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The map label for this gene is serB [H]

Identifier: 186475743

GI number: 186475743

Start: 1093273

End: 1094112

Strand: Reverse

Name: serB [H]

Synonym: Bphy_0978

Alternate gene names: 186475743

Gene position: 1094112-1093273 (Counterclockwise)

Preceding gene: 186475748

Following gene: 186475731

Centisome position: 31.45

GC content: 64.17

Gene sequence:

>840_bases
ATGAATCTCGTCATCCAAAGCGTCACCCCAATTGCCGCCGAACACCACAAGCCGCTGCTCGCGCTGTCGCGCGGGGAGAC
GCTCTCCGCCTTCGATCCGTGCGCCGTGCGCATCGACAATGCCGACGTCGGGCAGCGTGCCGACCTCGAGGTCTACTGCA
GCGCGCATGCGCTCGACTATGCGTTCGTCGAAGCGGGCCGCCGTCTGACGGATTTCGGCCTCGTCGCGATGGACATGGAT
TCGACGCTGATCACGATCGAGTGCGTCGACGAAATCGCAGATTTTTGCGGGCTAAAAGCGGAAGTCGCCGCGATCACGGA
AGCGTCGATGCGCGGCGAGATCAAGGACTTCAACGAGAGTCTCACGCGCCGCGTCGCGCTGCTGAAGGGCCTCGATGCGA
GCGCGCTTGAAAAGGTCTATGAGGAGCGGCTGCAACTGTCGCCGGGCGCGGAACAGATGCTGGCGGGCGCGAAGGCTGCG
GGTATGAAGACGCTGCTGGTGTCGGGTGGCTTCACCTTCTTCACCGAGAAACTGCAGACGCGTCTCGGCCTCGATTTCGC
GCGCGCCAACACGCTCGAAATCGTCGACGGCAAGCTGACGGGGCGTGTGCTGGGCGAGATCGTCAACGCCGACGTGAAGG
CCCGCACGCTGCGCGAAGCGTGCGACAAACTCGGCTTTGAACCCGCGCGCGCAATCGCGATGGGCGACGGCTCGAATGAT
CTGAAGATGATGGCGGCGGCGGGCCTGTCCGTCGCATTCCGCGCGAAGCCTGTGGTGCGCGAAGCGGCGAGCGTCGCGTT
CAATCATGTCGGGCTCGACGGCTTGTTGCGGCTGTTCTGA

Upstream 100 bases:

>100_bases
ATAGCCGGGCAACGAGAGCGGAACCGTTACAATAGGCGGATTTTCCGCGCCCGCTTGCTGGCCGTCCATTGCCTGTGCTG
TTGCCACTTCCCGCGTCGAC

Downstream 100 bases:

>100_bases
TCGCAGCTTGCTGCGACGGCACAGGTGAAAAAGCCCGCTCGATATCGAGCGGGCTTGTTGTTCGTGCTTCGATGAAGTGT
GACGCGTTCAGCCCAGCGCG

Product: phosphoserine phosphatase SerB

Products: NA

Alternate protein names: PSP; PSPase; O-phosphoserine phosphohydrolase [H]

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MNLVIQSVTPIAAEHHKPLLALSRGETLSAFDPCAVRIDNADVGQRADLEVYCSAHALDYAFVEAGRRLTDFGLVAMDMD
STLITIECVDEIADFCGLKAEVAAITEASMRGEIKDFNESLTRRVALLKGLDASALEKVYEERLQLSPGAEQMLAGAKAA
GMKTLLVSGGFTFFTEKLQTRLGLDFARANTLEIVDGKLTGRVLGEIVNADVKARTLREACDKLGFEPARAIAMGDGSND
LKMMAAAGLSVAFRAKPVVREAASVAFNHVGLDGLLRLF

Sequences:

>Translated_279_residues
MNLVIQSVTPIAAEHHKPLLALSRGETLSAFDPCAVRIDNADVGQRADLEVYCSAHALDYAFVEAGRRLTDFGLVAMDMD
STLITIECVDEIADFCGLKAEVAAITEASMRGEIKDFNESLTRRVALLKGLDASALEKVYEERLQLSPGAEQMLAGAKAA
GMKTLLVSGGFTFFTEKLQTRLGLDFARANTLEIVDGKLTGRVLGEIVNADVKARTLREACDKLGFEPARAIAMGDGSND
LKMMAAAGLSVAFRAKPVVREAASVAFNHVGLDGLLRLF
>Mature_279_residues
MNLVIQSVTPIAAEHHKPLLALSRGETLSAFDPCAVRIDNADVGQRADLEVYCSAHALDYAFVEAGRRLTDFGLVAMDMD
STLITIECVDEIADFCGLKAEVAAITEASMRGEIKDFNESLTRRVALLKGLDASALEKVYEERLQLSPGAEQMLAGAKAA
GMKTLLVSGGFTFFTEKLQTRLGLDFARANTLEIVDGKLTGRVLGEIVNADVKARTLREACDKLGFEPARAIAMGDGSND
LKMMAAAGLSVAFRAKPVVREAASVAFNHVGLDGLLRLF

Specific function: Unknown

COG id: COG0560

COG function: function code E; Phosphoserine phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serB family [H]

Homologues:

Organism=Homo sapiens, GI46249388, Length=183, Percent_Identity=26.2295081967213, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1790849, Length=219, Percent_Identity=47.945205479452, Blast_Score=183, Evalue=1e-47,
Organism=Saccharomyces cerevisiae, GI6321647, Length=207, Percent_Identity=38.6473429951691, Blast_Score=143, Evalue=2e-35,
Organism=Drosophila melanogaster, GI24661601, Length=195, Percent_Identity=26.6666666666667, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006383
- InterPro:   IPR023190
- InterPro:   IPR004469 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 29939; Mature: 29939

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLVIQSVTPIAAEHHKPLLALSRGETLSAFDPCAVRIDNADVGQRADLEVYCSAHALDY
CCEEECCCCCHHHHCCCCEEEECCCCCCCCCCCEEEEECCCCCCCCCCEEEEECHHHHHH
AFVEAGRRLTDFGLVAMDMDSTLITIECVDEIADFCGLKAEVAAITEASMRGEIKDFNES
HHHHCCCCCHHCCEEEEECCCEEEEHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHH
LTRRVALLKGLDASALEKVYEERLQLSPGAEQMLAGAKAAGMKTLLVSGGFTFFTEKLQT
HHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCEEEEEECCHHHHHHHHHH
RLGLDFARANTLEIVDGKLTGRVLGEIVNADVKARTLREACDKLGFEPARAIAMGDGSND
HHCCHHHCCCEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHEEEECCCCCC
LKMMAAAGLSVAFRAKPVVREAASVAFNHVGLDGLLRLF
HHHHHHCCCEEEECCCHHHHHHHHHHHHHCCHHHHHHCC
>Mature Secondary Structure
MNLVIQSVTPIAAEHHKPLLALSRGETLSAFDPCAVRIDNADVGQRADLEVYCSAHALDY
CCEEECCCCCHHHHCCCCEEEECCCCCCCCCCCEEEEECCCCCCCCCCEEEEECHHHHHH
AFVEAGRRLTDFGLVAMDMDSTLITIECVDEIADFCGLKAEVAAITEASMRGEIKDFNES
HHHHCCCCCHHCCEEEEECCCEEEEHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHH
LTRRVALLKGLDASALEKVYEERLQLSPGAEQMLAGAKAAGMKTLLVSGGFTFFTEKLQT
HHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCEEEEEECCHHHHHHHHHH
RLGLDFARANTLEIVDGKLTGRVLGEIVNADVKARTLREACDKLGFEPARAIAMGDGSND
HHCCHHHCCCEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHEEEECCCCCC
LKMMAAAGLSVAFRAKPVVREAASVAFNHVGLDGLLRLF
HHHHHHCCCEEEECCCHHHHHHHHHHHHHCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]