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The map label for this gene is argA [H]

Identifier: 186476247

GI number: 186476247

Start: 1684811

End: 1686190

Strand: Direct

Name: argA [H]

Synonym: Bphy_1489

Alternate gene names: 186476247

Gene position: 1684811-1686190 (Clockwise)

Preceding gene: 186476245

Following gene: 186476248

Centisome position: 48.43

GC content: 64.35

Gene sequence:

>1380_bases
ATGAATTCCCAAACCGACCTCGTCCCCTCGCCCGCCTCAGCACCGGCACCGTCCGGCGACGCGGAAACCCTGTTGCAGCA
CGCGCAATTCGTCGACTGGATGCGATCGGTCGCGCCGTATATCCACGCGTTCCGAAACAAGACGTTTGTCGTCGGGTTCG
GCGGCGAGGTCGTGCATCAGGGTCTGCTCAACGCGCTCGTCTCCGACATCGCGCTGTTACAGGCAATGGGTATCCAGATC
GTGCTCGTGCATGGCTCGCGTCCGCAAGTGGAAGAGCAGATGAGCCTGCACGGCGTCGAGTCCGAGTTTTCGCACGGCAT
GCGCATCACCAATGCGCGCGCGCTCGAATCCGCGAAGGAAGCCGCAGGCGAAGTGCGTCTCGACATCGAGGCCGCGATCA
GCCAGGGTCTGCCGAACACGCCCATGGCGCACGCGCACATCAGCGTCGTGTCGGGCAACTTCGTGACGGCGCGCCCGGTC
GGCATTCTCGACGGGGTCGATTTCCAGCACACGGGTGTCGTGCGCAAGATCGATGCCGAGTCGATCCGTCAATCGCTTGC
GAGCGGCAAGATCGTGCTGCTCTCGCCGCTCGGCTTTTCGCCGACGGGCGAAGCGTTCAATCTGGCGATGGAAGACGTCG
CGTCGGCTGCCGCGATCGCGCTGCGCGCCGACAAGATCGTGTTTCTGACCGAAACGGAAGGTCTGCTCGACGAAGAAGGC
GCGCTGCTGCGCGAACTGTCGCTTGACGACGCTTACCGCCTGCATGAAAGCGGTGCTGTAACGGGCGACGCCGGCTTCTA
TCTGAAGCACTCTATTCGCGCATGCCGCGGCGGCGTCGCGCGGGCGCACATCATTCCATACGCGCTCGACGGCAGCCTGC
TGCTGGAACTGTTCTTGCACGACGGCGTGGGCACGATGATTTCGTACGAGAACCTCGAAAGCCTGCGCGAAGCCTCGCCG
GACGACGTCGGCGGCATTCTCACGCTGATCGAGCCACTGGAAAGCGACGGCACGCTCGTGCGGCGCGGGCGCCACCAGAT
CGAGCGCGACATCGACCATTTCTCGGTGATCGAGCACGATGGCGTGCTATTCGGCTGCGCAGCGCTGTATCCGTATCCGC
AGGAGCGCATCGGCGAGATGGCCTGCCTGACGGTCGCACCGGAAGCACAGGGTTCGGGCGACGGCGAGCGGCTGCTCAAG
CGTATCGAGCAGCGCGCGCGGGCTCGCGGACTCGCCCGTATCTTCGTGCTGACGACGCGCACCGAGCACTGGTTCCTCAA
GCGCGGCTTCGTGAAGGTCACGGTCGACGATCTTCCCGAAGACCGCCGCCGCCTCTACAACTGGCAGCGCAAGTCGCTCG
TGCTGATGAAACAGCTCTGA

Upstream 100 bases:

>100_bases
TTCGCGGCGTCTTTCGCGTTATCGGACGGAGCGTTTTTCGTATCGGCTCCAGCGGAGCTTTTGGGTACATTCGACATGGG
GGCGCATTATAATCCGGGGC

Downstream 100 bases:

>100_bases
GCGCGCACAATAACGCCGCGACGCCGTTACATATCGATTACAGGAGAAGCACAGCATGACTCGCATGGTTCAATGCACGA
AGCTCGGCAAGGAAGCCGAA

Product: N-acetylglutamate synthase

Products: NA

Alternate protein names: N-acetylglutamate synthase; AGS; NAGS [H]

Number of amino acids: Translated: 459; Mature: 459

Protein sequence:

>459_residues
MNSQTDLVPSPASAPAPSGDAETLLQHAQFVDWMRSVAPYIHAFRNKTFVVGFGGEVVHQGLLNALVSDIALLQAMGIQI
VLVHGSRPQVEEQMSLHGVESEFSHGMRITNARALESAKEAAGEVRLDIEAAISQGLPNTPMAHAHISVVSGNFVTARPV
GILDGVDFQHTGVVRKIDAESIRQSLASGKIVLLSPLGFSPTGEAFNLAMEDVASAAAIALRADKIVFLTETEGLLDEEG
ALLRELSLDDAYRLHESGAVTGDAGFYLKHSIRACRGGVARAHIIPYALDGSLLLELFLHDGVGTMISYENLESLREASP
DDVGGILTLIEPLESDGTLVRRGRHQIERDIDHFSVIEHDGVLFGCAALYPYPQERIGEMACLTVAPEAQGSGDGERLLK
RIEQRARARGLARIFVLTTRTEHWFLKRGFVKVTVDDLPEDRRRLYNWQRKSLVLMKQL

Sequences:

>Translated_459_residues
MNSQTDLVPSPASAPAPSGDAETLLQHAQFVDWMRSVAPYIHAFRNKTFVVGFGGEVVHQGLLNALVSDIALLQAMGIQI
VLVHGSRPQVEEQMSLHGVESEFSHGMRITNARALESAKEAAGEVRLDIEAAISQGLPNTPMAHAHISVVSGNFVTARPV
GILDGVDFQHTGVVRKIDAESIRQSLASGKIVLLSPLGFSPTGEAFNLAMEDVASAAAIALRADKIVFLTETEGLLDEEG
ALLRELSLDDAYRLHESGAVTGDAGFYLKHSIRACRGGVARAHIIPYALDGSLLLELFLHDGVGTMISYENLESLREASP
DDVGGILTLIEPLESDGTLVRRGRHQIERDIDHFSVIEHDGVLFGCAALYPYPQERIGEMACLTVAPEAQGSGDGERLLK
RIEQRARARGLARIFVLTTRTEHWFLKRGFVKVTVDDLPEDRRRLYNWQRKSLVLMKQL
>Mature_459_residues
MNSQTDLVPSPASAPAPSGDAETLLQHAQFVDWMRSVAPYIHAFRNKTFVVGFGGEVVHQGLLNALVSDIALLQAMGIQI
VLVHGSRPQVEEQMSLHGVESEFSHGMRITNARALESAKEAAGEVRLDIEAAISQGLPNTPMAHAHISVVSGNFVTARPV
GILDGVDFQHTGVVRKIDAESIRQSLASGKIVLLSPLGFSPTGEAFNLAMEDVASAAAIALRADKIVFLTETEGLLDEEG
ALLRELSLDDAYRLHESGAVTGDAGFYLKHSIRACRGGVARAHIIPYALDGSLLLELFLHDGVGTMISYENLESLREASP
DDVGGILTLIEPLESDGTLVRRGRHQIERDIDHFSVIEHDGVLFGCAALYPYPQERIGEMACLTVAPEAQGSGDGERLLK
RIEQRARARGLARIFVLTTRTEHWFLKRGFVKVTVDDLPEDRRRLYNWQRKSLVLMKQL

Specific function: Arginine biosynthesis; first step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

Organism=Escherichia coli, GI1789181, Length=438, Percent_Identity=45.662100456621, Blast_Score=420, Evalue=1e-118,
Organism=Saccharomyces cerevisiae, GI6320913, Length=297, Percent_Identity=24.2424242424242, Blast_Score=78, Evalue=2e-15,

Paralogues:

None

Copy number: 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR001048
- InterPro:   IPR010167 [H]

Pfam domain/function: PF00696 AA_kinase; PF00583 Acetyltransf_1 [H]

EC number: =2.3.1.1 [H]

Molecular weight: Translated: 50102; Mature: 50102

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSQTDLVPSPASAPAPSGDAETLLQHAQFVDWMRSVAPYIHAFRNKTFVVGFGGEVVHQ
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHH
GLLNALVSDIALLQAMGIQIVLVHGSRPQVEEQMSLHGVESEFSHGMRITNARALESAKE
HHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHCCCHHHHHCCEEECHHHHHHHHHH
AAGEVRLDIEAAISQGLPNTPMAHAHISVVSGNFVTARPVGILDGVDFQHTGVVRKIDAE
CCCCEEEEHHHHHHCCCCCCCCCEEEEEEEECCEEEECCCCEECCCCCCCCCCEEECCHH
SIRQSLASGKIVLLSPLGFSPTGEAFNLAMEDVASAAAIALRADKIVFLTETEGLLDEEG
HHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHEEECCEEEEEECCCCCCCCCC
ALLRELSLDDAYRLHESGAVTGDAGFYLKHSIRACRGGVARAHIIPYALDGSLLLELFLH
HHHHHCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEEECCHHHHHHHHHH
DGVGTMISYENLESLREASPDDVGGILTLIEPLESDGTLVRRGRHQIERDIDHFSVIEHD
CCCCCEEEHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHEEECC
GVLFGCAALYPYPQERIGEMACLTVAPEAQGSGDGERLLKRIEQRARARGLARIFVLTTR
CEEEEHHHHCCCCHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCEEEEEEEEEC
TEHWFLKRGFVKVTVDDLPEDRRRLYNWQRKSLVLMKQL
CHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNSQTDLVPSPASAPAPSGDAETLLQHAQFVDWMRSVAPYIHAFRNKTFVVGFGGEVVHQ
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHH
GLLNALVSDIALLQAMGIQIVLVHGSRPQVEEQMSLHGVESEFSHGMRITNARALESAKE
HHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHCCCHHHHHCCEEECHHHHHHHHHH
AAGEVRLDIEAAISQGLPNTPMAHAHISVVSGNFVTARPVGILDGVDFQHTGVVRKIDAE
CCCCEEEEHHHHHHCCCCCCCCCEEEEEEEECCEEEECCCCEECCCCCCCCCCEEECCHH
SIRQSLASGKIVLLSPLGFSPTGEAFNLAMEDVASAAAIALRADKIVFLTETEGLLDEEG
HHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHEEECCEEEEEECCCCCCCCCC
ALLRELSLDDAYRLHESGAVTGDAGFYLKHSIRACRGGVARAHIIPYALDGSLLLELFLH
HHHHHCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEEECCHHHHHHHHHH
DGVGTMISYENLESLREASPDDVGGILTLIEPLESDGTLVRRGRHQIERDIDHFSVIEHD
CCCCCEEEHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHEEECC
GVLFGCAALYPYPQERIGEMACLTVAPEAQGSGDGERLLKRIEQRARARGLARIFVLTTR
CEEEEHHHHCCCCHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCEEEEEEEEEC
TEHWFLKRGFVKVTVDDLPEDRRRLYNWQRKSLVLMKQL
CHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]