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The map label for this gene is atpA1 [H]

Identifier: 186475887

GI number: 186475887

Start: 1267888

End: 1269465

Strand: Reverse

Name: atpA1 [H]

Synonym: Bphy_1122

Alternate gene names: 186475887

Gene position: 1269465-1267888 (Counterclockwise)

Preceding gene: 186475888

Following gene: 186475886

Centisome position: 36.49

GC content: 66.54

Gene sequence:

>1578_bases
ATGGACGCGTTTGACGGCACGAACGACGGCTGGCTGGCCTGCAAGCGCAGCGCGCTCGCGGCGATCGAACTGGAAACGCG
CGCGCTCGCGATGGGTCGCGTGGAGCGCATCGCCGACGGCATCGCGTTCGTGTCTGGTTTGCCCGACCTCGCACTCGACG
AGCTGGTCGATATCGAAAATGGCGTGATGGGCTACGTGCACTCGCTGGATGTGGACGTCGCGAGTGTCGTCATGCTCGAC
AACAGCGAGTCCGTTCAGGCGGGCATGCGTGTGACGCCCCGCCATACCGTGCTCGATGTGCCCGTCGGGGAGGCGCTGCT
GGGTCGCGTGGTGGATCCGCTGGGGCGGCCGCTCGACGGCGGCGAACCGGTCAGGACGGAGAGCCGGCTGCCCGTTGAGC
GTCCGGCGCCCGCTATCGTTGAGCGGGACTTCGTCAGTGAGCCGCTCGAGACGGGCGTGCTGATCGTCGATGCGTTGTTT
GCGATCGGACGCGGGCAGCGCGAGCTGATCATCGGCGACCGGGCCACCGGCAAGACCTCGCTCGCCATCGAGACGATCGT
CAATCAGAAACATAGCGACGTGATCTGCGTCTATGTGGCGATCGGTCAACGCGCGATGGCCGTGCAGCGCGCGATCGATG
CGATACGGCAATATGGCGCGCCCGAGCGCTGCGTCTTCGTGGTGGCATCGTCGGCTTCGCCGCCCGGATTGCAATGGGTC
GCGCCGTTTGCCGGCTTCTCGATAGCGGAGTTCTTTCGGGATCGCGGGCAGCACGCGTTGATCGTTGTCGACGATCTGAC
CAGACACGCGGCCACGCATCGCGAGCTCGCGCTGCTTACCCGCGAGCCGCCCGGACGCGAAGCCTATCCGGGCGATATCT
TCTATCTGCATGCGCGTCTGCTCGAACGTGCGGGCCGGCTGTCGGACGGCCTGGGGGGCGGCTCGCTGACGGCGTTGCCG
ATTGCCGAAACCGACGCCGGCAATCTGTCCGCCTACATCCCGACGAACCTGATTTCGATCACAGATGGCCAGATCGTGCT
CGATGCAGGCCTGTTCGCGGCCAACCAGCGACCCGCCGTCGATGTCGGCCTGAGCGTAAGCCGCGTGGGCGGGAAGGCGC
AGTATCCGGCATTGCGCGACGTCGCGGGCCGCTTGCGGCTCGACTACGCGCAGTTTCTCGAACTGGAAGTGTTCAGCCGC
TTCGGCGGACTTGCAGACGCCCGCGTGGTCGCGCAGATCGAGCGTGGAAAACGCATTCGTGCGCTGTTCGCACAGCCGCG
CTTTAGTGCGCTAAGTGCTATCGATCAGGTCGCGTTGCTCTGCGCGCTGGCGGATGGCCTGTTCGACGGCGTGTCCGTCG
AGGCGATCGCACGGGTGCGGCAGCGGCTCGCCACATCGGGAGCCCTTCATCGGCTGACGGGCGGCGCACACGATGCGGAC
GCGCTCCCGGCGCCGCTCGACGACGTGCTGCGTCAGCGCCTGATCGATTTCATGCGGGAAATCGTCGAGCACGCGCAGCC
AGGTGCGGCCGGTGACCTTATCCGTCAGGAGCACGCCGATGACCCGCAGGCTCAGTGA

Upstream 100 bases:

>100_bases
ACGCTGGTCGCGGGACTCGAGCTGGGCGGGCGGCATGGCATCGTGCGCAACAGCTGGCGCGATCAACTGCAACAGATTCA
CAACGGCTTGCTGAACGACG

Downstream 100 bases:

>100_bases
AATCGAAGGCCGGATGGCAACCGCGCATCAACTCGATGCGGTGATCGGCGCAATGCGCGGGATCGCAGCGGCGCGCGAGC
GCGAGGCGCAGGCGCGGCTC

Product: ATP synthase F1 subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha 1; F-ATPase subunit alpha 1 [H]

Number of amino acids: Translated: 525; Mature: 525

Protein sequence:

>525_residues
MDAFDGTNDGWLACKRSALAAIELETRALAMGRVERIADGIAFVSGLPDLALDELVDIENGVMGYVHSLDVDVASVVMLD
NSESVQAGMRVTPRHTVLDVPVGEALLGRVVDPLGRPLDGGEPVRTESRLPVERPAPAIVERDFVSEPLETGVLIVDALF
AIGRGQRELIIGDRATGKTSLAIETIVNQKHSDVICVYVAIGQRAMAVQRAIDAIRQYGAPERCVFVVASSASPPGLQWV
APFAGFSIAEFFRDRGQHALIVVDDLTRHAATHRELALLTREPPGREAYPGDIFYLHARLLERAGRLSDGLGGGSLTALP
IAETDAGNLSAYIPTNLISITDGQIVLDAGLFAANQRPAVDVGLSVSRVGGKAQYPALRDVAGRLRLDYAQFLELEVFSR
FGGLADARVVAQIERGKRIRALFAQPRFSALSAIDQVALLCALADGLFDGVSVEAIARVRQRLATSGALHRLTGGAHDAD
ALPAPLDDVLRQRLIDFMREIVEHAQPGAAGDLIRQEHADDPQAQ

Sequences:

>Translated_525_residues
MDAFDGTNDGWLACKRSALAAIELETRALAMGRVERIADGIAFVSGLPDLALDELVDIENGVMGYVHSLDVDVASVVMLD
NSESVQAGMRVTPRHTVLDVPVGEALLGRVVDPLGRPLDGGEPVRTESRLPVERPAPAIVERDFVSEPLETGVLIVDALF
AIGRGQRELIIGDRATGKTSLAIETIVNQKHSDVICVYVAIGQRAMAVQRAIDAIRQYGAPERCVFVVASSASPPGLQWV
APFAGFSIAEFFRDRGQHALIVVDDLTRHAATHRELALLTREPPGREAYPGDIFYLHARLLERAGRLSDGLGGGSLTALP
IAETDAGNLSAYIPTNLISITDGQIVLDAGLFAANQRPAVDVGLSVSRVGGKAQYPALRDVAGRLRLDYAQFLELEVFSR
FGGLADARVVAQIERGKRIRALFAQPRFSALSAIDQVALLCALADGLFDGVSVEAIARVRQRLATSGALHRLTGGAHDAD
ALPAPLDDVLRQRLIDFMREIVEHAQPGAAGDLIRQEHADDPQAQ
>Mature_525_residues
MDAFDGTNDGWLACKRSALAAIELETRALAMGRVERIADGIAFVSGLPDLALDELVDIENGVMGYVHSLDVDVASVVMLD
NSESVQAGMRVTPRHTVLDVPVGEALLGRVVDPLGRPLDGGEPVRTESRLPVERPAPAIVERDFVSEPLETGVLIVDALF
AIGRGQRELIIGDRATGKTSLAIETIVNQKHSDVICVYVAIGQRAMAVQRAIDAIRQYGAPERCVFVVASSASPPGLQWV
APFAGFSIAEFFRDRGQHALIVVDDLTRHAATHRELALLTREPPGREAYPGDIFYLHARLLERAGRLSDGLGGGSLTALP
IAETDAGNLSAYIPTNLISITDGQIVLDAGLFAANQRPAVDVGLSVSRVGGKAQYPALRDVAGRLRLDYAQFLELEVFSR
FGGLADARVVAQIERGKRIRALFAQPRFSALSAIDQVALLCALADGLFDGVSVEAIARVRQRLATSGALHRLTGGAHDAD
ALPAPLDDVLRQRLIDFMREIVEHAQPGAAGDLIRQEHADDPQAQ

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit [H]

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI50345984, Length=435, Percent_Identity=47.1264367816092, Blast_Score=399, Evalue=1e-111,
Organism=Homo sapiens, GI4757810, Length=435, Percent_Identity=47.1264367816092, Blast_Score=399, Evalue=1e-111,
Organism=Homo sapiens, GI32189394, Length=364, Percent_Identity=24.7252747252747, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI19913426, Length=286, Percent_Identity=25.8741258741259, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI19913428, Length=286, Percent_Identity=25.5244755244755, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI19913424, Length=259, Percent_Identity=28.1853281853282, Blast_Score=76, Evalue=7e-14,
Organism=Escherichia coli, GI1790172, Length=452, Percent_Identity=41.5929203539823, Blast_Score=363, Evalue=1e-101,
Organism=Escherichia coli, GI1788251, Length=352, Percent_Identity=33.2386363636364, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1790170, Length=395, Percent_Identity=26.5822784810127, Blast_Score=106, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI71988063, Length=440, Percent_Identity=46.8181818181818, Blast_Score=405, Evalue=1e-113,
Organism=Caenorhabditis elegans, GI71988080, Length=440, Percent_Identity=46.8181818181818, Blast_Score=404, Evalue=1e-113,
Organism=Caenorhabditis elegans, GI71988074, Length=440, Percent_Identity=43.4090909090909, Blast_Score=363, Evalue=1e-100,
Organism=Caenorhabditis elegans, GI17510931, Length=339, Percent_Identity=26.5486725663717, Blast_Score=101, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI17570191, Length=289, Percent_Identity=26.9896193771626, Blast_Score=99, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI25144756, Length=425, Percent_Identity=25.1764705882353, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17565854, Length=286, Percent_Identity=26.2237762237762, Blast_Score=72, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6319370, Length=433, Percent_Identity=48.4988452655889, Blast_Score=399, Evalue=1e-112,
Organism=Saccharomyces cerevisiae, GI6322581, Length=422, Percent_Identity=24.8815165876777, Blast_Score=107, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6319603, Length=311, Percent_Identity=26.6881028938907, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24658560, Length=508, Percent_Identity=43.503937007874, Blast_Score=399, Evalue=1e-111,
Organism=Drosophila melanogaster, GI281361666, Length=291, Percent_Identity=26.4604810996564, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24646341, Length=291, Percent_Identity=26.4604810996564, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI17136796, Length=291, Percent_Identity=26.4604810996564, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24638766, Length=378, Percent_Identity=23.8095238095238, Blast_Score=96, Evalue=9e-20,
Organism=Drosophila melanogaster, GI28574560, Length=382, Percent_Identity=25.3926701570681, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24583992, Length=256, Percent_Identity=27.34375, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24583988, Length=255, Percent_Identity=27.4509803921569, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24583986, Length=255, Percent_Identity=27.4509803921569, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24583984, Length=255, Percent_Identity=27.4509803921569, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI20129479, Length=254, Percent_Identity=28.740157480315, Blast_Score=70, Evalue=4e-12,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 56270; Mature: 56270

