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The map label for this gene is yieP [H]

Identifier: 186475203

GI number: 186475203

Start: 493390

End: 494253

Strand: Direct

Name: yieP [H]

Synonym: Bphy_0434

Alternate gene names: 186475203

Gene position: 493390-494253 (Clockwise)

Preceding gene: 186475200

Following gene: 186475204

Centisome position: 14.18

GC content: 62.38

Gene sequence:

>864_bases
GTGCGACCGTCGAGGAACGACATCCTACATCAAAATCGCCGTAAAATACTATTAATAGTATTATTCGGTGCATGGATTTC
GCGGCGACGGTGGGTTTCGCGCCCGCAATCGCCGATAATCGCGGGCGATCCACGTCGCCGTTCGGGCGGCATCGGGCAAA
TATCAAACAGCTTCGGGAGAACCGACATCCAGCGAGATCTGCACGGCCGCGTCGCGTGGCTGCTTGGCACAGCCATCCTG
CGCGGCGACTACGCGCCCGAATCCGTCTTGCCGCGCGAAGCCGAGTTGATGGAGACATTCGGGGTAAGCCGCACGGTGTT
GCGTGAAGCGTTGCGCACCTTGACGTCGAAGGGGTTGATCGAATCGCGGCCGCGCGTTGGCACGCGCGTGCGTCCAAAGC
ACGCATGGAATCTGCTGGATGCCGATATGCTCGACTGGTATTCGCGTGTGGCGCCCGCACTGGATTTCGCGCTAAAACTG
CAGGAAATGCGCGAGATGATCGAGCCTTATGCGGCCGCGCTCGCCGCTGCATCGCATAGCGACGCCACGTTCGGCGCGCT
CGATGCCGCGCATTCGGCGATGGTCGCGGCGCGCAATGTCGATGAATGGGTGCGCGCCGACCTGCAATTTCATCTGAGCG
TGCTGGCCGCGTGCAGCAACGAATTGCTGGTGCCGCTCGGCACGCTGATTGAGCGCACGCTCGAGGCGCAATTGCGTCTG
AATGCGAAGCGAGCCGAGGTGTTCAATGCGTCGCTGGCCGAGCATACGGCAGTTTTCGAGGCCATCCGCGATCGCGATGC
GCCGCGCGCGCGTCACGCAATGGCATCGCTGCTCGGCGTCACGCGCGGACGGATCGAAGGCTGA

Upstream 100 bases:

>100_bases
TTTTGGTGATCTTCATTGGGGTGTCTCCTTGGCTTGCAGATGCTAATTGCGGTTGTTGGCCCGCACCGTGGCCGCGCGTC
CCACTGTGTGGACGCCGCTT

Downstream 100 bases:

>100_bases
TTGACGGCGGGATCAATCCATCGGCGCGTGCGTGACCGATTCGTCGGGCGCCTTGCGCGACGGGCGGATCAGCAACACGA
GAGGAATCACGAGCAGCGTC

Product: GntR domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 287; Mature: 287

Protein sequence:

>287_residues
MRPSRNDILHQNRRKILLIVLFGAWISRRRWVSRPQSPIIAGDPRRRSGGIGQISNSFGRTDIQRDLHGRVAWLLGTAIL
RGDYAPESVLPREAELMETFGVSRTVLREALRTLTSKGLIESRPRVGTRVRPKHAWNLLDADMLDWYSRVAPALDFALKL
QEMREMIEPYAAALAAASHSDATFGALDAAHSAMVAARNVDEWVRADLQFHLSVLAACSNELLVPLGTLIERTLEAQLRL
NAKRAEVFNASLAEHTAVFEAIRDRDAPRARHAMASLLGVTRGRIEG

Sequences:

>Translated_287_residues
MRPSRNDILHQNRRKILLIVLFGAWISRRRWVSRPQSPIIAGDPRRRSGGIGQISNSFGRTDIQRDLHGRVAWLLGTAIL
RGDYAPESVLPREAELMETFGVSRTVLREALRTLTSKGLIESRPRVGTRVRPKHAWNLLDADMLDWYSRVAPALDFALKL
QEMREMIEPYAAALAAASHSDATFGALDAAHSAMVAARNVDEWVRADLQFHLSVLAACSNELLVPLGTLIERTLEAQLRL
NAKRAEVFNASLAEHTAVFEAIRDRDAPRARHAMASLLGVTRGRIEG
>Mature_287_residues
MRPSRNDILHQNRRKILLIVLFGAWISRRRWVSRPQSPIIAGDPRRRSGGIGQISNSFGRTDIQRDLHGRVAWLLGTAIL
RGDYAPESVLPREAELMETFGVSRTVLREALRTLTSKGLIESRPRVGTRVRPKHAWNLLDADMLDWYSRVAPALDFALKL
QEMREMIEPYAAALAAASHSDATFGALDAAHSAMVAARNVDEWVRADLQFHLSVLAACSNELLVPLGTLIERTLEAQLRL
NAKRAEVFNASLAEHTAVFEAIRDRDAPRARHAMASLLGVTRGRIEG

Specific function: Repressor For The Dgorkat Operon. Binds D-Galactonate As An Inducer. [C]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI48994961, Length=218, Percent_Identity=32.5688073394495, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI48994955, Length=221, Percent_Identity=33.0316742081448, Blast_Score=107, Evalue=1e-24,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 32034; Mature: 32034

Theoretical pI: Translated: 11.03; Mature: 11.03

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPSRNDILHQNRRKILLIVLFGAWISRRRWVSRPQSPIIAGDPRRRSGGIGQISNSFGR
CCCCHHHHHHCCCHHEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHCCH
TDIQRDLHGRVAWLLGTAILRGDYAPESVLPREAELMETFGVSRTVLREALRTLTSKGLI
HHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCHH
ESRPRVGTRVRPKHAWNLLDADMLDWYSRVAPALDFALKLQEMREMIEPYAAALAAASHS
HCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DATFGALDAAHSAMVAARNVDEWVRADLQFHLSVLAACSNELLVPLGTLIERTLEAQLRL
CCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
NAKRAEVFNASLAEHTAVFEAIRDRDAPRARHAMASLLGVTRGRIEG
CHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRPSRNDILHQNRRKILLIVLFGAWISRRRWVSRPQSPIIAGDPRRRSGGIGQISNSFGR
CCCCHHHHHHCCCHHEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHCCH
TDIQRDLHGRVAWLLGTAILRGDYAPESVLPREAELMETFGVSRTVLREALRTLTSKGLI
HHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCHH
ESRPRVGTRVRPKHAWNLLDADMLDWYSRVAPALDFALKLQEMREMIEPYAAALAAASHS
HCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DATFGALDAAHSAMVAARNVDEWVRADLQFHLSVLAACSNELLVPLGTLIERTLEAQLRL
CCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
NAKRAEVFNASLAEHTAVFEAIRDRDAPRARHAMASLLGVTRGRIEG
CHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503 [H]