Definition Burkholderia phymatum STM815 chromosome chromosome 1, complete sequence.
Accession NC_010622
Length 3,479,187

Click here to switch to the map view.

The map label for this gene is gdhII [H]

Identifier: 186475683

GI number: 186475683

Start: 1018980

End: 1019786

Strand: Reverse

Name: gdhII [H]

Synonym: Bphy_0918

Alternate gene names: 186475683

Gene position: 1019786-1018980 (Counterclockwise)

Preceding gene: 186475684

Following gene: 186475673

Centisome position: 29.31

GC content: 64.19

Gene sequence:

>807_bases
ATGGATCTCGGTCTCAAAGACAAGGTGGTTCTGATAACGGGCGGCAGCAAGGGCATCGGACTGGCGTGCGCGCGGGCTTT
CGCGATGGAAGGCGCGAAGGTCGCGATCGTCTCGCGTGATCCCGCCAATCTCGCTCGCGCCCGCGAGCAATTGTCGAGCG
AAGGCTTGCATGTGCATCTGACGCGCGCGGATCTACACGAGCCGCATAGCGCCGCAGACGTCGTCGAGGAAGCGACGGGC
GCCGTCGGCCCGATCGACATCCTCATCAACAGCGCGGGCGCCGCGCGTCGCTACGATCCCGAATCGCTCGACGCGGCCGC
GTTCAAGGCGACGATGGAAGCCAAGTACTTTCCGTATATCTATCCGCAACAGGAGGTGCTGAAGCGTATGGCCGAGCGCG
TCAAATCCGGCGCCGCAAAGGAGCCGGGCACCATTGTCAACATCATCGGCATGGGTGGGAAGATGGCGAGCGACATTCAC
ATCGCAGGCGGTGCCGCCAACGCGGCACTGATGCTCGCGACCGTCGGCCTTGCGCACTATTACGCGCGCTACGGCATTCG
CATCAACGCGATCAATCCCGGCGCGACGCTGACGGATCGCGTCGAAGAAGCGCTGAAACTCGAAGCGTCGCGCGAAGGCA
TCGAGCCCGCCGAAGCGCTAACGCGTGGGGAAGCACGCGTGCCGCTCGGACGTTTCGCGAAACCGGAGGAAATCGCGGAC
GTCGCGCTTTTTCTGGCGAGTCGCCGCGCGAGCTACGTAACGGGCGCGATCGTCCCGATGGATGGAGGCAGCACGCCGCT
GATCTGA

Upstream 100 bases:

>100_bases
CGCGCGCCCCGACAGCCGCGCCCGATTCGCCCCCCGGCATCGCGCACCTCTGCTATCTTTTGACGATATTTCCTTCACTT
CCCTGGTGGCGGTGACGACG

Downstream 100 bases:

>100_bases
CGGCGGCGTGCTGTATCGCGGCTTAAAGGAAGCGGTGGCCGAGCCACCAGCCGGCCGCCGCTAATACGGCGGATGCGGGG
ATCGTCAGCACCCAGGCCCA

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: GLCDH-II [H]

Number of amino acids: Translated: 268; Mature: 268

Protein sequence:

>268_residues
MDLGLKDKVVLITGGSKGIGLACARAFAMEGAKVAIVSRDPANLARAREQLSSEGLHVHLTRADLHEPHSAADVVEEATG
AVGPIDILINSAGAARRYDPESLDAAAFKATMEAKYFPYIYPQQEVLKRMAERVKSGAAKEPGTIVNIIGMGGKMASDIH
IAGGAANAALMLATVGLAHYYARYGIRINAINPGATLTDRVEEALKLEASREGIEPAEALTRGEARVPLGRFAKPEEIAD
VALFLASRRASYVTGAIVPMDGGSTPLI

Sequences:

>Translated_268_residues
MDLGLKDKVVLITGGSKGIGLACARAFAMEGAKVAIVSRDPANLARAREQLSSEGLHVHLTRADLHEPHSAADVVEEATG
AVGPIDILINSAGAARRYDPESLDAAAFKATMEAKYFPYIYPQQEVLKRMAERVKSGAAKEPGTIVNIIGMGGKMASDIH
IAGGAANAALMLATVGLAHYYARYGIRINAINPGATLTDRVEEALKLEASREGIEPAEALTRGEARVPLGRFAKPEEIAD
VALFLASRRASYVTGAIVPMDGGSTPLI
>Mature_268_residues
MDLGLKDKVVLITGGSKGIGLACARAFAMEGAKVAIVSRDPANLARAREQLSSEGLHVHLTRADLHEPHSAADVVEEATG
AVGPIDILINSAGAARRYDPESLDAAAFKATMEAKYFPYIYPQQEVLKRMAERVKSGAAKEPGTIVNIIGMGGKMASDIH
IAGGAANAALMLATVGLAHYYARYGIRINAINPGATLTDRVEEALKLEASREGIEPAEALTRGEARVPLGRFAKPEEIAD
VALFLASRRASYVTGAIVPMDGGSTPLI

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7705925, Length=263, Percent_Identity=30.4182509505703, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI10190704, Length=265, Percent_Identity=31.6981132075472, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI19923817, Length=265, Percent_Identity=27.9245283018868, Blast_Score=88, Evalue=9e-18,
Organism=Homo sapiens, GI4503301, Length=240, Percent_Identity=27.5, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI40254992, Length=261, Percent_Identity=26.4367816091954, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI20149619, Length=235, Percent_Identity=27.6595744680851, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI32483357, Length=262, Percent_Identity=27.8625954198473, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI4503817, Length=175, Percent_Identity=28, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI59889578, Length=243, Percent_Identity=27.1604938271605, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI15277342, Length=276, Percent_Identity=25.3623188405797, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI5031737, Length=279, Percent_Identity=27.5985663082437, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI87082100, Length=264, Percent_Identity=33.3333333333333, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1790717, Length=262, Percent_Identity=27.4809160305344, Blast_Score=100, Evalue=7e-23,
Organism=Escherichia coli, GI1787905, Length=265, Percent_Identity=28.6792452830189, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1787335, Length=262, Percent_Identity=30.5343511450382, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI2367175, Length=260, Percent_Identity=29.2307692307692, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1789208, Length=268, Percent_Identity=27.6119402985075, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1789378, Length=265, Percent_Identity=29.4339622641509, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI87082160, Length=272, Percent_Identity=26.1029411764706, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1786812, Length=279, Percent_Identity=29.7491039426523, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788459, Length=258, Percent_Identity=27.5193798449612, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1789057, Length=263, Percent_Identity=25.4752851711027, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI2367365, Length=267, Percent_Identity=30.3370786516854, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17560150, Length=269, Percent_Identity=31.9702602230483, Blast_Score=104, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17562906, Length=267, Percent_Identity=30.7116104868914, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17562990, Length=265, Percent_Identity=30.188679245283, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17560332, Length=274, Percent_Identity=31.3868613138686, Blast_Score=98, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17538486, Length=269, Percent_Identity=32.3420074349442, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17562908, Length=280, Percent_Identity=28.9285714285714, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI193204405, Length=271, Percent_Identity=31.3653136531365, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17531453, Length=270, Percent_Identity=30, Blast_Score=95, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17562904, Length=267, Percent_Identity=29.2134831460674, Blast_Score=94, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI72000259, Length=267, Percent_Identity=29.5880149812734, Blast_Score=94, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17565030, Length=268, Percent_Identity=32.4626865671642, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17560220, Length=270, Percent_Identity=30.7407407407407, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17559104, Length=273, Percent_Identity=30.4029304029304, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17562910, Length=275, Percent_Identity=29.0909090909091, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI115534694, Length=259, Percent_Identity=27.7992277992278, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17536025, Length=264, Percent_Identity=29.5454545454545, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17563726, Length=267, Percent_Identity=29.2134831460674, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17538480, Length=266, Percent_Identity=28.9473684210526, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17536651, Length=265, Percent_Identity=28.3018867924528, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17551412, Length=277, Percent_Identity=27.7978339350181, Blast_Score=80, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI25147288, Length=259, Percent_Identity=25.8687258687259, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17544670, Length=274, Percent_Identity=27.007299270073, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17561272, Length=247, Percent_Identity=29.5546558704453, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17560676, Length=260, Percent_Identity=24.6153846153846, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71994604, Length=258, Percent_Identity=27.5193798449612, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17555706, Length=263, Percent_Identity=26.2357414448669, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17561402, Length=263, Percent_Identity=28.1368821292776, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71994600, Length=259, Percent_Identity=26.6409266409266, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6324126, Length=274, Percent_Identity=27.007299270073, Blast_Score=69, Evalue=8e-13,
Organism=Drosophila melanogaster, GI23397609, Length=265, Percent_Identity=31.3207547169811, Blast_Score=111, Evalue=6e-25,
Organism=Drosophila melanogaster, GI21355319, Length=267, Percent_Identity=28.4644194756554, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24639444, Length=271, Percent_Identity=31.3653136531365, Blast_Score=85, Evalue=4e-17,
Organism=Drosophila melanogaster, GI28571526, Length=263, Percent_Identity=28.8973384030418, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24643142, Length=265, Percent_Identity=29.0566037735849, Blast_Score=84, Evalue=8e-17,
Organism=Drosophila melanogaster, GI21357041, Length=267, Percent_Identity=29.2134831460674, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24644337, Length=262, Percent_Identity=30.9160305343511, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24644339, Length=263, Percent_Identity=26.615969581749, Blast_Score=77, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.47 [H]

Molecular weight: Translated: 28186; Mature: 28186

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MDLGLKDKVVLITGGSKGIGLACARAFAMEGAKVAIVSRDPANLARAREQLSSEGLHVHL
CCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHCCCCEEEE
TRADLHEPHSAADVVEEATGAVGPIDILINSAGAARRYDPESLDAAAFKATMEAKYFPYI
ECCCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCEE
YPQQEVLKRMAERVKSGAAKEPGTIVNIIGMGGKMASDIHIAGGAANAALMLATVGLAHY
CCHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCEEEECCCCHHHHHHHHHHHHHH
YARYGIRINAINPGATLTDRVEEALKLEASREGIEPAEALTRGEARVPLGRFAKPEEIAD
HHHHCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCHHHHHH
VALFLASRRASYVTGAIVPMDGGSTPLI
HHHHHHHCCCCHHEEEEEECCCCCCCCC
>Mature Secondary Structure
MDLGLKDKVVLITGGSKGIGLACARAFAMEGAKVAIVSRDPANLARAREQLSSEGLHVHL
CCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHCCCCEEEE
TRADLHEPHSAADVVEEATGAVGPIDILINSAGAARRYDPESLDAAAFKATMEAKYFPYI
ECCCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCEE
YPQQEVLKRMAERVKSGAAKEPGTIVNIIGMGGKMASDIHIAGGAANAALMLATVGLAHY
CCHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCEEEECCCCHHHHHHHHHHHHHH
YARYGIRINAINPGATLTDRVEEALKLEASREGIEPAEALTRGEARVPLGRFAKPEEIAD
HHHHCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCHHHHHH
VALFLASRRASYVTGAIVPMDGGSTPLI
HHHHHHHCCCCHHEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA