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The map label for this gene is queC [H]

Identifier: 186474814

GI number: 186474814

Start: 51253

End: 51984

Strand: Direct

Name: queC [H]

Synonym: Bphy_0043

Alternate gene names: 186474814

Gene position: 51253-51984 (Clockwise)

Preceding gene: 186474813

Following gene: 186474815

Centisome position: 1.47

GC content: 63.8

Gene sequence:

>732_bases
GTGACCCGCAAAGACGCGAAGAGTAGCGCCCTGGTGCTGTTTTCCGGCGGCCAGGATTCGGCCACATGTCTCGCTTGGGC
GCTGGATCGATATGAGACGGTCGAAACCCTGGGTTTCGACTACGGCCAGCGGCATCGCGTCGAACTCGAGTGCCGCGAAG
GCTTTCGCAGCGCAGTGGCGCGCACCTTCCCGGAGTGGGGCGAGCGGCTCGGCGACGATCACATGATCGATCTCTCCGTG
CTCGGCTCGATCAGCGAAACCGCAATGACGCGCGAAATCGAGATTCACGCGGCGTCGAACGGTCTGCCGAACACGTTCGT
GCCCGGCCGCAATCTGATGTTCATGACGATTGCGGCGGCGATTGCGTATCGGCGCGGGCTGCGGGTGCTGGTCGGCGGCA
TGTGCGAGACGGATTTTTCCGGCTACCCGGATTGCCGCGACGACACGATGAAGGCGCTGCAAGTCGCGCTGAATCTCGGC
ATGGACAGCCGCTTTGTGCTGGAAACGCCGCTGATGTGGATCGACAAGGCCGACACCTGGCGCCTCGCGCATGAGTTGGG
CGGCGACGAACTGGTCGAGTTGATTCGCGTCGAGACGCACACGTGCTATCTCGGCGAGCGCGCGGAACTGCATGCGTGGG
GCTTTGGTTGCGGCGAGTGTCCTGCATGCCGCTTGCGCAAGCGTGGTTATGAGGCGTATCTGAGCGGCGAGCAGGTCACG
GAGCCGGCCTGA

Upstream 100 bases:

>100_bases
CCAGCGTCGGCGCCATGCCCATGCCGCAACGTTCGGCATGGCCTGGAAGCCGCGGCGACGGGCGGCTGGCGCACGCAATC
AACCTACACGGAGTTTCACG

Downstream 100 bases:

>100_bases
AGCTTCACCACGCAAGGCGAAGAGCACACACATCAACAGCGCTTCACGGAGCATCGGGCAGAAAGCAGCATGACGTACGC
GGTCAAGGAAATCTTCTATA

Product: exsB protein

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; PreQ(0) synthase; Queuosine biosynthesis protein queC [H]

Number of amino acids: Translated: 243; Mature: 242

Protein sequence:

>243_residues
MTRKDAKSSALVLFSGGQDSATCLAWALDRYETVETLGFDYGQRHRVELECREGFRSAVARTFPEWGERLGDDHMIDLSV
LGSISETAMTREIEIHAASNGLPNTFVPGRNLMFMTIAAAIAYRRGLRVLVGGMCETDFSGYPDCRDDTMKALQVALNLG
MDSRFVLETPLMWIDKADTWRLAHELGGDELVELIRVETHTCYLGERAELHAWGFGCGECPACRLRKRGYEAYLSGEQVT
EPA

Sequences:

>Translated_243_residues
MTRKDAKSSALVLFSGGQDSATCLAWALDRYETVETLGFDYGQRHRVELECREGFRSAVARTFPEWGERLGDDHMIDLSV
LGSISETAMTREIEIHAASNGLPNTFVPGRNLMFMTIAAAIAYRRGLRVLVGGMCETDFSGYPDCRDDTMKALQVALNLG
MDSRFVLETPLMWIDKADTWRLAHELGGDELVELIRVETHTCYLGERAELHAWGFGCGECPACRLRKRGYEAYLSGEQVT
EPA
>Mature_242_residues
TRKDAKSSALVLFSGGQDSATCLAWALDRYETVETLGFDYGQRHRVELECREGFRSAVARTFPEWGERLGDDHMIDLSVL
GSISETAMTREIEIHAASNGLPNTFVPGRNLMFMTIAAAIAYRRGLRVLVGGMCETDFSGYPDCRDDTMKALQVALNLGM
DSRFVLETPLMWIDKADTWRLAHELGGDELVELIRVETHTCYLGERAELHAWGFGCGECPACRLRKRGYEAYLSGEQVTE
PA

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) [H]

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family [H]

Homologues:

Organism=Escherichia coli, GI1786648, Length=234, Percent_Identity=45.7264957264957, Blast_Score=199, Evalue=1e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018317
- InterPro:   IPR014729 [H]

Pfam domain/function: PF06508 ExsB [H]

EC number: NA

Molecular weight: Translated: 27127; Mature: 26996

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRKDAKSSALVLFSGGQDSATCLAWALDRYETVETLGFDYGQRHRVELECREGFRSAVA
CCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHHHHHHHH
RTFPEWGERLGDDHMIDLSVLGSISETAMTREIEIHAASNGLPNTFVPGRNLMFMTIAAA
HHCHHHHHHCCCCCEEEHHHHCCHHHHHHEEEEEEEECCCCCCCCCCCCCCHHHHHHHHH
IAYRRGLRVLVGGMCETDFSGYPDCRDDTMKALQVALNLGMDSRFVLETPLMWIDKADTW
HHHHCCHHEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCEECCCCHH
RLAHELGGDELVELIRVETHTCYLGERAELHAWGFGCGECPACRLRKRGYEAYLSGEQVT
HHHHHCCHHHHHHHHHHHHHEEECCCCCEEEEECCCCCCCCHHHHHHCCCCEEECCCCCC
EPA
CCC
>Mature Secondary Structure 
TRKDAKSSALVLFSGGQDSATCLAWALDRYETVETLGFDYGQRHRVELECREGFRSAVA
CCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHHHHHHHH
RTFPEWGERLGDDHMIDLSVLGSISETAMTREIEIHAASNGLPNTFVPGRNLMFMTIAAA
HHCHHHHHHCCCCCEEEHHHHCCHHHHHHEEEEEEEECCCCCCCCCCCCCCHHHHHHHHH
IAYRRGLRVLVGGMCETDFSGYPDCRDDTMKALQVALNLGMDSRFVLETPLMWIDKADTW
HHHHCCHHEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCEECCCCHH
RLAHELGGDELVELIRVETHTCYLGERAELHAWGFGCGECPACRLRKRGYEAYLSGEQVT
HHHHHCCHHHHHHHHHHHHHEEECCCCCEEEEECCCCCCCCHHHHHHCCCCEEECCCCCC
EPA
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA