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The map label for this gene is hfq [H]

Identifier: 186476469

GI number: 186476469

Start: 1951214

End: 1951666

Strand: Direct

Name: hfq [H]

Synonym: Bphy_1711

Alternate gene names: 186476469

Gene position: 1951214-1951666 (Clockwise)

Preceding gene: 186476462

Following gene: 186476471

Centisome position: 56.08

GC content: 65.34

Gene sequence:

>453_bases
ATGCCTTCCGCAGAATCGCATCCGCAAAACGACTTTATGAACGCAGCGCGCAAAGAACGTAAGCGCGTCGAGATTTATCT
CGTCAACGGCATCCGCCTGACGGGCTGCATCGAGTCGTTCGATCAGTATCTGGTGATGCTGCGTACGCCCGTCGGGCTGC
AAGGCATCTACAAGCGCGCCATTTCGACGATCCAGCTCGATACGGGCTCGCGGCCCGCGCCCCGCGCAGGCCGGCCGTCG
CACGGCGACCATTCCGCACGCGGGCCGCATGGTTCGCGCGAACATCGCGAGCCGCGCGAACCTCGTGAGTCGTACGGCGG
GTCGCAAGGTTCGTCGGACCGTTCGTCGTCTTCGTCGTCGGACGGACCTGTGGTCGTCACGCGCCGCCGGCGCCTGTATG
GCGCGGGCAACGGCAACGACCAGGGCAACAACGGCGGCGGCCACGGCGAATAA

Upstream 100 bases:

>100_bases
TGAGCATCAACCGGTTCGGCGTTAGGAGCCCATCATGTCGGCACAGGGCGACAACGGGTAAAATCGCGCTGAACAACCGT
TTCTCTATACACAATTGTCC

Downstream 100 bases:

>100_bases
ACATGGCTGCACCGGGCGCGCTGCCGGCGCGCCCGTCCTCCCGTCATACGGGCAGACTGGCTAAGCGCGGCGATCCGCCA
ACTGCTTCAGCATCCTGTCG

Product: RNA chaperone Hfq

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 150; Mature: 149

Protein sequence:

>150_residues
MPSAESHPQNDFMNAARKERKRVEIYLVNGIRLTGCIESFDQYLVMLRTPVGLQGIYKRAISTIQLDTGSRPAPRAGRPS
HGDHSARGPHGSREHREPREPRESYGGSQGSSDRSSSSSSDGPVVVTRRRRLYGAGNGNDQGNNGGGHGE

Sequences:

>Translated_150_residues
MPSAESHPQNDFMNAARKERKRVEIYLVNGIRLTGCIESFDQYLVMLRTPVGLQGIYKRAISTIQLDTGSRPAPRAGRPS
HGDHSARGPHGSREHREPREPRESYGGSQGSSDRSSSSSSDGPVVVTRRRRLYGAGNGNDQGNNGGGHGE
>Mature_149_residues
PSAESHPQNDFMNAARKERKRVEIYLVNGIRLTGCIESFDQYLVMLRTPVGLQGIYKRAISTIQLDTGSRPAPRAGRPSH
GDHSARGPHGSREHREPREPRESYGGSQGSSDRSSSSSSDGPVVVTRRRRLYGAGNGNDQGNNGGGHGE

Specific function: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs [H]

COG id: COG1923

COG function: function code R; Uncharacterized host factor I protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hfq family [H]

Homologues:

Organism=Escherichia coli, GI1790614, Length=84, Percent_Identity=47.6190476190476, Blast_Score=73, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005001
- InterPro:   IPR010920
- InterPro:   IPR001163 [H]

Pfam domain/function: PF01423 LSM [H]

EC number: NA

Molecular weight: Translated: 16311; Mature: 16180

Theoretical pI: Translated: 10.33; Mature: 10.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSAESHPQNDFMNAARKERKRVEIYLVNGIRLTGCIESFDQYLVMLRTPVGLQGIYKRA
CCCCCCCCCHHHHHHHHHHHHEEEEEEECCEEHHHHHHHHHHHHHHHHCCCCHHHHHHHH
ISTIQLDTGSRPAPRAGRPSHGDHSARGPHGSREHREPREPRESYGGSQGSSDRSSSSSS
HHEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCC
DGPVVVTRRRRLYGAGNGNDQGNNGGGHGE
CCCEEEEECCEEEECCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PSAESHPQNDFMNAARKERKRVEIYLVNGIRLTGCIESFDQYLVMLRTPVGLQGIYKRA
CCCCCCCCHHHHHHHHHHHHEEEEEEECCEEHHHHHHHHHHHHHHHHCCCCHHHHHHHH
ISTIQLDTGSRPAPRAGRPSHGDHSARGPHGSREHREPREPRESYGGSQGSSDRSSSSSS
HHEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCC
DGPVVVTRRRRLYGAGNGNDQGNNGGGHGE
CCCEEEEECCEEEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA