Click here to switch to the map view.

The map label for this gene is prlC [H]

Identifier: 186476234

GI number: 186476234

Start: 1664151

End: 1666265

Strand: Direct

Name: prlC [H]

Synonym: Bphy_1476

Alternate gene names: 186476234

Gene position: 1664151-1666265 (Clockwise)

Preceding gene: 186476233

Following gene: 186476236

Centisome position: 47.83

GC content: 62.88

Gene sequence:

>2115_bases
ATGTCCACTTCACAATCGACATCCGATAATCCGCTCCTCGATTTCTCCGATCTGCCGCGCTTTGGCGAGATCCGCCCCGA
ACATGTGACGCCTGCCCTCGATGTGCTGCTCGCGAACGCGACGGCCGCCGTCGAACGGGCTGCCGAGCCGTCGACGCCCG
CATCATGGGCCGACGTCGTCGAGCCCGTCGAGCGCGCGACGGAACCGCTGTCGCGCGCATGGGGCGTGATCGGCCATCTG
AATGCCGTCGCCGACACGCCCGAGTTGCGCGCCGTGTACGGCGAAAACCTGCCGCGCGTGACCGAGTTCTGGTCGAGCGT
CGGGCAAAATCTCGCGCTCTACGAAAAGTACAAGACGATCGCCGCCAGCAACGATTTCGAATCGCTCACAGCCGAGCGCA
AGAAGATTCTCAACAACTCGCTGCGTGACTTCAGGCTGTCGGGCGCCGAACTGCCCGAAGATCAAAAGCCGCGGTTCGCC
GAACTGCAGGAACGTCAGGCCGCGCTGTCGAAGGCATTTTCGGATCATGTGCTCGATGCGACGAATGCGTATGCGTATAT
TGCCGAGAGCAAGGATGAACTGGCGGGCCTGCCCGAAGACGTCATCGAGGCAGCGCGCGAAGCAGCCGAGCGCGAAACCA
AGAGCGGGTGGAAGTTCACGCTGCACTTCCCGTCCTACTTCCCGGTGATGCAGTACTCGGAAAATCGCGCGATGCGCGAA
ACGATGTACCGCGCTTACGTCACGCGTGCGTCCGAGCTCGGGCCGCAATACGGCAAGGGCAACGCCGACTGGGACAACAC
AGCGAACATCGCGGAGAACCTGAAGCTGCGCGAAGAAGAAGCGCACATGCTCGGGTACAGGAATTTCGCGGAGGTATCGC
TGGCGCCGAAGATGGCGGAGTCGCCGGAACAGGTGATGGCCTTCCTCGAAGACCTCGCGACTCGTGCCCGGCCGCACGCC
GAGCACGACTGGGCGGAACTGCGCGAGTTCTCCGCCAGCGAGCTTGGCCTGAGCGAACTGCAGCCGTGGGATATGGCGTT
TGCCGCCGAGCGGCTGCGCCAGAAGCGCTACTCGTTCTCCGAAAACGAAGTGAAACAGTACTTTCCGGAAGACATCGTGC
TGAAGGGCCTGTTCAAGGTCACGGAGACGCTGTTCGGCGTGAAGATCCGCCGCGACGAAGCGGCGACCTGGCACCCCGAT
GTACGCTTCTTCCGTGTCGAGAATCAGGACGGCGGCCTGGTCGCTCAATTCTATCTCGACCTGTACGCGCGCGAAGGCAA
GCGCGGTGGCGCATGGATGGATGATGCGCGCTCACGCCGCAAGCCCGTGAACGGCGCGGTGCAAACGCCCGTCGCGTATC
TGACGTGCAACTTCTCCGCGCCCGTCGGCGGCAAGCCTGCCTGCTTCACGCACGATGAAGTGATCACGTTGTTCCACGAA
TTCGGCCACGGCCTGCATCACATGCTGACTCGCGTCGACGAACTCGGCGTATCGGGCATCAACGGTGTCGAATGGGATGC
CGTCGAACTGCCGTCGCAGTTCATGGAGAACTTCTGCTGGGAGTGGGACGTGCTGAGCGGCATGACGCAGCATGTCGACA
CGGCGAAACCGCTGCCGCGCGACCTGTTCGACAAGATGCTCGCCGCGAAGAACTTCCAGAGCGGTCTCGGCACGCTGCGC
CAGATCGTGTTCTCGATGTTCGACATGACGCTGCATGTGGACTTCGACACGTCCGGTGCGAAAAGCGCGAACGATCTGGC
GCGCGAGATCAACGAGCGCTTCCACGTGATTCCGCAAGCAGCGTTCTCGCGCTGGCCGAACACCTTCAGCCACATCTTCG
CGGGCGGCTATGCGGCAGGTTACTACAGCTACAAGTGGGCCGAAGTCTTGTCCGCCGATGCGTACGCTGCGTTCGAAGAA
GCGGCGCAGGCAGGCAAAGGCAGTGTGCTCGATGCGGCAACGGGCACGCGCTATCGCAAGGAGATTCTCGAAGTGGGCGG
CAGCCGCCCCGCGATGGAATCGTTCAAGGCGTTTCGCGGCCGCGAGCCGAACATCGATGCGCTGCTGCGTCACAACGGCA
TGGCGCCGGGTTCGGCGCCGGGCGCAGCGCATTGA

Upstream 100 bases:

>100_bases
GGCATGATCCGCGCGCCGCTTGCCACGCCGCGCCGCTCCCGTTTCAGACCCGGACGGATATATTCCGGGGCTCCATTTAC
CGCGTCAGACAGGAAGCATC

Downstream 100 bases:

>100_bases
GGCAGCGCTAACGCCGTCAGCCGCCGCCTGTCGAAGCGCCTGCATCTTCCGGCGCTTCGATCAGGTCGGCGTTCGGGCAC
ACGCGAAGCGGGCTCGGTTT

Product: oligopeptidase A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 704; Mature: 703

Protein sequence:

>704_residues
MSTSQSTSDNPLLDFSDLPRFGEIRPEHVTPALDVLLANATAAVERAAEPSTPASWADVVEPVERATEPLSRAWGVIGHL
NAVADTPELRAVYGENLPRVTEFWSSVGQNLALYEKYKTIAASNDFESLTAERKKILNNSLRDFRLSGAELPEDQKPRFA
ELQERQAALSKAFSDHVLDATNAYAYIAESKDELAGLPEDVIEAAREAAERETKSGWKFTLHFPSYFPVMQYSENRAMRE
TMYRAYVTRASELGPQYGKGNADWDNTANIAENLKLREEEAHMLGYRNFAEVSLAPKMAESPEQVMAFLEDLATRARPHA
EHDWAELREFSASELGLSELQPWDMAFAAERLRQKRYSFSENEVKQYFPEDIVLKGLFKVTETLFGVKIRRDEAATWHPD
VRFFRVENQDGGLVAQFYLDLYAREGKRGGAWMDDARSRRKPVNGAVQTPVAYLTCNFSAPVGGKPACFTHDEVITLFHE
FGHGLHHMLTRVDELGVSGINGVEWDAVELPSQFMENFCWEWDVLSGMTQHVDTAKPLPRDLFDKMLAAKNFQSGLGTLR
QIVFSMFDMTLHVDFDTSGAKSANDLAREINERFHVIPQAAFSRWPNTFSHIFAGGYAAGYYSYKWAEVLSADAYAAFEE
AAQAGKGSVLDAATGTRYRKEILEVGGSRPAMESFKAFRGREPNIDALLRHNGMAPGSAPGAAH

Sequences:

