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The map label for this gene is xanB [H]

Identifier: 186477034

GI number: 186477034

Start: 2558502

End: 2560043

Strand: Direct

Name: xanB [H]

Synonym: Bphy_2283

Alternate gene names: 186477034

Gene position: 2558502-2560043 (Clockwise)

Preceding gene: 186477032

Following gene: 186477035

Centisome position: 73.54

GC content: 66.02

Gene sequence:

>1542_bases
ATGAACGTCATTGCAGAAGCAGTCTCGCCGGATGCGCTCACGCACGACACGCAGCTTGCCTGCGTCGTTCAACCTGTCGT
CCTGGCTGGCGGCTCGGGCACGCGCCTGTGGCCACTGTCGCGCGAGCAGTGCCCGAAACAACTGATCGGGCTGACAAGCG
AGGAATCGCTGCTCGAAGCGACGCTGCGCAGAACCTTGGGACTGAGCGCGCCGACACGGGAGCGGCCCGCGCCGCATGCC
ATCAGAACGCAGCCGACGCTCGTCGTCTGCAGCGAGGAGTTGCGCCTGCCCACGAAAGAACGGCTCGACCGCTGCACGAG
CGATTCCCGCGTCGTGCTGGAGCCGGCGCCGCGCAATACCGCCCCCGCCCTGACGGTGGCTGCGCTGGCCGCACGGGCGG
CTGCGCCGGAGGGCGAAGATCCCGTACTCGTCGTGATGCCCGCCGATCATCTGATCGCCGATTCGCAGGCCTTCGTGGCC
ACCCTGCAGCACGCCATCCAGCATGCGCTGCACGATGCGATCGTCACGCTGGGCGTGCCACCCGAGCGTCCCGAAACAGG
CTACGGCTACATCAAGACGGGCGCACCCGCCGACGGCCGCGGGGCGCGGACCATCGAGCGCTTCGTCGAAAAACCCGCAC
AGCAAACGGCCGAACAGTATGTCGCATCGGGTGAGTACTGGTGGAACAGCGGCATTTTCGTGATGCGCGCATCCGTCTGG
CTCGCGGCCATCGAAGCATGCCGGCACGATATCGCTGCCGCGTGCCAGGCGTCGTACGAACAGGCAAAGCTCGACGGCGA
CGGCACGCTGCACATCGACCATGCCGCGTTTGCCGACTGCCCCAGCGATTCAATCGACTACGCGGTGATGGAGCGTATCG
GCGACAACCCGACGCTCACGGGCGTCATCGTGCCGCTCACGGCCGGCTGGTCCGACGTGGGCGCATGGGACGCCGTGTGG
GACGTGAGCGCAAAGGACGATGCAGGCAATGTCGCGCGCGGGCGCGTGCTGCTCGAGGGGTCGAAGGACACCTATGCACA
TTCGGAAGGACGGCTCGTCGCGTGCGTCGGCGTGACGGGTGTGGTGGTGGTCGAGACAGCCGATGCCGTGCTCGTCGCCG
CGAAGGACCGCGTACAGGACGTCAAGGCGATCGTGAACCGGCTGAACGCCGCGAAAGACACGGAAGCGAAGGTACATCGG
AAGGTGGAGCGGCCGTGGGGCTGCTATGACTCCATCGATCGCGGCGAGCGCTTTCAGGTGAAGCGGATCGTCGTGAAACC
GGGCGGCCAGCTATCGCTTCAGATGCATCATCATCGCGCGGAACACTGGATCGTCGTGCGCGGCACCGCGCGCGTCACGC
GCGGCGACGAAACGTTCCTGATCACCGAGAACCAGTCGACGTATATTCCGCTGGGCACGCTGCACCGGCTGGAGAATCCG
GGTAAGACGCCGCTCGAGATCATCGAGGTCCAATCGGGTGGTTATCTCGGCGAGGATGATATCGTGCGCTTCGACGACCG
GTACGGGCGCACGGGAAGCTAG

Upstream 100 bases:

>100_bases
CTTTGTGCCCGGACGCACAGAAATTCTGCGTAACGATTGGTCCAATTGCCAGACGTAACGGCGCCAGGTCATGCCCCCGA
CCGGCGTCTTCGGAGGAAAA

Downstream 100 bases:

>100_bases
CGCCAGGCGGTGCCAGTCCGGCCGGATGCGGCGATCGAAGTCGCCTATATGGTGCTTCGAGCGCCGCACTGGCCAGAGCG
CGGATTAGATCGACAGACAC

Product: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase

Products: NA

Alternate protein names: Mannose-6-phosphate isomerase; Phosphohexomutase; Phosphomannose isomerase; PMI; Mannose-1-phosphate guanylyl transferase; GDP-mannose pyrophosphorylase; GMP; GMPP [H]

Number of amino acids: Translated: 513; Mature: 513

Protein sequence:

>513_residues
MNVIAEAVSPDALTHDTQLACVVQPVVLAGGSGTRLWPLSREQCPKQLIGLTSEESLLEATLRRTLGLSAPTRERPAPHA
IRTQPTLVVCSEELRLPTKERLDRCTSDSRVVLEPAPRNTAPALTVAALAARAAAPEGEDPVLVVMPADHLIADSQAFVA
TLQHAIQHALHDAIVTLGVPPERPETGYGYIKTGAPADGRGARTIERFVEKPAQQTAEQYVASGEYWWNSGIFVMRASVW
LAAIEACRHDIAAACQASYEQAKLDGDGTLHIDHAAFADCPSDSIDYAVMERIGDNPTLTGVIVPLTAGWSDVGAWDAVW
DVSAKDDAGNVARGRVLLEGSKDTYAHSEGRLVACVGVTGVVVVETADAVLVAAKDRVQDVKAIVNRLNAAKDTEAKVHR
KVERPWGCYDSIDRGERFQVKRIVVKPGGQLSLQMHHHRAEHWIVVRGTARVTRGDETFLITENQSTYIPLGTLHRLENP
GKTPLEIIEVQSGGYLGEDDIVRFDDRYGRTGS

Sequences:

>Translated_513_residues
MNVIAEAVSPDALTHDTQLACVVQPVVLAGGSGTRLWPLSREQCPKQLIGLTSEESLLEATLRRTLGLSAPTRERPAPHA
IRTQPTLVVCSEELRLPTKERLDRCTSDSRVVLEPAPRNTAPALTVAALAARAAAPEGEDPVLVVMPADHLIADSQAFVA
TLQHAIQHALHDAIVTLGVPPERPETGYGYIKTGAPADGRGARTIERFVEKPAQQTAEQYVASGEYWWNSGIFVMRASVW
LAAIEACRHDIAAACQASYEQAKLDGDGTLHIDHAAFADCPSDSIDYAVMERIGDNPTLTGVIVPLTAGWSDVGAWDAVW
DVSAKDDAGNVARGRVLLEGSKDTYAHSEGRLVACVGVTGVVVVETADAVLVAAKDRVQDVKAIVNRLNAAKDTEAKVHR
KVERPWGCYDSIDRGERFQVKRIVVKPGGQLSLQMHHHRAEHWIVVRGTARVTRGDETFLITENQSTYIPLGTLHRLENP
GKTPLEIIEVQSGGYLGEDDIVRFDDRYGRTGS
>Mature_513_residues
MNVIAEAVSPDALTHDTQLACVVQPVVLAGGSGTRLWPLSREQCPKQLIGLTSEESLLEATLRRTLGLSAPTRERPAPHA
IRTQPTLVVCSEELRLPTKERLDRCTSDSRVVLEPAPRNTAPALTVAALAARAAAPEGEDPVLVVMPADHLIADSQAFVA
TLQHAIQHALHDAIVTLGVPPERPETGYGYIKTGAPADGRGARTIERFVEKPAQQTAEQYVASGEYWWNSGIFVMRASVW
LAAIEACRHDIAAACQASYEQAKLDGDGTLHIDHAAFADCPSDSIDYAVMERIGDNPTLTGVIVPLTAGWSDVGAWDAVW
DVSAKDDAGNVARGRVLLEGSKDTYAHSEGRLVACVGVTGVVVVETADAVLVAAKDRVQDVKAIVNRLNAAKDTEAKVHR
KVERPWGCYDSIDRGERFQVKRIVVKPGGQLSLQMHHHRAEHWIVVRGTARVTRGDETFLITENQSTYIPLGTLHRLENP
GKTPLEIIEVQSGGYLGEDDIVRFDDRYGRTGS

Specific function: Involved in xanthan production [H]

COG id: COG0836

COG function: function code M; Mannose-1-phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannose-6-phosphate isomerase type 2 family [H]

Homologues:

Organism=Escherichia coli, GI1788362, Length=494, Percent_Identity=48.582995951417, Blast_Score=449, Evalue=1e-127,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR006375
- InterPro:   IPR001538
- InterPro:   IPR005835
- InterPro:   IPR014710 [H]

Pfam domain/function: PF01050 MannoseP_isomer; PF00483 NTP_transferase [H]

EC number: =5.3.1.8; =2.7.7.13 [H]

