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The map label for this gene is aroC

Identifier: 186476327

GI number: 186476327

Start: 1777762

End: 1778862

Strand: Reverse

Name: aroC

Synonym: Bphy_1569

Alternate gene names: 186476327

Gene position: 1778862-1777762 (Counterclockwise)

Preceding gene: 186476328

Following gene: 186476326

Centisome position: 51.13

GC content: 66.49

Gene sequence:

>1101_bases
ATGTCCGGCAATACCCTCGGTACGCTCTTCACCGTCACGACCTTCGGCGAATCGCACGGCCCGGCTATCGGCTGTGTAAT
CGACGGCTGCCCACCGGGTATGTCGCTCGCCGAAGCCGACATCCAGCTTGAACTCGACCGCCGCAAGCCGGGCACGTCGC
GCCATGTGACGCAGCGCCAGGAAGAAGACAAGGTCGAGATTCTCTCCGGCGTCTTCGAGGGCAAGACGACGGGCGCGCCG
ATTGCACTGCTGATCCGCAATACGGACCAGCGCAGCAAGGACTACGGCAATATCGCCGACACGTTCCGCCCCGGCCACGC
CGACTACACCTACTGGCAGAAATTCGGCATACGCGACTATCGCGGCGGCGGCCGTTCGTCCGCGCGCCTGACGGCGCCGA
CGGTGGCAGCGGGCGCAGTCGCGAAGAAGTGGCTGCGCGAGAAGTTCGGCACGGAGATTCGCGGCTACATGGCGGCGCTC
GGCGAGATCGACGTGCCGTTCATCGACTGGCAGTTCGTGCGCGAGAACCCGTTCTTCGTGCCGAACGCGGATGTCGTGCC
GCAACTCGAAGCGTACATGGACGCGTTGCGCAAGGACGGCGATTCGATCGGCGCGCGCATCAACGTGGTTGCGTCGGGCG
TGCCCGTCGGACTTGGTGAGCCGCTGTTCGACCGCCTCGACGCCGACATCGCGCATGCAATGATGGGCATCAACGCGGTG
AAGGGCGTCGAAATCGGCGCGGGATTCGCGAGCGTGGCGCAGCGCGGCTCCGTGCATGGTGACGAGCTGACGCCGGAAGG
CTTCGTCGGCAATCACGCGGGCGGCGTGCTCGGCGGTATTTCGACGGGGCAGGACATCACGGTCTCGATCGCGATCAAGC
CGACGTCGAGCATCCGCACGCCGCGCCGCTCGATCGACAAGAACGGGCAGCCCGCCGTCGTCGAAACGTTCGGCCGCCAC
GACCCCTGTGTCGGCATTCGTGCCACGCCGATCGCCGAAGCCATGCTCGCCCTCGTGCTGATCGACCATGCGTTGCGGCA
CCGCGCGCAATGCGGCGACGTGGTGGTCGGTACGCCGAAGATCGCCGCCAGCGCGCCGTAA

Upstream 100 bases:

>100_bases
GTCCATTTGTCCTATCCCACTGGACGGACCGCTGCGCGCTACGGCAGCGCGTCGGGACTGGCATAATATCGCTCTCCCCG
CATTTCTTTGGACGACGCTC

Downstream 100 bases:

>100_bases
CGCCGGCTCGATCCGGCAGGCTTGACGGTTTCTGACGGGCGTCAACATGCGCGATAACGATCTCACAATGGCCGACCCGC
TCGAGCCCCTGCGGGCGCGT

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase

Number of amino acids: Translated: 366; Mature: 365

Protein sequence:

>366_residues
MSGNTLGTLFTVTTFGESHGPAIGCVIDGCPPGMSLAEADIQLELDRRKPGTSRHVTQRQEEDKVEILSGVFEGKTTGAP
IALLIRNTDQRSKDYGNIADTFRPGHADYTYWQKFGIRDYRGGGRSSARLTAPTVAAGAVAKKWLREKFGTEIRGYMAAL
GEIDVPFIDWQFVRENPFFVPNADVVPQLEAYMDALRKDGDSIGARINVVASGVPVGLGEPLFDRLDADIAHAMMGINAV
KGVEIGAGFASVAQRGSVHGDELTPEGFVGNHAGGVLGGISTGQDITVSIAIKPTSSIRTPRRSIDKNGQPAVVETFGRH
DPCVGIRATPIAEAMLALVLIDHALRHRAQCGDVVVGTPKIAASAP

Sequences:

>Translated_366_residues
MSGNTLGTLFTVTTFGESHGPAIGCVIDGCPPGMSLAEADIQLELDRRKPGTSRHVTQRQEEDKVEILSGVFEGKTTGAP
IALLIRNTDQRSKDYGNIADTFRPGHADYTYWQKFGIRDYRGGGRSSARLTAPTVAAGAVAKKWLREKFGTEIRGYMAAL
GEIDVPFIDWQFVRENPFFVPNADVVPQLEAYMDALRKDGDSIGARINVVASGVPVGLGEPLFDRLDADIAHAMMGINAV
KGVEIGAGFASVAQRGSVHGDELTPEGFVGNHAGGVLGGISTGQDITVSIAIKPTSSIRTPRRSIDKNGQPAVVETFGRH
DPCVGIRATPIAEAMLALVLIDHALRHRAQCGDVVVGTPKIAASAP
>Mature_365_residues
SGNTLGTLFTVTTFGESHGPAIGCVIDGCPPGMSLAEADIQLELDRRKPGTSRHVTQRQEEDKVEILSGVFEGKTTGAPI
ALLIRNTDQRSKDYGNIADTFRPGHADYTYWQKFGIRDYRGGGRSSARLTAPTVAAGAVAKKWLREKFGTEIRGYMAALG
EIDVPFIDWQFVRENPFFVPNADVVPQLEAYMDALRKDGDSIGARINVVASGVPVGLGEPLFDRLDADIAHAMMGINAVK
GVEIGAGFASVAQRGSVHGDELTPEGFVGNHAGGVLGGISTGQDITVSIAIKPTSSIRTPRRSIDKNGQPAVVETFGRHD
PCVGIRATPIAEAMLALVLIDHALRHRAQCGDVVVGTPKIAASAP

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family

Homologues:

Organism=Escherichia coli, GI1788669, Length=360, Percent_Identity=65.8333333333333, Blast_Score=466, Evalue=1e-133,
Organism=Saccharomyces cerevisiae, GI6321290, Length=367, Percent_Identity=44.141689373297, Blast_Score=295, Evalue=1e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROC_BURP8 (B2JK28)

Other databases:

- EMBL:   CP001043
- RefSeq:   YP_001857797.1
- ProteinModelPortal:   B2JK28
- SMR:   B2JK28
- GeneID:   6243060
- GenomeReviews:   CP001043_GR
- KEGG:   bph:Bphy_1569
- HOGENOM:   HBG292336
- OMA:   SRFTTQR
- ProtClustDB:   PRK05382
- HAMAP:   MF_00300_B
- InterPro:   IPR000453
- InterPro:   IPR020541
- PANTHER:   PTHR21085
- PIRSF:   PIRSF001456
- TIGRFAMs:   TIGR00033

Pfam domain/function: PF01264 Chorismate_synt; SSF103263 Chorismate_synth

EC number: =4.2.3.5

Molecular weight: Translated: 38896; Mature: 38764

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1; PS00788 CHORISMATE_SYNTHASE_2; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGNTLGTLFTVTTFGESHGPAIGCVIDGCPPGMSLAEADIQLELDRRKPGTSRHVTQRQ
CCCCEEEEEEEEEECCCCCCCEEEEEEECCCCCCCEECCCEEEEECCCCCCCCHHHHHHH
EEDKVEILSGVFEGKTTGAPIALLIRNTDQRSKDYGNIADTFRPGHADYTYWQKFGIRDY
HHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCHHHHCCCCCCCCHHHHHCCCCCC
RGGGRSSARLTAPTVAAGAVAKKWLREKFGTEIRGYMAALGEIDVPFIDWQFVRENPFFV
CCCCCCCCEEECCHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCEECEEEECCCCCCC
PNADVVPQLEAYMDALRKDGDSIGARINVVASGVPVGLGEPLFDRLDADIAHAMMGINAV
CCCCCCHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHH
KGVEIGAGFASVAQRGSVHGDELTPEGFVGNHAGGVLGGISTGQDITVSIAIKPTSSIRT
CCCEECCCHHHHHHCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCEEEEEEEECCHHCCC
PRRSIDKNGQPAVVETFGRHDPCVGIRATPIAEAMLALVLIDHALRHRAQCGDVVVGTPK
CHHHHCCCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCC
IAASAP
CCCCCC
>Mature Secondary Structure 
SGNTLGTLFTVTTFGESHGPAIGCVIDGCPPGMSLAEADIQLELDRRKPGTSRHVTQRQ
CCCEEEEEEEEEECCCCCCCEEEEEEECCCCCCCEECCCEEEEECCCCCCCCHHHHHHH
EEDKVEILSGVFEGKTTGAPIALLIRNTDQRSKDYGNIADTFRPGHADYTYWQKFGIRDY
HHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCHHHHCCCCCCCCHHHHHCCCCCC
RGGGRSSARLTAPTVAAGAVAKKWLREKFGTEIRGYMAALGEIDVPFIDWQFVRENPFFV
CCCCCCCCEEECCHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCEECEEEECCCCCCC
PNADVVPQLEAYMDALRKDGDSIGARINVVASGVPVGLGEPLFDRLDADIAHAMMGINAV
CCCCCCHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHH
KGVEIGAGFASVAQRGSVHGDELTPEGFVGNHAGGVLGGISTGQDITVSIAIKPTSSIRT
CCCEECCCHHHHHHCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCEEEEEEEECCHHCCC
PRRSIDKNGQPAVVETFGRHDPCVGIRATPIAEAMLALVLIDHALRHRAQCGDVVVGTPK
CHHHHCCCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCC
IAASAP
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA