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The map label for this gene is sppA [H]

Identifier: 186476640

GI number: 186476640

Start: 2142519

End: 2143397

Strand: Reverse

Name: sppA [H]

Synonym: Bphy_1885

Alternate gene names: 186476640

Gene position: 2143397-2142519 (Counterclockwise)

Preceding gene: 186476641

Following gene: 186476639

Centisome position: 61.61

GC content: 60.18

Gene sequence:

>879_bases
ATGAAAACCTATCCGTTTGCAGCGGCGCGCGTGTTTGACGTGCCGCTGGCGATCCACCCCACCAAGGGACAGGTGATTGC
GAAGGTGCTCGCCGGTCGATTCGGAATTTCCGATGTCGAGTTCGCCGGCGAAGCGCCGGTTTTCGTGAAGCCGATGGCTT
ACGACGAGTGGGACGACGGCCCGAGCGAGCAATACGAAGAGACGCCGTATGACCTGACGCAGGGGGTTGCGGTCATCGAC
GTGTCGGGCACGCTCGTCCAGAAAAGCAGCAACCTTCGGCCGTATTCGGGGATGCTCGGTTACAACGCAATCCGCCACAA
CTTCCTTGCCGCGCTAGATGACAAGAAAGTGAAGGCGATCGTGCTGTCGATCGACTCGCCAGGCGGTGAAGTGGCTGGCT
GCTTCGATTTAGCCGACCTGATCTACGAATCGCGCAGCGTCAAGCCAACGCTTGCGATCCTGAACGAGTCCGGGTACAGC
GCTGCTTATGCGCTCGCAAGCGCATGCGAGCAGATCACGGTCCCGCGGACAGGCGGCACGGGCAGTGTCGGAGTGATCTG
CATGCACGTAGATCAGAGCAAGGCAATCGACAAGGCTGGGCTGACCGTCACGATCATCAAATACGGTGATCGCAAGGCCG
ACGGCAATCAGTTCAACCCGCTCTCGAAAGAGGCGCTCGACCGGTACCAGGCCGAAGTCGATGAAATGGGCGAACTCTTC
GTTCAGACGGTCGCTCGCAATCGCAACCTTTCCGCCGACGTCGTTCGAAAGACGCAGGCAACCACCTTTCTCGGTGCCGC
TGGTGTCGAGATCGGCTTCGCTGACGCCGTGATGGCGCCCGACGAAGCGTTTCGCTCCCTGCTCAAAGAGCTGGGCTGA

Upstream 100 bases:

>100_bases
CTCAGCGCGCCAAATGGACGCCTGAAATGCGAGCAGCACAGGCCGCGCGTACGCGTGCCCAGTTTGCTGCGAAGCGGGCG
TTAACCCAGAGCGAGTCTCA

Downstream 100 bases:

>100_bases
CATTTCCCCAACCCAAGAGGTTCACATATGAGTATTCGCACCCTCGCGGCGCGCGGGCTCTCGTTCGCCCATCTCGCCGG
CATCAAACCCCGCGGCGCGC

Product: peptidase S49

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MKTYPFAAARVFDVPLAIHPTKGQVIAKVLAGRFGISDVEFAGEAPVFVKPMAYDEWDDGPSEQYEETPYDLTQGVAVID
VSGTLVQKSSNLRPYSGMLGYNAIRHNFLAALDDKKVKAIVLSIDSPGGEVAGCFDLADLIYESRSVKPTLAILNESGYS
AAYALASACEQITVPRTGGTGSVGVICMHVDQSKAIDKAGLTVTIIKYGDRKADGNQFNPLSKEALDRYQAEVDEMGELF
VQTVARNRNLSADVVRKTQATTFLGAAGVEIGFADAVMAPDEAFRSLLKELG

Sequences:

>Translated_292_residues
MKTYPFAAARVFDVPLAIHPTKGQVIAKVLAGRFGISDVEFAGEAPVFVKPMAYDEWDDGPSEQYEETPYDLTQGVAVID
VSGTLVQKSSNLRPYSGMLGYNAIRHNFLAALDDKKVKAIVLSIDSPGGEVAGCFDLADLIYESRSVKPTLAILNESGYS
AAYALASACEQITVPRTGGTGSVGVICMHVDQSKAIDKAGLTVTIIKYGDRKADGNQFNPLSKEALDRYQAEVDEMGELF
VQTVARNRNLSADVVRKTQATTFLGAAGVEIGFADAVMAPDEAFRSLLKELG
>Mature_292_residues
MKTYPFAAARVFDVPLAIHPTKGQVIAKVLAGRFGISDVEFAGEAPVFVKPMAYDEWDDGPSEQYEETPYDLTQGVAVID
VSGTLVQKSSNLRPYSGMLGYNAIRHNFLAALDDKKVKAIVLSIDSPGGEVAGCFDLADLIYESRSVKPTLAILNESGYS
AAYALASACEQITVPRTGGTGSVGVICMHVDQSKAIDKAGLTVTIIKYGDRKADGNQFNPLSKEALDRYQAEVDEMGELF
VQTVARNRNLSADVVRKTQATTFLGAAGVEIGFADAVMAPDEAFRSLLKELG

Specific function: Digestion of cleaved signal peptides. Required for efficient processing of precursors under conditions of hyper-secretion [H]

COG id: COG0616

COG function: function code OU; Periplasmic serine proteases (ClpP class)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S49 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004635
- InterPro:   IPR002142 [H]

Pfam domain/function: PF01343 Peptidase_S49 [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 31313; Mature: 31313

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTYPFAAARVFDVPLAIHPTKGQVIAKVLAGRFGISDVEFAGEAPVFVKPMAYDEWDDG
CCCCCCCHHEEEECCEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCC
PSEQYEETPYDLTQGVAVIDVSGTLVQKSSNLRPYSGMLGYNAIRHNFLAALDDKKVKAI
CCHHHCCCCCHHHCCEEEEEECCEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEE
VLSIDSPGGEVAGCFDLADLIYESRSVKPTLAILNESGYSAAYALASACEQITVPRTGGT
EEEECCCCCCEEHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHEECCCCCCC
GSVGVICMHVDQSKAIDKAGLTVTIIKYGDRKADGNQFNPLSKEALDRYQAEVDEMGELF
CCEEEEEEEECCHHHHHHCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
VQTVARNRNLSADVVRKTQATTFLGAAGVEIGFADAVMAPDEAFRSLLKELG
HHHHHHCCCCCHHHHHHHHHHHEEECCCCEECCHHHHCCCHHHHHHHHHHCC
>Mature Secondary Structure
MKTYPFAAARVFDVPLAIHPTKGQVIAKVLAGRFGISDVEFAGEAPVFVKPMAYDEWDDG
CCCCCCCHHEEEECCEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCC
PSEQYEETPYDLTQGVAVIDVSGTLVQKSSNLRPYSGMLGYNAIRHNFLAALDDKKVKAI
CCHHHCCCCCHHHCCEEEEEECCEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEE
VLSIDSPGGEVAGCFDLADLIYESRSVKPTLAILNESGYSAAYALASACEQITVPRTGGT
EEEECCCCCCEEHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHEECCCCCCC
GSVGVICMHVDQSKAIDKAGLTVTIIKYGDRKADGNQFNPLSKEALDRYQAEVDEMGELF
CCEEEEEEEECCHHHHHHCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
VQTVARNRNLSADVVRKTQATTFLGAAGVEIGFADAVMAPDEAFRSLLKELG
HHHHHHCCCCCHHHHHHHHHHHEEECCCCEECCHHHHCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377; 10455123 [H]