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The map label for this gene is qor [H]

Identifier: 186476814

GI number: 186476814

Start: 2312179

End: 2313153

Strand: Reverse

Name: qor [H]

Synonym: Bphy_2060

Alternate gene names: 186476814

Gene position: 2313153-2312179 (Counterclockwise)

Preceding gene: 186476815

Following gene: 186476813

Centisome position: 66.49

GC content: 65.13

Gene sequence:

>975_bases
ATGACCAAAGCAATTCGATTCGACAAGACGGGCGGACCGGAAGTGATGAAGTGGGTCGACGTCGACGTGGGCGCGCCGGG
TAGTGGCGAGATCCGTATCAGGCAGCATGCTGTCGGCTTGAACTATATCGACGTGTATTTCCGCACCGGGCTGTATCCGT
TGCCGCTGCCGGGCGGGCTCGGCATGGAAGCGGCGGGCGAGGTGGTCGCCGTTGGCCCGGACGTGACTGACGTGAAAGTG
GGTGAGCGCGTCGCGTATGTTGCGCGGCCGCCGGGCGCGTATGCGCAGGAACGCGTGCTGCCCGCGGCCCAGGTCGTGAA
GCTGCCCGACGCGATCGGCTATGAGGAGGCGGCCTCCGTCATGCTGCAGGGCTTGACCGCGCAATATCTGCTGCGCCGCA
CGTACCCGGTGAAGCAGGGCGACACGATCCTGATCCAGGCGGCCGCGGGCGGCGTCGGCCTGCTCGTGTGCCAGTGGGCC
AAGGCGCTGGGCGCGACGGTGATCGGCACGGTCAGCTCGGACGAGAAGGCGGAGATCGCGCAGGCGCACGGCTGCGACTA
TCCCATCGTGTACACGCGCGAGAACTTCACGAAGCGTGTGCGCGAGATCACGAACGGCGCAGGCGTGCCCGTCGTGTACG
ACTCGATCGGCAAGGATACCTTTACGGCCTCGCTCGATTGTCTTGCGCCGCTTGGGATGTTCGTGAGCTTCGGCAATGCG
TCGGGCCCGTTGCCGCCGATCGATTCGTCGGAGTTCGCCGGGCGCGGCTCGCTGTTCTTCACGCGTCCAACACTCTTTAC
CTATATGGGCAAGCGCAGCGACTACGACGCGATGGCGGCGGAGCTGTTCGACGTCATCGGCTCAGGTAAGGTGAAGACGA
GCATCAATCAGCGCTATGCGCTGTCCGATGTCGGCAAGGCGCACGCCGATCTGGAGGCGCGGAAAACGACCGGCTCGACG
GTTTTGCTGCCCTGA

Upstream 100 bases:

>100_bases
GACGTGCTGACGCTGCGTCTCACTCAGCAGGTCTGATCACGTTGTCCGATTTCAATCATGCAATGCTCGCCACTCGGCCG
CGAGCGAATCTGGAGACAAC

Downstream 100 bases:

>100_bases
AGCGTTTGGCCGGGCGAGCACAAATTCGACTACTGGTTCGCGAATTACGGCGCCGTAACGGACTGCACATCAATACTGCG
CGTAGACGAGGGAGCCACCG

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: NADPH:quinone reductase [H]

Number of amino acids: Translated: 324; Mature: 323

Protein sequence:

>324_residues
MTKAIRFDKTGGPEVMKWVDVDVGAPGSGEIRIRQHAVGLNYIDVYFRTGLYPLPLPGGLGMEAAGEVVAVGPDVTDVKV
GERVAYVARPPGAYAQERVLPAAQVVKLPDAIGYEEAASVMLQGLTAQYLLRRTYPVKQGDTILIQAAAGGVGLLVCQWA
KALGATVIGTVSSDEKAEIAQAHGCDYPIVYTRENFTKRVREITNGAGVPVVYDSIGKDTFTASLDCLAPLGMFVSFGNA
SGPLPPIDSSEFAGRGSLFFTRPTLFTYMGKRSDYDAMAAELFDVIGSGKVKTSINQRYALSDVGKAHADLEARKTTGST
VLLP

Sequences:

>Translated_324_residues
MTKAIRFDKTGGPEVMKWVDVDVGAPGSGEIRIRQHAVGLNYIDVYFRTGLYPLPLPGGLGMEAAGEVVAVGPDVTDVKV
GERVAYVARPPGAYAQERVLPAAQVVKLPDAIGYEEAASVMLQGLTAQYLLRRTYPVKQGDTILIQAAAGGVGLLVCQWA
KALGATVIGTVSSDEKAEIAQAHGCDYPIVYTRENFTKRVREITNGAGVPVVYDSIGKDTFTASLDCLAPLGMFVSFGNA
SGPLPPIDSSEFAGRGSLFFTRPTLFTYMGKRSDYDAMAAELFDVIGSGKVKTSINQRYALSDVGKAHADLEARKTTGST
VLLP
>Mature_323_residues
TKAIRFDKTGGPEVMKWVDVDVGAPGSGEIRIRQHAVGLNYIDVYFRTGLYPLPLPGGLGMEAAGEVVAVGPDVTDVKVG
ERVAYVARPPGAYAQERVLPAAQVVKLPDAIGYEEAASVMLQGLTAQYLLRRTYPVKQGDTILIQAAAGGVGLLVCQWAK
ALGATVIGTVSSDEKAEIAQAHGCDYPIVYTRENFTKRVREITNGAGVPVVYDSIGKDTFTASLDCLAPLGMFVSFGNAS
GPLPPIDSSEFAGRGSLFFTRPTLFTYMGKRSDYDAMAAELFDVIGSGKVKTSINQRYALSDVGKAHADLEARKTTGSTV
LLP

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI22538446, Length=333, Percent_Identity=30.9309309309309, Blast_Score=135, Evalue=7e-32,
Organism=Homo sapiens, GI22538444, Length=333, Percent_Identity=30.9309309309309, Blast_Score=135, Evalue=7e-32,
Organism=Homo sapiens, GI194239674, Length=329, Percent_Identity=28.2674772036474, Blast_Score=127, Evalue=1e-29,
Organism=Homo sapiens, GI13236495, Length=329, Percent_Identity=28.2674772036474, Blast_Score=127, Evalue=1e-29,
Organism=Homo sapiens, GI18379349, Length=313, Percent_Identity=29.073482428115, Blast_Score=125, Evalue=7e-29,
Organism=Homo sapiens, GI28557745, Length=226, Percent_Identity=35.3982300884956, Blast_Score=115, Evalue=5e-26,
Organism=Homo sapiens, GI194239676, Length=264, Percent_Identity=28.030303030303, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI24308257, Length=322, Percent_Identity=27.639751552795, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI41872631, Length=215, Percent_Identity=32.093023255814, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI197927207, Length=195, Percent_Identity=25.1282051282051, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1790485, Length=327, Percent_Identity=46.177370030581, Blast_Score=289, Evalue=2e-79,
Organism=Caenorhabditis elegans, GI17507255, Length=317, Percent_Identity=26.813880126183, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17556000, Length=218, Percent_Identity=29.3577981651376, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17536829, Length=307, Percent_Identity=24.4299674267101, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6319520, Length=324, Percent_Identity=40.4320987654321, Blast_Score=226, Evalue=4e-60,
Organism=Saccharomyces cerevisiae, GI6323729, Length=340, Percent_Identity=25.8823529411765, Blast_Score=78, Evalue=2e-15,
Organism=Drosophila melanogaster, GI45550423, Length=304, Percent_Identity=24.6710526315789, Blast_Score=69, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 34443; Mature: 34312

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: PS01162 QOR_ZETA_CRYSTAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKAIRFDKTGGPEVMKWVDVDVGAPGSGEIRIRQHAVGLNYIDVYFRTGLYPLPLPGGL
CCCCEECCCCCCCCEEEEEEEECCCCCCCCEEEEEEECCCCCEEEHHHCCCCCCCCCCCC
GMEAAGEVVAVGPDVTDVKVGERVAYVARPPGAYAQERVLPAAQVVKLPDAIGYEEAASV
CCCCCCCEEEECCCCCEEECCCEEEEEECCCCCHHHHHCCCHHHHHHCCCCCCHHHHHHH
MLQGLTAQYLLRRTYPVKQGDTILIQAAAGGVGLLVCQWAKALGATVIGTVSSDEKAEIA
HHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCEEEEECCCCCHHHHH
QAHGCDYPIVYTRENFTKRVREITNGAGVPVVYDSIGKDTFTASLDCLAPLGMFVSFGNA
HHCCCCCCEEEECHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHEECCCC
SGPLPPIDSSEFAGRGSLFFTRPTLFTYMGKRSDYDAMAAELFDVIGSGKVKTSINQRYA
CCCCCCCCCCCCCCCCCEEEECCHHHHHHCCCCCHHHHHHHHHHHHCCCCEEECCCCCEE
LSDVGKAHADLEARKTTGSTVLLP
HHHHHHHHCCCHHHCCCCCEEECC
>Mature Secondary Structure 
TKAIRFDKTGGPEVMKWVDVDVGAPGSGEIRIRQHAVGLNYIDVYFRTGLYPLPLPGGL
CCCEECCCCCCCCEEEEEEEECCCCCCCCEEEEEEECCCCCEEEHHHCCCCCCCCCCCC
GMEAAGEVVAVGPDVTDVKVGERVAYVARPPGAYAQERVLPAAQVVKLPDAIGYEEAASV
CCCCCCCEEEECCCCCEEECCCEEEEEECCCCCHHHHHCCCHHHHHHCCCCCCHHHHHHH
MLQGLTAQYLLRRTYPVKQGDTILIQAAAGGVGLLVCQWAKALGATVIGTVSSDEKAEIA
HHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCEEEEECCCCCHHHHH
QAHGCDYPIVYTRENFTKRVREITNGAGVPVVYDSIGKDTFTASLDCLAPLGMFVSFGNA
HHCCCCCCEEEECHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHEECCCC
SGPLPPIDSSEFAGRGSLFFTRPTLFTYMGKRSDYDAMAAELFDVIGSGKVKTSINQRYA
CCCCCCCCCCCCCCCCCEEEECCHHHHHHCCCCCHHHHHHHHHHHHCCCCEEECCCCCEE
LSDVGKAHADLEARKTTGSTVLLP
HHHHHHHHCCCHHHCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]