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The map label for this gene is trpS [H]

Identifier: 186476187

GI number: 186476187

Start: 1609188

End: 1610390

Strand: Reverse

Name: trpS [H]

Synonym: Bphy_1429

Alternate gene names: 186476187

Gene position: 1610390-1609188 (Counterclockwise)

Preceding gene: 186476188

Following gene: 186476186

Centisome position: 46.29

GC content: 63.59

Gene sequence:

>1203_bases
ATGTACCCCGACCGTATCTTCTCCGGCATGCGGCCTACCGGCTCGCTGCACCTCGGCCACTATCACGGCGTGCTGAAAAA
CTGGGTGCGTCTGCAATCCGAGTATCCGTGCTTTTTCTGTGTGGTCGACTGGCACGCGCTGACGACACACTATGAAACGC
CGGAGGTAATCGAGAAGAACGTCTGGGATGTGCTGATCGACTGGCTCGCTTCGGGCATCGATCCCGCGCAGGCGACGCTG
TTCATCCAGAGCCGCGTGCCCGAGCACGCCGAGCTCGCGCTGCTGCTCGGCATGAGCACGCCGCTCAGCTGGCTCGAACG
CGTGCCGACCTACAAGGAGCAGATCGAAAAGCTGCGCGACAAGGACCTCGGCACTTACGGTTTTCTCGGCTACCCGGTGC
TGATGGCGGCGGACATCCTGCTGTATCGCGCGTCGCTCGTGCCCGTCGGTGAGGATCAGGTGCCGCACGTCGAAATGGCG
CGCGAAATGGCGCGGCGCTTCAATTACATGTACGGCCGCGAGCCGGGCTTCGAGGAAAAAGCGAACGAGGCGGCGAAGAA
ACTCGGCGGCAAGCGCTCGAAGCTGTATCACGAGCTGCGCAATGGATATCAGCAGGAAGGCAACGAAGAGGCGCTCGAAA
AAGCCCGCGCGATGCTGTCGGAGTCGCAAAGCCTGTCGATGAGCGACCGCGAGCGCCTCTTCGGCTACCTCGAGGGCTCG
CGCAAGATCATCCTGCCCGAGCCGCAGGTGCTGCTGACGGAAGCGTCGCGCATGCCGGGCCTCGACGGCCAGAAGATGTC
GAAGTCGTATGGCAACACGATCGGTCTGCGTGAAGACGCGGAAACAATCACGAAGAAAGTCCGCACGATGCCGACCGACC
CGGCGCGCGTGCGCCGCACGGATCCGGGCGATCCCGACAAGTGCCCGGTGTGGCAGCTGCATCAGGTCTACACCGACAGC
GAGACGCACGAGTGGGTGCAGAAGGGTTGCCGCTCGGCGGGCATCGGCTGCCTCGAATGCAAGCAGCCGGTGATCGAAGG
CATTCTGCGCGAGCAGCAGCCGATGCTCGAGCGCGCACAGAAGTACATGGACGACCCGTCGCTGCTGCGCGCGATCGTCG
CCGATGGTTGCGACAAGGCGCGCCGTTTCGCGACGGAGACGATGCGCGACGTGCGCGAAGCGATGGGTCTCTCATACACC
TGA

Upstream 100 bases:

>100_bases
CACGCTGACGCGTTTCTGGCTGAGTCCGCTCGTGAATATCGGCTACGCGGCAGTGACGGCTATCCTGACTCCCCTCATTT
CGCTTCTATAAATCAAAACC

Downstream 100 bases:

>100_bases
TGACGGATTGCCTGAACCCGGGCCCGCCGGGCGCCCGCCATACGGCGGTCGGCGAGCCGTCGCGCTGGGTGAAGCGCTGG
GCGCATCTGGTCGATGCGCG

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MYPDRIFSGMRPTGSLHLGHYHGVLKNWVRLQSEYPCFFCVVDWHALTTHYETPEVIEKNVWDVLIDWLASGIDPAQATL
FIQSRVPEHAELALLLGMSTPLSWLERVPTYKEQIEKLRDKDLGTYGFLGYPVLMAADILLYRASLVPVGEDQVPHVEMA
REMARRFNYMYGREPGFEEKANEAAKKLGGKRSKLYHELRNGYQQEGNEEALEKARAMLSESQSLSMSDRERLFGYLEGS
RKIILPEPQVLLTEASRMPGLDGQKMSKSYGNTIGLREDAETITKKVRTMPTDPARVRRTDPGDPDKCPVWQLHQVYTDS
ETHEWVQKGCRSAGIGCLECKQPVIEGILREQQPMLERAQKYMDDPSLLRAIVADGCDKARRFATETMRDVREAMGLSYT

Sequences:

>Translated_400_residues
MYPDRIFSGMRPTGSLHLGHYHGVLKNWVRLQSEYPCFFCVVDWHALTTHYETPEVIEKNVWDVLIDWLASGIDPAQATL
FIQSRVPEHAELALLLGMSTPLSWLERVPTYKEQIEKLRDKDLGTYGFLGYPVLMAADILLYRASLVPVGEDQVPHVEMA
REMARRFNYMYGREPGFEEKANEAAKKLGGKRSKLYHELRNGYQQEGNEEALEKARAMLSESQSLSMSDRERLFGYLEGS
RKIILPEPQVLLTEASRMPGLDGQKMSKSYGNTIGLREDAETITKKVRTMPTDPARVRRTDPGDPDKCPVWQLHQVYTDS
ETHEWVQKGCRSAGIGCLECKQPVIEGILREQQPMLERAQKYMDDPSLLRAIVADGCDKARRFATETMRDVREAMGLSYT
>Mature_400_residues
MYPDRIFSGMRPTGSLHLGHYHGVLKNWVRLQSEYPCFFCVVDWHALTTHYETPEVIEKNVWDVLIDWLASGIDPAQATL
FIQSRVPEHAELALLLGMSTPLSWLERVPTYKEQIEKLRDKDLGTYGFLGYPVLMAADILLYRASLVPVGEDQVPHVEMA
REMARRFNYMYGREPGFEEKANEAAKKLGGKRSKLYHELRNGYQQEGNEEALEKARAMLSESQSLSMSDRERLFGYLEGS
RKIILPEPQVLLTEASRMPGLDGQKMSKSYGNTIGLREDAETITKKVRTMPTDPARVRRTDPGDPDKCPVWQLHQVYTDS
ETHEWVQKGCRSAGIGCLECKQPVIEGILREQQPMLERAQKYMDDPSLLRAIVADGCDKARRFATETMRDVREAMGLSYT

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=169, Percent_Identity=44.9704142011834, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI41352700, Length=169, Percent_Identity=44.9704142011834, Blast_Score=147, Evalue=2e-35,
Organism=Escherichia coli, GI1789786, Length=167, Percent_Identity=45.5089820359281, Blast_Score=161, Evalue=6e-41,
Organism=Caenorhabditis elegans, GI71982800, Length=177, Percent_Identity=36.1581920903955, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI71982793, Length=214, Percent_Identity=32.7102803738318, Blast_Score=118, Evalue=5e-27,
Organism=Saccharomyces cerevisiae, GI6320474, Length=184, Percent_Identity=36.9565217391304, Blast_Score=121, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24666151, Length=172, Percent_Identity=43.0232558139535, Blast_Score=155, Evalue=4e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 45666; Mature: 45666

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYPDRIFSGMRPTGSLHLGHYHGVLKNWVRLQSEYPCFFCVVDWHALTTHYETPEVIEKN
CCCHHHHCCCCCCCCEECHHHHHHHHHHHHHHCCCCEEEEEEEHHHHHCCCCCHHHHHHH
VWDVLIDWLASGIDPAQATLFIQSRVPEHAELALLLGMSTPLSWLERVPTYKEQIEKLRD
HHHHHHHHHHCCCCHHHHHEEHHHCCCCHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHH
KDLGTYGFLGYPVLMAADILLYRASLVPVGEDQVPHVEMAREMARRFNYMYGREPGFEEK
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHH
ANEAAKKLGGKRSKLYHELRNGYQQEGNEEALEKARAMLSESQSLSMSDRERLFGYLEGS
HHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCC
RKIILPEPQVLLTEASRMPGLDGQKMSKSYGNTIGLREDAETITKKVRTMPTDPARVRRT
CEEECCCCHHHHHHHHCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHCCCC
DPGDPDKCPVWQLHQVYTDSETHEWVQKGCRSAGIGCLECKQPVIEGILREQQPMLERAQ
CCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
KYMDDPSLLRAIVADGCDKARRFATETMRDVREAMGLSYT
HHCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MYPDRIFSGMRPTGSLHLGHYHGVLKNWVRLQSEYPCFFCVVDWHALTTHYETPEVIEKN
CCCHHHHCCCCCCCCEECHHHHHHHHHHHHHHCCCCEEEEEEEHHHHHCCCCCHHHHHHH
VWDVLIDWLASGIDPAQATLFIQSRVPEHAELALLLGMSTPLSWLERVPTYKEQIEKLRD
HHHHHHHHHHCCCCHHHHHEEHHHCCCCHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHH
KDLGTYGFLGYPVLMAADILLYRASLVPVGEDQVPHVEMAREMARRFNYMYGREPGFEEK
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHH
ANEAAKKLGGKRSKLYHELRNGYQQEGNEEALEKARAMLSESQSLSMSDRERLFGYLEGS
HHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCC
RKIILPEPQVLLTEASRMPGLDGQKMSKSYGNTIGLREDAETITKKVRTMPTDPARVRRT
CEEECCCCHHHHHHHHCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHCCCC
DPGDPDKCPVWQLHQVYTDSETHEWVQKGCRSAGIGCLECKQPVIEGILREQQPMLERAQ
CCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
KYMDDPSLLRAIVADGCDKARRFATETMRDVREAMGLSYT
HHCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]