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The map label for this gene is zraR [H]

Identifier: 186475548

GI number: 186475548

Start: 877513

End: 879000

Strand: Reverse

Name: zraR [H]

Synonym: Bphy_0783

Alternate gene names: 186475548

Gene position: 879000-877513 (Counterclockwise)

Preceding gene: 186475549

Following gene: 186475547

Centisome position: 25.26

GC content: 67.07

Gene sequence:

>1488_bases
GTGCGCGAATCTTCTCATTTGAGTTCCGTTACCCCGCTCGCCGGCTCCCGGCTGCGTCTTGCCGCCTCGCGCGGATCGGA
AACGTCCGCTGCGCGCCCCGCAGCCGTCGACGCGCCGCGCGGCGCCGCGCCCCGGGCACGCGCACGTGTGCTCCTGTACG
CGGCCCGCACGCCCGACGACGCGCTCGTCGAGCAACTGAAGAGCCGCGGCTGGAGCGTGCTCGTCGCGCGCTCGGCACAC
GATATCGGCAAGCTCATCAAGCCCGCGACCTTGTGCGCGGGCATCGTCGACATGGCGAGCTTTCCGGCGCGCGATCTGCC
GGGGCTCGAGGCGGGCCTGCGCCAGCAGCAGGTCGGCTGGATCGCGCTGGCGAATCCCGAAAGGCTCGCGGACCCCGCCG
TGCGGCGGCTGATCCGCCACTATTGCTTCGACTACGTGAAGCTTCCCGTCGCACACGCGACAATCGACTACCTGGTCGGC
CATGCATACGGAATGATCCATCTCAGCGACGCCGACCTGCCGCCCGACACGACGGCCGTCAGCGACGATGAGATGGTCGG
CACCTGCGAAGCGATGCAGCAGTTGTTCCGCACGATCCGCAAGGTCGCGAACACGGATGCGAGCGTGTTCATCTCGGGCG
AATCGGGCACGGGTAAGGAACTGACGGCGTTGGCGATCCACGAGCGTTCGCCGCGGCGCAAGGCGCCGTTCGTCCCGATC
AACTGCGGTGCGATTGCGCATCACCTGCTGCAGTCGGAGTTGTTCGGCTACGAGCGCGGCGCGTTCACGGGCGCGAACCA
GCGCAAGATCGGGCGCGTCGAGGCGGCCAACGGCGGCACGCTGTTTCTCGACGAAATCGGCGACCTGCCGATGGAGAGCC
AGGCGAGCCTGTTGCGCTTCCTGCAAGAAGGCAAGATCGAGCGTCTGGGCGGCCACGAATCGATTTCCGTCGACGTGCGT
ATCATCTCGGCGACCCACGTCGATCTGGAAGGCGCGATGAGCGAAGGTCGCTTCCGCCAGGACCTGTTTCACCGGCTGTG
CGTGCTGCGCGTCGACGAGCCGCCGCTGCGCGCGCGCGGCAAGGACATCGAACTACTCGCGCATCACATTCTCGGCAAGT
TCAAGACGGACAGCGCGCGCAAGATTCGCGGCTTCGCGCCGTCGGCGATCGAGGCGATGTACAGCTACCACTGGCCCGGC
AATGTGCGCGAGCTGATCAACCGGGTGCGGCGCGCGATCGTGATGGCGGAGAGCAAGCTGATCTCCGCCGAGGATCTGGA
CCTCGCGCAGTTCAGCGAGCAGCAGACGATGAGTCTCGCGCAGGCGCGCGAAGTGGCCGAGAAGCGCGCGATCGAGGCCG
CGCTGCTGCGGCATCGGCACCGTCTCAACGAGGCGGCAGTGGATCTAGGCATTTCGCGCGTGACGCTGTACCGGCTGATG
AGCACGCATGGATTGCGGGACGCGTCGGGTGACGACAAGGGCGAATGA

Upstream 100 bases:

>100_bases
GAATTCGAGCGCGATCGGCATGACGCCCGACGGGCCGAACTATGTCACTGGCCTGCGCTTTCCCTACACCTTTTGACGTG
ACACCGATACGAGGCAGATC

Downstream 100 bases:

>100_bases
CGGGCGTTTGCGTGCACTTGCACGGGTGATTGCTTTTCGTTTCGGCTCGCGTTTCGGCAAGCGTTCGGCTGGACGGCAGG
CTGTCGGGTAGAATCGGCGT

Product: sigma-54 dependent trancsriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 495; Mature: 495

Protein sequence:

>495_residues
MRESSHLSSVTPLAGSRLRLAASRGSETSAARPAAVDAPRGAAPRARARVLLYAARTPDDALVEQLKSRGWSVLVARSAH
DIGKLIKPATLCAGIVDMASFPARDLPGLEAGLRQQQVGWIALANPERLADPAVRRLIRHYCFDYVKLPVAHATIDYLVG
HAYGMIHLSDADLPPDTTAVSDDEMVGTCEAMQQLFRTIRKVANTDASVFISGESGTGKELTALAIHERSPRRKAPFVPI
NCGAIAHHLLQSELFGYERGAFTGANQRKIGRVEAANGGTLFLDEIGDLPMESQASLLRFLQEGKIERLGGHESISVDVR
IISATHVDLEGAMSEGRFRQDLFHRLCVLRVDEPPLRARGKDIELLAHHILGKFKTDSARKIRGFAPSAIEAMYSYHWPG
NVRELINRVRRAIVMAESKLISAEDLDLAQFSEQQTMSLAQAREVAEKRAIEAALLRHRHRLNEAAVDLGISRVTLYRLM
STHGLRDASGDDKGE

Sequences:

>Translated_495_residues
MRESSHLSSVTPLAGSRLRLAASRGSETSAARPAAVDAPRGAAPRARARVLLYAARTPDDALVEQLKSRGWSVLVARSAH
DIGKLIKPATLCAGIVDMASFPARDLPGLEAGLRQQQVGWIALANPERLADPAVRRLIRHYCFDYVKLPVAHATIDYLVG
HAYGMIHLSDADLPPDTTAVSDDEMVGTCEAMQQLFRTIRKVANTDASVFISGESGTGKELTALAIHERSPRRKAPFVPI
NCGAIAHHLLQSELFGYERGAFTGANQRKIGRVEAANGGTLFLDEIGDLPMESQASLLRFLQEGKIERLGGHESISVDVR
IISATHVDLEGAMSEGRFRQDLFHRLCVLRVDEPPLRARGKDIELLAHHILGKFKTDSARKIRGFAPSAIEAMYSYHWPG
NVRELINRVRRAIVMAESKLISAEDLDLAQFSEQQTMSLAQAREVAEKRAIEAALLRHRHRLNEAAVDLGISRVTLYRLM
STHGLRDASGDDKGE
>Mature_495_residues
MRESSHLSSVTPLAGSRLRLAASRGSETSAARPAAVDAPRGAAPRARARVLLYAARTPDDALVEQLKSRGWSVLVARSAH
DIGKLIKPATLCAGIVDMASFPARDLPGLEAGLRQQQVGWIALANPERLADPAVRRLIRHYCFDYVKLPVAHATIDYLVG
HAYGMIHLSDADLPPDTTAVSDDEMVGTCEAMQQLFRTIRKVANTDASVFISGESGTGKELTALAIHERSPRRKAPFVPI
NCGAIAHHLLQSELFGYERGAFTGANQRKIGRVEAANGGTLFLDEIGDLPMESQASLLRFLQEGKIERLGGHESISVDVR
IISATHVDLEGAMSEGRFRQDLFHRLCVLRVDEPPLRARGKDIELLAHHILGKFKTDSARKIRGFAPSAIEAMYSYHWPG
NVRELINRVRRAIVMAESKLISAEDLDLAQFSEQQTMSLAQAREVAEKRAIEAALLRHRHRLNEAAVDLGISRVTLYRLM
STHGLRDASGDDKGE

Specific function: Member of the two-component regulatory system zraS/zraR. When activated by zraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=345, Percent_Identity=44.6376811594203, Blast_Score=271, Evalue=1e-73,
Organism=Escherichia coli, GI1788550, Length=366, Percent_Identity=41.5300546448087, Blast_Score=259, Evalue=2e-70,
Organism=Escherichia coli, GI1790299, Length=376, Percent_Identity=40.1595744680851, Blast_Score=248, Evalue=6e-67,
Organism=Escherichia coli, GI1789233, Length=325, Percent_Identity=43.0769230769231, Blast_Score=240, Evalue=1e-64,
Organism=Escherichia coli, GI1788905, Length=295, Percent_Identity=43.728813559322, Blast_Score=239, Evalue=3e-64,
Organism=Escherichia coli, GI87082117, Length=233, Percent_Identity=50.6437768240343, Blast_Score=236, Evalue=2e-63,
Organism=Escherichia coli, GI87082152, Length=333, Percent_Identity=40.8408408408408, Blast_Score=218, Evalue=6e-58,
Organism=Escherichia coli, GI1786524, Length=319, Percent_Identity=42.6332288401254, Blast_Score=217, Evalue=2e-57,
Organism=Escherichia coli, GI1789087, Length=238, Percent_Identity=44.9579831932773, Blast_Score=215, Evalue=6e-57,
Organism=Escherichia coli, GI87081872, Length=335, Percent_Identity=36.4179104477612, Blast_Score=204, Evalue=1e-53,
Organism=Escherichia coli, GI1787583, Length=327, Percent_Identity=31.4984709480122, Blast_Score=168, Evalue=7e-43,
Organism=Escherichia coli, GI87081858, Length=294, Percent_Identity=32.312925170068, Blast_Score=142, Evalue=7e-35,
Organism=Escherichia coli, GI1789828, Length=245, Percent_Identity=34.6938775510204, Blast_Score=124, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 54265; Mature: 54265

Theoretical pI: Translated: 8.70; Mature: 8.70

Prosite motif: PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRESSHLSSVTPLAGSRLRLAASRGSETSAARPAAVDAPRGAAPRARARVLLYAARTPDD
CCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCH
ALVEQLKSRGWSVLVARSAHDIGKLIKPATLCAGIVDMASFPARDLPGLEAGLRQQQVGW
HHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCE
IALANPERLADPAVRRLIRHYCFDYVKLPVAHATIDYLVGHAYGMIHLSDADLPPDTTAV
EEECCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCC
SDDEMVGTCEAMQQLFRTIRKVANTDASVFISGESGTGKELTALAIHERSPRRKAPFVPI
CCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEEEECCCCCCCCCEEEE
NCGAIAHHLLQSELFGYERGAFTGANQRKIGRVEAANGGTLFLDEIGDLPMESQASLLRF
CHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCEEEEECCCCCCCCHHHHHHHH
LQEGKIERLGGHESISVDVRIISATHVDLEGAMSEGRFRQDLFHRLCVLRVDEPPLRARG
HHCCCHHHCCCCCEEEEEEEEEEEEEECHHHHHHCCHHHHHHHHHHHEEECCCCCCCCCC
KDIELLAHHILGKFKTDSARKIRGFAPSAIEAMYSYHWPGNVRELINRVRRAIVMAESKL
CHHHHHHHHHHHCCCCCCHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
ISAEDLDLAQFSEQQTMSLAQAREVAEKRAIEAALLRHRHRLNEAAVDLGISRVTLYRLM
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH
STHGLRDASGDDKGE
HHCCCCCCCCCCCCC
>Mature Secondary Structure
MRESSHLSSVTPLAGSRLRLAASRGSETSAARPAAVDAPRGAAPRARARVLLYAARTPDD
CCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCH
ALVEQLKSRGWSVLVARSAHDIGKLIKPATLCAGIVDMASFPARDLPGLEAGLRQQQVGW
HHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCE
IALANPERLADPAVRRLIRHYCFDYVKLPVAHATIDYLVGHAYGMIHLSDADLPPDTTAV
EEECCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCC
SDDEMVGTCEAMQQLFRTIRKVANTDASVFISGESGTGKELTALAIHERSPRRKAPFVPI
CCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEEEECCCCCCCCCEEEE
NCGAIAHHLLQSELFGYERGAFTGANQRKIGRVEAANGGTLFLDEIGDLPMESQASLLRF
CHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCEEEEECCCCCCCCHHHHHHHH
LQEGKIERLGGHESISVDVRIISATHVDLEGAMSEGRFRQDLFHRLCVLRVDEPPLRARG
HHCCCHHHCCCCCEEEEEEEEEEEEEECHHHHHHCCHHHHHHHHHHHEEECCCCCCCCCC
KDIELLAHHILGKFKTDSARKIRGFAPSAIEAMYSYHWPGNVRELINRVRRAIVMAESKL
CHHHHHHHHHHHCCCCCCHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
ISAEDLDLAQFSEQQTMSLAQAREVAEKRAIEAALLRHRHRLNEAAVDLGISRVTLYRLM
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH
STHGLRDASGDDKGE
HHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]