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The map label for this gene is bkdR [H]

Identifier: 186476604

GI number: 186476604

Start: 2114425

End: 2115066

Strand: Direct

Name: bkdR [H]

Synonym: Bphy_1849

Alternate gene names: 186476604

Gene position: 2114425-2115066 (Clockwise)

Preceding gene: 186476602

Following gene: 186476606

Centisome position: 60.77

GC content: 61.68

Gene sequence:

>642_bases
ATGCGTCCGGAAAATGTGCGTCTCTTTTGCTTGCGCAGGCGCTTCCATATAGTGTATTTATTCTGGTATATCGGCTTTAC
ATGGAATATTTACACTATGGCTTCCGACGCCAGACATGCCGCCGCAGCGCGGCGCCTCGACCGCATCGACATCGCGATTC
TTCAGCAGCTCCAGCAGAACGCGCGCATCACGAATGCGGAACTCGCGCGCGCCGTCAATCTGTCGCCCACGCCCTGCTTC
AACCGCGTGCGCGCGCTCGAAAGACTCGGCCTGTTCCGTCAGCAGGTCACGCTGCTCGACGCGGAAGCACTCGGGCTGCG
CATCAACGTGTTCATTCAGGTGAGCCTCGAAAAGCAGGTCGAAGAGGCGTTGCGCCGCTTCGAGCAGGAAGTCGGCGAGC
GCCCCGAGGTCATGGAGTGCTACTTGATGACGGGCGACGCCGACTATCTGCTGCGCGTCGTCGTGCCCGACATGCAGGGG
CTCGAACGCTTCATCGTGCAGTGGCTCACGAAGATTCCGGGCGTATCGAATATCCGCTCCAGCTTCGCGCTGAAGCAGGT
GCGCTACAAGACGGCGTTGCCGCTGCCCGTCGCGGGTCTTACGCTCGCCGCGCAAGACGACGCGCCGCGCGAATGGGCCT
GA

Upstream 100 bases:

>100_bases
GCAACAACGGGGCGGGCACCGCTCGATAAATCCGTCATGGCGCAACTCCGGCAGAAAGCGTGGGTGAAAGGCGACTCGAA
AAGGTCTCATCAGCTTACCC

Downstream 100 bases:

>100_bases
TCTGGGCCCTGCTCGCACGCAGACAGGCGGTTTAGCACGGCGCAGGCGTTACGCGGTCGCGCAGTTCGCGGCGAATGACC
TTGCCCGTCGCCGTCATCGG

Product: AsnC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 213; Mature: 213

Protein sequence:

>213_residues
MRPENVRLFCLRRRFHIVYLFWYIGFTWNIYTMASDARHAAAARRLDRIDIAILQQLQQNARITNAELARAVNLSPTPCF
NRVRALERLGLFRQQVTLLDAEALGLRINVFIQVSLEKQVEEALRRFEQEVGERPEVMECYLMTGDADYLLRVVVPDMQG
LERFIVQWLTKIPGVSNIRSSFALKQVRYKTALPLPVAGLTLAAQDDAPREWA

Sequences:

>Translated_213_residues
MRPENVRLFCLRRRFHIVYLFWYIGFTWNIYTMASDARHAAAARRLDRIDIAILQQLQQNARITNAELARAVNLSPTPCF
NRVRALERLGLFRQQVTLLDAEALGLRINVFIQVSLEKQVEEALRRFEQEVGERPEVMECYLMTGDADYLLRVVVPDMQG
LERFIVQWLTKIPGVSNIRSSFALKQVRYKTALPLPVAGLTLAAQDDAPREWA
>Mature_213_residues
MRPENVRLFCLRRRFHIVYLFWYIGFTWNIYTMASDARHAAAARRLDRIDIAILQQLQQNARITNAELARAVNLSPTPCF
NRVRALERLGLFRQQVTLLDAEALGLRINVFIQVSLEKQVEEALRRFEQEVGERPEVMECYLMTGDADYLLRVVVPDMQG
LERFIVQWLTKIPGVSNIRSSFALKQVRYKTALPLPVAGLTLAAQDDAPREWA

Specific function: Positive regulator of the bkd operon for branched-chain keto acid dehydrogenase complex [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081742, Length=150, Percent_Identity=40, Blast_Score=121, Evalue=3e-29,
Organism=Escherichia coli, GI1787116, Length=151, Percent_Identity=37.7483443708609, Blast_Score=120, Evalue=5e-29,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg [H]

EC number: NA

Molecular weight: Translated: 24633; Mature: 24633

Theoretical pI: Translated: 9.49; Mature: 9.49

Prosite motif: PS00519 HTH_ASNC_1 ; PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPENVRLFCLRRRFHIVYLFWYIGFTWNIYTMASDARHAAAARRLDRIDIAILQQLQQN
CCCCCEEHEEHHHHHHHHHHHHHHHHHEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHC
ARITNAELARAVNLSPTPCFNRVRALERLGLFRQQVTLLDAEALGLRINVFIQVSLEKQV
CCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEEEEEHHHHH
EEALRRFEQEVGERPEVMECYLMTGDADYLLRVVVPDMQGLERFIVQWLTKIPGVSNIRS
HHHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHH
SFALKQVRYKTALPLPVAGLTLAAQDDAPREWA
HHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCC
>Mature Secondary Structure
MRPENVRLFCLRRRFHIVYLFWYIGFTWNIYTMASDARHAAAARRLDRIDIAILQQLQQN
CCCCCEEHEEHHHHHHHHHHHHHHHHHEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHC
ARITNAELARAVNLSPTPCFNRVRALERLGLFRQQVTLLDAEALGLRINVFIQVSLEKQV
CCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEEEEEHHHHH
EEALRRFEQEVGERPEVMECYLMTGDADYLLRVVVPDMQGLERFIVQWLTKIPGVSNIRS
HHHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHH
SFALKQVRYKTALPLPVAGLTLAAQDDAPREWA
HHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8320210 [H]