>Translated_704_residues
MSTSQSTSDNPLLDFSDLPRFGEIRPEHVTPALDVLLANATAAVERAAEPSTPASWADVVEPVERATEPLSRAWGVIGHL
NAVADTPELRAVYGENLPRVTEFWSSVGQNLALYEKYKTIAASNDFESLTAERKKILNNSLRDFRLSGAELPEDQKPRFA
ELQERQAALSKAFSDHVLDATNAYAYIAESKDELAGLPEDVIEAAREAAERETKSGWKFTLHFPSYFPVMQYSENRAMRE
TMYRAYVTRASELGPQYGKGNADWDNTANIAENLKLREEEAHMLGYRNFAEVSLAPKMAESPEQVMAFLEDLATRARPHA
EHDWAELREFSASELGLSELQPWDMAFAAERLRQKRYSFSENEVKQYFPEDIVLKGLFKVTETLFGVKIRRDEAATWHPD
VRFFRVENQDGGLVAQFYLDLYAREGKRGGAWMDDARSRRKPVNGAVQTPVAYLTCNFSAPVGGKPACFTHDEVITLFHE
FGHGLHHMLTRVDELGVSGINGVEWDAVELPSQFMENFCWEWDVLSGMTQHVDTAKPLPRDLFDKMLAAKNFQSGLGTLR
QIVFSMFDMTLHVDFDTSGAKSANDLAREINERFHVIPQAAFSRWPNTFSHIFAGGYAAGYYSYKWAEVLSADAYAAFEE
AAQAGKGSVLDAATGTRYRKEILEVGGSRPAMESFKAFRGREPNIDALLRHNGMAPGSAPGAAH
>Mature_703_residues
STSQSTSDNPLLDFSDLPRFGEIRPEHVTPALDVLLANATAAVERAAEPSTPASWADVVEPVERATEPLSRAWGVIGHLN
AVADTPELRAVYGENLPRVTEFWSSVGQNLALYEKYKTIAASNDFESLTAERKKILNNSLRDFRLSGAELPEDQKPRFAE
LQERQAALSKAFSDHVLDATNAYAYIAESKDELAGLPEDVIEAAREAAERETKSGWKFTLHFPSYFPVMQYSENRAMRET
MYRAYVTRASELGPQYGKGNADWDNTANIAENLKLREEEAHMLGYRNFAEVSLAPKMAESPEQVMAFLEDLATRARPHAE
HDWAELREFSASELGLSELQPWDMAFAAERLRQKRYSFSENEVKQYFPEDIVLKGLFKVTETLFGVKIRRDEAATWHPDV
RFFRVENQDGGLVAQFYLDLYAREGKRGGAWMDDARSRRKPVNGAVQTPVAYLTCNFSAPVGGKPACFTHDEVITLFHEF
GHGLHHMLTRVDELGVSGINGVEWDAVELPSQFMENFCWEWDVLSGMTQHVDTAKPLPRDLFDKMLAAKNFQSGLGTLRQ
IVFSMFDMTLHVDFDTSGAKSANDLAREINERFHVIPQAAFSRWPNTFSHIFAGGYAAGYYSYKWAEVLSADAYAAFEEA
AQAGKGSVLDAATGTRYRKEILEVGGSRPAMESFKAFRGREPNIDALLRHNGMAPGSAPGAAH

Specific function: May play a specific role in the degradation of signal peptides after they are released from precursor forms of secreted proteins. Can cleave N-acetyl-L-Ala(4) [H]

COG id: COG0339

COG function: function code E; Zn-dependent oligopeptidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M3 family [H]

Homologues:

Organism=Homo sapiens, GI4507491, Length=625, Percent_Identity=30.24, Blast_Score=298, Evalue=1e-80,
Organism=Homo sapiens, GI14149738, Length=621, Percent_Identity=31.2399355877617, Blast_Score=281, Evalue=1e-75,
Organism=Homo sapiens, GI156105687, Length=689, Percent_Identity=24.9637155297533, Blast_Score=181, Evalue=2e-45,
Organism=Escherichia coli, GI1789913, Length=687, Percent_Identity=48.9082969432314, Blast_Score=680, Evalue=0.0,
Organism=Escherichia coli, GI1787819, Length=697, Percent_Identity=29.9856527977045, Blast_Score=267, Evalue=2e-72,
Organism=Caenorhabditis elegans, GI71999758, Length=529, Percent_Identity=24.5746691871456, Blast_Score=134, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI32565901, Length=594, Percent_Identity=21.3804713804714, Blast_Score=93, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6319793, Length=696, Percent_Identity=26.5804597701149, Blast_Score=264, Evalue=3e-71,
Organism=Saccharomyces cerevisiae, GI6322715, Length=608, Percent_Identity=24.1776315789474, Blast_Score=146, Evalue=1e-35,
Organism=Drosophila melanogaster, GI21356111, Length=689, Percent_Identity=25.689404934688, Blast_Score=231, Evalue=9e-61,
Organism=Drosophila melanogaster, GI20129717, Length=547, Percent_Identity=24.8628884826325, Blast_Score=171, Evalue=2e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001567 [H]

Pfam domain/function: PF01432 Peptidase_M3 [H]

EC number: =3.4.24.70 [H]

Molecular weight: Translated: 78765; Mature: 78634

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTSQSTSDNPLLDFSDLPRFGEIRPEHVTPALDVLLANATAAVERAAEPSTPASWADVV
CCCCCCCCCCCCCCHHCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
EPVERATEPLSRAWGVIGHLNAVADTPELRAVYGENLPRVTEFWSSVGQNLALYEKYKTI
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHH
AASNDFESLTAERKKILNNSLRDFRLSGAELPEDQKPRFAELQERQAALSKAFSDHVLDA
HCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
TNAYAYIAESKDELAGLPEDVIEAAREAAERETKSGWKFTLHFPSYFPVMQYSENRAMRE
CCCEEEEECCHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHH
TMYRAYVTRASELGPQYGKGNADWDNTANIAENLKLREEEAHMLGYRNFAEVSLAPKMAE
HHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHCC
SPEQVMAFLEDLATRARPHAEHDWAELREFSASELGLSELQPWDMAFAAERLRQKRYSFS
CHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCHHHCCHHHCCCHHHHHHHHHHHHHHCCCC
ENEVKQYFPEDIVLKGLFKVTETLFGVKIRRDEAATWHPDVRFFRVENQDGGLVAQFYLD
HHHHHHHCCHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCEEEEEEECCCCCCHHHHHHH
LYAREGKRGGAWMDDARSRRKPVNGAVQTPVAYLTCNFSAPVGGKPACFTHDEVITLFHE
HHHHCCCCCCCCHHHHHHHCCCCCCCHHCCEEEEEEECCCCCCCCCCEECHHHHHHHHHH
FGHGLHHMLTRVDELGVSGINGVEWDAVELPSQFMENFCWEWDVLSGMTQHVDTAKPLPR
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCH
DLFDKMLAAKNFQSGLGTLRQIVFSMFDMTLHVDFDTSGAKSANDLAREINERFHVIPQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCCHHHHHHHHHHHHHHCCHH
AFSRWPNTFSHIFAGGYAAGYYSYKWAEVLSADAYAAFEEAAQAGKGSVLDAATGTRYRK
HHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHH
EILEVGGSRPAMESFKAFRGREPNIDALLRHNGMAPGSAPGAAH
HHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
STSQSTSDNPLLDFSDLPRFGEIRPEHVTPALDVLLANATAAVERAAEPSTPASWADVV
CCCCCCCCCCCCCHHCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
EPVERATEPLSRAWGVIGHLNAVADTPELRAVYGENLPRVTEFWSSVGQNLALYEKYKTI
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHH
AASNDFESLTAERKKILNNSLRDFRLSGAELPEDQKPRFAELQERQAALSKAFSDHVLDA
HCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
TNAYAYIAESKDELAGLPEDVIEAAREAAERETKSGWKFTLHFPSYFPVMQYSENRAMRE
CCCEEEEECCHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHH
TMYRAYVTRASELGPQYGKGNADWDNTANIAENLKLREEEAHMLGYRNFAEVSLAPKMAE
HHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHCC
SPEQVMAFLEDLATRARPHAEHDWAELREFSASELGLSELQPWDMAFAAERLRQKRYSFS
CHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCHHHCCHHHCCCHHHHHHHHHHHHHHCCCC
ENEVKQYFPEDIVLKGLFKVTETLFGVKIRRDEAATWHPDVRFFRVENQDGGLVAQFYLD
HHHHHHHCCHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCEEEEEEECCCCCCHHHHHHH
LYAREGKRGGAWMDDARSRRKPVNGAVQTPVAYLTCNFSAPVGGKPACFTHDEVITLFHE
HHHHCCCCCCCCHHHHHHHCCCCCCCHHCCEEEEEEECCCCCCCCCCEECHHHHHHHHHH
FGHGLHHMLTRVDELGVSGINGVEWDAVELPSQFMENFCWEWDVLSGMTQHVDTAKPLPR
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCH
DLFDKMLAAKNFQSGLGTLRQIVFSMFDMTLHVDFDTSGAKSANDLAREINERFHVIPQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCCHHHHHHHHHHHHHHCCHH
AFSRWPNTFSHIFAGGYAAGYYSYKWAEVLSADAYAAFEEAAQAGKGSVLDAATGTRYRK
HHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHH
EILEVGGSRPAMESFKAFRGREPNIDALLRHNGMAPGSAPGAAH
HHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]