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The map label for this gene is kdpE [H]

Identifier: 186476807

GI number: 186476807

Start: 2302883

End: 2303581

Strand: Reverse

Name: kdpE [H]

Synonym: Bphy_2053

Alternate gene names: 186476807

Gene position: 2303581-2302883 (Counterclockwise)

Preceding gene: 186476808

Following gene: 186476806

Centisome position: 66.21

GC content: 65.52

Gene sequence:

>699_bases
ATGAGCGACCTGAGCATTACCGTCGTACTGATCGAAGACGAACAACAGATTCGCCGCTTCGTGCGGGCGTCACTGGAAGG
CGAGGGGATGACCGTGTACGACGCGCCGACGGGCAAACAGGGACTAATCGAAGCGGCCACACGCAAGCCCGATCTCGTGA
TCGTCGATCTGGGCTTGCCCGACACCGATGGCCTCGACGTGATCCGCGAACTGCGCGGCTGGAGCGAGTTGCCCATCATC
GTGCTGTCGGCGCGCACGCAGGAGAGCGAGAAGGTCGCGGCGCTCGATGCCGGCGCCGACGACTATCTGACCAAGCCGTT
TGGCGTGTCCGAGTTATTTGCGCGGATCCGCGCGCATCTACGCCGGCGCAACCAGGGTGGTCCGGCCGAGACGCCGCAGG
TGCAGTTCGGCGGCGTGACCGTCGATCTGGCCTTGCGGCAGGTCTCGCGCGACGGCGAGCCCGTGCATCTGACGCCGCTC
GAATACCGGCTGCTCGCGACGCTCGTGCGTCATGCGGGGCGCGTGCTCACGCATCGCCAGTTGCTGCGCGACGTGTGGGG
CCCGTCGCACGTCGAAAGCCATCACTATCTGCGCATCTACATGGCGCATTTGCGGCAGAAACTGGAACGCGATCCGGCGC
AGCCCGAGCATATCGTCACGGAGACGGGCGTCGGATATCGGCTGGTTGGCGTCGCGTGA

Upstream 100 bases:

>100_bases
CCGTGCCCGACGTATCCGATCTGCCCGACGAAGCCGCGGCCGAGCCGGATCCCGAACCGCACCGTCGACAACAAGCCGAT
ACGCATCCTCATACTCACTC

Downstream 100 bases:

>100_bases
CGCGACGCAGTGTTGCGGCGTTTCATATTGGATCGCATATGCCCGACAGTGAAATGCACGCCATCTTGATATAATGGCGG
TCGGCAAGGACGGCCTTGCT

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 232; Mature: 231

Protein sequence:

>232_residues
MSDLSITVVLIEDEQQIRRFVRASLEGEGMTVYDAPTGKQGLIEAATRKPDLVIVDLGLPDTDGLDVIRELRGWSELPII
VLSARTQESEKVAALDAGADDYLTKPFGVSELFARIRAHLRRRNQGGPAETPQVQFGGVTVDLALRQVSRDGEPVHLTPL
EYRLLATLVRHAGRVLTHRQLLRDVWGPSHVESHHYLRIYMAHLRQKLERDPAQPEHIVTETGVGYRLVGVA

Sequences:

>Translated_232_residues
MSDLSITVVLIEDEQQIRRFVRASLEGEGMTVYDAPTGKQGLIEAATRKPDLVIVDLGLPDTDGLDVIRELRGWSELPII
VLSARTQESEKVAALDAGADDYLTKPFGVSELFARIRAHLRRRNQGGPAETPQVQFGGVTVDLALRQVSRDGEPVHLTPL
EYRLLATLVRHAGRVLTHRQLLRDVWGPSHVESHHYLRIYMAHLRQKLERDPAQPEHIVTETGVGYRLVGVA
>Mature_231_residues
SDLSITVVLIEDEQQIRRFVRASLEGEGMTVYDAPTGKQGLIEAATRKPDLVIVDLGLPDTDGLDVIRELRGWSELPIIV
LSARTQESEKVAALDAGADDYLTKPFGVSELFARIRAHLRRRNQGGPAETPQVQFGGVTVDLALRQVSRDGEPVHLTPLE
YRLLATLVRHAGRVLTHRQLLRDVWGPSHVESHHYLRIYMAHLRQKLERDPAQPEHIVTETGVGYRLVGVA

Specific function: Member of the two-component regulatory system kdpD/kdpE involved in the regulation of the kdp operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786911, Length=223, Percent_Identity=63.677130044843, Blast_Score=296, Evalue=1e-81,
Organism=Escherichia coli, GI1787375, Length=220, Percent_Identity=37.2727272727273, Blast_Score=137, Evalue=5e-34,
Organism=Escherichia coli, GI1786784, Length=226, Percent_Identity=35.8407079646018, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI87082012, Length=226, Percent_Identity=33.1858407079646, Blast_Score=127, Evalue=5e-31,
Organism=Escherichia coli, GI1789809, Length=231, Percent_Identity=33.3333333333333, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1790552, Length=226, Percent_Identity=34.9557522123894, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1790860, Length=226, Percent_Identity=34.5132743362832, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI1788394, Length=225, Percent_Identity=33.3333333333333, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI1789402, Length=226, Percent_Identity=37.1681415929204, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1786599, Length=225, Percent_Identity=33.3333333333333, Blast_Score=117, Evalue=4e-28,
Organism=Escherichia coli, GI1790863, Length=229, Percent_Identity=31.0043668122271, Blast_Score=110, Evalue=9e-26,
Organism=Escherichia coli, GI2367329, Length=231, Percent_Identity=31.1688311688312, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1787229, Length=231, Percent_Identity=32.4675324675325, Blast_Score=104, Evalue=4e-24,
Organism=Escherichia coli, GI145693140, Length=229, Percent_Identity=31.0043668122271, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1788550, Length=106, Percent_Identity=31.1320754716981, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1790299, Length=138, Percent_Identity=31.1594202898551, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1790437, Length=143, Percent_Identity=30.0699300699301, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25886; Mature: 25755

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDLSITVVLIEDEQQIRRFVRASLEGEGMTVYDAPTGKQGLIEAATRKPDLVIVDLGLP
CCCCEEEEEEECCHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHCCCCCEEEEECCCC
DTDGLDVIRELRGWSELPIIVLSARTQESEKVAALDAGADDYLTKPFGVSELFARIRAHL
CCCHHHHHHHHCCCCCCCEEEEECCCCCCCCEEEECCCCCHHCCCCCCHHHHHHHHHHHH
RRRNQGGPAETPQVQFGGVTVDLALRQVSRDGEPVHLTPLEYRLLATLVRHAGRVLTHRQ
HHCCCCCCCCCCCEEECCEEHHHHHHHHHCCCCCEEECHHHHHHHHHHHHHHHHHHHHHH
LLRDVWGPSHVESHHYLRIYMAHLRQKLERDPAQPEHIVTETGVGYRLVGVA
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCEEEEEEC
>Mature Secondary Structure 
SDLSITVVLIEDEQQIRRFVRASLEGEGMTVYDAPTGKQGLIEAATRKPDLVIVDLGLP
CCCEEEEEEECCHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHCCCCCEEEEECCCC
DTDGLDVIRELRGWSELPIIVLSARTQESEKVAALDAGADDYLTKPFGVSELFARIRAHL
CCCHHHHHHHHCCCCCCCEEEEECCCCCCCCEEEECCCCCHHCCCCCCHHHHHHHHHHHH
RRRNQGGPAETPQVQFGGVTVDLALRQVSRDGEPVHLTPLEYRLLATLVRHAGRVLTHRQ
HHCCCCCCCCCCCEEECCEEHHHHHHHHHCCCCCEEECHHHHHHHHHHHHHHHHHHHHHH
LLRDVWGPSHVESHHYLRIYMAHLRQKLERDPAQPEHIVTETGVGYRLVGVA
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1532388; 8905232; 9278503 [H]