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The map label for this gene is engA

Identifier: 186476174

GI number: 186476174

Start: 1594964

End: 1596304

Strand: Reverse

Name: engA

Synonym: Bphy_1416

Alternate gene names: 186476174

Gene position: 1596304-1594964 (Counterclockwise)

Preceding gene: 186476175

Following gene: 186476173

Centisome position: 45.88

GC content: 62.94

Gene sequence:

>1341_bases
ATGAAACCCGTAATTGCCCTCGTCGGGCGCCCCAATGTGGGGAAATCCACGCTGTTCAACCGGCTCACGCGTTCGCGCGA
TGCGCTCGTCGCCGATTTGCCCGGCCTCACGCGCGATCGTCATTACGGCGAAGGGCGAGTGGGCGGCGAACGTCCGTATC
TGGTCGTCGATACGGGCGGCTTCGAGCCCGTCGCGAAGGACGGCATCCTGTTCGAGATGGCGCGCCAGACGCGCCAGGCC
GTCGAGGAATCGGACGTCATCGTGTTCATTGTCGACGGCCGCAACGGTCTCGCGCCGCAAGACAAATCGATCGCCGACTA
TCTGCGCAAGACGGGCCGGCCGATCTTCCTCGTCGTCAACAAGGCCGAGGGGATGAAGTACACGAACGTCGCCGCCGACT
TCTACGAACTGGGCCTCGGTGACCCGCGGGCGATTTCCGCCGCGCATGGCGACGGCGTGACCGAGATGATCAACGAGGCG
CTCGATGTCGCGTACGCGGGCCAGCCGGAAGAAAGCGACGAGGAAAAGGCGCAGCACGGCATCAAGATCGCCATCGTCGG
ACGGCCGAATGTCGGGAAGTCCACGCTGGTTAATACGCTGATCGGCGAAGACCGCGTGATCGCGTTCGACATGCCGGGCA
CGACGCGCGACTCGATCTACGTCGACTTCGAGCGGCAAGGCAAAAAATACACGCTGATCGACACGGCGGGCCTGCGCAAG
CGCGGCAAGGTGTTCGAGGCGATCGAAAAGTTCTCGGTCGTGAAGACGCTGCAGTCGATTTCCGACGCCAATGTCGTGAT
TCTGCTGCTGGACGCGCGCCAGGACATCTCGGAGCAGGACGCGCACATCGCAGGCTTCGTGGTCGAGCAGGGCAGAGCAC
TGGTGGTGGGCGTGAACAAGTGGGACGGGCTCGATCCGCATGTGCGTGAGCGCACCAAATCCGATCTTCAGCGCAAGCTA
AAATTCCTCGAGTTCGCGAAATTCCACTTCATTTCTGCAGCGGAAAAGACGGGGATCGGGCCGCTGATGCGCTCCGTCGA
CGACGCGTACAAGGCCGCGATGTCCAAGCTGCCGACGCCGAAGCTCACGCGCGCGCTGATCGAAGCCGTCGAGTTCCAGC
AGCCGCGGCGCCGGGGCCCCGTGCGTCCGAAGCTGCGCTACGCGCACCAGGGGGGACAGAATCCGCCGATCATCGTGATT
CACGGCAACGCGCTCGACGCCGTTACCGATACGTACAAGCGTTACCTCGAAAACCGCTTCCGGGAAACTTTCGCGCTGAC
GGGCACTCCATTGCGGATAGAGTTCCGGTCCTCGACGAATCCTTACGCGGACAAGGACTGA

Upstream 100 bases:

>100_bases
GTGATAATTTTCGTCAAATGCAGCCGTGCAACGGCCGCATGGCGTTGCCAGCGCGGCAGGTCGACCGTTCGACCCTGCGC
TTCACTGTGAACAAGATCTG

Downstream 100 bases:

>100_bases
CAGAAGGCTGTGAGGCAGGCTGATTCCCGGCTTGAATTCCGGGCTGAAACCCGCATGTACATTGGGTCTTGGCCGAACGG
CCAGGCAAAGCGCTGGTCAA

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA

Number of amino acids: Translated: 446; Mature: 446

Protein sequence:

>446_residues
MKPVIALVGRPNVGKSTLFNRLTRSRDALVADLPGLTRDRHYGEGRVGGERPYLVVDTGGFEPVAKDGILFEMARQTRQA
VEESDVIVFIVDGRNGLAPQDKSIADYLRKTGRPIFLVVNKAEGMKYTNVAADFYELGLGDPRAISAAHGDGVTEMINEA
LDVAYAGQPEESDEEKAQHGIKIAIVGRPNVGKSTLVNTLIGEDRVIAFDMPGTTRDSIYVDFERQGKKYTLIDTAGLRK
RGKVFEAIEKFSVVKTLQSISDANVVILLLDARQDISEQDAHIAGFVVEQGRALVVGVNKWDGLDPHVRERTKSDLQRKL
KFLEFAKFHFISAAEKTGIGPLMRSVDDAYKAAMSKLPTPKLTRALIEAVEFQQPRRRGPVRPKLRYAHQGGQNPPIIVI
HGNALDAVTDTYKRYLENRFRETFALTGTPLRIEFRSSTNPYADKD

Sequences:

>Translated_446_residues
MKPVIALVGRPNVGKSTLFNRLTRSRDALVADLPGLTRDRHYGEGRVGGERPYLVVDTGGFEPVAKDGILFEMARQTRQA
VEESDVIVFIVDGRNGLAPQDKSIADYLRKTGRPIFLVVNKAEGMKYTNVAADFYELGLGDPRAISAAHGDGVTEMINEA
LDVAYAGQPEESDEEKAQHGIKIAIVGRPNVGKSTLVNTLIGEDRVIAFDMPGTTRDSIYVDFERQGKKYTLIDTAGLRK
RGKVFEAIEKFSVVKTLQSISDANVVILLLDARQDISEQDAHIAGFVVEQGRALVVGVNKWDGLDPHVRERTKSDLQRKL
KFLEFAKFHFISAAEKTGIGPLMRSVDDAYKAAMSKLPTPKLTRALIEAVEFQQPRRRGPVRPKLRYAHQGGQNPPIIVI
HGNALDAVTDTYKRYLENRFRETFALTGTPLRIEFRSSTNPYADKD
>Mature_446_residues
MKPVIALVGRPNVGKSTLFNRLTRSRDALVADLPGLTRDRHYGEGRVGGERPYLVVDTGGFEPVAKDGILFEMARQTRQA
VEESDVIVFIVDGRNGLAPQDKSIADYLRKTGRPIFLVVNKAEGMKYTNVAADFYELGLGDPRAISAAHGDGVTEMINEA
LDVAYAGQPEESDEEKAQHGIKIAIVGRPNVGKSTLVNTLIGEDRVIAFDMPGTTRDSIYVDFERQGKKYTLIDTAGLRK
RGKVFEAIEKFSVVKTLQSISDANVVILLLDARQDISEQDAHIAGFVVEQGRALVVGVNKWDGLDPHVRERTKSDLQRKL
KFLEFAKFHFISAAEKTGIGPLMRSVDDAYKAAMSKLPTPKLTRALIEAVEFQQPRRRGPVRPKLRYAHQGGQNPPIIVI
HGNALDAVTDTYKRYLENRFRETFALTGTPLRIEFRSSTNPYADKD

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain

Homologues:

Organism=Escherichia coli, GI87082120, Length=469, Percent_Identity=51.3859275053305, Blast_Score=475, Evalue=1e-135,
Organism=Escherichia coli, GI2367268, Length=94, Percent_Identity=37.2340425531915, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1788919, Length=122, Percent_Identity=31.9672131147541, Blast_Score=63, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17507259, Length=97, Percent_Identity=37.1134020618557, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI115535155, Length=191, Percent_Identity=31.413612565445, Blast_Score=69, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6323665, Length=182, Percent_Identity=31.3186813186813, Blast_Score=78, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DER_BURP8 (B2JIU7)

Other databases:

- EMBL:   CP001043
- RefSeq:   YP_001857644.1
- ProteinModelPortal:   B2JIU7
- SMR:   B2JIU7
- GeneID:   6242907
- GenomeReviews:   CP001043_GR
- KEGG:   bph:Bphy_1416
- HOGENOM:   HBG592135
- OMA:   TRDRTYQ
- ProtClustDB:   PRK00093
- GO:   GO:0005622
- HAMAP:   MF_00195
- InterPro:   IPR003593
- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:3.30.300.20
- PIRSF:   PIRSF006485
- PRINTS:   PR00326
- SMART:   SM00382
- TIGRFAMs:   TIGR03594
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF01926 MMR_HSR1

EC number: NA

Molecular weight: Translated: 49462; Mature: 49462

Theoretical pI: Translated: 9.52; Mature: 9.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPVIALVGRPNVGKSTLFNRLTRSRDALVADLPGLTRDRHYGEGRVGGERPYLVVDTGG
CCCEEEEECCCCCCHHHHHHHHHHCCCCCEECCCCCCCCCCCCCCCCCCCCCEEEEECCC
FEPVAKDGILFEMARQTRQAVEESDVIVFIVDGRNGLAPQDKSIADYLRKTGRPIFLVVN
CCCCCCCCHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCHHHHHHHHHCCCEEEEEEE
KAEGMKYTNVAADFYELGLGDPRAISAAHGDGVTEMINEALDVAYAGQPEESDEEKAQHG
CCCCCEEHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHCC
IKIAIVGRPNVGKSTLVNTLIGEDRVIAFDMPGTTRDSIYVDFERQGKKYTLIDTAGLRK
EEEEEEECCCCCHHHHHHHHCCCCEEEEEECCCCCCCCEEEEEECCCCEEEEEECCCCCH
RGKVFEAIEKFSVVKTLQSISDANVVILLLDARQDISEQDAHIAGFVVEQGRALVVGVNK
HHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCEEEEEEEECCCEEEEECCC
WDGLDPHVRERTKSDLQRKLKFLEFAKFHFISAAEKTGIGPLMRSVDDAYKAAMSKLPTP
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCH
KLTRALIEAVEFQQPRRRGPVRPKLRYAHQGGQNPPIIVIHGNALDAVTDTYKRYLENRF
HHHHHHHHHHHHCCHHHCCCCCCHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHH
RETFALTGTPLRIEFRSSTNPYADKD
HHHEEECCCEEEEEECCCCCCCCCCC
>Mature Secondary Structure
MKPVIALVGRPNVGKSTLFNRLTRSRDALVADLPGLTRDRHYGEGRVGGERPYLVVDTGG
CCCEEEEECCCCCCHHHHHHHHHHCCCCCEECCCCCCCCCCCCCCCCCCCCCEEEEECCC
FEPVAKDGILFEMARQTRQAVEESDVIVFIVDGRNGLAPQDKSIADYLRKTGRPIFLVVN
CCCCCCCCHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCHHHHHHHHHCCCEEEEEEE
KAEGMKYTNVAADFYELGLGDPRAISAAHGDGVTEMINEALDVAYAGQPEESDEEKAQHG
CCCCCEEHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHCC
IKIAIVGRPNVGKSTLVNTLIGEDRVIAFDMPGTTRDSIYVDFERQGKKYTLIDTAGLRK
EEEEEEECCCCCHHHHHHHHCCCCEEEEEECCCCCCCCEEEEEECCCCEEEEEECCCCCH
RGKVFEAIEKFSVVKTLQSISDANVVILLLDARQDISEQDAHIAGFVVEQGRALVVGVNK
HHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCEEEEEEEECCCEEEEECCC
WDGLDPHVRERTKSDLQRKLKFLEFAKFHFISAAEKTGIGPLMRSVDDAYKAAMSKLPTP
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCH
KLTRALIEAVEFQQPRRRGPVRPKLRYAHQGGQNPPIIVIHGNALDAVTDTYKRYLENRF
HHHHHHHHHHHHCCHHHCCCCCCHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHH
RETFALTGTPLRIEFRSSTNPYADKD
HHHEEECCCEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA