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The map label for this gene is flbA [H]

Identifier: 186475405

GI number: 186475405

Start: 719663

End: 721291

Strand: Direct

Name: flbA [H]

Synonym: Bphy_0639

Alternate gene names: 186475405

Gene position: 719663-721291 (Clockwise)

Preceding gene: 186475404

Following gene: 186475407

Centisome position: 20.68

GC content: 63.78

Gene sequence:

>1629_bases
ATGTACGGTGATTGGCAGAATTCCCAGGCCAAAGTTGATCGTTATTCATCCGCCGTCTCCCAGTATGGCAACGCACGCTT
CGATGCCGCGCTCGCACTGCTCGAACCGCTGCTGACATCGCATACCGCCGATGCGCACGTTTTCAATCTGGCCGCCGCGT
GCTGCCTGTCGCTGGATCGTTTGGACCATGCGGAGATCTACTGGCGGCGAGCAATCGCACTGAAGCCCGATTACTGCGAC
GCGCACAACAACCTCGGCGTCGTGCTGAAAGAGTCGGGCCGCCTGGACGAAGCAAAGGCCTGCTATCACAAGGCACTCTC
GATTTCGCCGACACACGCGGGCGCTTACGTGAACCTCGGGCGGCTCCATGCGCAACTAGGCCGTTCGGACGAGGCTGAAT
CCTGCTATCTGCGCGCGCTGGAACTTCAGCCCGGCGACGGCGATGTCTACGTGAATCTTGGCGTGCTGTATCAGGAGCAA
ATGCGCTTGCGTGAAGCCGAGGCCGCGTACAAGAGCGCGATTGCCGCCAATCCGCGCGACGCCAAGGCCCATTTCAATCT
CGGCGTGGTGCTCAAGATGCAGCATCGCTTCGCCGAAGCGGAAGCGTCGTACCGGCACACGCTTGCGCTTCGGCCCGACT
ACTTCGAGGTGAAGATCAACCTCGCGCATCTGCTGCTCAACGTGGGTCGCCTGGAGGAGGGATGGGCGCTGTTCGAGACA
CGCTACGAGCGCGCGTGGCCGGCGCGTAAGGTCGCGCCACCGCCCGTCGATTTCCCGCTCTGGCGCGGCGAGCCGCTCGC
GGGCAAATCGTTGCTCGTGTGGCCGGAGCAAGGGCACGGAGACAGTCTGCAATTCTGCCGCTATCTGCCGATGCTCAAGG
CGCTCGGCCTCGCGAAGCTGAGCCTCGCGTGTTCGCCTGCGTTGCGCAGCCTGCTCGAAACCATCGAGGGCGTCGACGCA
TGCATTCCACTCGACGGCGAACACGATATTCCGAAGCACGACTACGTGTGCCTGACGATGAGCCTGCCCCATCGGCTCGG
GACGACGCTTACGACCATTCCGGCCGGGACGCCGTATCTGAGCGTGCCGCCGGCATACGCCGCCCAATGGAAAGGACGGT
TGCCAGAAGGCGCGCGCAGGGTAGGCCTCGTCTGGGCCGGCGATCCACGTCCCGATCAACCGGCGATCAACGCTGTCGAC
CGCCGCCGCTCGCTCGACGCGCGCGCGTATCTCCCGCTGCTGCGCGTGCCGGGCATCACGTTCATCAGTCTGCAAAAAGG
CGCGTTGACGCAGCCGCAAATCGACACACTACCGCTGGAATTTCGCCCGTTCGATCCGATGCACGGGGTTCACGAGTTCG
CCGACACCGCCGCGATCATCGAGCAACTCGACCTCGTGATTTCCGTCGATACCTCCATCGCGCATCTGGCCGGTGCGTTG
AACAGGCCGACGTGGGTTCTGTCGCGCTACGACGGCTGCTGGCGCTGGCTACATGATCGCGACGACACGCCGTGGTATCC
GCGCACGCGTCTGTTCCGTCAGACGCAGCCAGGCGAGTGGGACGGAGTGATCGAGCGCGTGAGAATCGCGCTCGAACAAT
GGCCGGCTCACGAACGCGCGCCGACCTGA

Upstream 100 bases:

>100_bases
GTACGCTACATGGGCCTCGGCGCGATGTCGATCAAGATTCCTGGATAAATCAGGGAGCGCGCCGGCAGTCTTTCCTAATC
CGTCTCCGCAGGATCAAATC

Downstream 100 bases:

>100_bases
AGGTCTCACACGAAAGCGCTTACGCATATGCCTGCTTGCGCACGGACACGAACGCGAGATAGAACACCGCGCCGATTACG
AGCGCGGGCAGCGTTGCACC

Product: TPR repeat-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 542; Mature: 542

Protein sequence:

>542_residues
MYGDWQNSQAKVDRYSSAVSQYGNARFDAALALLEPLLTSHTADAHVFNLAAACCLSLDRLDHAEIYWRRAIALKPDYCD
AHNNLGVVLKESGRLDEAKACYHKALSISPTHAGAYVNLGRLHAQLGRSDEAESCYLRALELQPGDGDVYVNLGVLYQEQ
MRLREAEAAYKSAIAANPRDAKAHFNLGVVLKMQHRFAEAEASYRHTLALRPDYFEVKINLAHLLLNVGRLEEGWALFET
RYERAWPARKVAPPPVDFPLWRGEPLAGKSLLVWPEQGHGDSLQFCRYLPMLKALGLAKLSLACSPALRSLLETIEGVDA
CIPLDGEHDIPKHDYVCLTMSLPHRLGTTLTTIPAGTPYLSVPPAYAAQWKGRLPEGARRVGLVWAGDPRPDQPAINAVD
RRRSLDARAYLPLLRVPGITFISLQKGALTQPQIDTLPLEFRPFDPMHGVHEFADTAAIIEQLDLVISVDTSIAHLAGAL
NRPTWVLSRYDGCWRWLHDRDDTPWYPRTRLFRQTQPGEWDGVIERVRIALEQWPAHERAPT

Sequences:

>Translated_542_residues
MYGDWQNSQAKVDRYSSAVSQYGNARFDAALALLEPLLTSHTADAHVFNLAAACCLSLDRLDHAEIYWRRAIALKPDYCD
AHNNLGVVLKESGRLDEAKACYHKALSISPTHAGAYVNLGRLHAQLGRSDEAESCYLRALELQPGDGDVYVNLGVLYQEQ
MRLREAEAAYKSAIAANPRDAKAHFNLGVVLKMQHRFAEAEASYRHTLALRPDYFEVKINLAHLLLNVGRLEEGWALFET
RYERAWPARKVAPPPVDFPLWRGEPLAGKSLLVWPEQGHGDSLQFCRYLPMLKALGLAKLSLACSPALRSLLETIEGVDA
CIPLDGEHDIPKHDYVCLTMSLPHRLGTTLTTIPAGTPYLSVPPAYAAQWKGRLPEGARRVGLVWAGDPRPDQPAINAVD
RRRSLDARAYLPLLRVPGITFISLQKGALTQPQIDTLPLEFRPFDPMHGVHEFADTAAIIEQLDLVISVDTSIAHLAGAL
NRPTWVLSRYDGCWRWLHDRDDTPWYPRTRLFRQTQPGEWDGVIERVRIALEQWPAHERAPT
>Mature_542_residues
MYGDWQNSQAKVDRYSSAVSQYGNARFDAALALLEPLLTSHTADAHVFNLAAACCLSLDRLDHAEIYWRRAIALKPDYCD
AHNNLGVVLKESGRLDEAKACYHKALSISPTHAGAYVNLGRLHAQLGRSDEAESCYLRALELQPGDGDVYVNLGVLYQEQ
MRLREAEAAYKSAIAANPRDAKAHFNLGVVLKMQHRFAEAEASYRHTLALRPDYFEVKINLAHLLLNVGRLEEGWALFET
RYERAWPARKVAPPPVDFPLWRGEPLAGKSLLVWPEQGHGDSLQFCRYLPMLKALGLAKLSLACSPALRSLLETIEGVDA
CIPLDGEHDIPKHDYVCLTMSLPHRLGTTLTTIPAGTPYLSVPPAYAAQWKGRLPEGARRVGLVWAGDPRPDQPAINAVD
RRRSLDARAYLPLLRVPGITFISLQKGALTQPQIDTLPLEFRPFDPMHGVHEFADTAAIIEQLDLVISVDTSIAHLAGAL
NRPTWVLSRYDGCWRWLHDRDDTPWYPRTRLFRQTQPGEWDGVIERVRIALEQWPAHERAPT

Specific function: Unknown

COG id: COG0457

COG function: function code R; FOG: TPR repeat

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 4 TPR repeats [H]

Homologues:

Organism=Homo sapiens, GI32307150, Length=199, Percent_Identity=35.1758793969849, Blast_Score=106, Evalue=5e-23,
Organism=Homo sapiens, GI32307148, Length=199, Percent_Identity=35.1758793969849, Blast_Score=106, Evalue=6e-23,
Organism=Homo sapiens, GI118766330, Length=172, Percent_Identity=35.4651162790698, Blast_Score=94, Evalue=4e-19,
Organism=Homo sapiens, GI118766328, Length=172, Percent_Identity=35.4651162790698, Blast_Score=94, Evalue=5e-19,
Organism=Homo sapiens, GI301336134, Length=182, Percent_Identity=32.4175824175824, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI83415184, Length=182, Percent_Identity=32.4175824175824, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI224809432, Length=180, Percent_Identity=32.2222222222222, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI22749211, Length=196, Percent_Identity=30.1020408163265, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI167466177, Length=174, Percent_Identity=27.5862068965517, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI167466175, Length=174, Percent_Identity=27.5862068965517, Blast_Score=71, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI115532690, Length=199, Percent_Identity=33.6683417085427, Blast_Score=103, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI115532692, Length=199, Percent_Identity=33.6683417085427, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI25147174, Length=130, Percent_Identity=36.9230769230769, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI17647755, Length=199, Percent_Identity=34.1708542713568, Blast_Score=105, Evalue=7e-23,
Organism=Drosophila melanogaster, GI24585827, Length=199, Percent_Identity=34.1708542713568, Blast_Score=105, Evalue=7e-23,
Organism=Drosophila melanogaster, GI24585829, Length=199, Percent_Identity=34.1708542713568, Blast_Score=105, Evalue=7e-23,
Organism=Drosophila melanogaster, GI24656717, Length=212, Percent_Identity=27.8301886792453, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI18110006, Length=212, Percent_Identity=27.8301886792453, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI161076610, Length=168, Percent_Identity=33.9285714285714, Blast_Score=80, Evalue=5e-15,
Organism=Drosophila melanogaster, GI19920486, Length=168, Percent_Identity=33.9285714285714, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24647123, Length=171, Percent_Identity=28.0701754385965, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI281364285, Length=198, Percent_Identity=29.2929292929293, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24581187, Length=198, Percent_Identity=29.2929292929293, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 60723; Mature: 60723

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: PS50005 TPR L=RR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYGDWQNSQAKVDRYSSAVSQYGNARFDAALALLEPLLTSHTADAHVFNLAAACCLSLDR
CCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHC
LDHAEIYWRRAIALKPDYCDAHNNLGVVLKESGRLDEAKACYHKALSISPTHAGAYVNLG
CCHHHHHHHHHEEECCCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCCCCCEEEHH
RLHAQLGRSDEAESCYLRALELQPGDGDVYVNLGVLYQEQMRLREAEAAYKSAIAANPRD
HHHHHHCCCCCCCCEEEEEEEECCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCC
AKAHFNLGVVLKMQHRFAEAEASYRHTLALRPDYFEVKINLAHLLLNVGRLEEGWALFET
CCEEECEEEEEEEHHHHHHHHCCCCEEEEECCCEEEEEEEHHHHHHHHCCCCCCHHHHHH
RYERAWPARKVAPPPVDFPLWRGEPLAGKSLLVWPEQGHGDSLQFCRYLPMLKALGLAKL
HHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCHHHH
SLACSPALRSLLETIEGVDACIPLDGEHDIPKHDYVCLTMSLPHRLGTTLTTIPAGTPYL
HHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCEEEEEEECCHHHCCEEEECCCCCCCE
SVPPAYAAQWKGRLPEGARRVGLVWAGDPRPDQPAINAVDRRRSLDARAYLPLLRVPGIT
ECCCCHHHHHCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCHHHHCHHHHCCCEE
FISLQKGALTQPQIDTLPLEFRPFDPMHGVHEFADTAAIIEQLDLVISVDTSIAHLAGAL
EEEECCCCCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHC
NRPTWVLSRYDGCWRWLHDRDDTPWYPRTRLFRQTQPGEWDGVIERVRIALEQWPAHERA
CCCEEEEECCCHHHHHHCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCC
PT
CC
>Mature Secondary Structure
MYGDWQNSQAKVDRYSSAVSQYGNARFDAALALLEPLLTSHTADAHVFNLAAACCLSLDR
CCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHC
LDHAEIYWRRAIALKPDYCDAHNNLGVVLKESGRLDEAKACYHKALSISPTHAGAYVNLG
CCHHHHHHHHHEEECCCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCCCCCEEEHH
RLHAQLGRSDEAESCYLRALELQPGDGDVYVNLGVLYQEQMRLREAEAAYKSAIAANPRD
HHHHHHCCCCCCCCEEEEEEEECCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCC
AKAHFNLGVVLKMQHRFAEAEASYRHTLALRPDYFEVKINLAHLLLNVGRLEEGWALFET
CCEEECEEEEEEEHHHHHHHHCCCCEEEEECCCEEEEEEEHHHHHHHHCCCCCCHHHHHH
RYERAWPARKVAPPPVDFPLWRGEPLAGKSLLVWPEQGHGDSLQFCRYLPMLKALGLAKL
HHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCHHHH
SLACSPALRSLLETIEGVDACIPLDGEHDIPKHDYVCLTMSLPHRLGTTLTTIPAGTPYL
HHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCEEEEEEECCHHHCCEEEECCCCCCCE
SVPPAYAAQWKGRLPEGARRVGLVWAGDPRPDQPAINAVDRRRSLDARAYLPLLRVPGIT
ECCCCHHHHHCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCHHHHCHHHHCCCEE
FISLQKGALTQPQIDTLPLEFRPFDPMHGVHEFADTAAIIEQLDLVISVDTSIAHLAGAL
EEEECCCCCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHC
NRPTWVLSRYDGCWRWLHDRDDTPWYPRTRLFRQTQPGEWDGVIERVRIALEQWPAHERA
CCCEEEEECCCHHHHHHCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCC
PT
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9748431; 11259647; 1699845 [H]