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The map label for this gene is gbpR [H]

Identifier: 186477145

GI number: 186477145

Start: 2688932

End: 2689876

Strand: Direct

Name: gbpR [H]

Synonym: Bphy_2394

Alternate gene names: 186477145

Gene position: 2688932-2689876 (Clockwise)

Preceding gene: 186477143

Following gene: 186477149

Centisome position: 77.29

GC content: 58.94

Gene sequence:

>945_bases
ATGTCGCAAGATCCCAGCCTCTCCATCACGCAAGTGCTGACCAAGCTGCGTTTCAGACATCTCCAGTTGCTTGAACTGCT
CGGTCGTACCCGCAACCTTCGTATCGCGGCTGAGCAGATGCACATCACTCAGCCGGCCGCCACGAAGATCCTGAGCGATC
TGGAGGCGATGTTAGGCGCGCCGCTGTTCGAACGGCTGCCGCGCGAAATGCGGCCGACGGATCTCGGTACGCTGTCGCTG
CGCTACGCCAGCACGACACTGTCCAATCTGGGCAAGTTTTCGAGCGAGTTCGCGACATTGAAAGATGGCGGCTATGGTCA
TCTCACGGTCGGCTTCATTCCGGCTTCCGCCGCGCAACTCGTCACCGCGGCTATCAAGGAGATCCAGCGCCGGCGCCCGA
GACTCATCATCAAACTGGTCGAGCAAAGCAGTGATCAGCTCGCGACGTGGCTTGAGGCAAGGCAGCTCGATGTGATGATT
GGGCGCCCGACCGAGCCACGACACGAGGCGCTTTTCGATGTGATCGATTTATTGGCGGAGCCGGCGCTTGCGGTCGTCGG
GAAGCATCATCCGTTGCTGAAGCAACGACGCATAGAGATCGCCGACCTGGGCGAGTGGCCGTGGATCTTGTATCCGCAAG
GCACCGCCATGCGGCAACTGTTCGAAGAAACGTTCGCGGCGGCTGGCATGGTTGCGCCGATGGGCATCGTGGAAACGCCA
TCGATTTTTACGACGTTAGAGTTGCTGCAGGCAACCGACATGATGTCCCTTCAACCGAGAGCGGCGATGGACAAGTACGT
CACGCATGGCCTTCTAGGCTATCTGGACGTGCCGATACGGCGGACATTGTCGAACTACAGTGTCATTACACGGAAAGACG
AAGCCGCTTCGCAGGCGATGAACGAATTCGTTGCCATCCTCCAGGCAATCGCCGCGCAATACTAG

Upstream 100 bases:

>100_bases
CGACGCGCTTTGAATTGTCGTTCGAGCTTGCGATAACCGTCCAATTGCGAATTGAGTAAAATCAATTCCGTCTGGTTATA
AATCGGCTCGTGTTTACCCT

Downstream 100 bases:

>100_bases
GTTAGTCAACGTGGCCGTTGTGAGAGCACGATTCCCGGTTACGCAGGCAGGGGCAGCGTCGGCATGCTCTTGATGTGCTT
GCTGCCGAAGTTGGCGATTG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Galactose-binding protein regulator; GBP regulator [H]

Number of amino acids: Translated: 314; Mature: 313

Protein sequence:

>314_residues
MSQDPSLSITQVLTKLRFRHLQLLELLGRTRNLRIAAEQMHITQPAATKILSDLEAMLGAPLFERLPREMRPTDLGTLSL
RYASTTLSNLGKFSSEFATLKDGGYGHLTVGFIPASAAQLVTAAIKEIQRRRPRLIIKLVEQSSDQLATWLEARQLDVMI
GRPTEPRHEALFDVIDLLAEPALAVVGKHHPLLKQRRIEIADLGEWPWILYPQGTAMRQLFEETFAAAGMVAPMGIVETP
SIFTTLELLQATDMMSLQPRAAMDKYVTHGLLGYLDVPIRRTLSNYSVITRKDEAASQAMNEFVAILQAIAAQY

Sequences:

>Translated_314_residues
MSQDPSLSITQVLTKLRFRHLQLLELLGRTRNLRIAAEQMHITQPAATKILSDLEAMLGAPLFERLPREMRPTDLGTLSL
RYASTTLSNLGKFSSEFATLKDGGYGHLTVGFIPASAAQLVTAAIKEIQRRRPRLIIKLVEQSSDQLATWLEARQLDVMI
GRPTEPRHEALFDVIDLLAEPALAVVGKHHPLLKQRRIEIADLGEWPWILYPQGTAMRQLFEETFAAAGMVAPMGIVETP
SIFTTLELLQATDMMSLQPRAAMDKYVTHGLLGYLDVPIRRTLSNYSVITRKDEAASQAMNEFVAILQAIAAQY
>Mature_313_residues
SQDPSLSITQVLTKLRFRHLQLLELLGRTRNLRIAAEQMHITQPAATKILSDLEAMLGAPLFERLPREMRPTDLGTLSLR
YASTTLSNLGKFSSEFATLKDGGYGHLTVGFIPASAAQLVTAAIKEIQRRRPRLIIKLVEQSSDQLATWLEARQLDVMIG
RPTEPRHEALFDVIDLLAEPALAVVGKHHPLLKQRRIEIADLGEWPWILYPQGTAMRQLFEETFAAAGMVAPMGIVETPS
IFTTLELLQATDMMSLQPRAAMDKYVTHGLLGYLDVPIRRTLSNYSVITRKDEAASQAMNEFVAILQAIAAQY

Specific function: Does not seem to be required for sbpA expression [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI157672245, Length=243, Percent_Identity=28.8065843621399, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI87081904, Length=286, Percent_Identity=26.2237762237762, Blast_Score=98, Evalue=8e-22,
Organism=Escherichia coli, GI1788887, Length=190, Percent_Identity=27.8947368421053, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI145693105, Length=287, Percent_Identity=25.7839721254355, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1789204, Length=262, Percent_Identity=24.4274809160305, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1790399, Length=203, Percent_Identity=27.5862068965517, Blast_Score=68, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35041; Mature: 34910

Theoretical pI: Translated: 7.95; Mature: 7.95

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQDPSLSITQVLTKLRFRHLQLLELLGRTRNLRIAAEQMHITQPAATKILSDLEAMLGA
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHCCCHHHHHHHHHHHHHHCC
PLFERLPREMRPTDLGTLSLRYASTTLSNLGKFSSEFATLKDGGYGHLTVGFIPASAAQL
HHHHHCCHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECHHHHHH
VTAAIKEIQRRRPRLIIKLVEQSSDQLATWLEARQLDVMIGRPTEPRHEALFDVIDLLAE
HHHHHHHHHHHCHHHHHHHHHCCHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHC
PALAVVGKHHPLLKQRRIEIADLGEWPWILYPQGTAMRQLFEETFAAAGMVAPMGIVETP
CHHHHHCCCCHHHHHHCCCHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCC
SIFTTLELLQATDMMSLQPRAAMDKYVTHGLLGYLDVPIRRTLSNYSVITRKDEAASQAM
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHH
NEFVAILQAIAAQY
HHHHHHHHHHHHCC
>Mature Secondary Structure 
SQDPSLSITQVLTKLRFRHLQLLELLGRTRNLRIAAEQMHITQPAATKILSDLEAMLGA
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHCCCHHHHHHHHHHHHHHCC
PLFERLPREMRPTDLGTLSLRYASTTLSNLGKFSSEFATLKDGGYGHLTVGFIPASAAQL
HHHHHCCHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECHHHHHH
VTAAIKEIQRRRPRLIIKLVEQSSDQLATWLEARQLDVMIGRPTEPRHEALFDVIDLLAE
HHHHHHHHHHHCHHHHHHHHHCCHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHC
PALAVVGKHHPLLKQRRIEIADLGEWPWILYPQGTAMRQLFEETFAAAGMVAPMGIVETP
CHHHHHCCCCHHHHHHCCCHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCC
SIFTTLELLQATDMMSLQPRAAMDKYVTHGLLGYLDVPIRRTLSNYSVITRKDEAASQAM
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHH
NEFVAILQAIAAQY
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10361275 [H]