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The map label for this gene is xylB [H]

Identifier: 186475961

GI number: 186475961

Start: 1342904

End: 1344370

Strand: Reverse

Name: xylB [H]

Synonym: Bphy_1198

Alternate gene names: 186475961

Gene position: 1344370-1342904 (Counterclockwise)

Preceding gene: 186475962

Following gene: 186475960

Centisome position: 38.64

GC content: 64.83

Gene sequence:

>1467_bases
GTGACTTTCCTTGGAATCGACCTCGGGACCTCCGAGGTAAAAGTAATTCTGACCGATGATGCATCCACGACGCTCGCAAC
GAGCGGCGCGCGCCTCGAAGTCTCGCAACCGCATCCGCACTGGTCGGAACAGAGTCCGCAAGCCTGGTGGCAGGCGACGC
TCGATGCCGTTGCTGCCGTGCGAAGCGCGAATCCCGGTGCCTTCGCTGCGCTGCGTGGCATCGGGCTCTCGGGGCAGATG
CACGGCGCGACGCTGATAGATGCGAATGGCGCGGTGCTCAGGCCCGCGATACTCTGGAACGACACACGTGCGTTTGCCGA
ATGCGCGGAGCTGGAAGCGCTCGTGCCCGCGTCGCGTAATATCACCGGCAATCTTGCGATGCCCGGGTTCACCGCACCCA
AACTGCTCTGGCTCGCGAAACACGAACCCGAGGTGTTTCGCGCTGCGTCCAAGGTGCTGCTGCCGAAAGACTATCTCGCG
TGGAAGCTTTCGGGCGATTTTGTCTCCGACATGTCGGATGCGTCGGGTACGTTATGGCTCGACGTCGCGAAGCGCGACTG
GTCCGACGGCATGCTCGCGGCGACGGGATTGACGCGCGCGCACATGCCGCGTCTCGTCGAAGGCAGCGCGCCTGCCGCAC
AGTTGAGTGACGCCTTGCGACGCGATTGGGGCATTGCGGGTCCTGTCGTGCTATGCGGAGGTGCAGGCGACAACGCGGCG
AGCGCGATCGGCACGGGTGTGGCAGATGCGGGCAGTGCATTCCTGTCGCTGGGGACGTCGGGTGTCCTCTTTGCAGGCAC
CGATCGCTTTGCGCCGAATCCCGCTCAAGGCGTGCACGCGTTCTGCCACTGCCTGCCGGCGCGCTGGCATCAGATGAGCG
TGATTTTGTCGGCGGCATCGAGTCTCGGGTGGCTGTCCAAGGTCGTAGGCCGCGAAGTCGGTATCCTGCCTGAACTGGCG
AGCACGGCCAATGCTGCGACGGCGCCTATCTTTCTGCCGTATCTGAGTGGCGAGCGCACGCCGCATAACGATGCGAATGC
GCGCGGTGTCTTTTGGGGGTTGACGGGCGCGCACAGTACGGGCGACCTCGCGTATAGCGTGATGGAAGGCGTTGCGTTCG
CGATGGCCGACGGCTACGCGGCGCTGCAAAGCGCAGGCACTACATTGAAGAGCGCATCGTTTATCGGCGGAGGCTCGCGC
AGCCCTTTCTGGGCGAATCTGTGTGCGACCGCGACGGGCATCACGATGCATCGGCATGAAGGCAGCGACGTCGGCGCGGC
GCTTGGAGCGGCGCGTCTGGCGCGGCTCGCGGTGACGGGCGAGGCCGTCAACCAGGTCTGTGTGGCGCCGCCGACGCTCG
AATCATGCGAGCCCGATCGCGCACAGGCGCCGCTCCTCGCACACAGGCTCGCGCGATATCGGAGCATCTATCAGGCGCTG
AAGACGAGCTTTGCTGAGTCGGCATGA

Upstream 100 bases:

>100_bases
CCTCTCAGACGGTTTCGTGAATGCGTAGCCCCGCGCGCTGGCGTGTGTCGTTTATGTTCAGCATACGGCGTCCACTCATG
CCCACTAGTGAGGACGTGCT

Downstream 100 bases:

>100_bases
TACGCGTACGGCGCGGCGCACCGCGAGGCACGCCGCGCGAGGACGCGTTTTAATTCGGGTCACGCCGAGCTTATTGCAGC
GGCGCGCTGACGGCGAAGTG

Product: xylulokinase

Products: NA

Alternate protein names: Xylulokinase [H]

Number of amino acids: Translated: 488; Mature: 487

Protein sequence:

>488_residues
MTFLGIDLGTSEVKVILTDDASTTLATSGARLEVSQPHPHWSEQSPQAWWQATLDAVAAVRSANPGAFAALRGIGLSGQM
HGATLIDANGAVLRPAILWNDTRAFAECAELEALVPASRNITGNLAMPGFTAPKLLWLAKHEPEVFRAASKVLLPKDYLA
WKLSGDFVSDMSDASGTLWLDVAKRDWSDGMLAATGLTRAHMPRLVEGSAPAAQLSDALRRDWGIAGPVVLCGGAGDNAA
SAIGTGVADAGSAFLSLGTSGVLFAGTDRFAPNPAQGVHAFCHCLPARWHQMSVILSAASSLGWLSKVVGREVGILPELA
STANAATAPIFLPYLSGERTPHNDANARGVFWGLTGAHSTGDLAYSVMEGVAFAMADGYAALQSAGTTLKSASFIGGGSR
SPFWANLCATATGITMHRHEGSDVGAALGAARLARLAVTGEAVNQVCVAPPTLESCEPDRAQAPLLAHRLARYRSIYQAL
KTSFAESA

Sequences:

>Translated_488_residues
MTFLGIDLGTSEVKVILTDDASTTLATSGARLEVSQPHPHWSEQSPQAWWQATLDAVAAVRSANPGAFAALRGIGLSGQM
HGATLIDANGAVLRPAILWNDTRAFAECAELEALVPASRNITGNLAMPGFTAPKLLWLAKHEPEVFRAASKVLLPKDYLA
WKLSGDFVSDMSDASGTLWLDVAKRDWSDGMLAATGLTRAHMPRLVEGSAPAAQLSDALRRDWGIAGPVVLCGGAGDNAA
SAIGTGVADAGSAFLSLGTSGVLFAGTDRFAPNPAQGVHAFCHCLPARWHQMSVILSAASSLGWLSKVVGREVGILPELA
STANAATAPIFLPYLSGERTPHNDANARGVFWGLTGAHSTGDLAYSVMEGVAFAMADGYAALQSAGTTLKSASFIGGGSR
SPFWANLCATATGITMHRHEGSDVGAALGAARLARLAVTGEAVNQVCVAPPTLESCEPDRAQAPLLAHRLARYRSIYQAL
KTSFAESA
>Mature_487_residues
TFLGIDLGTSEVKVILTDDASTTLATSGARLEVSQPHPHWSEQSPQAWWQATLDAVAAVRSANPGAFAALRGIGLSGQMH
GATLIDANGAVLRPAILWNDTRAFAECAELEALVPASRNITGNLAMPGFTAPKLLWLAKHEPEVFRAASKVLLPKDYLAW
KLSGDFVSDMSDASGTLWLDVAKRDWSDGMLAATGLTRAHMPRLVEGSAPAAQLSDALRRDWGIAGPVVLCGGAGDNAAS
AIGTGVADAGSAFLSLGTSGVLFAGTDRFAPNPAQGVHAFCHCLPARWHQMSVILSAASSLGWLSKVVGREVGILPELAS
TANAATAPIFLPYLSGERTPHNDANARGVFWGLTGAHSTGDLAYSVMEGVAFAMADGYAALQSAGTTLKSASFIGGGSRS
PFWANLCATATGITMHRHEGSDVGAALGAARLARLAVTGEAVNQVCVAPPTLESCEPDRAQAPLLAHRLARYRSIYQALK
TSFAESA

Specific function: Unknown

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI42794763, Length=432, Percent_Identity=21.5277777777778, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI41393575, Length=429, Percent_Identity=21.6783216783217, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI189409120, Length=432, Percent_Identity=22.2222222222222, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI4504007, Length=432, Percent_Identity=22.2222222222222, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI18860918, Length=341, Percent_Identity=24.633431085044, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1789987, Length=481, Percent_Identity=51.1434511434511, Blast_Score=452, Evalue=1e-128,
Organism=Escherichia coli, GI1790361, Length=456, Percent_Identity=24.3421052631579, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1790005, Length=500, Percent_Identity=24, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1789168, Length=442, Percent_Identity=23.9819004524887, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1787789, Length=408, Percent_Identity=23.7745098039216, Blast_Score=75, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17535599, Length=436, Percent_Identity=25.2293577981651, Blast_Score=101, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17554530, Length=323, Percent_Identity=23.5294117647059, Blast_Score=74, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6321633, Length=348, Percent_Identity=23.5632183908046, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI17864214, Length=518, Percent_Identity=23.5521235521236, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24654573, Length=449, Percent_Identity=23.3853006681514, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24655555, Length=460, Percent_Identity=22.6086956521739, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24655560, Length=460, Percent_Identity=22.6086956521739, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24655570, Length=460, Percent_Identity=22.6086956521739, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24655574, Length=460, Percent_Identity=22.6086956521739, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24655565, Length=460, Percent_Identity=22.6086956521739, Blast_Score=79, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006000 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.17 [H]

Molecular weight: Translated: 50778; Mature: 50647

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: PS00933 FGGY_KINASES_1 ; PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFLGIDLGTSEVKVILTDDASTTLATSGARLEVSQPHPHWSEQSPQAWWQATLDAVAAV
CEEEEEECCCCCEEEEEECCCCCEEECCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHH
RSANPGAFAALRGIGLSGQMHGATLIDANGAVLRPAILWNDTRAFAECAELEALVPASRN
HCCCCCHHHHHHCCCCCCCCCCEEEEECCCCEEECEEEECCHHHHHHHHHHHHHCCCCCC
ITGNLAMPGFTAPKLLWLAKHEPEVFRAASKVLLPKDYLAWKLSGDFVSDMSDASGTLWL
CCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHCCCCCCEEEEECCCHHHCCCCCCCEEEE
DVAKRDWSDGMLAATGLTRAHMPRLVEGSAPAAQLSDALRRDWGIAGPVVLCGGAGDNAA
EEECCCCCCCEEEECCCHHHHCCHHHCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCHH
SAIGTGVADAGSAFLSLGTSGVLFAGTDRFAPNPAQGVHAFCHCLPARWHQMSVILSAAS
HHHHCCCCHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SLGWLSKVVGREVGILPELASTANAATAPIFLPYLSGERTPHNDANARGVFWGLTGAHST
HHHHHHHHHHHHCCCCHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCEEEEEECCCCCC
GDLAYSVMEGVAFAMADGYAALQSAGTTLKSASFIGGGSRSPFWANLCATATGITMHRHE
HHHHHHHHHHHHHHHHCCHHHHHHCCCHHHCCCCCCCCCCCCHHHHHHHHHHCCEEECCC
GSDVGAALGAARLARLAVTGEAVNQVCVAPPTLESCEPDRAQAPLLAHRLARYRSIYQAL
CCHHHHHHHHHHHHHHHCCHHHHCCEECCCCCCCCCCCCHHCCCHHHHHHHHHHHHHHHH
KTSFAESA
HHHHHCCC
>Mature Secondary Structure 
TFLGIDLGTSEVKVILTDDASTTLATSGARLEVSQPHPHWSEQSPQAWWQATLDAVAAV
EEEEEECCCCCEEEEEECCCCCEEECCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHH
RSANPGAFAALRGIGLSGQMHGATLIDANGAVLRPAILWNDTRAFAECAELEALVPASRN
HCCCCCHHHHHHCCCCCCCCCCEEEEECCCCEEECEEEECCHHHHHHHHHHHHHCCCCCC
ITGNLAMPGFTAPKLLWLAKHEPEVFRAASKVLLPKDYLAWKLSGDFVSDMSDASGTLWL
CCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHCCCCCCEEEEECCCHHHCCCCCCCEEEE
DVAKRDWSDGMLAATGLTRAHMPRLVEGSAPAAQLSDALRRDWGIAGPVVLCGGAGDNAA
EEECCCCCCCEEEECCCHHHHCCHHHCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCHH
SAIGTGVADAGSAFLSLGTSGVLFAGTDRFAPNPAQGVHAFCHCLPARWHQMSVILSAAS
HHHHCCCCHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SLGWLSKVVGREVGILPELASTANAATAPIFLPYLSGERTPHNDANARGVFWGLTGAHST
HHHHHHHHHHHHCCCCHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCEEEEEECCCCCC
GDLAYSVMEGVAFAMADGYAALQSAGTTLKSASFIGGGSRSPFWANLCATATGITMHRHE
HHHHHHHHHHHHHHHHCCHHHHHHCCCHHHCCCCCCCCCCCCHHHHHHHHHHCCEEECCC
GSDVGAALGAARLARLAVTGEAVNQVCVAPPTLESCEPDRAQAPLLAHRLARYRSIYQAL
CCHHHHHHHHHHHHHHHCCHHHHCCEECCCCCCCCCCCCHHCCCHHHHHHHHHHHHHHHH
KTSFAESA
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6320721; 8041620; 9278503 [H]