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The map label for this gene is hutH [H]

Identifier: 186475461

GI number: 186475461

Start: 782434

End: 784029

Strand: Direct

Name: hutH [H]

Synonym: Bphy_0696

Alternate gene names: 186475461

Gene position: 782434-784029 (Clockwise)

Preceding gene: 186475460

Following gene: 186475462

Centisome position: 22.49

GC content: 67.23

Gene sequence:

>1596_bases
ATGTCGGAACATGATCTGATCGACGATGCACACGCGCATGCTGCACGCGCCGCCGCGCCGCGCACGGTGGTGGTCGGCGG
ACGCAAGCTGTCGATCGAAGAGGTCGTCGCGATTGCGACAGGGCGCGCACAGGTCGCACTGAGCGGCGATCCCGCATGGC
GTTCCCGTATCCAGCGCGGCGCAGATTTTCTGCGTCGTCATCTTGCTGCGGGCGAAACGGTGTACGGCGTGAACACGGGT
TATGGCGACGCGTGTGTGGTCGATGTGCCGATGGACCTCGTCGAGGCATTGCCGCTGCAGCTCACGCGCTATCACGGCTG
TGGAATGGGCGCGTATCTCGACGACGCACAAACGCTCGCCGTAATCGCCGCACGTCTGAACTCGCTGGCGCATGGATTTT
CAGGCGTGCGCCCGGTGCTGCTCGAACGGCTCGCCGATCTCGTCAACCATCGTGTGCTGCCGCGCATTCCATCGGAAGGG
TCGGTGGGCGCAAGCGGCGACCTGACGCCGCTGTCGTATGTGGCGGCAGCGCTCGTCGGCGAACGCGACGTGATGTTCGA
CGGCACGCTGCGCGACGCCGCCGGCGTGTGGACGCAACTCGGGCACGCACCGTTGACGCTCGCGCCGAAGGAAGGCCTCG
CGCTGATGAACGGCACAGCCGTGATGACGGGTCTCGCCTGTCTCGCGTTTGCGCGCGCCGAACACCTCGCGCGTCTTGCC
GCGCGTTTGACGGCGCTGTCGACGGTCGCGCTCGACGGCCGCGCCGCGCACTTCGACGCGATGATCTTCGAAGCGAAGCC
GCACGCGGGTCAGGCCGATGCCGCCGCATGGATCCGCGCGGATCTCGCCGGCCGCGACGATACGCCGGGCCATCGTCTGC
AGGATCGCTATTCGATCCGCTGCGCGCCGCATGTGATCGGCGTCGCCGTCGATGCGCTGTCGTGGGTGCGCCGCGACGTC
GAGAACGAGCTCAATAGCGCGAACGACAATCCGCTGATCGACCCCGACGGCGAGCGCGTGCTGCACGGCGGCAACTTCTA
CGGCGGCCATATTGCGTTTGCAATGGACGCGTTGAAGACGGCCGTTGCCAATCTCGCCGATTTGATGGACCGGCAACTCG
CGCTGATCGTCGACGACAAGTTCAGCAACGGCTTGCCGCGCAACCTGACGGGCGCGACGTCGGCGCGTGCGCCGATCAAT
CACGGCTTCAAGGCGGTGCAGATCTCGTCGTCGGCATGGACGGCGGAGGCGCTGAAGCACACGATGCCCGCGAGCGTGTT
CTCGCGCTCGACGGAAGCGCACAATCAGGACAAGGTCAGCATGGGCACGATCGCCGCACGCGACTGCCTGCGCGTGCTGG
ACCTGACGGAGCAGGTGGCAGCCGCGCATACGCTCGCCGCCGTGCAGGCGCTGACGTTGCGCGTGCGCCTCAACGAAGCG
ACGCCCGTGCCCGCGCCGTTGCGCGCATTCGCGGACGGCGTCGCGGCGCTGTCGCCGTTCGTCGACGAAGACCGCGCGCT
CGAAAGCGATCTGCGCGCGTTGACCGCGCGCATCGCCGATTGCGCGTTGATGGAAGGAGGCGCGCATCGTGCATGA

Upstream 100 bases:

>100_bases
CACTATTGCCGCAAGGCGCCGTATCAATGGTTCAATTTCTTCGATTTCTGGGCGCGTCCCCGAAAAGCGATAACGGGTGC
AATCCCGAACGGAGACGCGA

Downstream 100 bases:

>100_bases
ACGCCACTCCACACTGAAAGCGAGCGCGATCGTCGAAGTCCCGTTTCACGACGTCGATGCGATGAACGTCTGCTGGCACG
GCCATTATCTGAAGTACTTC

Product: histidine ammonia-lyase

Products: NA

Alternate protein names: Histidase [H]

Number of amino acids: Translated: 531; Mature: 530

Protein sequence:

>531_residues
MSEHDLIDDAHAHAARAAAPRTVVVGGRKLSIEEVVAIATGRAQVALSGDPAWRSRIQRGADFLRRHLAAGETVYGVNTG
YGDACVVDVPMDLVEALPLQLTRYHGCGMGAYLDDAQTLAVIAARLNSLAHGFSGVRPVLLERLADLVNHRVLPRIPSEG
SVGASGDLTPLSYVAAALVGERDVMFDGTLRDAAGVWTQLGHAPLTLAPKEGLALMNGTAVMTGLACLAFARAEHLARLA
ARLTALSTVALDGRAAHFDAMIFEAKPHAGQADAAAWIRADLAGRDDTPGHRLQDRYSIRCAPHVIGVAVDALSWVRRDV
ENELNSANDNPLIDPDGERVLHGGNFYGGHIAFAMDALKTAVANLADLMDRQLALIVDDKFSNGLPRNLTGATSARAPIN
HGFKAVQISSSAWTAEALKHTMPASVFSRSTEAHNQDKVSMGTIAARDCLRVLDLTEQVAAAHTLAAVQALTLRVRLNEA
TPVPAPLRAFADGVAALSPFVDEDRALESDLRALTARIADCALMEGGAHRA

Sequences:

>Translated_531_residues
MSEHDLIDDAHAHAARAAAPRTVVVGGRKLSIEEVVAIATGRAQVALSGDPAWRSRIQRGADFLRRHLAAGETVYGVNTG
YGDACVVDVPMDLVEALPLQLTRYHGCGMGAYLDDAQTLAVIAARLNSLAHGFSGVRPVLLERLADLVNHRVLPRIPSEG
SVGASGDLTPLSYVAAALVGERDVMFDGTLRDAAGVWTQLGHAPLTLAPKEGLALMNGTAVMTGLACLAFARAEHLARLA
ARLTALSTVALDGRAAHFDAMIFEAKPHAGQADAAAWIRADLAGRDDTPGHRLQDRYSIRCAPHVIGVAVDALSWVRRDV
ENELNSANDNPLIDPDGERVLHGGNFYGGHIAFAMDALKTAVANLADLMDRQLALIVDDKFSNGLPRNLTGATSARAPIN
HGFKAVQISSSAWTAEALKHTMPASVFSRSTEAHNQDKVSMGTIAARDCLRVLDLTEQVAAAHTLAAVQALTLRVRLNEA
TPVPAPLRAFADGVAALSPFVDEDRALESDLRALTARIADCALMEGGAHRA
>Mature_530_residues
SEHDLIDDAHAHAARAAAPRTVVVGGRKLSIEEVVAIATGRAQVALSGDPAWRSRIQRGADFLRRHLAAGETVYGVNTGY
GDACVVDVPMDLVEALPLQLTRYHGCGMGAYLDDAQTLAVIAARLNSLAHGFSGVRPVLLERLADLVNHRVLPRIPSEGS
VGASGDLTPLSYVAAALVGERDVMFDGTLRDAAGVWTQLGHAPLTLAPKEGLALMNGTAVMTGLACLAFARAEHLARLAA
RLTALSTVALDGRAAHFDAMIFEAKPHAGQADAAAWIRADLAGRDDTPGHRLQDRYSIRCAPHVIGVAVDALSWVRRDVE
NELNSANDNPLIDPDGERVLHGGNFYGGHIAFAMDALKTAVANLADLMDRQLALIVDDKFSNGLPRNLTGATSARAPINH
GFKAVQISSSAWTAEALKHTMPASVFSRSTEAHNQDKVSMGTIAARDCLRVLDLTEQVAAAHTLAAVQALTLRVRLNEAT
PVPAPLRAFADGVAALSPFVDEDRALESDLRALTARIADCALMEGGAHRA

Specific function: Unknown

COG id: COG2986

COG function: function code E; Histidine ammonia-lyase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PAL/histidase family [H]

Homologues:

Organism=Homo sapiens, GI4504333, Length=504, Percent_Identity=34.3253968253968, Blast_Score=267, Evalue=2e-71,
Organism=Caenorhabditis elegans, GI17567831, Length=527, Percent_Identity=33.3965844402277, Blast_Score=243, Evalue=3e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005921
- InterPro:   IPR008948
- InterPro:   IPR001106
- InterPro:   IPR022313 [H]

Pfam domain/function: PF00221 PAL [H]

EC number: =4.3.1.3 [H]

Molecular weight: Translated: 56215; Mature: 56084

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: PS00488 PAL_HISTIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEHDLIDDAHAHAARAAAPRTVVVGGRKLSIEEVVAIATGRAQVALSGDPAWRSRIQRG
CCCCCCCCHHHHHHHHHCCCCEEEECCCEECHHHHHHHCCCCEEEEECCCHHHHHHHHHH
ADFLRRHLAAGETVYGVNTGYGDACVVDVPMDLVEALPLQLTRYHGCGMGAYLDDAQTLA
HHHHHHHHHCCCEEEECCCCCCCEEEEECCHHHHHHCCHHHHHHCCCCCCCHHCCHHHHH
VIAARLNSLAHGFSGVRPVLLERLADLVNHRVLPRIPSEGSVGASGDLTPLSYVAAALVG
HHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHC
ERDVMFDGTLRDAAGVWTQLGHAPLTLAPKEGLALMNGTAVMTGLACLAFARAEHLARLA
CCCEEECCCHHHHHHHHHHCCCCCEEECCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHH
ARLTALSTVALDGRAAHFDAMIFEAKPHAGQADAAAWIRADLAGRDDTPGHRLQDRYSIR
HHHHHHHHHEECCCCHHEEEEEEECCCCCCCCHHHHHHHHHCCCCCCCCCCHHCCCCEEE
CAPHVIGVAVDALSWVRRDVENELNSANDNPLIDPDGERVLHGGNFYGGHIAFAMDALKT
ECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHH
AVANLADLMDRQLALIVDDKFSNGLPRNLTGATSARAPINHGFKAVQISSSAWTAEALKH
HHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHCCCEEEEECCCHHHHHHHHH
TMPASVFSRSTEAHNQDKVSMGTIAARDCLRVLDLTEQVAAAHTLAAVQALTLRVRLNEA
HCCHHHHHCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCC
TPVPAPLRAFADGVAALSPFVDEDRALESDLRALTARIADCALMEGGAHRA
CCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SEHDLIDDAHAHAARAAAPRTVVVGGRKLSIEEVVAIATGRAQVALSGDPAWRSRIQRG
CCCCCCCHHHHHHHHHCCCCEEEECCCEECHHHHHHHCCCCEEEEECCCHHHHHHHHHH
ADFLRRHLAAGETVYGVNTGYGDACVVDVPMDLVEALPLQLTRYHGCGMGAYLDDAQTLA
HHHHHHHHHCCCEEEECCCCCCCEEEEECCHHHHHHCCHHHHHHCCCCCCCHHCCHHHHH
VIAARLNSLAHGFSGVRPVLLERLADLVNHRVLPRIPSEGSVGASGDLTPLSYVAAALVG
HHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHC
ERDVMFDGTLRDAAGVWTQLGHAPLTLAPKEGLALMNGTAVMTGLACLAFARAEHLARLA
CCCEEECCCHHHHHHHHHHCCCCCEEECCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHH
ARLTALSTVALDGRAAHFDAMIFEAKPHAGQADAAAWIRADLAGRDDTPGHRLQDRYSIR
HHHHHHHHHEECCCCHHEEEEEEECCCCCCCCHHHHHHHHHCCCCCCCCCCHHCCCCEEE
CAPHVIGVAVDALSWVRRDVENELNSANDNPLIDPDGERVLHGGNFYGGHIAFAMDALKT
ECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHH
AVANLADLMDRQLALIVDDKFSNGLPRNLTGATSARAPINHGFKAVQISSSAWTAEALKH
HHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHCCCEEEEECCCHHHHHHHHH
TMPASVFSRSTEAHNQDKVSMGTIAARDCLRVLDLTEQVAAAHTLAAVQALTLRVRLNEA
HCCHHHHHCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCC
TPVPAPLRAFADGVAALSPFVDEDRALESDLRALTARIADCALMEGGAHRA
CCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA