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The map label for this gene is ycgM [C]

Identifier: 186475075

GI number: 186475075

Start: 349409

End: 350107

Strand: Direct

Name: ycgM [C]

Synonym: Bphy_0306

Alternate gene names: 186475075

Gene position: 349409-350107 (Clockwise)

Preceding gene: 186475072

Following gene: 186475076

Centisome position: 10.04

GC content: 60.94

Gene sequence:

>699_bases
ATGGGTTACGTGTTTGCGCCAGCGCCGGTGACGGCTGTGCCAGTCGTCGGATCGGACGATCAATTCGCGGTACGCCGCAT
TTACTGCGTCGGCCGCAATTACGAAGCGCATGCGCGCGAAATGGGCCATGATCCCGACCGCGAACCGCCGTTCTTCTTCG
CGAAGCCCGCCGACGCCGTGCTCTACGTCGCGCCCGGTGCCACGGGTGAATTTCCGTATCCGGCGCAGTCAAAGAATGTC
CACTACGAAATGGAACTCGTCGCGGCAATCGGCAAGGCGGGCAAGAACATTCCCGCCAGCAACGCGCTCGATCACGTCTA
TGGCTACGCGCTCGGTCTCGATATGACGCGCCGCGATTTGCAGGCGGAAGCGAAGAAACTGGGGCGTCCGTGGGACACCG
CGAAGGGCTTCGACTACTCGGCGCCGCTCGGTCCGATTCATCCCGTTTCCAAGGTCGGTCACGTCGACAAAGGCGCGATC
TTTCTTACCGTCAACGGGGAAGAAAAGCAGCGCTCGGATGTGTCTCAGTTGATCTGGTCTGTGGCTGAGACAATCGAGTA
TCTGTCCAGCTTCTTCGAATTGCAGCCCGGCGATCTGATTTTCACGGGTACGCCCGAAGGCGTCGGCGCCATCGTCCGTG
GCGACCTGATGAAGGGCGGCGTTGAGGGGCTGGGCGAATTCAGCGTGCGCATGGTGTAA

Upstream 100 bases:

>100_bases
TTGCCACCTGGCCGTTCGGCCACGCGGCACGCGAAACGGCGCCGCGTTACACTCAATATTTCGCCGTGTCAGAGCGGCTC
AATAGAAGACGGAGAACGGA

Downstream 100 bases:

>100_bases
CGTCCGCCGATTCAATCAGGGGGGAGACTACACAATGAAGCTATACAGCTACTTTCGCAGCTCGGCGTCCTATCGCGTGC
GCATCGCGCTGAATCTGAAG

Product: fumarylacetoacetate (FAA) hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 232; Mature: 231

Protein sequence:

>232_residues
MGYVFAPAPVTAVPVVGSDDQFAVRRIYCVGRNYEAHAREMGHDPDREPPFFFAKPADAVLYVAPGATGEFPYPAQSKNV
HYEMELVAAIGKAGKNIPASNALDHVYGYALGLDMTRRDLQAEAKKLGRPWDTAKGFDYSAPLGPIHPVSKVGHVDKGAI
FLTVNGEEKQRSDVSQLIWSVAETIEYLSSFFELQPGDLIFTGTPEGVGAIVRGDLMKGGVEGLGEFSVRMV

Sequences:

>Translated_232_residues
MGYVFAPAPVTAVPVVGSDDQFAVRRIYCVGRNYEAHAREMGHDPDREPPFFFAKPADAVLYVAPGATGEFPYPAQSKNV
HYEMELVAAIGKAGKNIPASNALDHVYGYALGLDMTRRDLQAEAKKLGRPWDTAKGFDYSAPLGPIHPVSKVGHVDKGAI
FLTVNGEEKQRSDVSQLIWSVAETIEYLSSFFELQPGDLIFTGTPEGVGAIVRGDLMKGGVEGLGEFSVRMV
>Mature_231_residues
GYVFAPAPVTAVPVVGSDDQFAVRRIYCVGRNYEAHAREMGHDPDREPPFFFAKPADAVLYVAPGATGEFPYPAQSKNVH
YEMELVAAIGKAGKNIPASNALDHVYGYALGLDMTRRDLQAEAKKLGRPWDTAKGFDYSAPLGPIHPVSKVGHVDKGAIF
LTVNGEEKQRSDVSQLIWSVAETIEYLSSFFELQPGDLIFTGTPEGVGAIVRGDLMKGGVEGLGEFSVRMV

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI215422413, Length=204, Percent_Identity=41.6666666666667, Blast_Score=157, Evalue=5e-39,
Organism=Homo sapiens, GI66348062, Length=200, Percent_Identity=42, Blast_Score=157, Evalue=9e-39,
Organism=Homo sapiens, GI13654274, Length=207, Percent_Identity=40.5797101449275, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI156231349, Length=208, Percent_Identity=34.6153846153846, Blast_Score=119, Evalue=2e-27,
Organism=Homo sapiens, GI40786394, Length=215, Percent_Identity=33.953488372093, Blast_Score=119, Evalue=3e-27,
Organism=Escherichia coli, GI1787428, Length=203, Percent_Identity=34.9753694581281, Blast_Score=133, Evalue=9e-33,
Organism=Caenorhabditis elegans, GI17557057, Length=197, Percent_Identity=39.0862944162437, Blast_Score=147, Evalue=3e-36,
Organism=Saccharomyces cerevisiae, GI6324161, Length=221, Percent_Identity=31.6742081447964, Blast_Score=121, Evalue=1e-28,
Organism=Drosophila melanogaster, GI28571789, Length=209, Percent_Identity=34.4497607655502, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI28572127, Length=216, Percent_Identity=34.7222222222222, Blast_Score=117, Evalue=5e-27,
Organism=Drosophila melanogaster, GI24663695, Length=218, Percent_Identity=28.8990825688073, Blast_Score=84, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 25134; Mature: 25003

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGYVFAPAPVTAVPVVGSDDQFAVRRIYCVGRNYEAHAREMGHDPDREPPFFFAKPADAV
CCEEECCCCCEEEEEECCCCCEEEEEEEEECCCCHHHHHHCCCCCCCCCCEEEECCCCEE
LYVAPGATGEFPYPAQSKNVHYEMELVAAIGKAGKNIPASNALDHVYGYALGLDMTRRDL
EEEECCCCCCCCCCCCCCCEEEHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCHHHHHH
QAEAKKLGRPWDTAKGFDYSAPLGPIHPVSKVGHVDKGAIFLTVNGEEKQRSDVSQLIWS
HHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHH
VAETIEYLSSFFELQPGDLIFTGTPEGVGAIVRGDLMKGGVEGLGEFSVRMV
HHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHEHHHHHCCHHCCCCEEEEEC
>Mature Secondary Structure 
GYVFAPAPVTAVPVVGSDDQFAVRRIYCVGRNYEAHAREMGHDPDREPPFFFAKPADAV
CEEECCCCCEEEEEECCCCCEEEEEEEEECCCCHHHHHHCCCCCCCCCCEEEECCCCEE
LYVAPGATGEFPYPAQSKNVHYEMELVAAIGKAGKNIPASNALDHVYGYALGLDMTRRDL
EEEECCCCCCCCCCCCCCCEEEHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCHHHHHH
QAEAKKLGRPWDTAKGFDYSAPLGPIHPVSKVGHVDKGAIFLTVNGEEKQRSDVSQLIWS
HHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHH
VAETIEYLSSFFELQPGDLIFTGTPEGVGAIVRGDLMKGGVEGLGEFSVRMV
HHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHEHHHHHCCHHCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]