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The map label for this gene is hetI [H]

Identifier: 186476429

GI number: 186476429

Start: 1885242

End: 1885952

Strand: Direct

Name: hetI [H]

Synonym: Bphy_1671

Alternate gene names: 186476429

Gene position: 1885242-1885952 (Clockwise)

Preceding gene: 186476428

Following gene: 186476430

Centisome position: 54.19

GC content: 62.45

Gene sequence:

>711_bases
ATGTCTTCTTCTCTCCTGAGTCCGCCCTTTGCGCAAGAAGTCCATGTCTGGCAGTGGGATCTCGAAGCCTGTGATGACGA
TATCGCGTGCTACTGGGACACGCTCTGCGCACAGGAGCGCGAGCGCGCCGGCAAATTCCGCTTCGACCTGCATCGGCGCC
GGTTCGTCGCGGGACGCGGCGAACTCAGACGGGTCCTTGGCCGTTACCTCGGCATGTCGCCGTCGGATGTCGCGATCGGC
TATGGTCCGCAAGGCAAACCTTGTTGCACCAGCCAGCCTCATGACTGGATGCTCTGCTTCAATCTCAGTCACAGCGAGAG
TACGGCGGCCCTCGCGATATCGAACGGTTTCGAAATCGGCATCGACGTGGAGCGCATCCGGGCGATCGAAGAAATCCTGC
CACTAGAAGTGTTTTCACGGCAGGAACGAGCCGACTACGCTGCCGTGCCCAAAGCACAACAACAAACAGTTTTCTTCGAA
AGCTGGGCGCGCAAAGAGGCATGCCTGAAAGCGCTCGGCACCGGCTTCATGCTGCCGCCCACCCATTTCGAGTTCGACCT
GTCCGTGCCTGGCGACACGGCGCCGCGCCTGGTCGGTGGCGATGCGCGAGAAGCGGCTCATTGGCGCATTCGCCCGCTGT
CGTCCGTTGCGGGCTGCACGGGCGCGGTCGCGGCGCGGCGCACGGACTGGTCGATCGTCGAGATGCGTTGA

Upstream 100 bases:

>100_bases
TGTCGACGGTCGCGTCGTCGCTCGATACACGTTGCGGCTGCAACATCATCGCGATGTCGGGTTGCAAATCTGATTCAATT
CGCGTTGTGTGTTAGCCGCC

Downstream 100 bases:

>100_bases
CACCCGGCATGGGAGCGTCGAACTGCACGACAGCACGCACCCGCCACACAAGCAGCCAAAAACCGACAATAACGTCGCGG
CACTTTGCGCAGACGGCAAC

Product: 4'-phosphopantetheinyl transferase

Products: adenosine 3',5'-bisphosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 236; Mature: 235

Protein sequence:

>236_residues
MSSSLLSPPFAQEVHVWQWDLEACDDDIACYWDTLCAQERERAGKFRFDLHRRRFVAGRGELRRVLGRYLGMSPSDVAIG
YGPQGKPCCTSQPHDWMLCFNLSHSESTAALAISNGFEIGIDVERIRAIEEILPLEVFSRQERADYAAVPKAQQQTVFFE
SWARKEACLKALGTGFMLPPTHFEFDLSVPGDTAPRLVGGDAREAAHWRIRPLSSVAGCTGAVAARRTDWSIVEMR

Sequences:

>Translated_236_residues
MSSSLLSPPFAQEVHVWQWDLEACDDDIACYWDTLCAQERERAGKFRFDLHRRRFVAGRGELRRVLGRYLGMSPSDVAIG
YGPQGKPCCTSQPHDWMLCFNLSHSESTAALAISNGFEIGIDVERIRAIEEILPLEVFSRQERADYAAVPKAQQQTVFFE
SWARKEACLKALGTGFMLPPTHFEFDLSVPGDTAPRLVGGDAREAAHWRIRPLSSVAGCTGAVAARRTDWSIVEMR
>Mature_235_residues
SSSLLSPPFAQEVHVWQWDLEACDDDIACYWDTLCAQERERAGKFRFDLHRRRFVAGRGELRRVLGRYLGMSPSDVAIGY
GPQGKPCCTSQPHDWMLCFNLSHSESTAALAISNGFEIGIDVERIRAIEEILPLEVFSRQERADYAAVPKAQQQTVFFES
WARKEACLKALGTGFMLPPTHFEFDLSVPGDTAPRLVGGDAREAAHWRIRPLSSVAGCTGAVAARRTDWSIVEMR

Specific function: Probably activates the acyl carrier protein (ACP) domain of hetM, by transferring the 4'-phosphopantetheinyl moiety of coenzyme A (CoA) to a serine residue. May be required for maintaining vegetative growth and probably acts via hetN to inhibit differenti

COG id: COG2091

COG function: function code H; Phosphopantetheinyl transferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. Gsp/sfp/hetI/acpT family [H]

Homologues:

Organism=Escherichia coli, GI1789886, Length=124, Percent_Identity=41.1290322580645, Blast_Score=64, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008278 [H]

Pfam domain/function: PF01648 ACPS [H]

EC number: NA

Molecular weight: Translated: 26449; Mature: 26318

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSSLLSPPFAQEVHVWQWDLEACDDDIACYWDTLCAQERERAGKFRFDLHRRRFVAGRG
CCCCCCCCCCCCCEEEEEEEHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHH
ELRRVLGRYLGMSPSDVAIGYGPQGKPCCTSQPHDWMLCFNLSHSESTAALAISNGFEIG
HHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCEEEEEECCCCCCCEEEEECCCCEEC
IDVERIRAIEEILPLEVFSRQERADYAAVPKAQQQTVFFESWARKEACLKALGTGFMLPP
CCHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
THFEFDLSVPGDTAPRLVGGDAREAAHWRIRPLSSVAGCTGAVAARRTDWSIVEMR
CCEEEEEECCCCCCCCEECCCCCCCCEEEEEEHHHHCCCHHHHHHCCCCCEEEEEC
>Mature Secondary Structure 
SSSLLSPPFAQEVHVWQWDLEACDDDIACYWDTLCAQERERAGKFRFDLHRRRFVAGRG
CCCCCCCCCCCCEEEEEEEHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHH
ELRRVLGRYLGMSPSDVAIGYGPQGKPCCTSQPHDWMLCFNLSHSESTAALAISNGFEIG
HHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCEEEEEECCCCCCCEEEEECCCCEEC
IDVERIRAIEEILPLEVFSRQERADYAAVPKAQQQTVFFESWARKEACLKALGTGFMLPP
CCHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
THFEFDLSVPGDTAPRLVGGDAREAAHWRIRPLSSVAGCTGAVAARRTDWSIVEMR
CCEEEEEECCCCCCCCEECCCCCCCCEEEEEEHHHHCCCHHHHHHCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Coenzyme A; apo-[acyl carrier protein] [C]

Specific reaction: Coenzyme A + apo-[acyl carrier protein] = adenosine 3',5'-bisphosphate + [acyl carrier protein] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8157596; 11759840; 8939709 [H]