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The map label for this gene is ppiD [H]

Identifier: 186475780

GI number: 186475780

Start: 1139409

End: 1141337

Strand: Direct

Name: ppiD [H]

Synonym: Bphy_1015

Alternate gene names: 186475780

Gene position: 1139409-1141337 (Clockwise)

Preceding gene: 186475779

Following gene: 186475783

Centisome position: 32.75

GC content: 61.02

Gene sequence:

>1929_bases
ATGCTCGATTTCTTCCGTAATCACCAACGTCTGATGATGTTCATGCTCATCCTGGTCATCTTGCCGGGTTTGGGTTTCGT
CGGTATCCAGGGTTTCCGTGGTTTCTTTGACGAGAGCGCAAACGTCGCGAGCGTCAATGGGCACAAGATCACGCGTGGCG
AGTTCGACAACGCATGGCGCCAGCAGATGGACCGCGCGCGTCAGATGCTCGGCGCGCAGTTCGACGCGAAGATGTTCGAC
ACGCCGGAGCGGCGCAAAGACATGCTCGACGGTCTGATCCAGCAGCGTGTGCTGGCCGACGAAACGCAGCGCCTGCACCT
GACGGTGTCCGACGACGCGCTGCGTCGCGCGTTGCTCGCGGATCCCGTGATCGGATCGTTGAAGAATCCGGACGGCTCGA
TCGACGTGAACAAATACAAAGAACTCCTTGCGATGCAGGGCATCACGCCCGATCAGTACCAGGAGCAGGTGCGCTACAGC
ATGTCGATGCAACAGCTGCCGGCTGCCATCACGCAGACGTCGTTCACGCCGAAGACGCTCGCCCAGCATCTCACCGAACT
CGCCGAGCAGCAGCGCGAAGTGCAGGGTCTCGCGTTCCGTGCAAAGGAGTACGAGTCGAAGGTGCAGCCGACGGATGCGC
AGATCCAAGCTTACTACGATGCCCATCGCGACGACTTCGCGACGCCGGCAACGGCGACTATCCAGTATCTGGTGCTGTCG
CCTGCGACGCTCGCGGCAGCGGCGAATCCCAGCGACGCCGAGCTGAAGAAGTACTACGACGACAATATCGCGCATTTCCG
CACGCCGGGCGAAGTGCGCGCCAGCCACATCCTGATCGTGGCGCCGAAGGATGCAAGCTCAGCCGACAAGGAAAAGGCGA
AACAGAAGGCGCGAGAAGTCCTCGCGCAGGTGAAGGCGCACCCTGACCAGTTCGCGCAACTTGCGCAGCAGAATTCGCAG
GATCCGGGTTCGGCGTCGAAGGGCGGCGATCTCGGCTACTTCAGCCCGGGCATGATCGCAGGCGGCAAGGCGTTCGACGA
CGCCGTGTTCAAGATGAAGAAGGACGAGGTCAGCGATCTGATCCAGTCGGACTTTGGCTATCACATTGTGAAGGTGACGG
ACGTGAGGCCGTCGGTGACAAAGCCGTTCGAGGAAGTGAAAGACTCGATCGCCAAAGATCTCAAGGCGCAACTGGCGACC
AAGGCATTCGGCGACGATTCGGAAGGTTTCACGTCGACGGTCTACGAACAGGCGAAGAGCCTGCAACCGGCTGCCGACAA
ATACAAGCTGCAGATCCAGACCGCGACGGTCACGCCGCGCGCCAACAGCGCGTTGCCGCCGGATAGCCCGCTGAACAATG
CGAAATTCCTTGCTGCGGTTTTCGCGAACGATTCGGCCAAAGACCGCAACAACACGCAGGCAATCGACGTGGGCAACAAC
ACGCTGATCGCAGCGCACGTGACCGACTACAAGCCGGCCGCCGTACCCGCGCTGGCGGTCGTCAGGGACGCCGTGCGTCA
GAAGGTTGTCGCCCAGCGGGCAGCCGATCTCGCGCGAAAGGAGGGCGAAGCGAAGTTGGCCGATCTGCGCAAGTCGAAGT
CGACGGACGGCTTCTCGTCCGCGCTAAAGGTATCGCGCAACGACGCGCAGGGCGTACCGCCTGCTGCATTGGGTGCTATT
TACAAGGCCGATGCGCAAAAACTGCCTGCTTACGTCGGTGTCGATCTGGGCGCGGATGGTTATGCGATCTACCGCGTGAA
TTCGATCGTGCCGCCTGCGCCGACGGATGCGCAGCGTCTGACGTCGGCGCAGCAGCAGATCGCGTCGGTGAATGCGCAAG
CTGAAGCGGAATCCTATCTCGATGCGTTGCGTGCCCGTTCGAAGGTAAAGATTTACGGCTCGCTCGAGAACCCGCAATCG
GGCGAATAA

Upstream 100 bases:

>100_bases
CCGCCAGTATCCTAGAAAGGCGAACTCCGGTTCGCCTTTTTTATTGCCCGCTGTTGTACTATCGGGCGTTCCGTTTTTGG
CATCCGACTTTTGCCTCCTC

Downstream 100 bases:

>100_bases
GCCGTTCGACGGAAGTCGCTGGTTGCGACTTCATTGCCGCCACAACAGAAAGCCCCGCAAGTTGCGGGGCTTTTGTTTCG
CTGCCGAGAAGCGCGAGGAA

Product: PpiC-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: PPIase D; Rotamase D [H]

Number of amino acids: Translated: 642; Mature: 642

Protein sequence:

>642_residues
MLDFFRNHQRLMMFMLILVILPGLGFVGIQGFRGFFDESANVASVNGHKITRGEFDNAWRQQMDRARQMLGAQFDAKMFD
TPERRKDMLDGLIQQRVLADETQRLHLTVSDDALRRALLADPVIGSLKNPDGSIDVNKYKELLAMQGITPDQYQEQVRYS
MSMQQLPAAITQTSFTPKTLAQHLTELAEQQREVQGLAFRAKEYESKVQPTDAQIQAYYDAHRDDFATPATATIQYLVLS
PATLAAAANPSDAELKKYYDDNIAHFRTPGEVRASHILIVAPKDASSADKEKAKQKAREVLAQVKAHPDQFAQLAQQNSQ
DPGSASKGGDLGYFSPGMIAGGKAFDDAVFKMKKDEVSDLIQSDFGYHIVKVTDVRPSVTKPFEEVKDSIAKDLKAQLAT
KAFGDDSEGFTSTVYEQAKSLQPAADKYKLQIQTATVTPRANSALPPDSPLNNAKFLAAVFANDSAKDRNNTQAIDVGNN
TLIAAHVTDYKPAAVPALAVVRDAVRQKVVAQRAADLARKEGEAKLADLRKSKSTDGFSSALKVSRNDAQGVPPAALGAI
YKADAQKLPAYVGVDLGADGYAIYRVNSIVPPAPTDAQRLTSAQQQIASVNAQAEAESYLDALRARSKVKIYGSLENPQS
GE

Sequences:

>Translated_642_residues
MLDFFRNHQRLMMFMLILVILPGLGFVGIQGFRGFFDESANVASVNGHKITRGEFDNAWRQQMDRARQMLGAQFDAKMFD
TPERRKDMLDGLIQQRVLADETQRLHLTVSDDALRRALLADPVIGSLKNPDGSIDVNKYKELLAMQGITPDQYQEQVRYS
MSMQQLPAAITQTSFTPKTLAQHLTELAEQQREVQGLAFRAKEYESKVQPTDAQIQAYYDAHRDDFATPATATIQYLVLS
PATLAAAANPSDAELKKYYDDNIAHFRTPGEVRASHILIVAPKDASSADKEKAKQKAREVLAQVKAHPDQFAQLAQQNSQ
DPGSASKGGDLGYFSPGMIAGGKAFDDAVFKMKKDEVSDLIQSDFGYHIVKVTDVRPSVTKPFEEVKDSIAKDLKAQLAT
KAFGDDSEGFTSTVYEQAKSLQPAADKYKLQIQTATVTPRANSALPPDSPLNNAKFLAAVFANDSAKDRNNTQAIDVGNN
TLIAAHVTDYKPAAVPALAVVRDAVRQKVVAQRAADLARKEGEAKLADLRKSKSTDGFSSALKVSRNDAQGVPPAALGAI
YKADAQKLPAYVGVDLGADGYAIYRVNSIVPPAPTDAQRLTSAQQQIASVNAQAEAESYLDALRARSKVKIYGSLENPQS
GE
>Mature_642_residues
MLDFFRNHQRLMMFMLILVILPGLGFVGIQGFRGFFDESANVASVNGHKITRGEFDNAWRQQMDRARQMLGAQFDAKMFD
TPERRKDMLDGLIQQRVLADETQRLHLTVSDDALRRALLADPVIGSLKNPDGSIDVNKYKELLAMQGITPDQYQEQVRYS
MSMQQLPAAITQTSFTPKTLAQHLTELAEQQREVQGLAFRAKEYESKVQPTDAQIQAYYDAHRDDFATPATATIQYLVLS
PATLAAAANPSDAELKKYYDDNIAHFRTPGEVRASHILIVAPKDASSADKEKAKQKAREVLAQVKAHPDQFAQLAQQNSQ
DPGSASKGGDLGYFSPGMIAGGKAFDDAVFKMKKDEVSDLIQSDFGYHIVKVTDVRPSVTKPFEEVKDSIAKDLKAQLAT
KAFGDDSEGFTSTVYEQAKSLQPAADKYKLQIQTATVTPRANSALPPDSPLNNAKFLAAVFANDSAKDRNNTQAIDVGNN
TLIAAHVTDYKPAAVPALAVVRDAVRQKVVAQRAADLARKEGEAKLADLRKSKSTDGFSSALKVSRNDAQGVPPAALGAI
YKADAQKLPAYVGVDLGADGYAIYRVNSIVPPAPTDAQRLTSAQQQIASVNAQAEAESYLDALRARSKVKIYGSLENPQS
GE

Specific function: PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786645, Length=651, Percent_Identity=26.8817204301075, Blast_Score=186, Evalue=5e-48,
Organism=Escherichia coli, GI1786238, Length=106, Percent_Identity=37.7358490566038, Blast_Score=75, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 70115; Mature: 70115

Theoretical pI: Translated: 7.10; Mature: 7.10

Prosite motif: PS01096 PPIC_PPIASE_1 ; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDFFRNHQRLMMFMLILVILPGLGFVGIQGFRGFFDESANVASVNGHKITRGEFDNAWR
CCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEECCCCEEECCCCCHHHH
QQMDRARQMLGAQFDAKMFDTPERRKDMLDGLIQQRVLADETQRLHLTVSDDALRRALLA
HHHHHHHHHHCCCCCCHHCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHH
DPVIGSLKNPDGSIDVNKYKELLAMQGITPDQYQEQVRYSMSMQQLPAAITQTSFTPKTL
CCCHHCCCCCCCCEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
AQHLTELAEQQREVQGLAFRAKEYESKVQPTDAQIQAYYDAHRDDFATPATATIQYLVLS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHEEC
PATLAAAANPSDAELKKYYDDNIAHFRTPGEVRASHILIVAPKDASSADKEKAKQKAREV
CHHHHHCCCCCHHHHHHHHCCCCHHCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHH
LAQVKAHPDQFAQLAQQNSQDPGSASKGGDLGYFSPGMIAGGKAFDDAVFKMKKDEVSDL
HHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
IQSDFGYHIVKVTDVRPSVTKPFEEVKDSIAKDLKAQLATKAFGDDSEGFTSTVYEQAKS
HHCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHC
LQPAADKYKLQIQTATVTPRANSALPPDSPLNNAKFLAAVFANDSAKDRNNTQAIDVGNN
CCCCCCCEEEEEEEEEECCCCCCCCCCCCCCCCHHEEEEEECCCCCCCCCCCEEEECCCC
TLIAAHVTDYKPAAVPALAVVRDAVRQKVVAQRAADLARKEGEAKLADLRKSKSTDGFSS
EEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHH
ALKVSRNDAQGVPPAALGAIYKADAQKLPAYVGVDLGADGYAIYRVNSIVPPAPTDAQRL
HHHHCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCEEEEEECCCCCCCCCCHHHH
TSAQQQIASVNAQAEAESYLDALRARSKVKIYGSLENPQSGE
HHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCC
>Mature Secondary Structure
MLDFFRNHQRLMMFMLILVILPGLGFVGIQGFRGFFDESANVASVNGHKITRGEFDNAWR
CCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEECCCCEEECCCCCHHHH
QQMDRARQMLGAQFDAKMFDTPERRKDMLDGLIQQRVLADETQRLHLTVSDDALRRALLA
HHHHHHHHHHCCCCCCHHCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHH
DPVIGSLKNPDGSIDVNKYKELLAMQGITPDQYQEQVRYSMSMQQLPAAITQTSFTPKTL
CCCHHCCCCCCCCEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
AQHLTELAEQQREVQGLAFRAKEYESKVQPTDAQIQAYYDAHRDDFATPATATIQYLVLS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHEEC
PATLAAAANPSDAELKKYYDDNIAHFRTPGEVRASHILIVAPKDASSADKEKAKQKAREV
CHHHHHCCCCCHHHHHHHHCCCCHHCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHH
LAQVKAHPDQFAQLAQQNSQDPGSASKGGDLGYFSPGMIAGGKAFDDAVFKMKKDEVSDL
HHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
IQSDFGYHIVKVTDVRPSVTKPFEEVKDSIAKDLKAQLATKAFGDDSEGFTSTVYEQAKS
HHCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHC
LQPAADKYKLQIQTATVTPRANSALPPDSPLNNAKFLAAVFANDSAKDRNNTQAIDVGNN
CCCCCCCEEEEEEEEEECCCCCCCCCCCCCCCCHHEEEEEECCCCCCCCCCCEEEECCCC
TLIAAHVTDYKPAAVPALAVVRDAVRQKVVAQRAADLARKEGEAKLADLRKSKSTDGFSS
EEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHH
ALKVSRNDAQGVPPAALGAIYKADAQKLPAYVGVDLGADGYAIYRVNSIVPPAPTDAQRL
HHHHCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCEEEEEECCCCCCCCCCHHHH
TSAQQQIASVNAQAEAESYLDALRARSKVKIYGSLENPQSGE
HHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]