Click here to switch to the map view.

The map label for this gene is fabG [H]

Identifier: 186476459

GI number: 186476459

Start: 1940675

End: 1942090

Strand: Direct

Name: fabG [H]

Synonym: Bphy_1701

Alternate gene names: 186476459

Gene position: 1940675-1942090 (Clockwise)

Preceding gene: 186476458

Following gene: 186476460

Centisome position: 55.78

GC content: 69.63

Gene sequence:

>1416_bases
ATGAACGATTCCTACCTGAACTTCGTCAATTCGCCGCTGGGCGCGCGGCTCGCGCGCTCGCTCGGTTTGCCGAAGCCCGA
GGTGCTGCGCCGCTACCGTGCCGACGCGCCCGAATTCGACGGCATCGTCGCCGTCGGCGCAGGTCCCTCGCCTCAGTTGC
TGGACGCCTTCGCCGACGTCGTCGCGCATACCGGCATGACGAGCGTCGCCCATTCGGGCGCAGGCCTTTGGGTGCCGCTC
GCCAACCGGCACGGACTGATGACGGGCCGCTTCGAGCCCGCGGAGCGCACGGGCGGATCGCAGGCGCGCGTGCGGGCGCT
CGTGTTCGACGCAAGCGGCATCGACGCCAGCGCGCAGCTCGATTCGCTCTATCGCTTCTTTCACGACGCGCTGCGCTCGC
TCGACGCGTGTGGCCGGATCGTCGTGCTCGGCCGTCCGCCCGAGTCGCGTGCGACGCCGCTTGCATGGACGGCGCAGCGC
GCGCTCGAAGGCGTGACGCGCTCGCTCGGCAAGGAAGCGCGGCGCGGCATCGCGGCCAATCTGATCTACGTGGCGCAAGG
CGCGGAAGCGGGCATCGAAGCGACGCTGCGCTTCTTCCTTTCGCCGCGCTCGGCCTACGTGTCGGGCCAGGTCGTGCGGA
TCGGCACCGCCCCCTTCACACCCGCGCCGGACTTTGACTGGACCCGACCGCTCGCGGGCCAGCGCGCCGTCGTGACGGGC
GCGGCGCGCGGCATCGGGGCGGCCATTGCGAACGTGCTCGCGGCGCATGGGGCGCACGTGATCGGCATCGACATTCCGTC
GGCCGGCGATGCGCTCGACACGACGATGCGCCAGATCGGCGGCACCGCGCTCGCGTTCGACATCGGCGCACCCGACACGC
CCGCGCAAATCGCGGCCGCGCTCGACGAACTCGGTGTCGACGTGTTCGTGCACAACGCAGGCATCACGAAGGACAAGACC
ATCGCGAAGATGAGCGAGGCGGCATGGCGCGATGTGATCGACATCAATCTGTCCGCGCAGGAGCGCATCGACGACGCGCT
GCTTGAAGCGGGCACGCTGCGCAACGGCGGGCGCATCGTGTCGGTGTCGTCGATCAGCGGCATCGCGGGCAATGTCGGCC
AGACCCACTACGCGGCGTCGAAAGCGGGCGTGATCGGGCGCGTGCAAAGCATGGCGCCGTTTCTCGCGCAACGACACATC
ACGATCAACGCCGTCGCGCCCGGTTTCATCGAAACGCAGATGACGGCGAAGATGCCGCTGGCGCTGCGCGAAGCCGGCCG
CCGGATGAATTCGATGAGCCAGGGCGGCCAGCCCGCCGACGTCGCGCAGACGGTCGCATGGCTTGCGCATCCAGGCTCGG
CGGGCGTGACGGGCCAGCTCGTGCGCGTGTGCGGACAAAGCCTGATAGGAGCGTGA

Upstream 100 bases:

>100_bases
GCCAACCGCATCGGCCGGAACGGGGACGCGGGCACAGCTTGCGGCAAGTCGCGCGCTCCGTGCACACTGACGCCATGCGT
CCGGCCGGGAGCCAATACGA

Downstream 100 bases:

>100_bases
GGCCATGGCGTTCTACGACTCCAGCTCGATGTTCGGCGCGCCGCGTCAGAAAACCGTCGTGCTGCCCGAACTGCCCAAGC
CCGCCAGGCTCTACGCACGG

Product: 3-ketoacyl-(acyl-carrier-protein) reductase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 471; Mature: 471

Protein sequence:

>471_residues
MNDSYLNFVNSPLGARLARSLGLPKPEVLRRYRADAPEFDGIVAVGAGPSPQLLDAFADVVAHTGMTSVAHSGAGLWVPL
ANRHGLMTGRFEPAERTGGSQARVRALVFDASGIDASAQLDSLYRFFHDALRSLDACGRIVVLGRPPESRATPLAWTAQR
ALEGVTRSLGKEARRGIAANLIYVAQGAEAGIEATLRFFLSPRSAYVSGQVVRIGTAPFTPAPDFDWTRPLAGQRAVVTG
AARGIGAAIANVLAAHGAHVIGIDIPSAGDALDTTMRQIGGTALAFDIGAPDTPAQIAAALDELGVDVFVHNAGITKDKT
IAKMSEAAWRDVIDINLSAQERIDDALLEAGTLRNGGRIVSVSSISGIAGNVGQTHYAASKAGVIGRVQSMAPFLAQRHI
TINAVAPGFIETQMTAKMPLALREAGRRMNSMSQGGQPADVAQTVAWLAHPGSAGVTGQLVRVCGQSLIGA

Sequences:

>Translated_471_residues
MNDSYLNFVNSPLGARLARSLGLPKPEVLRRYRADAPEFDGIVAVGAGPSPQLLDAFADVVAHTGMTSVAHSGAGLWVPL
ANRHGLMTGRFEPAERTGGSQARVRALVFDASGIDASAQLDSLYRFFHDALRSLDACGRIVVLGRPPESRATPLAWTAQR
ALEGVTRSLGKEARRGIAANLIYVAQGAEAGIEATLRFFLSPRSAYVSGQVVRIGTAPFTPAPDFDWTRPLAGQRAVVTG
AARGIGAAIANVLAAHGAHVIGIDIPSAGDALDTTMRQIGGTALAFDIGAPDTPAQIAAALDELGVDVFVHNAGITKDKT
IAKMSEAAWRDVIDINLSAQERIDDALLEAGTLRNGGRIVSVSSISGIAGNVGQTHYAASKAGVIGRVQSMAPFLAQRHI
TINAVAPGFIETQMTAKMPLALREAGRRMNSMSQGGQPADVAQTVAWLAHPGSAGVTGQLVRVCGQSLIGA
>Mature_471_residues
MNDSYLNFVNSPLGARLARSLGLPKPEVLRRYRADAPEFDGIVAVGAGPSPQLLDAFADVVAHTGMTSVAHSGAGLWVPL
ANRHGLMTGRFEPAERTGGSQARVRALVFDASGIDASAQLDSLYRFFHDALRSLDACGRIVVLGRPPESRATPLAWTAQR
ALEGVTRSLGKEARRGIAANLIYVAQGAEAGIEATLRFFLSPRSAYVSGQVVRIGTAPFTPAPDFDWTRPLAGQRAVVTG
AARGIGAAIANVLAAHGAHVIGIDIPSAGDALDTTMRQIGGTALAFDIGAPDTPAQIAAALDELGVDVFVHNAGITKDKT
IAKMSEAAWRDVIDINLSAQERIDDALLEAGTLRNGGRIVSVSSISGIAGNVGQTHYAASKAGVIGRVQSMAPFLAQRHI
TINAVAPGFIETQMTAKMPLALREAGRRMNSMSQGGQPADVAQTVAWLAHPGSAGVTGQLVRVCGQSLIGA

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI15277342, Length=248, Percent_Identity=39.9193548387097, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI4504505, Length=229, Percent_Identity=32.3144104803493, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI32483357, Length=246, Percent_Identity=30.4878048780488, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI40254992, Length=238, Percent_Identity=31.0924369747899, Blast_Score=86, Evalue=9e-17,
Organism=Homo sapiens, GI5031737, Length=248, Percent_Identity=30.6451612903226, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI20149619, Length=243, Percent_Identity=29.2181069958848, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI19923817, Length=255, Percent_Identity=28.6274509803922, Blast_Score=73, Evalue=7e-13,
Organism=Homo sapiens, GI109715829, Length=226, Percent_Identity=27.8761061946903, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI10190704, Length=243, Percent_Identity=28.3950617283951, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI33667109, Length=194, Percent_Identity=32.9896907216495, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI126723750, Length=283, Percent_Identity=25.7950530035336, Blast_Score=70, Evalue=6e-12,
Organism=Homo sapiens, GI7657478, Length=152, Percent_Identity=32.8947368421053, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI4758504, Length=258, Percent_Identity=28.2945736434109, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1787335, Length=245, Percent_Identity=40.4081632653061, Blast_Score=149, Evalue=4e-37,
Organism=Escherichia coli, GI87082100, Length=244, Percent_Identity=31.9672131147541, Blast_Score=102, Evalue=7e-23,
Organism=Escherichia coli, GI1789208, Length=243, Percent_Identity=29.6296296296296, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1790717, Length=249, Percent_Identity=29.3172690763052, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI87082160, Length=252, Percent_Identity=30.1587301587302, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1787905, Length=241, Percent_Identity=30.7053941908714, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI2367365, Length=238, Percent_Identity=31.9327731092437, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI2367175, Length=249, Percent_Identity=30.9236947791165, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1789057, Length=260, Percent_Identity=28.8461538461538, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788459, Length=246, Percent_Identity=26.8292682926829, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1786812, Length=253, Percent_Identity=24.901185770751, Blast_Score=63, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI25147288, Length=240, Percent_Identity=38.75, Blast_Score=144, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI17555706, Length=242, Percent_Identity=39.2561983471074, Blast_Score=137, Evalue=9e-33,
Organism=Caenorhabditis elegans, GI17568967, Length=206, Percent_Identity=30.0970873786408, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17561402, Length=250, Percent_Identity=27.6, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17508895, Length=206, Percent_Identity=28.6407766990291, Blast_Score=75, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17560676, Length=251, Percent_Identity=28.2868525896414, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17564282, Length=205, Percent_Identity=29.2682926829268, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71994604, Length=250, Percent_Identity=26, Blast_Score=65, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=248, Percent_Identity=29.4354838709677, Blast_Score=96, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24639444, Length=244, Percent_Identity=35.2459016393443, Blast_Score=119, Evalue=6e-27,
Organism=Drosophila melanogaster, GI18859837, Length=229, Percent_Identity=32.3144104803493, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI23397609, Length=246, Percent_Identity=30.4878048780488, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI17737361, Length=248, Percent_Identity=29.0322580645161, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21357041, Length=238, Percent_Identity=30.2521008403361, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24643142, Length=190, Percent_Identity=31.5789473684211, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24644339, Length=240, Percent_Identity=29.5833333333333, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24649181, Length=195, Percent_Identity=27.1794871794872, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 49080; Mature: 49080

Theoretical pI: Translated: 9.09; Mature: 9.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDSYLNFVNSPLGARLARSLGLPKPEVLRRYRADAPEFDGIVAVGAGPSPQLLDAFADV
CCCCHHHHHCCCHHHHHHHHHCCCCHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHH
VAHTGMTSVAHSGAGLWVPLANRHGLMTGRFEPAERTGGSQARVRALVFDASGIDASAQL
HHHCCHHHHHCCCCCEEEEECCCCCCEECCCCCHHHCCCCHHEEEEEEEECCCCCHHHHH
DSLYRFFHDALRSLDACGRIVVLGRPPESRATPLAWTAQRALEGVTRSLGKEARRGIAAN
HHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHE
LIYVAQGAEAGIEATLRFFLSPRSAYVSGQVVRIGTAPFTPAPDFDWTRPLAGQRAVVTG
EEEEECCCCCCHHHHHHHHHCCCHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCEEEEH
AARGIGAAIANVLAAHGAHVIGIDIPSAGDALDTTMRQIGGTALAFDIGAPDTPAQIAAA
HHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHCCEEEEEECCCCCCHHHHHHH
LDELGVDVFVHNAGITKDKTIAKMSEAAWRDVIDINLSAQERIDDALLEAGTLRNGGRIV
HHHCCCEEEEECCCCCCCHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHCCCCCCCEEE
SVSSISGIAGNVGQTHYAASKAGVIGRVQSMAPFLAQRHITINAVAPGFIETQMTAKMPL
EEECCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHCCH
ALREAGRRMNSMSQGGQPADVAQTVAWLAHPGSAGVTGQLVRVCGQSLIGA
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNDSYLNFVNSPLGARLARSLGLPKPEVLRRYRADAPEFDGIVAVGAGPSPQLLDAFADV
CCCCHHHHHCCCHHHHHHHHHCCCCHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHH
VAHTGMTSVAHSGAGLWVPLANRHGLMTGRFEPAERTGGSQARVRALVFDASGIDASAQL
HHHCCHHHHHCCCCCEEEEECCCCCCEECCCCCHHHCCCCHHEEEEEEEECCCCCHHHHH
DSLYRFFHDALRSLDACGRIVVLGRPPESRATPLAWTAQRALEGVTRSLGKEARRGIAAN
HHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHE
LIYVAQGAEAGIEATLRFFLSPRSAYVSGQVVRIGTAPFTPAPDFDWTRPLAGQRAVVTG
EEEEECCCCCCHHHHHHHHHCCCHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCEEEEH
AARGIGAAIANVLAAHGAHVIGIDIPSAGDALDTTMRQIGGTALAFDIGAPDTPAQIAAA
HHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHCCEEEEEECCCCCCHHHHHHH
LDELGVDVFVHNAGITKDKTIAKMSEAAWRDVIDINLSAQERIDDALLEAGTLRNGGRIV
HHHCCCEEEEECCCCCCCHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHCCCCCCCEEE
SVSSISGIAGNVGQTHYAASKAGVIGRVQSMAPFLAQRHITINAVAPGFIETQMTAKMPL
EEECCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHCCH
ALREAGRRMNSMSQGGQPADVAQTVAWLAHPGSAGVTGQLVRVCGQSLIGA
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]