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The map label for this gene is dgdR [H]

Identifier: 186476564

GI number: 186476564

Start: 2065150

End: 2066004

Strand: Direct

Name: dgdR [H]

Synonym: Bphy_1806

Alternate gene names: 186476564

Gene position: 2065150-2066004 (Clockwise)

Preceding gene: 186476561

Following gene: 186476574

Centisome position: 59.36

GC content: 66.43

Gene sequence:

>855_bases
ATGAAAGCTCTCGATCTCGATGTGCTCGCGATGTTCGTCGCCATTGCGGATACGGGCAGCTTCGTGCGCGGCGCGACGCT
CGTGCATCGTTCGCAATCGGCGCTGAGCATGCAGATCCGCTCGCTCGAAACCGCCATCGGCAAGGCGCTGTTCGTGCGTG
GGCCGCGCAGCGTCACGCTCACGCAGGAGGGCCAGGTGCTGCTCAGCTACGCGCGCCGCATGCTCGCGTTGCGCGACGAA
GCGTGGGCGTCCATCGTGCATCCGGAAGTGACGGGCCGCGTCGCGATCGGCGTGCCGGACGACTACGCGTCGTCCCTCTT
GCCGTCCGTGCTGCGCGACTTCTCGGCGACGTATCCGAAGGTCGAGATCCAGGTGGTGAGCCTGCCGAGCAATGCGCTCG
CGCCGCTCCTGAAGGACAACAAGATCGACCTCGCGTGCGTGACGCGCGTGAAGGGCCTCGCGGGAGAATTCATCCGGCTC
GAACCGATGGTGTGGGCGGGCACCTCCGCCGCAGGGCGCGAAGTGTGGAAAGAGCGCCCGCTTCCCATCGCGCTGTTCGG
CATCGGCAGCGTCGCGCGCGCCAACGCGATTCAAACGCTGGAGCGCGCGAAGATCGCGTATCGCACGTCGTATGAAAGTC
CGAGTCTGATGGGTCTCTTGAGCATGGTCGAAGCGGGCCTCGCCGTCGCGCCGCTGGCGCGCTGCGCGGTGCCCGACCGC
TTCGTCACACTGGGGCGTCAGCATGGGCTGCCGAAACTGCCGGAACTGGAAATTATCCTTGCGCGCAGCGCGCGCTCGAA
CCGGCCGCCGTGCGACTATCTGGCCGAGCAGATTCTCAGCGAACTGCGCGATTGA

Upstream 100 bases:

>100_bases
TGTGTGAACCGAGTATGCCGCCGCCCCTGAGTTCAGACAAACGCGTTATATTGAACATTTCGATCAATAATCCTGATGGC
ACTGGGGAGGATGCAAGCGG

Downstream 100 bases:

>100_bases
TCACGCCGGCGCGGCGCGCTGCATTCAGCTCTCTTCGCCTCTCTCTTCGCCCAGTTGCACGAGCAACGCATGCAGCCGTT
CCGTATGACGCAACAGCATG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: 2,2-dialkylglycine decarboxylase repressor [H]

Number of amino acids: Translated: 284; Mature: 284

Protein sequence:

>284_residues
MKALDLDVLAMFVAIADTGSFVRGATLVHRSQSALSMQIRSLETAIGKALFVRGPRSVTLTQEGQVLLSYARRMLALRDE
AWASIVHPEVTGRVAIGVPDDYASSLLPSVLRDFSATYPKVEIQVVSLPSNALAPLLKDNKIDLACVTRVKGLAGEFIRL
EPMVWAGTSAAGREVWKERPLPIALFGIGSVARANAIQTLERAKIAYRTSYESPSLMGLLSMVEAGLAVAPLARCAVPDR
FVTLGRQHGLPKLPELEIILARSARSNRPPCDYLAEQILSELRD

Sequences:

>Translated_284_residues
MKALDLDVLAMFVAIADTGSFVRGATLVHRSQSALSMQIRSLETAIGKALFVRGPRSVTLTQEGQVLLSYARRMLALRDE
AWASIVHPEVTGRVAIGVPDDYASSLLPSVLRDFSATYPKVEIQVVSLPSNALAPLLKDNKIDLACVTRVKGLAGEFIRL
EPMVWAGTSAAGREVWKERPLPIALFGIGSVARANAIQTLERAKIAYRTSYESPSLMGLLSMVEAGLAVAPLARCAVPDR
FVTLGRQHGLPKLPELEIILARSARSNRPPCDYLAEQILSELRD
>Mature_284_residues
MKALDLDVLAMFVAIADTGSFVRGATLVHRSQSALSMQIRSLETAIGKALFVRGPRSVTLTQEGQVLLSYARRMLALRDE
AWASIVHPEVTGRVAIGVPDDYASSLLPSVLRDFSATYPKVEIQVVSLPSNALAPLLKDNKIDLACVTRVKGLAGEFIRL
EPMVWAGTSAAGREVWKERPLPIALFGIGSVARANAIQTLERAKIAYRTSYESPSLMGLLSMVEAGLAVAPLARCAVPDR
FVTLGRQHGLPKLPELEIILARSARSNRPPCDYLAEQILSELRD

Specific function: Not Known, Does Not Seem To Act On The Proton Translocating NADH Dehydrogenase Genes (Nuoa-N) Which Are Part Of The Lrha Operon. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788626, Length=267, Percent_Identity=35.9550561797753, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1787806, Length=250, Percent_Identity=28, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI157672245, Length=135, Percent_Identity=34.0740740740741, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1788297, Length=171, Percent_Identity=29.2397660818713, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1790399, Length=249, Percent_Identity=29.3172690763052, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1790208, Length=126, Percent_Identity=36.5079365079365, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI2367136, Length=121, Percent_Identity=33.8842975206612, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI145693105, Length=246, Percent_Identity=26.0162601626016, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1790262, Length=160, Percent_Identity=27.5, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1788887, Length=145, Percent_Identity=33.1034482758621, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1787589, Length=127, Percent_Identity=33.8582677165354, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 30828; Mature: 30828

Theoretical pI: Translated: 9.43; Mature: 9.43

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKALDLDVLAMFVAIADTGSFVRGATLVHRSQSALSMQIRSLETAIGKALFVRGPRSVTL
CCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCEEEE
TQEGQVLLSYARRMLALRDEAWASIVHPEVTGRVAIGVPDDYASSLLPSVLRDFSATYPK
ECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCE
VEIQVVSLPSNALAPLLKDNKIDLACVTRVKGLAGEFIRLEPMVWAGTSAAGREVWKERP
EEEEEEECCCHHHHHHHCCCCCCHHHHHHHHHHCCCEEEECCEEEECCCHHHHHHHHCCC
LPIALFGIGSVARANAIQTLERAKIAYRTSYESPSLMGLLSMVEAGLAVAPLARCAVPDR
CCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHCCCHH
FVTLGRQHGLPKLPELEIILARSARSNRPPCDYLAEQILSELRD
HHHHHHHCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MKALDLDVLAMFVAIADTGSFVRGATLVHRSQSALSMQIRSLETAIGKALFVRGPRSVTL
CCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCEEEE
TQEGQVLLSYARRMLALRDEAWASIVHPEVTGRVAIGVPDDYASSLLPSVLRDFSATYPK
ECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCE
VEIQVVSLPSNALAPLLKDNKIDLACVTRVKGLAGEFIRLEPMVWAGTSAAGREVWKERP
EEEEEEECCCHHHHHHHCCCCCCHHHHHHHHHHCCCEEEECCEEEECCCHHHHHHHHCCC
LPIALFGIGSVARANAIQTLERAKIAYRTSYESPSLMGLLSMVEAGLAVAPLARCAVPDR
CCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHCCCHH
FVTLGRQHGLPKLPELEIILARSARSNRPPCDYLAEQILSELRD
HHHHHHHCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2180928 [H]