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The map label for this gene is pbpG [H]

Identifier: 186476224

GI number: 186476224

Start: 1646785

End: 1647948

Strand: Reverse

Name: pbpG [H]

Synonym: Bphy_1466

Alternate gene names: 186476224

Gene position: 1647948-1646785 (Counterclockwise)

Preceding gene: 186476226

Following gene: 186476222

Centisome position: 47.37

GC content: 64.0

Gene sequence:

>1164_bases
ATGAAAACCGACATGTTTTCGTCACTGAAAGTGATGCACGGCGCGGCGCTCAGCACCGCTCTGTCGGTGGCTGCCTCGGT
GGTCATCGCAGCGGCATTTGCCGCGCCGGTGGATGCCTTCGCCGCGTCCGCCACGGCCCCCGTCAAGTCCGCGAAAGCCG
GCAAAAAGTCGTCGAAGAAGGCGGCTGCCGAGAAAGTCTCCAGCCAGCCGTCGAAGGCCGTGAAAGCGGCCGCAAAGGAC
GACGACGAACCCCGTACTGTGTCGAAGAAGCGCCGCGCGTCCTACACGTCGAATGGCCGCCATCACTCGGTCGTGCGCCG
CGTCGCGTTCGAGCCGCGTCAGCCGTCCGTCGGCACCGCGTTCGGCCTGCACGAAACGCCCGACGCGCTGATGCTCCGTT
CGAGCGTCGCCTACGTGGTCGACCAGAACACGTCGGAGTCGCTGTTTGACAAGAACTCGCGCGCGGTCGTACCCATCGCG
TCGATCACCAAGCTGATGACGGCGATGGTCGTGCTGGACTCGAAGGCGGCCATGACCGAGCAGATCGAAGTCACGGACGA
GGACCGCGACTACGAGAAGAACACGGGCTCGCGTCTGTCCGTCGGCTCGGTGCTCTCGCGTGAAGACATGCTGCACATTG
CGCTGATGGCGTCGGAAAACCGTGCGGCGGCTGCGCTGTCGCGCTATTTCCCGGGCGGCCGTCCGGCGTTCATGGCCGCG
ATGAACGCCAAGGCGAAGGCACTGGGCATGACCGACACGCACTTCGAAAACCCGACGGGCCTGACGAGTCAGAACGTGTC
GAGCGCGCGCGACCTGGTGAAGATGGTCAACGCGGCGTATCAGTACCCGTTGATCCGCAAGTTCTCGACGGATCGCAGCT
ACGAGGTGTATACGGGCAAGCGCTCAATCGCCTACAACAGCACGAACGCGCTGGTGCGCAATCCTTCCTGGGAGATCGGC
TTGCAGAAGACGGGCTTCATCAACGAAGCAGGCGAGTGCCTCGTGATGCAGGCGACGATCCACGATCGTCCGATGATCAT
GGTGCTGCTCGATTCGTCGGGCAAGTACTCGCGTTTCGCCGATGCGCAGCGTCTGCGCACCTGGCTTGACAACGGCGGCG
AACAGCGCATCACGAGCGCGGACGCCAACGGCGCCGGGACCTGA

Upstream 100 bases:

>100_bases
AACTCGGTTTAAGGACTTTCGATAAGTGCTTAATATTGCTAATTTTTGACTGTTTTACTACACTGGCGGAAACCCTCTCG
CCGCTCCAACCAGAACACGA

Downstream 100 bases:

>100_bases
GAGGCAACGCGCGTACCCGACGAAAACTAAGAAGCCCCGCATGCGGGGCTTCTTGCATTTATTGCGTGGCTAAGGGGGCG
GGTCAGATTGCTTGCGCCGA

Product: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1

Products: NA

Alternate protein names: DD-endopeptidase; Penicillin-binding protein 5; PBP-5 [H]

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MKTDMFSSLKVMHGAALSTALSVAASVVIAAAFAAPVDAFAASATAPVKSAKAGKKSSKKAAAEKVSSQPSKAVKAAAKD
DDEPRTVSKKRRASYTSNGRHHSVVRRVAFEPRQPSVGTAFGLHETPDALMLRSSVAYVVDQNTSESLFDKNSRAVVPIA
SITKLMTAMVVLDSKAAMTEQIEVTDEDRDYEKNTGSRLSVGSVLSREDMLHIALMASENRAAAALSRYFPGGRPAFMAA
MNAKAKALGMTDTHFENPTGLTSQNVSSARDLVKMVNAAYQYPLIRKFSTDRSYEVYTGKRSIAYNSTNALVRNPSWEIG
LQKTGFINEAGECLVMQATIHDRPMIMVLLDSSGKYSRFADAQRLRTWLDNGGEQRITSADANGAGT

Sequences:

>Translated_387_residues
MKTDMFSSLKVMHGAALSTALSVAASVVIAAAFAAPVDAFAASATAPVKSAKAGKKSSKKAAAEKVSSQPSKAVKAAAKD
DDEPRTVSKKRRASYTSNGRHHSVVRRVAFEPRQPSVGTAFGLHETPDALMLRSSVAYVVDQNTSESLFDKNSRAVVPIA
SITKLMTAMVVLDSKAAMTEQIEVTDEDRDYEKNTGSRLSVGSVLSREDMLHIALMASENRAAAALSRYFPGGRPAFMAA
MNAKAKALGMTDTHFENPTGLTSQNVSSARDLVKMVNAAYQYPLIRKFSTDRSYEVYTGKRSIAYNSTNALVRNPSWEIG
LQKTGFINEAGECLVMQATIHDRPMIMVLLDSSGKYSRFADAQRLRTWLDNGGEQRITSADANGAGT
>Mature_387_residues
MKTDMFSSLKVMHGAALSTALSVAASVVIAAAFAAPVDAFAASATAPVKSAKAGKKSSKKAAAEKVSSQPSKAVKAAAKD
DDEPRTVSKKRRASYTSNGRHHSVVRRVAFEPRQPSVGTAFGLHETPDALMLRSSVAYVVDQNTSESLFDKNSRAVVPIA
SITKLMTAMVVLDSKAAMTEQIEVTDEDRDYEKNTGSRLSVGSVLSREDMLHIALMASENRAAAALSRYFPGGRPAFMAA
MNAKAKALGMTDTHFENPTGLTSQNVSSARDLVKMVNAAYQYPLIRKFSTDRSYEVYTGKRSIAYNSTNALVRNPSWEIG
LQKTGFINEAGECLVMQATIHDRPMIMVLLDSSGKYSRFADAQRLRTWLDNGGEQRITSADANGAGT

Specific function: Cell wall formation [H]

COG id: COG1686

COG function: function code M; D-alanyl-D-alanine carboxypeptidase

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S11 family [H]

Homologues:

Organism=Escherichia coli, GI87082054, Length=253, Percent_Identity=47.8260869565217, Blast_Score=235, Evalue=3e-63,
Organism=Escherichia coli, GI1787062, Length=262, Percent_Identity=28.2442748091603, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI87082022, Length=256, Percent_Identity=28.515625, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1786851, Length=245, Percent_Identity=26.530612244898, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR018044
- InterPro:   IPR001967 [H]

Pfam domain/function: PF00768 Peptidase_S11 [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 41634; Mature: 41634

Theoretical pI: Translated: 10.16; Mature: 10.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTDMFSSLKVMHGAALSTALSVAASVVIAAAFAAPVDAFAASATAPVKSAKAGKKSSKK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCHHHH
AAAEKVSSQPSKAVKAAAKDDDEPRTVSKKRRASYTSNGRHHSVVRRVAFEPRQPSVGTA
HHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCE
FGLHETPDALMLRSSVAYVVDQNTSESLFDKNSRAVVPIASITKLMTAMVVLDSKAAMTE
ECCCCCCHHHHHHHHEEEEEECCCCHHHHCCCCCEEEEHHHHHHHHHHHHHHCCCHHHHE
QIEVTDEDRDYEKNTGSRLSVGSVLSREDMLHIALMASENRAAAALSRYFPGGRPAFMAA
EEEECCCCCCCCCCCCCEEEHHHHHHHCCEEEEEEEECCCHHHHHHHHHCCCCCHHHHHH
MNAKAKALGMTDTHFENPTGLTSQNVSSARDLVKMVNAAYQYPLIRKFSTDRSYEVYTGK
HCCCHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHCCCCCEEEEECC
RSIAYNSTNALVRNPSWEIGLQKTGFINEAGECLVMQATIHDRPMIMVLLDSSGKYSRFA
EEEEECCCCCEEECCCCEECCCCCCCCCCCCCEEEEEEEECCCCEEEEEECCCCCCHHHH
DAQRLRTWLDNGGEQRITSADANGAGT
HHHHHHHHHHCCCCCEEEECCCCCCCC
>Mature Secondary Structure
MKTDMFSSLKVMHGAALSTALSVAASVVIAAAFAAPVDAFAASATAPVKSAKAGKKSSKK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCHHHH
AAAEKVSSQPSKAVKAAAKDDDEPRTVSKKRRASYTSNGRHHSVVRRVAFEPRQPSVGTA
HHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCE
FGLHETPDALMLRSSVAYVVDQNTSESLFDKNSRAVVPIASITKLMTAMVVLDSKAAMTE
ECCCCCCHHHHHHHHEEEEEECCCCHHHHCCCCCEEEEHHHHHHHHHHHHHHCCCHHHHE
QIEVTDEDRDYEKNTGSRLSVGSVLSREDMLHIALMASENRAAAALSRYFPGGRPAFMAA
EEEECCCCCCCCCCCCCEEEHHHHHHHCCEEEEEEEECCCHHHHHHHHHCCCCCHHHHHH
MNAKAKALGMTDTHFENPTGLTSQNVSSARDLVKMVNAAYQYPLIRKFSTDRSYEVYTGK
HCCCHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHCCCCCEEEEECC
RSIAYNSTNALVRNPSWEIGLQKTGFINEAGECLVMQATIHDRPMIMVLLDSSGKYSRFA
EEEEECCCCCEEECCCCEECCCCCCCCCCCCCEEEEEEEECCCCEEEEEECCCCCCHHHH
DAQRLRTWLDNGGEQRITSADANGAGT
HHHHHHHHHHCCCCCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]