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The map label for this gene is yggV [C]

Identifier: 186475432

GI number: 186475432

Start: 752148

End: 752771

Strand: Reverse

Name: yggV [C]

Synonym: Bphy_0666

Alternate gene names: 186475432

Gene position: 752771-752148 (Counterclockwise)

Preceding gene: 186475433

Following gene: 186475431

Centisome position: 21.64

GC content: 65.71

Gene sequence:

>624_bases
GTGAGTGATCGTCAGGACAACGCGCTGCGCAAGATCGTGCTGGCGTCGAACAACGCGGGCAAGCTGCGCGAGTTCGCCGC
GCTGTTCGGTACGGCGGGCATCGAGCTCATTCCGCAAGGCGCGCTGAACGTGCCGGAAGCGGAAGAGCCGCATCCCACGT
TCGTCGAAAACGCGCTGACGAAGGCGCGTCACGCATCGAAGCTGACGGGCCTGCCCGCGATCGCCGATGATTCCGGCCTG
TGCGTGCGCGCGCTGCGCGGCGCGCCCGGCGTATATTCGGCGCGCTATGCGCAGCTTGCAGGCGGCGAGAAGAGCGACGC
TGCAAATAACGCGCGTCTCGTCGAGCAGTTGAAAGACACGAGCGACCGGCGGGCGTATTACTTCTGCGTGCTCGCGCTTG
TGCGCCATGCGGGTGACCCGGAGCCGCTGATCGCCGAAGGCCGCTGGCACGGCGAAATGCTCGATGCGCCGCGTGGCAAG
AATGGCTTCGGCTACGACCCCTACTTCTTCCTGCCCGCGCTGAACGCAACGGCGGCCGAACTGGAGCCTGCCGTGAAGAA
CGCGACGAGTCATCGCGCACTTGCGCTGCAGCAGTTGTTTGCGCGACTGAAGGAGGAAGCGTGA

Upstream 100 bases:

>100_bases
GTGCCCTTCTCGCGCGATGAAATGAACAAGCTGCTCGATCTCGCGCAAGCCGGCATTGCGACGCTGATCGCGAAGCAGAA
GGAAGCATTGGAGTCCAAGG

Downstream 100 bases:

>100_bases
GTCAGGCATCGACGGCCGGCGTCAACGTCGTCAAGGCGTTCACCTCGCCTGGCAGCATCCATTTGACTTCGCTGCCGCCG
CTCGCGCTGTACGTGCATTT

Product: putative deoxyribonucleotide triphosphate pyrophosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase [H]

Number of amino acids: Translated: 207; Mature: 206

Protein sequence:

>207_residues
MSDRQDNALRKIVLASNNAGKLREFAALFGTAGIELIPQGALNVPEAEEPHPTFVENALTKARHASKLTGLPAIADDSGL
CVRALRGAPGVYSARYAQLAGGEKSDAANNARLVEQLKDTSDRRAYYFCVLALVRHAGDPEPLIAEGRWHGEMLDAPRGK
NGFGYDPYFFLPALNATAAELEPAVKNATSHRALALQQLFARLKEEA

Sequences:

>Translated_207_residues
MSDRQDNALRKIVLASNNAGKLREFAALFGTAGIELIPQGALNVPEAEEPHPTFVENALTKARHASKLTGLPAIADDSGL
CVRALRGAPGVYSARYAQLAGGEKSDAANNARLVEQLKDTSDRRAYYFCVLALVRHAGDPEPLIAEGRWHGEMLDAPRGK
NGFGYDPYFFLPALNATAAELEPAVKNATSHRALALQQLFARLKEEA
>Mature_206_residues
SDRQDNALRKIVLASNNAGKLREFAALFGTAGIELIPQGALNVPEAEEPHPTFVENALTKARHASKLTGLPAIADDSGLC
VRALRGAPGVYSARYAQLAGGEKSDAANNARLVEQLKDTSDRRAYYFCVLALVRHAGDPEPLIAEGRWHGEMLDAPRGKN
GFGYDPYFFLPALNATAAELEPAVKNATSHRALALQQLFARLKEEA

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions [H]

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family [H]

Homologues:

Organism=Homo sapiens, GI15626999, Length=200, Percent_Identity=33, Blast_Score=81, Evalue=7e-16,
Organism=Homo sapiens, GI31657144, Length=168, Percent_Identity=33.9285714285714, Blast_Score=69, Evalue=4e-12,
Organism=Escherichia coli, GI1789324, Length=198, Percent_Identity=50, Blast_Score=193, Evalue=8e-51,
Organism=Caenorhabditis elegans, GI17556833, Length=192, Percent_Identity=31.25, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI19920712, Length=190, Percent_Identity=31.0526315789474, Blast_Score=78, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002637
- InterPro:   IPR020922 [H]

Pfam domain/function: PF01725 Ham1p_like [H]

EC number: =3.6.1.15 [H]

Molecular weight: Translated: 22337; Mature: 22206

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDRQDNALRKIVLASNNAGKLREFAALFGTAGIELIPQGALNVPEAEEPHPTFVENALT
CCCCHHHHHHEEEEECCCCHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCCHHHHHHHHH
KARHASKLTGLPAIADDSGLCVRALRGAPGVYSARYAQLAGGEKSDAANNARLVEQLKDT
HHHHHHHHCCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHCC
SDRRAYYFCVLALVRHAGDPEPLIAEGRWHGEMLDAPRGKNGFGYDPYFFLPALNATAAE
CCCHHHHHHHHHHHHHCCCCCCEEECCCCCCHHCCCCCCCCCCCCCCEEEEECCCCHHHH
LEPAVKNATSHRALALQQLFARLKEEA
HHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SDRQDNALRKIVLASNNAGKLREFAALFGTAGIELIPQGALNVPEAEEPHPTFVENALT
CCCHHHHHHEEEEECCCCHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCCHHHHHHHHH
KARHASKLTGLPAIADDSGLCVRALRGAPGVYSARYAQLAGGEKSDAANNARLVEQLKDT
HHHHHHHHCCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHCC
SDRRAYYFCVLALVRHAGDPEPLIAEGRWHGEMLDAPRGKNGFGYDPYFFLPALNATAAE
CCCHHHHHHHHHHHHHCCCCCCEEECCCCCCHHCCCCCCCCCCCCCCEEEEECCCCHHHH
LEPAVKNATSHRALALQQLFARLKEEA
HHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA