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The map label for this gene is nadA

Identifier: 186475347

GI number: 186475347

Start: 658697

End: 659827

Strand: Direct

Name: nadA

Synonym: Bphy_0580

Alternate gene names: 186475347

Gene position: 658697-659827 (Clockwise)

Preceding gene: 186475346

Following gene: 186475348

Centisome position: 18.93

GC content: 60.83

Gene sequence:

>1131_bases
ATGAATCAGGCGATCAGGAGCGTCGAGTACGACCGTCCGCAAGGCACGGCCTGCAGCATCGGCCAGGCTTGGGCGAAAGT
GCCCGATTCACCTTCAACGCACGAACGGCTCGCGTTGAAGGAGCGCATTCGCGGCTTGCTTAAGCGCGAAAAAGCAGTGC
TCGTTGCGCATTACTACGTCGACGCTGAGTTGCAGGAACTGGCCGACGAGACGGGCGGCTGTGTGGCCGATTCGCTTGAA
ATGGCACGCTTCGGGCGGGATCACGACGCCCAGACGCTGGTGGTCGCCGGGGTGCGATTCATGGGTGAGACGGCGAAAAT
TCTTAGTCCGAACAAGCGCATTCTGATGCCTGATCTCGACGCGACCTGTTCGCTTGATCTCGGCTGTCCCGTCGACGAGT
TTTCTGCATTCTGCGACGCTCATCCGGACCGCATCGTCGTCGTCTACGCGAATACGAGCGCGGCTGTGAAGGCGCGCGCC
GACTGGATGGTGACGTCGTCGATCGGGCTCGAAATCGTCGCCGATCTTCATGCGCGCGGTGAAAAGATTATCTGGGCACC
AGACCGTCATCTCGGCGGCTATATCCAGAAAAAGACGGGCGCCGACATGCTGCTGTGGCAAGGCTCGTGTCTTGTCCACG
ACGAATTCAAGGGCGTCGAGCTTGATCTGCTGCGCGCCGAATATCCGGACGCCAAAGTGCTCGTGCATCCGGAGTCGCCG
GAAAGCGTGGTTGCGCAGGCCGATGTGGTCGGTTCGACGACCCAGCTGATCGACGCGGCGAAGAACAGCAGTGCGACGCA
CTTCATTGTCGCGACCGATCTCGGTATCCTGCACAAAATGCGTATCGCGGCTCCCGGCAAGACGTTCATTGAAGCGCCCA
CGGCGGGCAATAGCGCGACGTGCAAGAGTTGCGCGCACTGTCCGTGGATGGCGATGAACGGGCTGCGTAATCTCGCGGAA
GTACTAGAGCGTGGGCACAACGAAATCTTCGTCGATGCGGCAATCGGCGAGCGCGCACGACTGCCGATCGATCGCATGCT
CGATTTCGCAGCGCGTCACAAGAAGCGCGTGCAGGCGAGCGGCGATCTCGCGCACGACACCGCGTTGTTCTCGAACGTTG
GAGCGGCTTGA

Upstream 100 bases:

>100_bases
GTCACAAAACCCCGCGTTGGCGGGGTTTTGCTTTTTGGGCCGTCGGAATCCGGTCGCGGTATCGGCTCTGGGCGGCGGAA
TCAGCAGGGCAGAGGGGATC

Downstream 100 bases:

>100_bases
TGGGCGTGAACGAACCGCTGGAGTTCAAGGACGCCGTGTCGCCGCTTTTCGCGGAAATTCAGGAACAGTACGGCGAAGCG
TTCGCGGCGGCGATCGCGCG

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 376; Mature: 376

Protein sequence:

>376_residues
MNQAIRSVEYDRPQGTACSIGQAWAKVPDSPSTHERLALKERIRGLLKREKAVLVAHYYVDAELQELADETGGCVADSLE
MARFGRDHDAQTLVVAGVRFMGETAKILSPNKRILMPDLDATCSLDLGCPVDEFSAFCDAHPDRIVVVYANTSAAVKARA
DWMVTSSIGLEIVADLHARGEKIIWAPDRHLGGYIQKKTGADMLLWQGSCLVHDEFKGVELDLLRAEYPDAKVLVHPESP
ESVVAQADVVGSTTQLIDAAKNSSATHFIVATDLGILHKMRIAAPGKTFIEAPTAGNSATCKSCAHCPWMAMNGLRNLAE
VLERGHNEIFVDAAIGERARLPIDRMLDFAARHKKRVQASGDLAHDTALFSNVGAA

Sequences:

>Translated_376_residues
MNQAIRSVEYDRPQGTACSIGQAWAKVPDSPSTHERLALKERIRGLLKREKAVLVAHYYVDAELQELADETGGCVADSLE
MARFGRDHDAQTLVVAGVRFMGETAKILSPNKRILMPDLDATCSLDLGCPVDEFSAFCDAHPDRIVVVYANTSAAVKARA
DWMVTSSIGLEIVADLHARGEKIIWAPDRHLGGYIQKKTGADMLLWQGSCLVHDEFKGVELDLLRAEYPDAKVLVHPESP
ESVVAQADVVGSTTQLIDAAKNSSATHFIVATDLGILHKMRIAAPGKTFIEAPTAGNSATCKSCAHCPWMAMNGLRNLAE
VLERGHNEIFVDAAIGERARLPIDRMLDFAARHKKRVQASGDLAHDTALFSNVGAA
>Mature_376_residues
MNQAIRSVEYDRPQGTACSIGQAWAKVPDSPSTHERLALKERIRGLLKREKAVLVAHYYVDAELQELADETGGCVADSLE
MARFGRDHDAQTLVVAGVRFMGETAKILSPNKRILMPDLDATCSLDLGCPVDEFSAFCDAHPDRIVVVYANTSAAVKARA
DWMVTSSIGLEIVADLHARGEKIIWAPDRHLGGYIQKKTGADMLLWQGSCLVHDEFKGVELDLLRAEYPDAKVLVHPESP
ESVVAQADVVGSTTQLIDAAKNSSATHFIVATDLGILHKMRIAAPGKTFIEAPTAGNSATCKSCAHCPWMAMNGLRNLAE
VLERGHNEIFVDAAIGERARLPIDRMLDFAARHKKRVQASGDLAHDTALFSNVGAA

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1786964, Length=326, Percent_Identity=65.3374233128834, Blast_Score=447, Evalue=1e-127,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NADA_BURP8 (B2JDZ5)

Other databases:

- EMBL:   CP001043
- RefSeq:   YP_001856817.1
- GeneID:   6242080
- GenomeReviews:   CP001043_GR
- KEGG:   bph:Bphy_0580
- HOGENOM:   HBG291157
- OMA:   IAHPECE
- ProtClustDB:   PRK09375
- GO:   GO:0005737
- HAMAP:   MF_00567
- InterPro:   IPR003473
- TIGRFAMs:   TIGR00550

Pfam domain/function: PF02445 NadA

EC number: =2.5.1.72

Molecular weight: Translated: 40830; Mature: 40830

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: NA

Important sites: BINDING 57-57 BINDING 78-78 BINDING 149-149 BINDING 166-166 BINDING 236-236 BINDING 253-253

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQAIRSVEYDRPQGTACSIGQAWAKVPDSPSTHERLALKERIRGLLKREKAVLVAHYYV
CCHHHHCCCCCCCCCCEECCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEEEE
DAELQELADETGGCVADSLEMARFGRDHDAQTLVVAGVRFMGETAKILSPNKRILMPDLD
CHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCEEEEHHHHHHCCCHHHCCCCCEEEECCCC
ATCSLDLGCPVDEFSAFCDAHPDRIVVVYANTSAAVKARADWMVTSSIGLEIVADLHARG
CCEEEECCCCHHHHHHHHCCCCCEEEEEEECCCCEEEECCCEEEECCCCCEEEEHHHCCC
EKIIWAPDRHLGGYIQKKTGADMLLWQGSCLVHDEFKGVELDLLRAEYPDAKVLVHPESP
CEEEECCCCCCCCEEECCCCCCEEEECCCEEEECCCCCCEEEEEECCCCCCEEEECCCCC
ESVVAQADVVGSTTQLIDAAKNSSATHFIVATDLGILHKMRIAAPGKTFIEAPTAGNSAT
HHHHHHHHHCCCHHHHHHHHCCCCCEEEEEEECHHHHHHHEECCCCCCEEECCCCCCCCC
CKSCAHCPWMAMNGLRNLAEVLERGHNEIFVDAAIGERARLPIDRMLDFAARHKKRVQAS
HHHHCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCC
GDLAHDTALFSNVGAA
CCCHHHHHHHHHCCCC
>Mature Secondary Structure
MNQAIRSVEYDRPQGTACSIGQAWAKVPDSPSTHERLALKERIRGLLKREKAVLVAHYYV
CCHHHHCCCCCCCCCCEECCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEEEE
DAELQELADETGGCVADSLEMARFGRDHDAQTLVVAGVRFMGETAKILSPNKRILMPDLD
CHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCEEEEHHHHHHCCCHHHCCCCCEEEECCCC
ATCSLDLGCPVDEFSAFCDAHPDRIVVVYANTSAAVKARADWMVTSSIGLEIVADLHARG
CCEEEECCCCHHHHHHHHCCCCCEEEEEEECCCCEEEECCCEEEECCCCCEEEEHHHCCC
EKIIWAPDRHLGGYIQKKTGADMLLWQGSCLVHDEFKGVELDLLRAEYPDAKVLVHPESP
CEEEECCCCCCCCEEECCCCCCEEEECCCEEEECCCCCCEEEEEECCCCCCEEEECCCCC
ESVVAQADVVGSTTQLIDAAKNSSATHFIVATDLGILHKMRIAAPGKTFIEAPTAGNSAT
HHHHHHHHHCCCHHHHHHHHCCCCCEEEEEEECHHHHHHHEECCCCCCEEECCCCCCCCC
CKSCAHCPWMAMNGLRNLAEVLERGHNEIFVDAAIGERARLPIDRMLDFAARHKKRVQAS
HHHHCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCC
GDLAHDTALFSNVGAA
CCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA