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The map label for this gene is minC

Identifier: 186475421

GI number: 186475421

Start: 741479

End: 742327

Strand: Direct

Name: minC

Synonym: Bphy_0655

Alternate gene names: 186475421

Gene position: 741479-742327 (Clockwise)

Preceding gene: 186475420

Following gene: 186475422

Centisome position: 21.31

GC content: 65.84

Gene sequence:

>849_bases
ATGTCGCCCAGGAAATCGCCATTCTTTGAACTGCGCAGTGGGGCGGTCGACACGCTGCTGTTTGTCGTCAAGACGACCGA
CCTCGCTGAAATGCGTGCCGAACTGACCCGGCGCTTCGAGGCGACGCCCGAATTCTTCGCGAACGATACCGTCGCGATCG
ACGTGCGCCGTCTTGCAGAAAACGAGCGTGTGCCGCTTGCGGAGATCGCCACGCTGCTGGGCAGCGTGCGCATGCGTCCC
ATCGGCGTCGTTGCCGACAGCACGCAGCATGGATGGGCGAACGAAGCCGGACTGCCGCTGCTCGATGCGCGCGACCCGCG
CGGCGGCAGGAACCATGGTGACGAAGCGGGCGAAGAAGCGCCCGGCAAGCCGGGCGCCGTGGCGCCGAAGCCTGATGCGG
CACCGCCGGCCGATGCAGCATCGAATGCGCAAGTGCAGATGCAGCTGCCGATTGCCGCTCAGGAAGACGGCGCGCCCCAG
GCGGCAGCCGAGGGCGTGCGCATCGGCACCTCGTCGCAGACGACGGTGATCGACAAGCCGCTGCGCTCGGGGCAGCGCAT
CTACGCGAAGGGCGATCTCGTCGTGCTCGGCATGGTGAGCAACGGCGCCGAAGTGATCGCGGAAGGCAACATTCATATTT
ATGCGCCGTTGCGCGGCCGCGCGCTTGCGGGCGTGCACGGCAATCACGACGCGCGCATTTTCTGCACGTGTCTCGAAGCG
GAACTGATCTCGATCGCGGGCATCTACCGGACGACCGAGAACCCGCTGCCAGCCGACGTGCACGGCAAGCCGGTGCAGAT
CTGGCTCGACGAAGAAAAGCTGATGATCGAACCGCTGCGGCTCACCTGA

Upstream 100 bases:

>100_bases
GCGCACGCGGCATTTTTCTGTCGCGTGAAGACTTATTGGCAAAAAAGCTCACCGTTCGCCTGGACGCCTGTAAAATACGC
AAAATTTTTTGCCGAACGCT

Downstream 100 bases:

>100_bases
TGCGTGCGCCGCACACGCAGTGCGTGTGTCGCGCGATGGAACTCCCGCCGGACTCAATAGACGAATTGACGAACACAAGG
TAAAGGGTAATGGCAAAAAT

Product: septum formation inhibitor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 282; Mature: 281

Protein sequence:

>282_residues
MSPRKSPFFELRSGAVDTLLFVVKTTDLAEMRAELTRRFEATPEFFANDTVAIDVRRLAENERVPLAEIATLLGSVRMRP
IGVVADSTQHGWANEAGLPLLDARDPRGGRNHGDEAGEEAPGKPGAVAPKPDAAPPADAASNAQVQMQLPIAAQEDGAPQ
AAAEGVRIGTSSQTTVIDKPLRSGQRIYAKGDLVVLGMVSNGAEVIAEGNIHIYAPLRGRALAGVHGNHDARIFCTCLEA
ELISIAGIYRTTENPLPADVHGKPVQIWLDEEKLMIEPLRLT

Sequences:

>Translated_282_residues
MSPRKSPFFELRSGAVDTLLFVVKTTDLAEMRAELTRRFEATPEFFANDTVAIDVRRLAENERVPLAEIATLLGSVRMRP
IGVVADSTQHGWANEAGLPLLDARDPRGGRNHGDEAGEEAPGKPGAVAPKPDAAPPADAASNAQVQMQLPIAAQEDGAPQ
AAAEGVRIGTSSQTTVIDKPLRSGQRIYAKGDLVVLGMVSNGAEVIAEGNIHIYAPLRGRALAGVHGNHDARIFCTCLEA
ELISIAGIYRTTENPLPADVHGKPVQIWLDEEKLMIEPLRLT
>Mature_281_residues
SPRKSPFFELRSGAVDTLLFVVKTTDLAEMRAELTRRFEATPEFFANDTVAIDVRRLAENERVPLAEIATLLGSVRMRPI
GVVADSTQHGWANEAGLPLLDARDPRGGRNHGDEAGEEAPGKPGAVAPKPDAAPPADAASNAQVQMQLPIAAQEDGAPQA
AAEGVRIGTSSQTTVIDKPLRSGQRIYAKGDLVVLGMVSNGAEVIAEGNIHIYAPLRGRALAGVHGNHDARIFCTCLEAE
LISIAGIYRTTENPLPADVHGKPVQIWLDEEKLMIEPLRLT

Specific function: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize ftsZ filaments that have formed before they mature into polar Z rings. Prevents ftsZ polymerization

COG id: COG0850

COG function: function code D; Septum formation inhibitor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the minC family

Homologues:

Organism=Escherichia coli, GI1787424, Length=149, Percent_Identity=45.6375838926174, Blast_Score=114, Evalue=6e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MINC_BURP8 (B2JEG8)

Other databases:

- EMBL:   CP001043
- RefSeq:   YP_001856891.1
- ProteinModelPortal:   B2JEG8
- GeneID:   6242154
- GenomeReviews:   CP001043_GR
- KEGG:   bph:Bphy_0655
- HOGENOM:   HBG399077
- OMA:   PEFFAND
- ProtClustDB:   PRK01973
- HAMAP:   MF_00267
- InterPro:   IPR016098
- InterPro:   IPR013033
- InterPro:   IPR007874
- InterPro:   IPR005526
- Gene3D:   G3DSA:2.160.20.70
- TIGRFAMs:   TIGR01222

Pfam domain/function: PF03775 MinC_C; PF05209 MinC_N; SSF63848 MinC_C

EC number: NA

Molecular weight: Translated: 30172; Mature: 30040

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPRKSPFFELRSGAVDTLLFVVKTTDLAEMRAELTRRFEATPEFFANDTVAIDVRRLAE
CCCCCCCHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHCCCCHHHCCCEEEEEEHHHCC
NERVPLAEIATLLGSVRMRPIGVVADSTQHGWANEAGLPLLDARDPRGGRNHGDEAGEEA
CCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCC
PGKPGAVAPKPDAAPPADAASNAQVQMQLPIAAQEDGAPQAAAEGVRIGTSSQTTVIDKP
CCCCCCCCCCCCCCCCCCCCCCCEEEEEECEEECCCCCCHHHHCCEEECCCCCCEEEECH
LRSGQRIYAKGDLVVLGMVSNGAEVIAEGNIHIYAPLRGRALAGVHGNHDARIFCTCLEA
HCCCCEEEEECCEEEEEEECCCCEEEEECCEEEEECCCCCEEECCCCCCCCEEEEEEEHH
ELISIAGIYRTTENPLPADVHGKPVQIWLDEEKLMIEPLRLT
HHHHHHHEEECCCCCCCCCCCCCEEEEEECCCCEEEEEECCC
>Mature Secondary Structure 
SPRKSPFFELRSGAVDTLLFVVKTTDLAEMRAELTRRFEATPEFFANDTVAIDVRRLAE
CCCCCCHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHCCCCHHHCCCEEEEEEHHHCC
NERVPLAEIATLLGSVRMRPIGVVADSTQHGWANEAGLPLLDARDPRGGRNHGDEAGEEA
CCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCC
PGKPGAVAPKPDAAPPADAASNAQVQMQLPIAAQEDGAPQAAAEGVRIGTSSQTTVIDKP
CCCCCCCCCCCCCCCCCCCCCCCEEEEEECEEECCCCCCHHHHCCEEECCCCCCEEEECH
LRSGQRIYAKGDLVVLGMVSNGAEVIAEGNIHIYAPLRGRALAGVHGNHDARIFCTCLEA
HCCCCEEEEECCEEEEEEECCCCEEEEECCEEEEECCCCCEEECCCCCCCCEEEEEEEHH
ELISIAGIYRTTENPLPADVHGKPVQIWLDEEKLMIEPLRLT
HHHHHHHEEECCCCCCCCCCCCCEEEEEECCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA