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The map label for this gene is oxyR [H]

Identifier: 186477116

GI number: 186477116

Start: 2657415

End: 2658347

Strand: Direct

Name: oxyR [H]

Synonym: Bphy_2365

Alternate gene names: 186477116

Gene position: 2657415-2658347 (Clockwise)

Preceding gene: 186477112

Following gene: 186477121

Centisome position: 76.38

GC content: 64.09

Gene sequence:

>933_bases
ATGAATACGCGATTTCTCGAGACTTTCGTCACGCTGGCCAAGCTGCGCAGCTTCCGCACCACGGCGACCGCGTTGCACGC
CACGCCCGCTGCGATCTCGCAACGGCTGAAGGCGCTGGAAGACGAATTGCAAACCACGCTCGTCGATCGTGAGAGCCGCG
ACTTCCGCCTCACGGCGAACGGCGAGTATCTGCTTGGCTATGCGAAGGCCGTGGTGGAGGCGACGCGTCAGTTGCAGGCC
GCGGCCTCACACGAAGGGGCGATGCGCGGCAAGCTGCGGCTCGGCGTGATCGAGACGGTCGTGCATAGTTGGCTCGCCGA
TTACATGCGACGCCTCGCGGACGACTTTCCGCAACTCGAAGTCGAACTGGCTGTGGACGTGAGCGTGGTGTTGCAGCGGC
GGCTGATGGCGGGCGAGCTCGATCTGATAGTTCGCGTGGAAGGCAGCGACGAGGAATCCGTGGTGTGCGATGCGCTTGCC
AACTATCCGGTGCACTGGATAGCACGCGCGGGTCTACTGCCGCTTTCGCGCAGCGGGCTCGCCAAGCGTGTGTTGCGTCA
TCCGATCCTGACGTTCGGGCGCGGAACTGCGCCGCATCGAGCGCTGGAGGACATCGTCGGCAAGCTGGCGCTCGCGAATG
GCGTACCGCTCGCGGACACGCGCATTACGGGCTCGCCGTCGATTTCGGTAATCGTGCAACTCGTGCGTGATGGATTCGGC
GTGGCGGCGATTCCGCGTCTTTTCGTCGACGATCTGATCGCGCGCGGCGAGGTGGTGGAGTTACCTTTGCAGCCTTCGCC
ACCTTCCATCGTGGTGTCGATGTCGCGACGCTCGGACGCGCCACTGTTCGTGCACGGCGCAGCGAACGCGGCGCGTACGG
CATGTCATGAATATTGCGCAGCCGGGGATCCGCGCCTGATTGAGCGCCTGTAA

Upstream 100 bases:

>100_bases
CGTCGAATGAATAGAATTTCTTAACGCATTCGCGGGTTTTCCCGGATCGCGTTGAGATTTTTGGAACAGTTCTTGTTGTT
GCCCGAGCGGCCTTCGGCTT

Downstream 100 bases:

>100_bases
AGCCGGGGCACGCGCACGTCTGTTGAGGAAATTGACAGTGTGAACATGGGGACCGGGGAACGGTGCGTCACGCGATGGCG
TCCATCAAGCGGTACCACGC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Morphology and auto-aggregation control protein [H]

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MNTRFLETFVTLAKLRSFRTTATALHATPAAISQRLKALEDELQTTLVDRESRDFRLTANGEYLLGYAKAVVEATRQLQA
AASHEGAMRGKLRLGVIETVVHSWLADYMRRLADDFPQLEVELAVDVSVVLQRRLMAGELDLIVRVEGSDEESVVCDALA
NYPVHWIARAGLLPLSRSGLAKRVLRHPILTFGRGTAPHRALEDIVGKLALANGVPLADTRITGSPSISVIVQLVRDGFG
VAAIPRLFVDDLIARGEVVELPLQPSPPSIVVSMSRRSDAPLFVHGAANAARTACHEYCAAGDPRLIERL

Sequences:

>Translated_310_residues
MNTRFLETFVTLAKLRSFRTTATALHATPAAISQRLKALEDELQTTLVDRESRDFRLTANGEYLLGYAKAVVEATRQLQA
AASHEGAMRGKLRLGVIETVVHSWLADYMRRLADDFPQLEVELAVDVSVVLQRRLMAGELDLIVRVEGSDEESVVCDALA
NYPVHWIARAGLLPLSRSGLAKRVLRHPILTFGRGTAPHRALEDIVGKLALANGVPLADTRITGSPSISVIVQLVRDGFG
VAAIPRLFVDDLIARGEVVELPLQPSPPSIVVSMSRRSDAPLFVHGAANAARTACHEYCAAGDPRLIERL
>Mature_310_residues
MNTRFLETFVTLAKLRSFRTTATALHATPAAISQRLKALEDELQTTLVDRESRDFRLTANGEYLLGYAKAVVEATRQLQA
AASHEGAMRGKLRLGVIETVVHSWLADYMRRLADDFPQLEVELAVDVSVVLQRRLMAGELDLIVRVEGSDEESVVCDALA
NYPVHWIARAGLLPLSRSGLAKRVLRHPILTFGRGTAPHRALEDIVGKLALANGVPLADTRITGSPSISVIVQLVRDGFG
VAAIPRLFVDDLIARGEVVELPLQPSPPSIVVSMSRRSDAPLFVHGAANAARTACHEYCAAGDPRLIERL

Specific function: Hydrogen peroxide sensor. Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS (a regulatory RNA), dps, fur and grxA. OxyR expression is negatively autoregulated by binding to a 43 bp region upstre

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=290, Percent_Identity=27.9310344827586, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1789639, Length=291, Percent_Identity=25.7731958762887, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI48994962, Length=152, Percent_Identity=30.9210526315789, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1790208, Length=145, Percent_Identity=28.9655172413793, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788297, Length=161, Percent_Identity=29.8136645962733, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33808; Mature: 33808

Theoretical pI: Translated: 7.67; Mature: 7.67

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTRFLETFVTLAKLRSFRTTATALHATPAAISQRLKALEDELQTTLVDRESRDFRLTAN
CCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEC
GEYLLGYAKAVVEATRQLQAAASHEGAMRGKLRLGVIETVVHSWLADYMRRLADDFPQLE
CCCHHHHHHHHHHHHHHHHHHHHCCCHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
VELAVDVSVVLQRRLMAGELDLIVRVEGSDEESVVCDALANYPVHWIARAGLLPLSRSGL
EEEEHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHCCCHHHHHHCCCCCCCHHHH
AKRVLRHPILTFGRGTAPHRALEDIVGKLALANGVPLADTRITGSPSISVIVQLVRDGFG
HHHHHHCHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCC
VAAIPRLFVDDLIARGEVVELPLQPSPPSIVVSMSRRSDAPLFVHGAANAARTACHEYCA
HHHHHHHHHHHHHCCCCEEEECCCCCCCCEEEEECCCCCCCEEEECCCHHHHHHHHHHHC
AGDPRLIERL
CCCHHHHHCC
>Mature Secondary Structure
MNTRFLETFVTLAKLRSFRTTATALHATPAAISQRLKALEDELQTTLVDRESRDFRLTAN
CCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEC
GEYLLGYAKAVVEATRQLQAAASHEGAMRGKLRLGVIETVVHSWLADYMRRLADDFPQLE
CCCHHHHHHHHHHHHHHHHHHHHCCCHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
VELAVDVSVVLQRRLMAGELDLIVRVEGSDEESVVCDALANYPVHWIARAGLLPLSRSGL
EEEEHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHCCCHHHHHHCCCCCCCHHHH
AKRVLRHPILTFGRGTAPHRALEDIVGKLALANGVPLADTRITGSPSISVIVQLVRDGFG
HHHHHHCHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCC
VAAIPRLFVDDLIARGEVVELPLQPSPPSIVVSMSRRSDAPLFVHGAANAARTACHEYCA
HHHHHHHHHHHHHCCCCEEEECCCCCCCCEEEEECCCCCCCEEEECCCHHHHHHHHHHHC
AGDPRLIERL
CCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]