Molecular weight: Translated: 55582; Mature: 55582

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVIAEAVSPDALTHDTQLACVVQPVVLAGGSGTRLWPLSREQCPKQLIGLTSEESLLEA
CCCCHHHCCCCCCCCCCEEEEEEEEEEEECCCCCEEECCCHHHHHHHHHCCCCHHHHHHH
TLRRTLGLSAPTRERPAPHAIRTQPTLVVCSEELRLPTKERLDRCTSDSRVVLEPAPRNT
HHHHHHCCCCCCCCCCCCCCCCCCCEEEEECHHHCCCHHHHHHHCCCCCEEEECCCCCCC
APALTVAALAARAAAPEGEDPVLVVMPADHLIADSQAFVATLQHAIQHALHDAIVTLGVP
CCHHHHHHHHHHHCCCCCCCCEEEEECCHHHHCCCHHHHHHHHHHHHHHHHHHEEEECCC
PERPETGYGYIKTGAPADGRGARTIERFVEKPAQQTAEQYVASGEYWWNSGIFVMRASVW
CCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCEEEEHHHHH
LAAIEACRHDIAAACQASYEQAKLDGDGTLHIDHAAFADCPSDSIDYAVMERIGDNPTLT
HHHHHHHHHHHHHHHHHHHHHHEECCCCEEEECCHHHCCCCCCCCCHHHHHHCCCCCCEE
GVIVPLTAGWSDVGAWDAVWDVSAKDDAGNVARGRVLLEGSKDTYAHSEGRLVACVGVTG
EEEEEEECCCCCCCCCCCEEECCCCCCCCCCEECEEEEECCCCCCCCCCCCEEEEECCCE
VVVVETADAVLVAAKDRVQDVKAIVNRLNAAKDTEAKVHRKVERPWGCYDSIDRGERFQV
EEEEEECCEEEEECHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCCEEE
KRIVVKPGGQLSLQMHHHRAEHWIVVRGTARVTRGDETFLITENQSTYIPLGTLHRLENP
EEEEECCCCCEEEEEECCCCCEEEEEECCEEEECCCCEEEEECCCCCEECHHHHHHCCCC
GKTPLEIIEVQSGGYLGEDDIVRFDDRYGRTGS
CCCCEEEEEEECCCCCCCCCEEEECCCCCCCCC
>Mature Secondary Structure
MNVIAEAVSPDALTHDTQLACVVQPVVLAGGSGTRLWPLSREQCPKQLIGLTSEESLLEA
CCCCHHHCCCCCCCCCCEEEEEEEEEEEECCCCCEEECCCHHHHHHHHHCCCCHHHHHHH
TLRRTLGLSAPTRERPAPHAIRTQPTLVVCSEELRLPTKERLDRCTSDSRVVLEPAPRNT
HHHHHHCCCCCCCCCCCCCCCCCCCEEEEECHHHCCCHHHHHHHCCCCCEEEECCCCCCC
APALTVAALAARAAAPEGEDPVLVVMPADHLIADSQAFVATLQHAIQHALHDAIVTLGVP
CCHHHHHHHHHHHCCCCCCCCEEEEECCHHHHCCCHHHHHHHHHHHHHHHHHHEEEECCC
PERPETGYGYIKTGAPADGRGARTIERFVEKPAQQTAEQYVASGEYWWNSGIFVMRASVW
CCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCEEEEHHHHH
LAAIEACRHDIAAACQASYEQAKLDGDGTLHIDHAAFADCPSDSIDYAVMERIGDNPTLT
HHHHHHHHHHHHHHHHHHHHHHEECCCCEEEECCHHHCCCCCCCCCHHHHHHCCCCCCEE
GVIVPLTAGWSDVGAWDAVWDVSAKDDAGNVARGRVLLEGSKDTYAHSEGRLVACVGVTG
EEEEEEECCCCCCCCCCCEEECCCCCCCCCCEECEEEEECCCCCCCCCCCCEEEEECCCE
VVVVETADAVLVAAKDRVQDVKAIVNRLNAAKDTEAKVHRKVERPWGCYDSIDRGERFQV
EEEEEECCEEEEECHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCCEEE
KRIVVKPGGQLSLQMHHHRAEHWIVVRGTARVTRGDETFLITENQSTYIPLGTLHRLENP
EEEEECCCCCEEEEEECCCCCEEEEEECCEEEECCCCEEEEECCCCCEECHHHHHHCCCC
GKTPLEIIEVQSGGYLGEDDIVRFDDRYGRTGS
CCCCEEEEEEECCCCCCCCCEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1370280; 11589581 [H]