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The map label for this gene is fusC [H]

Identifier: 186476341

GI number: 186476341

Start: 1792636

End: 1794870

Strand: Direct

Name: fusC [H]

Synonym: Bphy_1583

Alternate gene names: 186476341

Gene position: 1792636-1794870 (Clockwise)

Preceding gene: 186476340

Following gene: 186476342

Centisome position: 51.52

GC content: 67.56

Gene sequence:

>2235_bases
ATGTCCACGAACTCTCCCGCCTTCCGCACGCCGACGACGCCGACGCCGCGCGCGTTCTACGCCGCCTTGCTCGACTGGGC
GCGCACCGATGGCCGCACCTGGATCTATCTGCTCAAGGCGCTCGCCGCATGCTTTCTTGCGCTGGGCGTCGCGATGAAGC
TCGACCTGCCGCAGCCGCGCACCGCGATGACGACCGTGTTCATCGTGATGCAGCCGCAGAGCGGCATGGTGTTCGCGAAG
AGCTTTTACCGGATCTGCGGGACGCTGATCGGCCTCGTCGTGATGATGGCGCTGATCGGTCTGTTTTCGCAGCAGCCCGA
GCTGTTCATCATCTCGACGGCGATCTGGGTTGGCATTTGCACAGCGGGCGCCGCGCGCAACCGCAATTTCCGCTCGTATG
GCTTCGTGCTGGCGGGCTACACGGCCGCGCTGATCGGCATCCCCGCCTCGCAGCATCCCGACGGCGCGTTCATGACGGCG
CTCACGCGGGTCGCGGAAGTCGTGGTCGGCATTCTGTGCTCGGGCGCGGTGAGCGCGCTCGTGTTTCCGCAGCACGCGGG
CGAGCAGATGCGCAGCACCGTGCGGGCGCGCTTCTCGTCGTTCGTCGACTATGTGCGCGCGGCGCTCTCGGGCGAGGTGG
ATCGCGCGCGCATCGAGGACACCAACGCGAAGTTCGTCGCCGATGTGGTCGGCTTCGAGGCGGTGCGCAGCGTCGCCGCG
TTCGACAGCCCGGACTCGCGGATGCGCAACGGCCGGCTGTCGCGTCTGAATAGCGAGTTCATGACGGTATCGACGCGCTT
TCACGCGCTGCATCAGTTGATGAACCGCCTGCGCGTATCGGACACGGCGGGCGCGACGGCAGCCGTCGACGCGCTCGTAC
CGTATTTCCGCGAGATTTCGCCGTTGCTGAGCAAGTCGGGCGAGCCCGTGCTGACGGCCGCCGACGCTGCGCATGCGGCG
GCGCAGCTTGAAGCGTTCAAGGCCGACTTGCCGAGGCGCGTGTGCGCGACGCGCAAGGTACTCGAGCGTCGCGCTGACGC
GCCGCTGCTCGACTTCGACACAGGCGCCGAACTGCTTTACCGCTTCGTCGACGATCTGCACGCGTATGCCGCGACCTACG
CGTCGCTCGCGGTCGCGACGCACGAGCGCGAACGCTGGATTGCGCGCTACCAGCCGAAGACGAACGGCATCGCGGCGGGT
GTCGCGGGCTTGCGCGCGGCGATCGTGATGACGATCCTCGGCGCGTTCTGGATCGCGACTGCATGGCCGAGCGGCTCGAC
ACTGACGTTGAACGCGGCCGCCGTGTGCGCGCTTGCCTCGTCGTCGCCGAATCCGACGCGCACCGCATCGCAAATGGCAG
CGGGCACGATCCTGTCATCGGCGCTCGCCATGTGCCTGACGTTCGGCATCTACCCGCATATCGATGGCTTTGCGCTGCTG
TGCGCCGCGCTCACGCCGTTCCTCGCGCTCGGCGTGTGGTTGACGACGCGCCCGAAGTTAGCGGGGTACGGCGTCGGCTA
CTGCATCTTCTTCTGCTTCCTCGCGGGTCCGGACAACCTGATTCGCTACGACCCGAGCAGCTTCATCAACGACGCGATGG
CGCTCGTGCTCTCGATGCTGGTTGCGTCGATCGCATTCGCCGTGCTGTTGCCGCCGTCGACGCCGTGGCTGCGCAACCGG
CTGTTGGCCGATCTTCGCGCGCAGGTGGTGCTGGCGTGCCGCGGCCGCATTGGACGGCTATGGCGGCTGCGCACGCGCTT
CGAGAGCGGCGCGCGCGACCTGATGCATCAGATCAACGCGCTGGCAGCGAGCGAAGCCGAGGTGAGGCGCGAGACCATGC
GCTGGACGTTCGCGGTGCTGGAGGTCGGCAATGCCGTGATCGATCTGCGCAGCGAAGTCGCGACGCTGCCGCGCGATGCG
CGCTATGCGCCGTCGATGGCGTGGCGCGTCGGTCTGCGTGCGACCTGTTCGGCCGTGAGCCGTCTGTTCGAGCGGCCGCG
CGCCGAGCGTCTCGACGCTGCGCTTGCTGCGACGGCCGACGCGATCGCCGCCGTTCAGCAGACGCTCGCGACGTTCACGC
CGCCGCGCGACGAGCGTCACCAGTTGCAACGCATTTTGAGTCATCTGCATTTCATCCGGAGCGCGCTGCTCGATCCGCAA
TCGCCGTTGGGGCAACTCGGCGGTGCTGGCGGCACGAACAGCGACACGCCACAAGGAGTTCGCCATGCCACGTGA

Upstream 100 bases:

>100_bases
ATGTGCTGCCCGCGCACGGCAAGGGCAAGGGCTCGAAAGCGGACGCCTCTGCGACCGCTTCGACGGGCGCGCCCGCCGCT
CATTGACAGGAGGGCAGCCG

Downstream 100 bases:

>100_bases
GATTGCCGTTCTCGACGCGTACGTTCCCGCCATCGTGCTGCTGTTTATCGCGGGCACCGCGATCACCTGGGTGCTCGACC
GCGCGATGGCCTGGACGGGC

Product: fusaric acid resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 744; Mature: 743

Protein sequence:

>744_residues
MSTNSPAFRTPTTPTPRAFYAALLDWARTDGRTWIYLLKALAACFLALGVAMKLDLPQPRTAMTTVFIVMQPQSGMVFAK
SFYRICGTLIGLVVMMALIGLFSQQPELFIISTAIWVGICTAGAARNRNFRSYGFVLAGYTAALIGIPASQHPDGAFMTA
LTRVAEVVVGILCSGAVSALVFPQHAGEQMRSTVRARFSSFVDYVRAALSGEVDRARIEDTNAKFVADVVGFEAVRSVAA
FDSPDSRMRNGRLSRLNSEFMTVSTRFHALHQLMNRLRVSDTAGATAAVDALVPYFREISPLLSKSGEPVLTAADAAHAA
AQLEAFKADLPRRVCATRKVLERRADAPLLDFDTGAELLYRFVDDLHAYAATYASLAVATHERERWIARYQPKTNGIAAG
VAGLRAAIVMTILGAFWIATAWPSGSTLTLNAAAVCALASSSPNPTRTASQMAAGTILSSALAMCLTFGIYPHIDGFALL
CAALTPFLALGVWLTTRPKLAGYGVGYCIFFCFLAGPDNLIRYDPSSFINDAMALVLSMLVASIAFAVLLPPSTPWLRNR
LLADLRAQVVLACRGRIGRLWRLRTRFESGARDLMHQINALAASEAEVRRETMRWTFAVLEVGNAVIDLRSEVATLPRDA
RYAPSMAWRVGLRATCSAVSRLFERPRAERLDAALAATADAIAAVQQTLATFTPPRDERHQLQRILSHLHFIRSALLDPQ
SPLGQLGGAGGTNSDTPQGVRHAT

Sequences:

>Translated_744_residues
MSTNSPAFRTPTTPTPRAFYAALLDWARTDGRTWIYLLKALAACFLALGVAMKLDLPQPRTAMTTVFIVMQPQSGMVFAK
SFYRICGTLIGLVVMMALIGLFSQQPELFIISTAIWVGICTAGAARNRNFRSYGFVLAGYTAALIGIPASQHPDGAFMTA
LTRVAEVVVGILCSGAVSALVFPQHAGEQMRSTVRARFSSFVDYVRAALSGEVDRARIEDTNAKFVADVVGFEAVRSVAA
FDSPDSRMRNGRLSRLNSEFMTVSTRFHALHQLMNRLRVSDTAGATAAVDALVPYFREISPLLSKSGEPVLTAADAAHAA
AQLEAFKADLPRRVCATRKVLERRADAPLLDFDTGAELLYRFVDDLHAYAATYASLAVATHERERWIARYQPKTNGIAAG
VAGLRAAIVMTILGAFWIATAWPSGSTLTLNAAAVCALASSSPNPTRTASQMAAGTILSSALAMCLTFGIYPHIDGFALL
CAALTPFLALGVWLTTRPKLAGYGVGYCIFFCFLAGPDNLIRYDPSSFINDAMALVLSMLVASIAFAVLLPPSTPWLRNR
LLADLRAQVVLACRGRIGRLWRLRTRFESGARDLMHQINALAASEAEVRRETMRWTFAVLEVGNAVIDLRSEVATLPRDA
RYAPSMAWRVGLRATCSAVSRLFERPRAERLDAALAATADAIAAVQQTLATFTPPRDERHQLQRILSHLHFIRSALLDPQ
SPLGQLGGAGGTNSDTPQGVRHAT
>Mature_743_residues
STNSPAFRTPTTPTPRAFYAALLDWARTDGRTWIYLLKALAACFLALGVAMKLDLPQPRTAMTTVFIVMQPQSGMVFAKS
FYRICGTLIGLVVMMALIGLFSQQPELFIISTAIWVGICTAGAARNRNFRSYGFVLAGYTAALIGIPASQHPDGAFMTAL
TRVAEVVVGILCSGAVSALVFPQHAGEQMRSTVRARFSSFVDYVRAALSGEVDRARIEDTNAKFVADVVGFEAVRSVAAF
DSPDSRMRNGRLSRLNSEFMTVSTRFHALHQLMNRLRVSDTAGATAAVDALVPYFREISPLLSKSGEPVLTAADAAHAAA
QLEAFKADLPRRVCATRKVLERRADAPLLDFDTGAELLYRFVDDLHAYAATYASLAVATHERERWIARYQPKTNGIAAGV
AGLRAAIVMTILGAFWIATAWPSGSTLTLNAAAVCALASSSPNPTRTASQMAAGTILSSALAMCLTFGIYPHIDGFALLC
AALTPFLALGVWLTTRPKLAGYGVGYCIFFCFLAGPDNLIRYDPSSFINDAMALVLSMLVASIAFAVLLPPSTPWLRNRL
LADLRAQVVLACRGRIGRLWRLRTRFESGARDLMHQINALAASEAEVRRETMRWTFAVLEVGNAVIDLRSEVATLPRDAR
YAPSMAWRVGLRATCSAVSRLFERPRAERLDAALAATADAIAAVQQTLATFTPPRDERHQLQRILSHLHFIRSALLDPQS
PLGQLGGAGGTNSDTPQGVRHAT

Specific function: Involved in the resistance (detoxification) of the fungal toxin fusaric acid [H]

COG id: COG1289

COG function: function code S; Predicted membrane protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aromatic acid exporter ArAE (TC 2.A.85) family [H]

Homologues:

Organism=Escherichia coli, GI1787933, Length=625, Percent_Identity=26.56, Blast_Score=140, Evalue=3e-34,
Organism=Escherichia coli, GI1789636, Length=539, Percent_Identity=25.7884972170686, Blast_Score=102, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006726 [H]

Pfam domain/function: PF04632 FUSC [H]

