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The map label for this gene is cph2 [H]

Identifier: 186476535

GI number: 186476535

Start: 2029702

End: 2031531

Strand: Direct

Name: cph2 [H]

Synonym: Bphy_1777

Alternate gene names: 186476535

Gene position: 2029702-2031531 (Clockwise)

Preceding gene: 186476531

Following gene: 186476536

Centisome position: 58.34

GC content: 65.25

Gene sequence:

>1830_bases
ATGGAAGCGACCAGGATCACCCCAGCCCGCCGGGGCTTGCTGCGCACGGCGATCGACCGATTGCGCGCGGTCCGTCAGCC
CGCACGCGCGACGGTTGCGCCGGGCACGCCAGCCGTCTCGCACGGGCTCGAACAGGCCGCAGGCGCCGTCGACTTCCTCG
CGCATGTAGCTCACAATCTCACCTTTCTATATGTCTCCGACGCGAGCCTGCGCTTTATCGGCTACCACCGGGAATATCTG
CAAACGGTCACGCTGCACGAACTCGTCGCGCCAGGCGACGTAGCGCGGCTGGACGCCGCACTGCGCCGCGCCGACGAAAG
CGGCGCCGTCGAAAAAATCACGCTGGACCTGATCAAGTCGCTGACCTATCCCGTGCCTGTCGAGCTGCGTATCGCGCGCA
ACTGCCACGACGGCATCGAGGGCTACGCGATCGCCGGCTTCGACGTGTCGAGCTGGCGCGCGACAGAAGCGAGCCTCAAA
CATCAGCTGCATCACGACAATCTGACGGGCCTCGCGAACGTGCCCGCCCTCGTCGAGGAAATGCGCCACGCGCAACAGAA
GGCGGATGCAACAGGCAAGTCCGCTGCCCTGCTGCTGCTCGATATCGACGACTACCAGCGCGTGAACCGCGCGCTCGGCT
ACGACGCGGGCGACGAGATGCTGCGCGATACCGCCCGGCGCCTGTCTAACATGACGACGCAAGGCGAAGTGATCGCGCGC
ATCTCCAGCGACGAATTCGCGATCCTGCTGCCACCCGTGCACGCCCGTGCCGACACGGCGTTGGCCGCCGAAGCGCTCGC
GCGGCGTCTATTGACGGCCATCCAGCAGCCGTACACGTTTAACCGGCAGCCAGTCCATCTGTCGGCGAGCGTCGGCATCG
CGCTCTATCCGGACACGCAGCAGGCGGGCGAATCGCCCGATGCGCCGCCGCGCGACAGCCAGCTGCTGCGCTGGGCCGAT
TATGCGCTGTCGCGCGCGAAGGCAGCGGGCGGCAACACGCTCGCGTTCTACATGCCCGACGACAGCCCCGCCGACGCCGA
ACGTCTGAAGCTCGAATCGGACCTGTACGACGGCGTGCGCAACGGCGAGTTTTCGCTGCACTTCCAGCCGATCACGAGCA
GCCAGACCCGCGGCGTGGTCGGCGTCGAGGCGCTGATCCGCTGGCAGCATCCCGTGCACGGGCTCGTGCCGCCGTCGATG
TTCATTCCCCTCGCCGAATCCGTCGGTCTCATCAACTACCTGGGCAACTGGGTGCTGAAGGCCGCGTGCATGCAGCTGAT
CCGCTGGGACACGCAAGGCATCCGGCTGCAATACGTCGCCGTGAATGTGTCGCCGCAGCAGTTCCGCGACCCGCGCTTCA
AGGAAAGCGTGCGCGAAGCGATCGCACTGACGGGCATCGACCCGCACCGGCTCGTGTTCGAGATCACGGAAAGCCTGCTG
ATGCATGACCCGCAGCACGCGACCACGCTGCTCGAAGAACTGACAGGCCTCGGCATCCGCTTCGCCGTCGACGATTTCGG
CACCGGCTATTCGAGCCTTGCGTATCTGCAACGCTTTCCGCTCGCCAAGTTGAAAATCGACCGGAGTTTTGTGGAGAATC
TGCTAACCTCGCGCAACGATCAGGCGATCGTCAGCGCCGTGGTGGGTCTTGCGCAGACGCTCGACCTCGAACTCGTCGCG
GAAGGTGTCGAGACGGAAGCACAACGCGACCTGCTGACCGAGATGGGCTGCGACCACATTCAGGGCTGGCTCGTCTGCAA
GGCACTGCCATCGGAAGAACTCGCGCAGCGTTTCGAATCGCGCGCGCTTCATGTGCATGGTGAAGCGTGA

Upstream 100 bases:

>100_bases
CCGTTCTGATGGACGGCCTCGCGCCTGCCCCGATTCGGCCAGCCGACGGGCGTCGCAGCGGCGTCCAGCCTCAAGACGAA
CCGGGTAGTCAGCGATACAC

Downstream 100 bases:

>100_bases
CCGACTCGACGCGTAGCGAAACCGTAGTGCCACTCACTGGAAACTGTATGCCTCTTGCGGGACTCTCATGCTAAAGGCTG
CGCTGCTTGACCGGCTCTGG

Product: diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: Bacteriophytochrome cph2 [H]

Number of amino acids: Translated: 609; Mature: 609

Protein sequence:

>609_residues
MEATRITPARRGLLRTAIDRLRAVRQPARATVAPGTPAVSHGLEQAAGAVDFLAHVAHNLTFLYVSDASLRFIGYHREYL
QTVTLHELVAPGDVARLDAALRRADESGAVEKITLDLIKSLTYPVPVELRIARNCHDGIEGYAIAGFDVSSWRATEASLK
HQLHHDNLTGLANVPALVEEMRHAQQKADATGKSAALLLLDIDDYQRVNRALGYDAGDEMLRDTARRLSNMTTQGEVIAR
ISSDEFAILLPPVHARADTALAAEALARRLLTAIQQPYTFNRQPVHLSASVGIALYPDTQQAGESPDAPPRDSQLLRWAD
YALSRAKAAGGNTLAFYMPDDSPADAERLKLESDLYDGVRNGEFSLHFQPITSSQTRGVVGVEALIRWQHPVHGLVPPSM
FIPLAESVGLINYLGNWVLKAACMQLIRWDTQGIRLQYVAVNVSPQQFRDPRFKESVREAIALTGIDPHRLVFEITESLL
MHDPQHATTLLEELTGLGIRFAVDDFGTGYSSLAYLQRFPLAKLKIDRSFVENLLTSRNDQAIVSAVVGLAQTLDLELVA
EGVETEAQRDLLTEMGCDHIQGWLVCKALPSEELAQRFESRALHVHGEA

Sequences:

>Translated_609_residues
MEATRITPARRGLLRTAIDRLRAVRQPARATVAPGTPAVSHGLEQAAGAVDFLAHVAHNLTFLYVSDASLRFIGYHREYL
QTVTLHELVAPGDVARLDAALRRADESGAVEKITLDLIKSLTYPVPVELRIARNCHDGIEGYAIAGFDVSSWRATEASLK
HQLHHDNLTGLANVPALVEEMRHAQQKADATGKSAALLLLDIDDYQRVNRALGYDAGDEMLRDTARRLSNMTTQGEVIAR
ISSDEFAILLPPVHARADTALAAEALARRLLTAIQQPYTFNRQPVHLSASVGIALYPDTQQAGESPDAPPRDSQLLRWAD
YALSRAKAAGGNTLAFYMPDDSPADAERLKLESDLYDGVRNGEFSLHFQPITSSQTRGVVGVEALIRWQHPVHGLVPPSM
FIPLAESVGLINYLGNWVLKAACMQLIRWDTQGIRLQYVAVNVSPQQFRDPRFKESVREAIALTGIDPHRLVFEITESLL
MHDPQHATTLLEELTGLGIRFAVDDFGTGYSSLAYLQRFPLAKLKIDRSFVENLLTSRNDQAIVSAVVGLAQTLDLELVA
EGVETEAQRDLLTEMGCDHIQGWLVCKALPSEELAQRFESRALHVHGEA
>Mature_609_residues
MEATRITPARRGLLRTAIDRLRAVRQPARATVAPGTPAVSHGLEQAAGAVDFLAHVAHNLTFLYVSDASLRFIGYHREYL
QTVTLHELVAPGDVARLDAALRRADESGAVEKITLDLIKSLTYPVPVELRIARNCHDGIEGYAIAGFDVSSWRATEASLK
HQLHHDNLTGLANVPALVEEMRHAQQKADATGKSAALLLLDIDDYQRVNRALGYDAGDEMLRDTARRLSNMTTQGEVIAR
ISSDEFAILLPPVHARADTALAAEALARRLLTAIQQPYTFNRQPVHLSASVGIALYPDTQQAGESPDAPPRDSQLLRWAD
YALSRAKAAGGNTLAFYMPDDSPADAERLKLESDLYDGVRNGEFSLHFQPITSSQTRGVVGVEALIRWQHPVHGLVPPSM
FIPLAESVGLINYLGNWVLKAACMQLIRWDTQGIRLQYVAVNVSPQQFRDPRFKESVREAIALTGIDPHRLVFEITESLL
MHDPQHATTLLEELTGLGIRFAVDDFGTGYSSLAYLQRFPLAKLKIDRSFVENLLTSRNDQAIVSAVVGLAQTLDLELVA
EGVETEAQRDLLTEMGCDHIQGWLVCKALPSEELAQRFESRALHVHGEA

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 GGDEF domains [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=462, Percent_Identity=33.7662337662338, Blast_Score=253, Evalue=2e-68,
Organism=Escherichia coli, GI87081921, Length=436, Percent_Identity=33.256880733945, Blast_Score=244, Evalue=1e-65,
Organism=Escherichia coli, GI226510982, Length=456, Percent_Identity=29.8245614035088, Blast_Score=183, Evalue=2e-47,
Organism=Escherichia coli, GI1788502, Length=255, Percent_Identity=34.1176470588235, Blast_Score=146, Evalue=3e-36,
Organism=Escherichia coli, GI1786507, Length=244, Percent_Identity=35.2459016393443, Blast_Score=145, Evalue=8e-36,
Organism=Escherichia coli, GI1790496, Length=238, Percent_Identity=34.0336134453782, Blast_Score=142, Evalue=5e-35,
Organism=Escherichia coli, GI87081743, Length=240, Percent_Identity=33.3333333333333, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1787055, Length=260, Percent_Identity=31.9230769230769, Blast_Score=135, Evalue=1e-32,
Organism=Escherichia coli, GI1788849, Length=244, Percent_Identity=32.7868852459016, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI87081980, Length=255, Percent_Identity=30.5882352941176, Blast_Score=125, Evalue=1e-29,
Organism=Escherichia coli, GI87081845, Length=253, Percent_Identity=30.8300395256917, Blast_Score=114, Evalue=3e-26,
Organism=Escherichia coli, GI87082096, Length=235, Percent_Identity=29.3617021276596, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI1788381, Length=487, Percent_Identity=23.4086242299795, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI87081881, Length=185, Percent_Identity=30.2702702702703, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1787410, Length=246, Percent_Identity=24.7967479674797, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI1786584, Length=168, Percent_Identity=30.3571428571429, Blast_Score=64, Evalue=4e-11,
Organism=Escherichia coli, GI145693134, Length=179, Percent_Identity=26.2569832402235, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR003018
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515 [H]

Pfam domain/function: PF00563 EAL; PF01590 GAF; PF00990 GGDEF; PF00360 Phytochrome [H]

EC number: NA

Molecular weight: Translated: 67058; Mature: 67058

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEATRITPARRGLLRTAIDRLRAVRQPARATVAPGTPAVSHGLEQAAGAVDFLAHVAHNL
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCE
TFLYVSDASLRFIGYHREYLQTVTLHELVAPGDVARLDAALRRADESGAVEKITLDLIKS
EEEEEECCCEEEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHH
LTYPVPVELRIARNCHDGIEGYAIAGFDVSSWRATEASLKHQLHHDNLTGLANVPALVEE
CCCCCCEEEEEECCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHH
MRHAQQKADATGKSAALLLLDIDDYQRVNRALGYDAGDEMLRDTARRLSNMTTQGEVIAR
HHHHHHHHCCCCCCEEEEEEECHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCEEEE
ISSDEFAILLPPVHARADTALAAEALARRLLTAIQQPYTFNRQPVHLSASVGIALYPDTQ
ECCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCEEECCCHH
QAGESPDAPPRDSQLLRWADYALSRAKAAGGNTLAFYMPDDSPADAERLKLESDLYDGVR
HCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCC
NGEFSLHFQPITSSQTRGVVGVEALIRWQHPVHGLVPPSMFIPLAESVGLINYLGNWVLK
CCCEEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
AACMQLIRWDTQGIRLQYVAVNVSPQQFRDPRFKESVREAIALTGIDPHRLVFEITESLL
HHHHHHHHCCCCCEEEEEEEEECCHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
MHDPQHATTLLEELTGLGIRFAVDDFGTGYSSLAYLQRFPLAKLKIDRSFVENLLTSRND
HCCCHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCC
QAIVSAVVGLAQTLDLELVAEGVETEAQRDLLTEMGCDHIQGWLVCKALPSEELAQRFES
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCEEEEECCCHHHHHHHHHH
RALHVHGEA
CEEEEECCC
>Mature Secondary Structure
MEATRITPARRGLLRTAIDRLRAVRQPARATVAPGTPAVSHGLEQAAGAVDFLAHVAHNL
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCE
TFLYVSDASLRFIGYHREYLQTVTLHELVAPGDVARLDAALRRADESGAVEKITLDLIKS
EEEEEECCCEEEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHH
LTYPVPVELRIARNCHDGIEGYAIAGFDVSSWRATEASLKHQLHHDNLTGLANVPALVEE
CCCCCCEEEEEECCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHH
MRHAQQKADATGKSAALLLLDIDDYQRVNRALGYDAGDEMLRDTARRLSNMTTQGEVIAR
HHHHHHHHCCCCCCEEEEEEECHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCEEEE
ISSDEFAILLPPVHARADTALAAEALARRLLTAIQQPYTFNRQPVHLSASVGIALYPDTQ
ECCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCEEECCCHH
QAGESPDAPPRDSQLLRWADYALSRAKAAGGNTLAFYMPDDSPADAERLKLESDLYDGVR
HCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCC
NGEFSLHFQPITSSQTRGVVGVEALIRWQHPVHGLVPPSMFIPLAESVGLINYLGNWVLK
CCCEEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
AACMQLIRWDTQGIRLQYVAVNVSPQQFRDPRFKESVREAIALTGIDPHRLVFEITESLL
HHHHHHHHCCCCCEEEEEEEEECCHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
MHDPQHATTLLEELTGLGIRFAVDDFGTGYSSLAYLQRFPLAKLKIDRSFVENLLTSRND
HCCCHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCC
QAIVSAVVGLAQTLDLELVAEGVETEAQRDLLTEMGCDHIQGWLVCKALPSEELAQRFES
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCEEEEECCCHHHHHHHHHH
RALHVHGEA
CEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 10978170; 11063585 [H]