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The map label for this gene is nuoC

Identifier: 186476762

GI number: 186476762

Start: 2258805

End: 2259407

Strand: Reverse

Name: nuoC

Synonym: Bphy_2007

Alternate gene names: 186476762

Gene position: 2259407-2258805 (Counterclockwise)

Preceding gene: 186476763

Following gene: 186476761

Centisome position: 64.94

GC content: 59.37

Gene sequence:

>603_bases
ATGGCAAGCAAACTCGAGACCCTCAAAGCGAACCTCGAGGCGGCCTTTGGCGGCCGCCTGACGAGCATCACCGAATCGAT
CGGTGAGCTGACCATCGTCGTGAAGGCAGACGATTTCCTCGAAGTGGCCACGCGTCTGCGCGACGATGCGAAATTGCATT
TCGAACAGCTGATCGACCTCTGCGGCATCGACTATCAAACCTACGGTGAAGGCGCTTACGACGGTCCGCGTTTTGCCGCC
GTCCTGCATCTGCTGTCCATTACGAACAACTGGCGCCTGCGTGTGCGCGTGTTCGCACCCGACGACGACGTGCCGCTCAT
TCCCTCCGTCGTCGAGATCTGGAATTCAGCCAACTGGTACGAGCGCGAAGCGTTCGATCTGTACGGCATTGTGTTCGAAG
GTCACCCCGACCTGCGCCGCATCCTGACCGATTACGGTTTCATCGGTCACCCGTTCCGCAAGGATTTCCCTGTCTCCGGC
TATGTCGAGATGCGTTACGACCCGGAAGAGAAGCGCGTCGTCTATCAGCCGGTGACGATCGAGCCTCGGGAAATCACGCC
GCGCGTGATCCGCGAGGATCGCTATGGCGGCCTGAAACACTAA

Upstream 100 bases:

>100_bases
GCCTACGGCTGAAGCGCTGGTGTACGGCGTGATCCAGCTGCAGGCAAAGATCCGCCGCACCAACACCATCGCCCGTCAAT
AAGCCGAAGCCCCCCACAAT

Downstream 100 bases:

>100_bases
GAGAACGTCATGGCAGAGATCAAGAACTACACGCTCAACTTCGGTCCGCAGCACCCGGCAGCGCACGGCGTGTTGCGCCT
CGTGCTGGAACTCGACGGCG

Product: NADH dehydrogenase subunit C

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C; NDH-1 subunit C

Number of amino acids: Translated: 200; Mature: 199

Protein sequence:

>200_residues
MASKLETLKANLEAAFGGRLTSITESIGELTIVVKADDFLEVATRLRDDAKLHFEQLIDLCGIDYQTYGEGAYDGPRFAA
VLHLLSITNNWRLRVRVFAPDDDVPLIPSVVEIWNSANWYEREAFDLYGIVFEGHPDLRRILTDYGFIGHPFRKDFPVSG
YVEMRYDPEEKRVVYQPVTIEPREITPRVIREDRYGGLKH

Sequences:

>Translated_200_residues
MASKLETLKANLEAAFGGRLTSITESIGELTIVVKADDFLEVATRLRDDAKLHFEQLIDLCGIDYQTYGEGAYDGPRFAA
VLHLLSITNNWRLRVRVFAPDDDVPLIPSVVEIWNSANWYEREAFDLYGIVFEGHPDLRRILTDYGFIGHPFRKDFPVSG
YVEMRYDPEEKRVVYQPVTIEPREITPRVIREDRYGGLKH
>Mature_199_residues
ASKLETLKANLEAAFGGRLTSITESIGELTIVVKADDFLEVATRLRDDAKLHFEQLIDLCGIDYQTYGEGAYDGPRFAAV
LHLLSITNNWRLRVRVFAPDDDVPLIPSVVEIWNSANWYEREAFDLYGIVFEGHPDLRRILTDYGFIGHPFRKDFPVSGY
VEMRYDPEEKRVVYQPVTIEPREITPRVIREDRYGGLKH

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0852

COG function: function code C; NADH:ubiquinone oxidoreductase 27 kD subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 30 kDa subunit family

Homologues:

Organism=Homo sapiens, GI4758788, Length=155, Percent_Identity=48.3870967741936, Blast_Score=147, Evalue=5e-36,
Organism=Escherichia coli, GI145693162, Length=162, Percent_Identity=33.9506172839506, Blast_Score=88, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI71990788, Length=149, Percent_Identity=43.6241610738255, Blast_Score=130, Evalue=5e-31,
Organism=Caenorhabditis elegans, GI32563621, Length=149, Percent_Identity=43.6241610738255, Blast_Score=130, Evalue=5e-31,
Organism=Drosophila melanogaster, GI24656494, Length=152, Percent_Identity=44.7368421052632, Blast_Score=138, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUOC_BURP8 (B2JDM6)

Other databases:

- EMBL:   CP001043
- RefSeq:   YP_001858232.1
- ProteinModelPortal:   B2JDM6
- SMR:   B2JDM6
- GeneID:   6243496
- GenomeReviews:   CP001043_GR
- KEGG:   bph:Bphy_2007
- HOGENOM:   HBG727675
- OMA:   VFAPDDD
- ProtClustDB:   PRK06074
- GO:   GO:0006810
- HAMAP:   MF_01357
- InterPro:   IPR010218
- InterPro:   IPR001268
- InterPro:   IPR020396
- ProDom:   PD001581
- TIGRFAMs:   TIGR01961

Pfam domain/function: PF00329 Complex1_30kDa

EC number: =1.6.99.5

Molecular weight: Translated: 23007; Mature: 22876

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS00542 COMPLEX1_30K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASKLETLKANLEAAFGGRLTSITESIGELTIVVKADDFLEVATRLRDDAKLHFEQLIDL
CCCHHHHHHHHHHHHCCCHHHHHHHHHCCEEEEEECCHHHHHHHHHCCCHHHHHHHHHHH
CGIDYQTYGEGAYDGPRFAAVLHLLSITNNWRLRVRVFAPDDDVPLIPSVVEIWNSANWY
HCCCCEECCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHCCCCCC
EREAFDLYGIVFEGHPDLRRILTDYGFIGHPFRKDFPVSGYVEMRYDPEEKRVVYQPVTI
CCCCEEEEEEEECCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCEEEECCCCC
EPREITPRVIREDRYGGLKH
CCHHCCHHHHHCCCCCCCCC
>Mature Secondary Structure 
ASKLETLKANLEAAFGGRLTSITESIGELTIVVKADDFLEVATRLRDDAKLHFEQLIDL
CCHHHHHHHHHHHHCCCHHHHHHHHHCCEEEEEECCHHHHHHHHHCCCHHHHHHHHHHH
CGIDYQTYGEGAYDGPRFAAVLHLLSITNNWRLRVRVFAPDDDVPLIPSVVEIWNSANWY
HCCCCEECCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHCCCCCC
EREAFDLYGIVFEGHPDLRRILTDYGFIGHPFRKDFPVSGYVEMRYDPEEKRVVYQPVTI
CCCCEEEEEEEECCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCEEEECCCCC
EPREITPRVIREDRYGGLKH
CCHHCCHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA