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The map label for this gene is queD [H]

Identifier: 186474816

GI number: 186474816

Start: 52693

End: 53139

Strand: Direct

Name: queD [H]

Synonym: Bphy_0045

Alternate gene names: 186474816

Gene position: 52693-53139 (Clockwise)

Preceding gene: 186474815

Following gene: 186474817

Centisome position: 1.51

GC content: 59.51

Gene sequence:

>447_bases
GTGCTGACGATTACCCGAAAACTCGAATTCGACGCGGGCCACCGCATTCCCGATCACCGCAGCCAGTGCCGGAATCTGCA
CGGTCACCGCTACGTGCTCGAAATCACGCTGCAAGGCGATCTGGTCGAAACGGAAGGCGCGCCGGATCGCGGCATGGTGA
TGGATTTCGCCGACGTGAAAGCGCTCGCGAACGAACATCTCGTTGACAAGTGGGACCACGCGTTTCTCGTCTACGAAGGC
GATACGCAAGTGCGCGGCTTTCTCGAAACGATGGCCGGCCACAAGACGGTCGTGCTCGATCGCATTCCAACTGTCGAAAA
TCTCGCCGCTGTCGCGTTCGACATTCTCGCGAACGTCTACGACGCGCACTATGGCGTGAACCTGAGGCTGCATAAGCTGC
GTCTGTACGAGACGCCGAATTGCTGGGCCGACGTCGTGCGCGACTAA

Upstream 100 bases:

>100_bases
GGACATCAACACGAAGCTCGCGATCGACTGGTGCAAGCGCCATCCGCAATGGCGCCTGTCGATGCAGACTCACAAGTACC
TGAACATTCCCTGATTTGCC

Downstream 100 bases:

>100_bases
ACGGGTTATTGTCACGGTATGATCGTTTCGATAACCACACGGAGCGAGACATGCCGGTCACCGCGCTACGCAGCGGGCTC
GACGCCCGCCACGACTTTCA

Product: queuosine biosynthesis protein QueD

Products: NA

Alternate protein names: CPH4 synthase; Queuosine biosynthesis protein queD [H]

Number of amino acids: Translated: 148; Mature: 148

Protein sequence:

>148_residues
MLTITRKLEFDAGHRIPDHRSQCRNLHGHRYVLEITLQGDLVETEGAPDRGMVMDFADVKALANEHLVDKWDHAFLVYEG
DTQVRGFLETMAGHKTVVLDRIPTVENLAAVAFDILANVYDAHYGVNLRLHKLRLYETPNCWADVVRD

Sequences:

>Translated_148_residues
MLTITRKLEFDAGHRIPDHRSQCRNLHGHRYVLEITLQGDLVETEGAPDRGMVMDFADVKALANEHLVDKWDHAFLVYEG
DTQVRGFLETMAGHKTVVLDRIPTVENLAAVAFDILANVYDAHYGVNLRLHKLRLYETPNCWADVVRD
>Mature_148_residues
MLTITRKLEFDAGHRIPDHRSQCRNLHGHRYVLEITLQGDLVETEGAPDRGMVMDFADVKALANEHLVDKWDHAFLVYEG
DTQVRGFLETMAGHKTVVLDRIPTVENLAAVAFDILANVYDAHYGVNLRLHKLRLYETPNCWADVVRD

Specific function: Catalyzes the conversion of 7,8-dihydroneopterin triphosphate (H2NTP) to 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) and acetaldehyde [H]

COG id: COG0720

COG function: function code H; 6-pyruvoyl-tetrahydropterin synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTPS family. QueD subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007115 [H]

Pfam domain/function: PF01242 PTPS [H]

EC number: NA

Molecular weight: Translated: 16908; Mature: 16908

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTITRKLEFDAGHRIPDHRSQCRNLHGHRYVLEITLQGDLVETEGAPDRGMVMDFADVK
CEEEEEEEECCCCCCCCCHHHHHHCCCCCEEEEEEEECCCEEECCCCCCCCEEEEHHHHH
ALANEHLVDKWDHAFLVYEGDTQVRGFLETMAGHKTVVLDRIPTVENLAAVAFDILANVY
HHHHHHCCCCCCCEEEEEECCHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHH
DAHYGVNLRLHKLRLYETPNCWADVVRD
HHCCCCEEEEEEEEEEECCCHHHHHHCC
>Mature Secondary Structure
MLTITRKLEFDAGHRIPDHRSQCRNLHGHRYVLEITLQGDLVETEGAPDRGMVMDFADVK
CEEEEEEEECCCCCCCCCHHHHHHCCCCCEEEEEEEECCCEEECCCCCCCCEEEEHHHHH
ALANEHLVDKWDHAFLVYEGDTQVRGFLETMAGHKTVVLDRIPTVENLAAVAFDILANVY
HHHHHHCCCCCCCEEEEEECCHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHH
DAHYGVNLRLHKLRLYETPNCWADVVRD
HHCCCCEEEEEEEEEEECCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA