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The map label for this gene is xanB [H]

Identifier: 186477044

GI number: 186477044

Start: 2572569

End: 2574002

Strand: Direct

Name: xanB [H]

Synonym: Bphy_2293

Alternate gene names: 186477044

Gene position: 2572569-2574002 (Clockwise)

Preceding gene: 186477039

Following gene: 186477045

Centisome position: 73.94

GC content: 61.51

Gene sequence:

>1434_bases
ATGGCGAACCTACCCATCGTGCCCGTCATCCTCGCTGGCGGCTCCGGAACGCGGTTGTGGCCCCTTTCCAGGGCGCTATT
CCCGAAGCAGTTCCTGCCGTTGACGGGCGAACGCACCATGCTGCAGGAAACGCTGAAGCGGCTGGAAGGTATAGAGGGCC
TGTGCAGCCCATTGGTCGTATGTCACGACGACCATCGGTTCATTGTCGCCGAGCAGCTGCGTCAGCACCATTCGCTCGAT
GCCACGATCATTCTCGAGCCCGTTAGCCGCAACACCGCGCCCGCCATCGCCGTCTCGGCGCTCCAGGCGCTGCGCGACGG
CTCGGACCCACTTCTGCTGGTTCTCGCAGCCGACCACGTGATCCGCGATGTGGAGGTGTTCCATCAAGCCGTCGCAGCGG
CCGCCGAGGTGGCCGAAACGGGCGCGATGGCGACGTTCGGCATCAAACCCGTCGCTCCTGAAACGGGCTACGGTTATCTG
CGCGCGGCGCCCGGCGAGCAGGGCCAGGTGATGCGGCTCGCGACGTTCGTCGAAAAGCCCGATCTCGTCACCGCACGAGC
CTACTTGGCGTCCGGCGAGTATTTCTGGAATAGCGGCATGTTCCTGTTTCGCGCGTCAGTGTATCTGAAAGAACTCGAAA
AATTCGCGCCGGACATGGTCGCCGCCTGCCGGGCATCTCTCGACGCCGCCAAGGACGACCTGGACTTCGTGCGGCTCGAC
AAGGAAACTTTCTCCCAGTCGCCGGAAGATTCCGTCGACTACGCCGTCATGGAGAAGACCGACAAGGCGATGATCGTCTC
GCTCGATGCGGGCTGGAGCGATGTCGGCTCGTGGTCGGCGCTGTGGGACGTGGCCGACAAGGACGGCGACGGCAACGTGA
CCAAGGGCGACGTAATCGGCTTCGGCAATCAGAACTGCTTCCTTCAGTCGTCGGGCGGCCGCCTGGTGGCGGCTGTCGGC
CTGGATAACCTGATCGTCGTCGACACAGACGACGCAGTGCTGATAGCCAACAAAAAGGACGTCCAGCACGTCAAGAAAAT
TGTCGAAAAGCTGAAGGCCGAGCAGCGCTCGGAAGCCGTTCAACACCGTCTGGTCTATCGCCCGTGGGGCAGCTACGATT
CGATCGATAAAGGCGCACGCTACCAGGTAAAACGCATCACCGTGAACCCCGGCGCCAAGCTCTCCGTGCAAATGCACCAT
CATAGGGCAGAGCACTGGGTCGTCGTTTCGGGCACCGCACACGTCCAGAACGGCGAGCACGAGACGCTGCTGACCGAGAA
TGAGTCGGTCTATATCCCCGTGGGGAATGTCCACGCGCTGGAAAATCCAGGAAAAATCCCACTTGAATTGATCGAAGTCC
AATCCGGCGCTTATCTCGGCGAAGACGACATCGTCCGCTTCGACGACCGCTACGGCAGACACGAAAGGAAGTAA

Upstream 100 bases:

>100_bases
GCAATTTGTGCCCTCGCCCACGCGCGAGAGCGACGCCGGGCCGGCGTTTCCCACGCTTTATTCAGCGTGATCCAGAATAT
TATTGCTTGAAGGCTTCCTC

Downstream 100 bases:

