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The map label for this gene is cfxR [H]

Identifier: 186476584

GI number: 186476584

Start: 2087348

End: 2088301

Strand: Reverse

Name: cfxR [H]

Synonym: Bphy_1827

Alternate gene names: 186476584

Gene position: 2088301-2087348 (Counterclockwise)

Preceding gene: 186476586

Following gene: 186476582

Centisome position: 60.02

GC content: 63.42

Gene sequence:

>954_bases
ATGTTAAAAGCCGCGACGTTCCGGCAATTGAAGGCGCTCCATACGGTGGCGAAGCTGGGCAGCGTATCGGGTGCGGCGGA
GGAGTTGCGTCTGACGCAGCCTGCCGTGTCGCTGCAGATCCGCTTGCTCGAAGAAGCGGCTGGCGCGCCGCTTCTGCAAC
GCGTGGGGCGCGGCGTGCAACTGACCGCGGCGGGCGAAATCCTCGCGCGTTATGCGCTGGAAATCCTCGACCTGTGGAAT
GGCGCCGCAGACGATCTCGCGGCGTTGCACGGCGAGCAGGGCGGCACGCTGCGCATCGGTGCGATTACGACGGCCGAATA
TCTGATCCCGCCGTTTCTCGTGCGCTTCACAGAAGCGCGTCCGCAGGTGAAGGTGCAGTTCAAGGTGGGCAACCGCGCGG
ACATCATCCGCATGCTCGCGACGCATGAAATCGATCTCGCCGTGATGGGCAGTCCGCCGCGCGAATTGCGCACGGTCGCC
ACGGTGTTCGCCAAGCATCCGATGGCATTTGTCGCGTCGCCGTCGCATGCGCTGATGAAAAAGAGGCGGCTCTCATTCGG
CGATTTGCAGTCGGCAAACCTCTTCGTGCGCGAGCGCGGCTCGGGCACGCGGTCGACCGTCGAAAACCTCTTCAAGCAGG
CGGGCCACAAGATCCATATCGGCTCCGAGTTGTCGAGTAACGAGGCGATCAAGCAACTGGTGGAAGCGGGGCTCGGCATA
TCGTTCCTGTCGCTGCACGCGTGCACGCTGGAGTTTCAGGCGGGTCTGCTGGCGTTGCTGCCGCTGCCGGACAACCCGAT
CGAGCGCGACTGGTACGTGATGCATGTATCGGACAAGCGGCTGCCGCAGGTCGCCAGTCTGTTTCGTGACTTTCTGATCG
AACAGGGCATCAAAGGCAGCGTGCCGATCCCGATGCCATCCGTCGCGGCCGCAAAGAAACGCCGGCACGTGTGA

Upstream 100 bases:

>100_bases
ATGCGATTCATGCGTGAACATCATCAGTAAGGTCGAGTATAGAATTGGGGGAAACCGCAGCACAATTTAATGTTTGTACA
AGACATATAGGTTTTCACTT

Downstream 100 bases:

>100_bases
AATCTGCCGGTTCCTTTCGGCGGCGGGTATCGTCAATCGGGAAACGGACGCGAGTACGGCGAGTTCGGTCTCGAAGATTG
TCTCGCGATCGAGGCGTGGC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: RuBisCO operon transcriptional regulator [H]

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MLKAATFRQLKALHTVAKLGSVSGAAEELRLTQPAVSLQIRLLEEAAGAPLLQRVGRGVQLTAAGEILARYALEILDLWN
GAADDLAALHGEQGGTLRIGAITTAEYLIPPFLVRFTEARPQVKVQFKVGNRADIIRMLATHEIDLAVMGSPPRELRTVA
TVFAKHPMAFVASPSHALMKKRRLSFGDLQSANLFVRERGSGTRSTVENLFKQAGHKIHIGSELSSNEAIKQLVEAGLGI
SFLSLHACTLEFQAGLLALLPLPDNPIERDWYVMHVSDKRLPQVASLFRDFLIEQGIKGSVPIPMPSVAAAKKRRHV

Sequences:

>Translated_317_residues
MLKAATFRQLKALHTVAKLGSVSGAAEELRLTQPAVSLQIRLLEEAAGAPLLQRVGRGVQLTAAGEILARYALEILDLWN
GAADDLAALHGEQGGTLRIGAITTAEYLIPPFLVRFTEARPQVKVQFKVGNRADIIRMLATHEIDLAVMGSPPRELRTVA
TVFAKHPMAFVASPSHALMKKRRLSFGDLQSANLFVRERGSGTRSTVENLFKQAGHKIHIGSELSSNEAIKQLVEAGLGI
SFLSLHACTLEFQAGLLALLPLPDNPIERDWYVMHVSDKRLPQVASLFRDFLIEQGIKGSVPIPMPSVAAAKKRRHV
>Mature_317_residues
MLKAATFRQLKALHTVAKLGSVSGAAEELRLTQPAVSLQIRLLEEAAGAPLLQRVGRGVQLTAAGEILARYALEILDLWN
GAADDLAALHGEQGGTLRIGAITTAEYLIPPFLVRFTEARPQVKVQFKVGNRADIIRMLATHEIDLAVMGSPPRELRTVA
TVFAKHPMAFVASPSHALMKKRRLSFGDLQSANLFVRERGSGTRSTVENLFKQAGHKIHIGSELSSNEAIKQLVEAGLGI
SFLSLHACTLEFQAGLLALLPLPDNPIERDWYVMHVSDKRLPQVASLFRDFLIEQGIKGSVPIPMPSVAAAKKRRHV

Specific function: Trans-acting transcriptional regulator of RuBisCO genes (cfxLS) expression [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788481, Length=287, Percent_Identity=30.3135888501742, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI157672245, Length=231, Percent_Identity=29.8701298701299, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1787601, Length=141, Percent_Identity=35.4609929078014, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI87081904, Length=273, Percent_Identity=28.2051282051282, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI145693105, Length=235, Percent_Identity=25.9574468085106, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1788748, Length=294, Percent_Identity=26.1904761904762, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787530, Length=231, Percent_Identity=27.2727272727273, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1787879, Length=241, Percent_Identity=27.8008298755187, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI87082132, Length=260, Percent_Identity=26.1538461538462, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1790399, Length=240, Percent_Identity=25, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1786401, Length=294, Percent_Identity=27.2108843537415, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI1789440, Length=241, Percent_Identity=26.1410788381743, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790208, Length=243, Percent_Identity=27.1604938271605, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790262, Length=240, Percent_Identity=30, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788626, Length=258, Percent_Identity=27.906976744186, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI48994962, Length=189, Percent_Identity=28.042328042328, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788887, Length=262, Percent_Identity=26.7175572519084, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788297, Length=252, Percent_Identity=25.7936507936508, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34534; Mature: 34534

Theoretical pI: Translated: 10.46; Mature: 10.46

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKAATFRQLKALHTVAKLGSVSGAAEELRLTQPAVSLQIRLLEEAAGAPLLQRVGRGVQ
CCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHCCCEE
LTAAGEILARYALEILDLWNGAADDLAALHGEQGGTLRIGAITTAEYLIPPFLVRFTEAR
EEHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCEEEEEEECHHHHHHHHHHHHHHCCC
PQVKVQFKVGNRADIIRMLATHEIDLAVMGSPPRELRTVATVFAKHPMAFVASPSHALMK
CCEEEEEEECCHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHCCEEEEECCHHHHHH
KRRLSFGDLQSANLFVRERGSGTRSTVENLFKQAGHKIHIGSELSSNEAIKQLVEAGLGI
HHCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHCCCH
SFLSLHACTLEFQAGLLALLPLPDNPIERDWYVMHVSDKRLPQVASLFRDFLIEQGIKGS
HHHHHHHHHHHHCCCEEEEEECCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCC
VPIPMPSVAAAKKRRHV
CCCCCCHHHHHHHHCCC
>Mature Secondary Structure
MLKAATFRQLKALHTVAKLGSVSGAAEELRLTQPAVSLQIRLLEEAAGAPLLQRVGRGVQ
CCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHCCCEE
LTAAGEILARYALEILDLWNGAADDLAALHGEQGGTLRIGAITTAEYLIPPFLVRFTEAR
EEHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCEEEEEEECHHHHHHHHHHHHHHCCC
PQVKVQFKVGNRADIIRMLATHEIDLAVMGSPPRELRTVATVFAKHPMAFVASPSHALMK
CCEEEEEEECCHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHCCEEEEECCHHHHHH
KRRLSFGDLQSANLFVRERGSGTRSTVENLFKQAGHKIHIGSELSSNEAIKQLVEAGLGI
HHCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHCCCH
SFLSLHACTLEFQAGLLALLPLPDNPIERDWYVMHVSDKRLPQVASLFRDFLIEQGIKGS
HHHHHHHHHHHHCCCEEEEEECCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCC
VPIPMPSVAAAKKRRHV
CCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1779759 [H]