EC number: NA

Molecular weight: Translated: 80552; Mature: 80421

Theoretical pI: Translated: 9.83; Mature: 9.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTNSPAFRTPTTPTPRAFYAALLDWARTDGRTWIYLLKALAACFLALGVAMKLDLPQPR
CCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHEECCCCCC
TAMTTVFIVMQPQSGMVFAKSFYRICGTLIGLVVMMALIGLFSQQPELFIISTAIWVGIC
CEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHH
TAGAARNRNFRSYGFVLAGYTAALIGIPASQHPDGAFMTALTRVAEVVVGILCSGAVSAL
HCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VFPQHAGEQMRSTVRARFSSFVDYVRAALSGEVDRARIEDTNAKFVADVVGFEAVRSVAA
HCCHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHH
FDSPDSRMRNGRLSRLNSEFMTVSTRFHALHQLMNRLRVSDTAGATAAVDALVPYFREIS
CCCCHHHHHCCHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
PLLSKSGEPVLTAADAAHAAAQLEAFKADLPRRVCATRKVLERRADAPLLDFDTGAELLY
HHHHCCCCCEEEECHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCEECCCHHHHHH
RFVDDLHAYAATYASLAVATHERERWIARYQPKTNGIAAGVAGLRAAIVMTILGAFWIAT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AWPSGSTLTLNAAAVCALASSSPNPTRTASQMAAGTILSSALAMCLTFGIYPHIDGFALL
CCCCCCEEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
CAALTPFLALGVWLTTRPKLAGYGVGYCIFFCFLAGPDNLIRYDPSSFINDAMALVLSML
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHH
VASIAFAVLLPPSTPWLRNRLLADLRAQVVLACRGRIGRLWRLRTRFESGARDLMHQINA
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAASEAEVRRETMRWTFAVLEVGNAVIDLRSEVATLPRDARYAPSMAWRVGLRATCSAVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
RLFERPRAERLDAALAATADAIAAVQQTLATFTPPRDERHQLQRILSHLHFIRSALLDPQ
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
SPLGQLGGAGGTNSDTPQGVRHAT
CCHHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
STNSPAFRTPTTPTPRAFYAALLDWARTDGRTWIYLLKALAACFLALGVAMKLDLPQPR
CCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHEECCCCCC
TAMTTVFIVMQPQSGMVFAKSFYRICGTLIGLVVMMALIGLFSQQPELFIISTAIWVGIC
CEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHH
TAGAARNRNFRSYGFVLAGYTAALIGIPASQHPDGAFMTALTRVAEVVVGILCSGAVSAL
HCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VFPQHAGEQMRSTVRARFSSFVDYVRAALSGEVDRARIEDTNAKFVADVVGFEAVRSVAA
HCCHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHH
FDSPDSRMRNGRLSRLNSEFMTVSTRFHALHQLMNRLRVSDTAGATAAVDALVPYFREIS
CCCCHHHHHCCHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
PLLSKSGEPVLTAADAAHAAAQLEAFKADLPRRVCATRKVLERRADAPLLDFDTGAELLY
HHHHCCCCCEEEECHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCEECCCHHHHHH
RFVDDLHAYAATYASLAVATHERERWIARYQPKTNGIAAGVAGLRAAIVMTILGAFWIAT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AWPSGSTLTLNAAAVCALASSSPNPTRTASQMAAGTILSSALAMCLTFGIYPHIDGFALL
CCCCCCEEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
CAALTPFLALGVWLTTRPKLAGYGVGYCIFFCFLAGPDNLIRYDPSSFINDAMALVLSML
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHH
VASIAFAVLLPPSTPWLRNRLLADLRAQVVLACRGRIGRLWRLRTRFESGARDLMHQINA
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAASEAEVRRETMRWTFAVLEVGNAVIDLRSEVATLPRDARYAPSMAWRVGLRATCSAVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
RLFERPRAERLDAALAATADAIAAVQQTLATFTPPRDERHQLQRILSHLHFIRSALLDPQ
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
SPLGQLGGAGGTNSDTPQGVRHAT
CCHHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1370369 [H]