>100_bases
AGGTCAAGCCCCCGGCGCGCTCGCCGCAACCCGCTCGTCGCCGGTTGCGCGTTCATGTACCATACGCCACTTGGCAGTGC
GACCGGAAGGCAGCATTCCT

Product: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase

Products: NA

Alternate protein names: Mannose-6-phosphate isomerase; Phosphohexomutase; Phosphomannose isomerase; PMI; Mannose-1-phosphate guanylyl transferase; GDP-mannose pyrophosphorylase; GMP; GMPP [H]

Number of amino acids: Translated: 477; Mature: 476

Protein sequence:

>477_residues
MANLPIVPVILAGGSGTRLWPLSRALFPKQFLPLTGERTMLQETLKRLEGIEGLCSPLVVCHDDHRFIVAEQLRQHHSLD
ATIILEPVSRNTAPAIAVSALQALRDGSDPLLLVLAADHVIRDVEVFHQAVAAAAEVAETGAMATFGIKPVAPETGYGYL
RAAPGEQGQVMRLATFVEKPDLVTARAYLASGEYFWNSGMFLFRASVYLKELEKFAPDMVAACRASLDAAKDDLDFVRLD
KETFSQSPEDSVDYAVMEKTDKAMIVSLDAGWSDVGSWSALWDVADKDGDGNVTKGDVIGFGNQNCFLQSSGGRLVAAVG
LDNLIVVDTDDAVLIANKKDVQHVKKIVEKLKAEQRSEAVQHRLVYRPWGSYDSIDKGARYQVKRITVNPGAKLSVQMHH
HRAEHWVVVSGTAHVQNGEHETLLTENESVYIPVGNVHALENPGKIPLELIEVQSGAYLGEDDIVRFDDRYGRHERK

Sequences:

>Translated_477_residues
MANLPIVPVILAGGSGTRLWPLSRALFPKQFLPLTGERTMLQETLKRLEGIEGLCSPLVVCHDDHRFIVAEQLRQHHSLD
ATIILEPVSRNTAPAIAVSALQALRDGSDPLLLVLAADHVIRDVEVFHQAVAAAAEVAETGAMATFGIKPVAPETGYGYL
RAAPGEQGQVMRLATFVEKPDLVTARAYLASGEYFWNSGMFLFRASVYLKELEKFAPDMVAACRASLDAAKDDLDFVRLD
KETFSQSPEDSVDYAVMEKTDKAMIVSLDAGWSDVGSWSALWDVADKDGDGNVTKGDVIGFGNQNCFLQSSGGRLVAAVG
LDNLIVVDTDDAVLIANKKDVQHVKKIVEKLKAEQRSEAVQHRLVYRPWGSYDSIDKGARYQVKRITVNPGAKLSVQMHH
HRAEHWVVVSGTAHVQNGEHETLLTENESVYIPVGNVHALENPGKIPLELIEVQSGAYLGEDDIVRFDDRYGRHERK
>Mature_476_residues
ANLPIVPVILAGGSGTRLWPLSRALFPKQFLPLTGERTMLQETLKRLEGIEGLCSPLVVCHDDHRFIVAEQLRQHHSLDA
TIILEPVSRNTAPAIAVSALQALRDGSDPLLLVLAADHVIRDVEVFHQAVAAAAEVAETGAMATFGIKPVAPETGYGYLR
AAPGEQGQVMRLATFVEKPDLVTARAYLASGEYFWNSGMFLFRASVYLKELEKFAPDMVAACRASLDAAKDDLDFVRLDK
ETFSQSPEDSVDYAVMEKTDKAMIVSLDAGWSDVGSWSALWDVADKDGDGNVTKGDVIGFGNQNCFLQSSGGRLVAAVGL
DNLIVVDTDDAVLIANKKDVQHVKKIVEKLKAEQRSEAVQHRLVYRPWGSYDSIDKGARYQVKRITVNPGAKLSVQMHHH
RAEHWVVVSGTAHVQNGEHETLLTENESVYIPVGNVHALENPGKIPLELIEVQSGAYLGEDDIVRFDDRYGRHERK

Specific function: Involved in xanthan production [H]

COG id: COG0836

COG function: function code M; Mannose-1-phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannose-6-phosphate isomerase type 2 family [H]

Homologues:

Organism=Escherichia coli, GI1788362, Length=480, Percent_Identity=60.8333333333333, Blast_Score=563, Evalue=1e-162,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR006375
- InterPro:   IPR001538
- InterPro:   IPR005835
- InterPro:   IPR014710 [H]

Pfam domain/function: PF01050 MannoseP_isomer; PF00483 NTP_transferase [H]

EC number: =5.3.1.8; =2.7.7.13 [H]

Molecular weight: Translated: 52380; Mature: 52249

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: PS00018 EF_HAND_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANLPIVPVILAGGSGTRLWPLSRALFPKQFLPLTGERTMLQETLKRLEGIEGLCSPLVV
CCCCCEEEEEEECCCCCEEEECHHHHCCHHHCCCCCCHHHHHHHHHHHHCCHHHHCCEEE
CHDDHRFIVAEQLRQHHSLDATIILEPVSRNTAPAIAVSALQALRDGSDPLLLVLAADHV
EECCCCCHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEEECHHH
IRDVEVFHQAVAAAAEVAETGAMATFGIKPVAPETGYGYLRAAPGEQGQVMRLATFVEKP
HHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCEEEECCCCCCCEEEEEHHHCCC
DLVTARAYLASGEYFWNSGMFLFRASVYLKELEKFAPDMVAACRASLDAAKDDLDFVRLD
CCEEEHHHHCCCCEEECCCEEEHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCEEEEC
KETFSQSPEDSVDYAVMEKTDKAMIVSLDAGWSDVGSWSALWDVADKDGDGNVTKGDVIG
HHHHCCCCCCCCCCCEEECCCCEEEEEECCCCCCCCCCHHEEECCCCCCCCCCCCCCEEE
FGNQNCFLQSSGGRLVAAVGLDNLIVVDTDDAVLIANKKDVQHVKKIVEKLKAEQRSEAV
ECCCCEEEECCCCEEEEEECCCCEEEEECCCEEEEECCHHHHHHHHHHHHHHHHHHHHHH
QHRLVYRPWGSYDSIDKGARYQVKRITVNPGAKLSVQMHHHRAEHWVVVSGTAHVQNGEH
HHCEEECCCCCCCCCCCCCCEEEEEEEECCCCEEEEEEECCCCCEEEEEECCEEECCCCC
ETLLTENESVYIPVGNVHALENPGKIPLELIEVQSGAYLGEDDIVRFDDRYGRHERK
CEEEECCCEEEEECCCEEECCCCCCCCEEEEEECCCCEECCCCEEEECCCCCCCCCC
>Mature Secondary Structure 
ANLPIVPVILAGGSGTRLWPLSRALFPKQFLPLTGERTMLQETLKRLEGIEGLCSPLVV
CCCCEEEEEEECCCCCEEEECHHHHCCHHHCCCCCCHHHHHHHHHHHHCCHHHHCCEEE
CHDDHRFIVAEQLRQHHSLDATIILEPVSRNTAPAIAVSALQALRDGSDPLLLVLAADHV
EECCCCCHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEEECHHH
IRDVEVFHQAVAAAAEVAETGAMATFGIKPVAPETGYGYLRAAPGEQGQVMRLATFVEKP
HHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCEEEECCCCCCCEEEEEHHHCCC
DLVTARAYLASGEYFWNSGMFLFRASVYLKELEKFAPDMVAACRASLDAAKDDLDFVRLD
CCEEEHHHHCCCCEEECCCEEEHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCEEEEC
KETFSQSPEDSVDYAVMEKTDKAMIVSLDAGWSDVGSWSALWDVADKDGDGNVTKGDVIG
HHHHCCCCCCCCCCCEEECCCCEEEEEECCCCCCCCCCHHEEECCCCCCCCCCCCCCEEE
FGNQNCFLQSSGGRLVAAVGLDNLIVVDTDDAVLIANKKDVQHVKKIVEKLKAEQRSEAV
ECCCCEEEECCCCEEEEEECCCCEEEEECCCEEEEECCHHHHHHHHHHHHHHHHHHHHHH
QHRLVYRPWGSYDSIDKGARYQVKRITVNPGAKLSVQMHHHRAEHWVVVSGTAHVQNGEH
HHCEEECCCCCCCCCCCCCCEEEEEEEECCCCEEEEEEECCCCCEEEEEECCEEECCCCC
ETLLTENESVYIPVGNVHALENPGKIPLELIEVQSGAYLGEDDIVRFDDRYGRHERK
CEEEECCCEEEEECCCEEECCCCCCCCEEEEEECCCCEECCCCEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1370280; 11589581 [H]