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAFDGTNDGWLACKRSALAAIELETRALAMGRVERIADGIAFVSGLPDLALDELVDIEN
CCCCCCCCCCHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCC
GVMGYVHSLDVDVASVVMLDNSESVQAGMRVTPRHTVLDVPVGEALLGRVVDPLGRPLDG
CHHHHHHHCCCCEEEEEEECCCHHHHCCCEECCCCEEEECCCCHHHHHHHHHHHCCCCCC
GEPVRTESRLPVERPAPAIVERDFVSEPLETGVLIVDALFAIGRGQRELIIGDRATGKTS
CCCCCCCCCCCCCCCCCHHHHHHHHCCHHHCCHHHHHHHHHHCCCCEEEEEECCCCCCHH
LAIETIVNQKHSDVICVYVAIGQRAMAVQRAIDAIRQYGAPERCVFVVASSASPPGLQWV
HHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCEEE
APFAGFSIAEFFRDRGQHALIVVDDLTRHAATHRELALLTREPPGREAYPGDIFYLHARL
CHHCCHHHHHHHHHCCCEEEEEEECHHHHHHHHHHEEEEECCCCCCCCCCCCHHHHHHHH
LERAGRLSDGLGGGSLTALPIAETDAGNLSAYIPTNLISITDGQIVLDAGLFAANQRPAV
HHHHCCCCCCCCCCCEEEEEEECCCCCCEEEECCCCEEEECCCCEEEECCEEECCCCCCE
DVGLSVSRVGGKAQYPALRDVAGRLRLDYAQFLELEVFSRFGGLADARVVAQIERGKRIR
EECCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEE
ALFAQPRFSALSAIDQVALLCALADGLFDGVSVEAIARVRQRLATSGALHRLTGGAHDAD
HHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCHHHHHCCCCCCCC
ALPAPLDDVLRQRLIDFMREIVEHAQPGAAGDLIRQEHADDPQAQ
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MDAFDGTNDGWLACKRSALAAIELETRALAMGRVERIADGIAFVSGLPDLALDELVDIEN
CCCCCCCCCCHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCC
GVMGYVHSLDVDVASVVMLDNSESVQAGMRVTPRHTVLDVPVGEALLGRVVDPLGRPLDG
CHHHHHHHCCCCEEEEEEECCCHHHHCCCEECCCCEEEECCCCHHHHHHHHHHHCCCCCC
GEPVRTESRLPVERPAPAIVERDFVSEPLETGVLIVDALFAIGRGQRELIIGDRATGKTS
CCCCCCCCCCCCCCCCCHHHHHHHHCCHHHCCHHHHHHHHHHCCCCEEEEEECCCCCCHH
LAIETIVNQKHSDVICVYVAIGQRAMAVQRAIDAIRQYGAPERCVFVVASSASPPGLQWV
HHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCEEE
APFAGFSIAEFFRDRGQHALIVVDDLTRHAATHRELALLTREPPGREAYPGDIFYLHARL
CHHCCHHHHHHHHHCCCEEEEEEECHHHHHHHHHHEEEEECCCCCCCCCCCCHHHHHHHH
LERAGRLSDGLGGGSLTALPIAETDAGNLSAYIPTNLISITDGQIVLDAGLFAANQRPAV
HHHHCCCCCCCCCCCEEEEEEECCCCCCEEEECCCCEEEECCCCEEEECCEEECCCCCCE
DVGLSVSRVGGKAQYPALRDVAGRLRLDYAQFLELEVFSRFGGLADARVVAQIERGKRIR
EECCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEE
ALFAQPRFSALSAIDQVALLCALADGLFDGVSVEAIARVRQRLATSGALHRLTGGAHDAD
HHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCHHHHHCCCCCCCC
ALPAPLDDVLRQRLIDFMREIVEHAQPGAAGDLIRQEHADDPQAQ
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA