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The map label for this gene is yfcB [C]

Identifier: 186476110

GI number: 186476110

Start: 1518262

End: 1519149

Strand: Direct

Name: yfcB [C]

Synonym: Bphy_1352

Alternate gene names: 186476110

Gene position: 1518262-1519149 (Clockwise)

Preceding gene: 186476109

Following gene: 186476111

Centisome position: 43.64

GC content: 63.29

Gene sequence:

>888_bases
ATGACTCATCCGTTTTCCACGGTTCGCGACGTGCTGCGCTACGCGGTGTCGCGCTTCAACCAGGCCGGGCTTGCGTTCGG
CCACGGCTCGTCGAACGCTTATGACGAAGCCGCGTATCTCGTGCTGCACACGCTGCATCTTCCCATCGATCTGCTCGAGC
CGTTTCTCGACGCGCGCCTGACGTCCGAAGAAATCGACTCGGTGCTGAAGGTGGTCGAACGGCGCGCGACAGATCGCGTA
CCCGCCGCCTACATTACGCAGGAAGCGTGGATGCACGGCCATCGCTTCCATGTCGACGAGCGCGTGATCGTGCCGCGTTC
GTTTATCGGCGAACTGCTGCAAGATGGCCTGCAGCCGTATGTCGAGGATCCCGAACAGGTTGGCGCGGTACTCGAACTGT
GCACGGGTTCCGGATGCCTCGCGATTCTCGCGGCATATGCGTTCCCGAATGCCGATATCGACGCCGTCGACCTGTCGCCC
GCCGCACTCGAAGTGGCGACCCGCAATGTCCAGGAGTACGAACTGGAAGAGCGCATTGCGCTGTTCGAAGGCGACCTCTA
TGCACCGCTGCCGGAGCGCCGCTATGACGTGATCATCACAAATCCGCCATACGTCAACGCGGAATCGATGAAGGCGCTGC
CGCCCGAGTACCAGCATGAGCCCGCGATGGCGCTGGCGGGCGGCGCCGACGGAATGGACATCGTGCGCCGCATCATCGCC
AATGCGCGCAACTGGCTGACCGACGACGGCGTGCTGGTGGTCGAGATCGGCAACGAGCGCGCGCATGTCGAAGCGGCGTT
CGGCGGCCTCGATCTCGTGTGGATGTCGACCAGCGCCGGCGACGACAACGTGTTCCTGATACAGGCCAGCGACCTTCCCG
CCAATTGA

Upstream 100 bases:

>100_bases
CAAGATCGACGAACATATCGAAGTCGCACATATCGAGCCGCTCAAGAACGTCTACCGACGCGTGCTCGAACAACTGATAG
CCTGACGGAGGGCCTCGACC

Downstream 100 bases:

>100_bases
TGCCCGCGTGCGGCTGATGGCTGCCTCGCACGACGCACGGTGCCTGTCTGGGCACCGTGCGTCGTGTGCTTTTGGGCGCC
CGCATTCGCTCGCATTCATT

Product: N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 294

Protein sequence:

>295_residues
MTHPFSTVRDVLRYAVSRFNQAGLAFGHGSSNAYDEAAYLVLHTLHLPIDLLEPFLDARLTSEEIDSVLKVVERRATDRV
PAAYITQEAWMHGHRFHVDERVIVPRSFIGELLQDGLQPYVEDPEQVGAVLELCTGSGCLAILAAYAFPNADIDAVDLSP
AALEVATRNVQEYELEERIALFEGDLYAPLPERRYDVIITNPPYVNAESMKALPPEYQHEPAMALAGGADGMDIVRRIIA
NARNWLTDDGVLVVEIGNERAHVEAAFGGLDLVWMSTSAGDDNVFLIQASDLPAN

Sequences:

>Translated_295_residues
MTHPFSTVRDVLRYAVSRFNQAGLAFGHGSSNAYDEAAYLVLHTLHLPIDLLEPFLDARLTSEEIDSVLKVVERRATDRV
PAAYITQEAWMHGHRFHVDERVIVPRSFIGELLQDGLQPYVEDPEQVGAVLELCTGSGCLAILAAYAFPNADIDAVDLSP
AALEVATRNVQEYELEERIALFEGDLYAPLPERRYDVIITNPPYVNAESMKALPPEYQHEPAMALAGGADGMDIVRRIIA
NARNWLTDDGVLVVEIGNERAHVEAAFGGLDLVWMSTSAGDDNVFLIQASDLPAN
>Mature_294_residues
THPFSTVRDVLRYAVSRFNQAGLAFGHGSSNAYDEAAYLVLHTLHLPIDLLEPFLDARLTSEEIDSVLKVVERRATDRVP
AAYITQEAWMHGHRFHVDERVIVPRSFIGELLQDGLQPYVEDPEQVGAVLELCTGSGCLAILAAYAFPNADIDAVDLSPA
ALEVATRNVQEYELEERIALFEGDLYAPLPERRYDVIITNPPYVNAESMKALPPEYQHEPAMALAGGADGMDIVRRIIAN
ARNWLTDDGVLVVEIGNERAHVEAAFGGLDLVWMSTSAGDDNVFLIQASDLPAN

Specific function: Unknown

COG id: COG2890

COG function: function code J; Methylase of polypeptide chain release factors

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI7705409, Length=248, Percent_Identity=30.241935483871, Blast_Score=92, Evalue=6e-19,
Organism=Escherichia coli, GI87082085, Length=290, Percent_Identity=46.551724137931, Blast_Score=286, Evalue=1e-78,
Organism=Escherichia coli, GI1787463, Length=259, Percent_Identity=27.7992277992278, Blast_Score=86, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24582226, Length=190, Percent_Identity=30, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002052
- InterPro:   IPR004556
- InterPro:   IPR017127
- InterPro:   IPR007848 [H]

Pfam domain/function: PF05175 MTS [H]

EC number: =2.1.1.72 [H]

Molecular weight: Translated: 32498; Mature: 32367

Theoretical pI: Translated: 4.24; Mature: 4.24

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHPFSTVRDVLRYAVSRFNQAGLAFGHGSSNAYDEAAYLVLHTLHLPIDLLEPFLDARL
CCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCC
TSEEIDSVLKVVERRATDRVPAAYITQEAWMHGHRFHVDERVIVPRSFIGELLQDGLQPY
CHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCEEECCCEEECCHHHHHHHHHHCCCHH
VEDPEQVGAVLELCTGSGCLAILAAYAFPNADIDAVDLSPAALEVATRNVQEYELEERIA
CCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCEECCCHHHHHHHHCCHHHHHHHHHHH
LFEGDLYAPLPERRYDVIITNPPYVNAESMKALPPEYQHEPAMALAGGADGMDIVRRIIA
HHCCCCCCCCCCCCEEEEECCCCCCCHHHCCCCCCCCCCCCCEEEECCCCCHHHHHHHHH
NARNWLTDDGVLVVEIGNERAHVEAAFGGLDLVWMSTSAGDDNVFLIQASDLPAN
HHHHCCCCCCEEEEEECCCCEEEEEECCCEEEEEEECCCCCCCEEEEEECCCCCC
>Mature Secondary Structure 
THPFSTVRDVLRYAVSRFNQAGLAFGHGSSNAYDEAAYLVLHTLHLPIDLLEPFLDARL
CCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCC
TSEEIDSVLKVVERRATDRVPAAYITQEAWMHGHRFHVDERVIVPRSFIGELLQDGLQPY
CHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCEEECCCEEECCHHHHHHHHHHCCCHH
VEDPEQVGAVLELCTGSGCLAILAAYAFPNADIDAVDLSPAALEVATRNVQEYELEERIA
CCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCEECCCHHHHHHHHCCHHHHHHHHHHH
LFEGDLYAPLPERRYDVIITNPPYVNAESMKALPPEYQHEPAMALAGGADGMDIVRRIIA
HHCCCCCCCCCCCCEEEEECCCCCCCHHHCCCCCCCCCCCCCEEEECCCCCHHHHHHHHH
NARNWLTDDGVLVVEIGNERAHVEAAFGGLDLVWMSTSAGDDNVFLIQASDLPAN
HHHHCCCCCCEEEEEECCCCEEEEEECCCEEEEEEECCCCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10710307 [H]