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The map label for this gene is dnaQ [H]

Identifier: 186475632

GI number: 186475632

Start: 967768

End: 968517

Strand: Reverse

Name: dnaQ [H]

Synonym: Bphy_0867

Alternate gene names: 186475632

Gene position: 968517-967768 (Counterclockwise)

Preceding gene: 186475633

Following gene: 186475631

Centisome position: 27.84

GC content: 61.07

Gene sequence:

>750_bases
ATGCGTCAAATCATCCTCGATACGGAAACGACAGGACTGAATGCGAGAACGGGCGACCGCATCATCGAAATCGGCTGCGT
CGAGCTGGTGAATCGCCGGCTGACGGGCAACAACCTGCACTTCTACATCAATCCGGAGCGCGACAGCGATCCGGGCGCAT
TGGCCGTCCATGGCTTGACGACGGAATTCCTGAGCGACAAGCCCAAATTCGCCGAGATCGCCGACACGCTGCGCGACTTC
ATCCAGGACGCGGAACTCATCATTCACAACGCGCCCTTCGACATCGGCTTTCTCGACGCCGAGTTCGCGCTGCTCGGGCT
GCCGCCTTTTTCGCAGTATTGCGGCGAGGTGATCGACACGCTCGTGCGCGCGAAGTCGATGTTCCCGGGAAAGCGCAATT
CGCTCGACGCGCTGTGCGACCGCTTCGGCATCAGCAACGCACATCGCACGCTGCACGGCGCACTGCTCGACTCGGAACTG
CTAGCCGAGGTCTACCTCGCGATGACACGCGGCCAGGAAAGCCTCGTGATTGACATGCTCGGCGAAACGGCAGCGGACGA
CGCAGGCGGCGCGAAGCGCGTGATGCTCGACACGCTCGAACTGATCGTGCTAGCGGCGACGGACGACGAGCTCGCCGAAC
ATGAAGCATTGCTCGACGGTCTCGATAAATCGCTGAAGGGAACGAGCGTGTGGCGCACGCATCCGACCACGGAAGATGCG
TCCGCAACAGCTGATGCGCAAATTGCTTAA

Upstream 100 bases:

>100_bases
ATCGCGGCGTGGCTTCGCTGGCAGATCTCTGACGCGCGCCCGCGGCTTGTTTCGAAGCATCCTATTTTTTTCACGCATCA
ACACAGGCAGGCAACACGAT

Downstream 100 bases:

>100_bases
GAAAGTGCTTGTCGAACTCCGAAAGTCCTGACATAATGCACAGCTCTTCGGGTGGTTAGCTCAGCGGTAGAGCACTGCCT
TCACACGGCAGGGGTCACTG

Product: DNA polymerase III subunit epsilon

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MRQIILDTETTGLNARTGDRIIEIGCVELVNRRLTGNNLHFYINPERDSDPGALAVHGLTTEFLSDKPKFAEIADTLRDF
IQDAELIIHNAPFDIGFLDAEFALLGLPPFSQYCGEVIDTLVRAKSMFPGKRNSLDALCDRFGISNAHRTLHGALLDSEL
LAEVYLAMTRGQESLVIDMLGETAADDAGGAKRVMLDTLELIVLAATDDELAEHEALLDGLDKSLKGTSVWRTHPTTEDA
SATADAQIA

Sequences:

>Translated_249_residues
MRQIILDTETTGLNARTGDRIIEIGCVELVNRRLTGNNLHFYINPERDSDPGALAVHGLTTEFLSDKPKFAEIADTLRDF
IQDAELIIHNAPFDIGFLDAEFALLGLPPFSQYCGEVIDTLVRAKSMFPGKRNSLDALCDRFGISNAHRTLHGALLDSEL
LAEVYLAMTRGQESLVIDMLGETAADDAGGAKRVMLDTLELIVLAATDDELAEHEALLDGLDKSLKGTSVWRTHPTTEDA
SATADAQIA
>Mature_249_residues
MRQIILDTETTGLNARTGDRIIEIGCVELVNRRLTGNNLHFYINPERDSDPGALAVHGLTTEFLSDKPKFAEIADTLRDF
IQDAELIIHNAPFDIGFLDAEFALLGLPPFSQYCGEVIDTLVRAKSMFPGKRNSLDALCDRFGISNAHRTLHGALLDSEL
LAEVYLAMTRGQESLVIDMLGETAADDAGGAKRVMLDTLELIVLAATDDELAEHEALLDGLDKSLKGTSVWRTHPTTEDA
SATADAQIA

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease [H]

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786409, Length=238, Percent_Identity=55.4621848739496, Blast_Score=256, Evalue=1e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006054
- InterPro:   IPR006309
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 27137; Mature: 27137

Theoretical pI: Translated: 4.30; Mature: 4.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQIILDTETTGLNARTGDRIIEIGCVELVNRRLTGNNLHFYINPERDSDPGALAVHGLT
CCEEEEECCCCCCCCCCCCEEEEHHHHHHHHHCCCCCCEEEEECCCCCCCCCEEEEECCH
TEFLSDKPKFAEIADTLRDFIQDAELIIHNAPFDIGFLDAEFALLGLPPFSQYCGEVIDT
HHHHCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCEEECCCEEEECCCCHHHHHHHHHHH
LVRAKSMFPGKRNSLDALCDRFGISNAHRTLHGALLDSELLAEVYLAMTRGQESLVIDML
HHHHHHCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHH
GETAADDAGGAKRVMLDTLELIVLAATDDELAEHEALLDGLDKSLKGTSVWRTHPTTEDA
CCCCCCCCCCCHHHHHHHEEEEEEECCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCC
SATADAQIA
CCCCCCCCC
>Mature Secondary Structure
MRQIILDTETTGLNARTGDRIIEIGCVELVNRRLTGNNLHFYINPERDSDPGALAVHGLT
CCEEEEECCCCCCCCCCCCEEEEHHHHHHHHHCCCCCCEEEEECCCCCCCCCEEEEECCH
TEFLSDKPKFAEIADTLRDFIQDAELIIHNAPFDIGFLDAEFALLGLPPFSQYCGEVIDT
HHHHCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCEEECCCEEEECCCCHHHHHHHHHHH
LVRAKSMFPGKRNSLDALCDRFGISNAHRTLHGALLDSELLAEVYLAMTRGQESLVIDML
HHHHHHCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHH
GETAADDAGGAKRVMLDTLELIVLAATDDELAEHEALLDGLDKSLKGTSVWRTHPTTEDA
CCCCCCCCCCCHHHHHHHEEEEEEECCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCC
SATADAQIA
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3023634; 6316347; 3540531; 9278503; 1575709 [H]