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The map label for this gene is infC [H]

Identifier: 186476315

GI number: 186476315

Start: 1763852

End: 1764322

Strand: Reverse

Name: infC [H]

Synonym: Bphy_1557

Alternate gene names: 186476315

Gene position: 1764322-1763852 (Counterclockwise)

Preceding gene: 186476316

Following gene: 186476314

Centisome position: 50.71

GC content: 57.11

Gene sequence:

>471_bases
GTGCGTCTGGTCGGAGTCGACAACGAACCGCTCGGCATCGTAAAACTCGCTGAAGCTTTCCGCCTGTCGGAGCAGCAGGA
CGTGGATCTGGTTGAAATCGCGCCGCAAGCGGTTCCGCCTGTCTGCCGCCTGATGGACTACGGCAAGTTCAAGTACCAGG
AAGCGAAGAAGCAGCACGAGGCCAAGCTCAAGCAGAAGGTCATCCAGGTTAAGGAAGTCAAGTTCCGGCCGGGCACGGAT
GACGGTGACTACAATGTCAAGCTGCGCAATCTCGTCCGCTTCCTCGAAGATGGCGACAAGACGAAGATCACGTTGCGTTT
CCGTGGCCGCGAAATGGCTCACCAGGAAATCGGTATGCGCATGCTTGAACGCCTGCGCACCGACTTGGACGAAGTCGGTC
AGGTCGAGCAAATGCCGAAGATGGAAGGCCGCCAGATGATCATGGTGCTGGCGCCGAAGAAAAAGAAGTAA

Upstream 100 bases:

>100_bases
CCCAGGCAGCGCGGCTCGTTTTTTTAATTTTTAGAGGAAACGTAACATCGCTACTGATAAGTCGTCGCATCGCATAAACG
GTGAAATTACTGCACCTGAA

Downstream 100 bases:

>100_bases
GCAGACGCCCGCTGTGCATCTCAAGCATGCGCGGCGTTCGTCGGAAAGTTTCAGTGTGCGTCGTCTTGAAGGCGACGTGT
ACGACGCAGGTTTCGGAGCG

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 156; Mature: 156

Protein sequence:

>156_residues
MRLVGVDNEPLGIVKLAEAFRLSEQQDVDLVEIAPQAVPPVCRLMDYGKFKYQEAKKQHEAKLKQKVIQVKEVKFRPGTD
DGDYNVKLRNLVRFLEDGDKTKITLRFRGREMAHQEIGMRMLERLRTDLDEVGQVEQMPKMEGRQMIMVLAPKKKK

Sequences:

>Translated_156_residues
MRLVGVDNEPLGIVKLAEAFRLSEQQDVDLVEIAPQAVPPVCRLMDYGKFKYQEAKKQHEAKLKQKVIQVKEVKFRPGTD
DGDYNVKLRNLVRFLEDGDKTKITLRFRGREMAHQEIGMRMLERLRTDLDEVGQVEQMPKMEGRQMIMVLAPKKKK
>Mature_156_residues
MRLVGVDNEPLGIVKLAEAFRLSEQQDVDLVEIAPQAVPPVCRLMDYGKFKYQEAKKQHEAKLKQKVIQVKEVKFRPGTD
DGDYNVKLRNLVRFLEDGDKTKITLRFRGREMAHQEIGMRMLERLRTDLDEVGQVEQMPKMEGRQMIMVLAPKKKK

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=157, Percent_Identity=67.515923566879, Blast_Score=201, Evalue=2e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 18139; Mature: 18139

Theoretical pI: Translated: 10.03; Mature: 10.03

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.8 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
5.8 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLVGVDNEPLGIVKLAEAFRLSEQQDVDLVEIAPQAVPPVCRLMDYGKFKYQEAKKQHE
CEEECCCCCCCHHHHHHHHHHCCCCCCCCHHHHCCCCCCHHHHHHHCCCHHHHHHHHHHH
AKLKQKVIQVKEVKFRPGTDDGDYNVKLRNLVRFLEDGDKTKITLRFRGREMAHQEIGMR
HHHHHHHHHHHHHCCCCCCCCCCCEEEHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHH
MLERLRTDLDEVGQVEQMPKMEGRQMIMVLAPKKKK
HHHHHHHCHHHHHHHHHCCCCCCCEEEEEECCCCCC
>Mature Secondary Structure
MRLVGVDNEPLGIVKLAEAFRLSEQQDVDLVEIAPQAVPPVCRLMDYGKFKYQEAKKQHE
CEEECCCCCCCHHHHHHHHHHCCCCCCCCHHHHCCCCCCHHHHHHHCCCHHHHHHHHHHH
AKLKQKVIQVKEVKFRPGTDDGDYNVKLRNLVRFLEDGDKTKITLRFRGREMAHQEIGMR
HHHHHHHHHHHHHCCCCCCCCCCCEEEHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHH
MLERLRTDLDEVGQVEQMPKMEGRQMIMVLAPKKKK
HHHHHHHCHHHHHHHHHCCCCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]