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The map label for this gene is dgoR [H]

Identifier: 186476425

GI number: 186476425

Start: 1881923

End: 1882669

Strand: Reverse

Name: dgoR [H]

Synonym: Bphy_1667

Alternate gene names: 186476425

Gene position: 1882669-1881923 (Counterclockwise)

Preceding gene: 186476434

Following gene: 186476424

Centisome position: 54.11

GC content: 65.06

Gene sequence:

>747_bases
ATGATGGAACACACCAACAAAGAGCGGTCCCTGGTCAGCAAGGTCATGGATGGCCTCGTGACCGGGATCGTCGAAGAAAA
GTACGGCGCGGTCTTGCCGCCGCAGGACGTATTGTCGAAGGAATTCGACGTCAGCCGCACGGTGATGCGCGAGGCGCTGT
CGATGCTGCTCGCGCGGCACATGCTGGACGTGCGGCCCAAGATCGGCACGCGCATCCGGCCGATGCACGACTGGCGCATG
ATCGACGAGGACGTCGTGAACTGGCGCTTCCGCGCGAAGCCCGATCCGACGTTCCTGCGCGACGTGATCGAGTTCCGCGT
GCTGATCGAACCGCGTGCGGCTGCGCAGGCTGCGACGCGCGGCAACGCTTCGGACATCGCTGCGATCCGCGATGCGTTCG
AGGCTTTCCGCAACAGTCCGCCAGGCGAGCCCGGTCATCAGACTGCGGATGAAGCGCTGCATACGCGCATCGTGATCGCA
AGCGGCAACCAGTTCTTCCAGCAGATGGCGGCGATCATTCGCGGCGCGCTGCAGGCACTGAAGCCGCTCGTCGATCTGCC
CACGGGCGCATGGGAGGAAACGGTGCGCCTGCATTCGCGGGTCGTCGACGCGATCGAGCGGCACGATGCGAAAGAAGCGG
AAGCGGGGTCGATTGCGCTGATCGATTTCTCGATGAGCCGCATGAGCGCAGCGGTGTCCGATCTGCCCGCAACGCCTGCC
GCTCCCGCGGCACCGGCGGAGCAATAG

Upstream 100 bases:

>100_bases
GAGATAAAGCGAAGCAACGTAATGTTCGCAAATAAGAAATGACACGAGGGCACGTGATCAACATTCATCGCAGGCGAGAA
CCGCCGCATCGGGGAGAAGG

Downstream 100 bases:

>100_bases
GACGAAGCAGCAGGTTTCAATACGGCATCGGTTGACCGTGGGAAGGCCTGTCCGGCGAGTGGATACGCGACATCGGCGAC
AATGTCGGTTGTCACTCACT

Product: GntR domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MMEHTNKERSLVSKVMDGLVTGIVEEKYGAVLPPQDVLSKEFDVSRTVMREALSMLLARHMLDVRPKIGTRIRPMHDWRM
IDEDVVNWRFRAKPDPTFLRDVIEFRVLIEPRAAAQAATRGNASDIAAIRDAFEAFRNSPPGEPGHQTADEALHTRIVIA
SGNQFFQQMAAIIRGALQALKPLVDLPTGAWEETVRLHSRVVDAIERHDAKEAEAGSIALIDFSMSRMSAAVSDLPATPA
APAAPAEQ

Sequences:

>Translated_248_residues
MMEHTNKERSLVSKVMDGLVTGIVEEKYGAVLPPQDVLSKEFDVSRTVMREALSMLLARHMLDVRPKIGTRIRPMHDWRM
IDEDVVNWRFRAKPDPTFLRDVIEFRVLIEPRAAAQAATRGNASDIAAIRDAFEAFRNSPPGEPGHQTADEALHTRIVIA
SGNQFFQQMAAIIRGALQALKPLVDLPTGAWEETVRLHSRVVDAIERHDAKEAEAGSIALIDFSMSRMSAAVSDLPATPA
APAAPAEQ
>Mature_248_residues
MMEHTNKERSLVSKVMDGLVTGIVEEKYGAVLPPQDVLSKEFDVSRTVMREALSMLLARHMLDVRPKIGTRIRPMHDWRM
IDEDVVNWRFRAKPDPTFLRDVIEFRVLIEPRAAAQAATRGNASDIAAIRDAFEAFRNSPPGEPGHQTADEALHTRIVIA
SGNQFFQQMAAIIRGALQALKPLVDLPTGAWEETVRLHSRVVDAIERHDAKEAEAGSIALIDFSMSRMSAAVSDLPATPA
APAAPAEQ

Specific function: Repressor for the dgoRKAT operon. Binds D-galactonate as an inducer [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI48994955, Length=218, Percent_Identity=27.5229357798165, Blast_Score=87, Evalue=8e-19,
Organism=Escherichia coli, GI48994961, Length=226, Percent_Identity=27.8761061946903, Blast_Score=84, Evalue=7e-18,
Organism=Escherichia coli, GI1790032, Length=231, Percent_Identity=28.1385281385281, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 27424; Mature: 27424

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMEHTNKERSLVSKVMDGLVTGIVEEKYGAVLPPQDVLSKEFDVSRTVMREALSMLLARH
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
MLDVRPKIGTRIRPMHDWRMIDEDVVNWRFRAKPDPTFLRDVIEFRVLIEPRAAAQAATR
HHHCCCCCCCCCCCHHHHHHHHHHHHCCEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHC
GNASDIAAIRDAFEAFRNSPPGEPGHQTADEALHTRIVIASGNQFFQQMAAIIRGALQAL
CCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHHHH
KPLVDLPTGAWEETVRLHSRVVDAIERHDAKEAEAGSIALIDFSMSRMSAAVSDLPATPA
HHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHCCCCCC
APAAPAEQ
CCCCCCCC
>Mature Secondary Structure
MMEHTNKERSLVSKVMDGLVTGIVEEKYGAVLPPQDVLSKEFDVSRTVMREALSMLLARH
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
MLDVRPKIGTRIRPMHDWRMIDEDVVNWRFRAKPDPTFLRDVIEFRVLIEPRAAAQAATR
HHHCCCCCCCCCCCHHHHHHHHHHHHCCEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHC
GNASDIAAIRDAFEAFRNSPPGEPGHQTADEALHTRIVIASGNQFFQQMAAIIRGALQAL
CCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHHHH
KPLVDLPTGAWEETVRLHSRVVDAIERHDAKEAEAGSIALIDFSMSRMSAAVSDLPATPA
HHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHCCCCCC
APAAPAEQ
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503 [H]