Click here to switch to the map view.

The map label for this gene is hmrR2 [H]

Identifier: 186476722

GI number: 186476722

Start: 2210644

End: 2211069

Strand: Reverse

Name: hmrR2 [H]

Synonym: Bphy_1967

Alternate gene names: 186476722

Gene position: 2211069-2210644 (Counterclockwise)

Preceding gene: 186476725

Following gene: 186476721

Centisome position: 63.55

GC content: 63.38

Gene sequence:

>426_bases
ATGAATATCGGTGAAGCGGCCCGCGCGTCGGGCGTGACGGCGAAGATGATCCGCTACTACGAGAGCGTGGGATTGCTCGC
CGCAAAGGAGCGTACGGCGGCAGGGTATCGTGTTTACGGCGCGCCGGAAGTCCATTCGCTGCGTTTTATCCGCCAGGCGC
GGCGGCTGGGGTTTCTGGTCGAGGATATCCGCAGGCTGCTCGCGCTGTGGAACGACCGGTCGCGAGCGAGCGCCGAGGTG
AAGTCAATCGCGCTACAGCATGTCGCCGAACTGAACCGCCGGATCGCTGAACTGACTGCGATGCGCGACACACTGACGCA
TCTCGCCGAGCATTGCCACGGCGACGATCGCCCCGATTGTCCGATCATCGAAAGCCTGGCGGCTGCCGATTCGACGATCG
CTACGCCGGATTGTCACGGCCATTGA

Upstream 100 bases:

>100_bases
TTGAATTATGCCTGTCGACGGGCCATATCATGATTAACCTTCCCACAGTGGGAAGGTCAAGAATCATGCAACATACGTGT
AGCAAAGTGGGGAAAGAGTG

Downstream 100 bases:

>100_bases
AAAACAGTGCCGCAGCGTAGAGATCAGTCGAACATAATGCACTTATGTGGTGCAAAAATAAGGTTGGGGTCAACGGATTT
TCCCGCGGGTCTCTAAAAAC

Product: MerR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 141; Mature: 141

Protein sequence:

>141_residues
MNIGEAARASGVTAKMIRYYESVGLLAAKERTAAGYRVYGAPEVHSLRFIRQARRLGFLVEDIRRLLALWNDRSRASAEV
KSIALQHVAELNRRIAELTAMRDTLTHLAEHCHGDDRPDCPIIESLAAADSTIATPDCHGH

Sequences:

>Translated_141_residues
MNIGEAARASGVTAKMIRYYESVGLLAAKERTAAGYRVYGAPEVHSLRFIRQARRLGFLVEDIRRLLALWNDRSRASAEV
KSIALQHVAELNRRIAELTAMRDTLTHLAEHCHGDDRPDCPIIESLAAADSTIATPDCHGH
>Mature_141_residues
MNIGEAARASGVTAKMIRYYESVGLLAAKERTAAGYRVYGAPEVHSLRFIRQARRLGFLVEDIRRLLALWNDRSRASAEV
KSIALQHVAELNRRIAELTAMRDTLTHLAEHCHGDDRPDCPIIESLAAADSTIATPDCHGH

Specific function: Transcriptional regulator involved in acid tolerance. Binds copper [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786695, Length=128, Percent_Identity=46.875, Blast_Score=122, Evalue=6e-30,
Organism=Escherichia coli, GI1789687, Length=136, Percent_Identity=36.7647058823529, Blast_Score=86, Evalue=9e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011789
- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR015358 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 15618; Mature: 15618

Theoretical pI: Translated: 8.11; Mature: 8.11

Prosite motif: PS00552 HTH_MERR_1 ; PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIGEAARASGVTAKMIRYYESVGLLAAKERTAAGYRVYGAPEVHSLRFIRQARRLGFLV
CCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHH
EDIRRLLALWNDRSRASAEVKSIALQHVAELNRRIAELTAMRDTLTHLAEHCHGDDRPDC
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PIIESLAAADSTIATPDCHGH
HHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MNIGEAARASGVTAKMIRYYESVGLLAAKERTAAGYRVYGAPEVHSLRFIRQARRLGFLV
CCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHH
EDIRRLLALWNDRSRASAEVKSIALQHVAELNRRIAELTAMRDTLTHLAEHCHGDDRPDC
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PIIESLAAADSTIATPDCHGH
HHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481431 [H]