blast_Score=114, Evalue=4e-27,
Organism=Escherichia coli, GI1789402, Length=227, Percent_Identity=33.920704845815, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1786911, Length=225, Percent_Identity=30.6666666666667, Blast_Score=108, Evalue=2e-25,
Organism=Escherichia coli, GI1787375, Length=226, Percent_Identity=31.4159292035398, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI87082012, Length=228, Percent_Identity=31.140350877193, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI145693140, Length=231, Percent_Identity=32.034632034632, Blast_Score=106, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 28980; Mature: 28980

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLHCWSIANRMSDEGVFMDRPARIIVLDDEAELRNMLQRFLSGHGFEVRAVENSKRLER
CEEEHHHHHHHCCCCCEEECCCEEEEEECCHHHHHHHHHHHHCCCCEEEEEECCHHHHHH
YLQREPYDLLVLDLMIGDEDGLQICAKLRAEGHTLPILMLTAKGDPLDRVIGLETGADDY
HHHCCCCCEEEEEEEECCCHHHHHHHHHHCCCCEEEEEEEEECCCCHHHEEECCCCCCHH
LAKPFLPRELVARINALLRRQKIASNDPTVTTQTLRFGDFRLDVGKQCLYRQDDPLELHS
HCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCEEECCCHHHHCCCCCCCHHHH
AQMLLLTALAASPNRAVSRDNLIARARGRDHDALDRSIDVQILRLRQAIEHDPSKPRFIK
HHHHHHHHHHCCCCCCCCCCCEEEECCCCCHHHHCCHHHHHHHHHHHHHHCCCCCCHHHH
TVWGVGYMLVADVEA
HHHCCCEEEEEECCC
>Mature Secondary Structure
MKLHCWSIANRMSDEGVFMDRPARIIVLDDEAELRNMLQRFLSGHGFEVRAVENSKRLER
CEEEHHHHHHHCCCCCEEECCCEEEEEECCHHHHHHHHHHHHCCCCEEEEEECCHHHHHH
YLQREPYDLLVLDLMIGDEDGLQICAKLRAEGHTLPILMLTAKGDPLDRVIGLETGADDY
HHHCCCCCEEEEEEEECCCHHHHHHHHHHCCCCEEEEEEEEECCCCHHHEEECCCCCCHH
LAKPFLPRELVARINALLRRQKIASNDPTVTTQTLRFGDFRLDVGKQCLYRQDDPLELHS
HCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCEEECCCHHHHCCCCCCCHHHH
AQMLLLTALAASPNRAVSRDNLIARARGRDHDALDRSIDVQILRLRQAIEHDPSKPRFIK
HHHHHHHHHHCCCCCCCCCCCEEEECCCCCHHHHCCHHHHHHHHHHHHHHCCCCCCHHHH
TVWGVGYMLVADVEA
HHHCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]