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The map label for this gene is yabD [H]

Identifier: 183222807

GI number: 183222807

Start: 3587477

End: 3588295

Strand: Reverse

Name: yabD [H]

Synonym: LEPBI_I3468

Alternate gene names: 183222807

Gene position: 3588295-3587477 (Counterclockwise)

Preceding gene: 183222812

Following gene: 183222806

Centisome position: 99.68

GC content: 37.36

Gene sequence:

>819_bases
TTGCTATTTATGGGATATTCGACAATAGACACACATTGCCACTTAGACATAATTCGAGAACAAGGACAAAGCATTGAAGA
AACCCTGGAGAAATCCCGAAAAGTTGGAGTAGACCGACTGGTTCAAATTGGCATTGATTTACCAAGTTCGAACGAAGCTG
TTCGTATATCAGAAACATATTCTACAAATGAATTACAAATATCCTATTCGATTGGTTGCCACCCAACAGAAACACATGAA
TTTCCAAACGCAGACCAAATCTTAGAGTTAGCCAAATCCCGAATGTATGATCCGAAATTTTCAGCAATTGGCGAAATTGG
TGTCGATTTGTATCATGATGCGAGCACTCGTTCCCAACAAAACGATGTTCTGCGAAAGTTTTTACAGTTTTCATCTGAAT
ATAAACTTCCAGTTGTGATCCACTCACGTGATGCCTTCGCGGATACTTATGAAGCTCTCAAAGAATATAAAACCAAAGCT
TTTGGTGTGATCCATTGTTTTACTTATGATTATGAAGCTGCAAAACAATTTGTGGACCTTGGGTATTACATTTCTTTTTC
AGGAATTGTGACGTTTAAATCAGCGACCGATATTCAGGAAGCAGCCAAAAAAATTCCACTCGAATCAATGTTGATTGAAA
CTGATGCACCATTTTTATCTCCTATGCCACATAGAGGAAAAAGGAATGATTCCTCTCATTTACCTTTTGTTTTAGAAAAA
ATGTTTAACCTACGCACAGAACCCAATGCGGAAGTAGCAGATCGTATTTATCAGAATTCAATAAAATTTACAGAAAGAAA
GGCCTATCACCATGCTTGA

Upstream 100 bases:

>100_bases
CCACGTTCGTTATAGACCTATGATGATTTAAACAAAAGTTAATCTACCCACTATATCTTTCGATTGAATTTTCATTTTCA
TCCAGTGGAAATTACAAATC

Downstream 100 bases:

>100_bases
TATCAATCGAATTGTTCAGAATCCAGAAGAGTTACTTTCCACCTTACAAAAACGTGGTGTAGTTTCTTCTGACATAGAAG
CAAAGATCAAATCTGTTTCC

Product: putative hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 272; Mature: 272

Protein sequence:

>272_residues
MLFMGYSTIDTHCHLDIIREQGQSIEETLEKSRKVGVDRLVQIGIDLPSSNEAVRISETYSTNELQISYSIGCHPTETHE
FPNADQILELAKSRMYDPKFSAIGEIGVDLYHDASTRSQQNDVLRKFLQFSSEYKLPVVIHSRDAFADTYEALKEYKTKA
FGVIHCFTYDYEAAKQFVDLGYYISFSGIVTFKSATDIQEAAKKIPLESMLIETDAPFLSPMPHRGKRNDSSHLPFVLEK
MFNLRTEPNAEVADRIYQNSIKFTERKAYHHA

Sequences:

>Translated_272_residues
MLFMGYSTIDTHCHLDIIREQGQSIEETLEKSRKVGVDRLVQIGIDLPSSNEAVRISETYSTNELQISYSIGCHPTETHE
FPNADQILELAKSRMYDPKFSAIGEIGVDLYHDASTRSQQNDVLRKFLQFSSEYKLPVVIHSRDAFADTYEALKEYKTKA
FGVIHCFTYDYEAAKQFVDLGYYISFSGIVTFKSATDIQEAAKKIPLESMLIETDAPFLSPMPHRGKRNDSSHLPFVLEK
MFNLRTEPNAEVADRIYQNSIKFTERKAYHHA
>Mature_272_residues
MLFMGYSTIDTHCHLDIIREQGQSIEETLEKSRKVGVDRLVQIGIDLPSSNEAVRISETYSTNELQISYSIGCHPTETHE
FPNADQILELAKSRMYDPKFSAIGEIGVDLYHDASTRSQQNDVLRKFLQFSSEYKLPVVIHSRDAFADTYEALKEYKTKA
FGVIHCFTYDYEAAKQFVDLGYYISFSGIVTFKSATDIQEAAKKIPLESMLIETDAPFLSPMPHRGKRNDSSHLPFVLEK
MFNLRTEPNAEVADRIYQNSIKFTERKAYHHA

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI14042943, Length=275, Percent_Identity=28.7272727272727, Blast_Score=106, Evalue=2e-23,
Organism=Homo sapiens, GI225903439, Length=249, Percent_Identity=30.9236947791165, Blast_Score=99, Evalue=3e-21,
Organism=Homo sapiens, GI225903424, Length=223, Percent_Identity=30.4932735426009, Blast_Score=88, Evalue=9e-18,
Organism=Homo sapiens, GI110349730, Length=278, Percent_Identity=26.6187050359712, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI110349734, Length=278, Percent_Identity=26.978417266187, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI226061614, Length=267, Percent_Identity=26.5917602996255, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI226061853, Length=283, Percent_Identity=26.1484098939929, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI226061595, Length=241, Percent_Identity=27.3858921161826, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1787342, Length=248, Percent_Identity=34.6774193548387, Blast_Score=156, Evalue=1e-39,
Organism=Escherichia coli, GI87082439, Length=254, Percent_Identity=29.9212598425197, Blast_Score=124, Evalue=5e-30,
Organism=Escherichia coli, GI48994985, Length=228, Percent_Identity=32.0175438596491, Blast_Score=108, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17559024, Length=204, Percent_Identity=26.9607843137255, Blast_Score=91, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17543026, Length=225, Percent_Identity=28.8888888888889, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24586117, Length=268, Percent_Identity=26.1194029850746, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI221330018, Length=269, Percent_Identity=26.0223048327138, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24648690, Length=277, Percent_Identity=27.0758122743682, Blast_Score=82, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 31126; Mature: 31126

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFMGYSTIDTHCHLDIIREQGQSIEETLEKSRKVGVDRLVQIGIDLPSSNEAVRISETY
CEEECCCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHCCCCCCCCCEEEEEECC
STNELQISYSIGCHPTETHEFPNADQILELAKSRMYDPKFSAIGEIGVDLYHDASTRSQQ
CCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHCCEEEECCCCCHHH
NDVLRKFLQFSSEYKLPVVIHSRDAFADTYEALKEYKTKAFGVIHCFTYDYEAAKQFVDL
HHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHEEEEEEEECCHHHHHHHHHH
GYYISFSGIVTFKSATDIQEAAKKIPLESMLIETDAPFLSPMPHRGKRNDSSHLPFVLEK
CEEEEEEEEEEECCHHHHHHHHHHCCHHHHEEECCCCCCCCCCCCCCCCCCCCCCHHHHH
MFNLRTEPNAEVADRIYQNSIKFTERKAYHHA
HHCCCCCCCHHHHHHHHHHCCHHHHHHHCCCC
>Mature Secondary Structure
MLFMGYSTIDTHCHLDIIREQGQSIEETLEKSRKVGVDRLVQIGIDLPSSNEAVRISETY
CEEECCCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHCCCCCCCCCEEEEEECC
STNELQISYSIGCHPTETHEFPNADQILELAKSRMYDPKFSAIGEIGVDLYHDASTRSQQ
CCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHCCEEEECCCCCHHH
NDVLRKFLQFSSEYKLPVVIHSRDAFADTYEALKEYKTKAFGVIHCFTYDYEAAKQFVDL
HHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHEEEEEEEECCHHHHHHHHHH
GYYISFSGIVTFKSATDIQEAAKKIPLESMLIETDAPFLSPMPHRGKRNDSSHLPFVLEK
CEEEEEEEEEEECCHHHHHHHHHHCCHHHHEEECCCCCCCCCCCCCCCCCCCCCCHHHHH
MFNLRTEPNAEVADRIYQNSIKFTERKAYHHA
HHCCCCCCCHHHHHHHHHHCCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]