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The map label for this gene is yrbE [H]

Identifier: 183222721

GI number: 183222721

Start: 3495948

End: 3496910

Strand: Reverse

Name: yrbE [H]

Synonym: LEPBI_I3377

Alternate gene names: 183222721

Gene position: 3496910-3495948 (Counterclockwise)

Preceding gene: 183222722

Following gene: 183222720

Centisome position: 97.15

GC content: 38.11

Gene sequence:

>963_bases
ATGGAGAAAAAAGTCCGACTCGGAGTCATTGGTACAGGCCATATGGGCCAGTACCACGTAAACGTTGCCAAACAATTAAC
TGATGCTGAACTCATCGGGATATTTGATGCCAGTGCAGAACGTGCCACCCAAATTGCTGAGAAACATAAAACAAAAGCAT
TTGGTACGATTGAAGATTTATTAAAGGAAACTGATGCAATCATCATTGCGGCACCTACTTTTTTACATCACAAGATCGCC
AAACAGGCGCTCACTGAAAAGAAACATGTTTTGGTAGAAAAACCAATCTCTCAAACGGTGGAAGAAGCCAAAGAACTTGT
AAACTTGGCAAAACAAAACAACTTGATATTACAAGTGGGCCATGTGGAACGATTCAATGGTGCTGTTTTGGAACTCGGTA
AAATTGCCGAACATCCAATTCTCATCGAATCCAGAAGAATTGCTCCTTATAATAGTCGTATCACTGATGTTGGTGTTGTT
CTCGATATGATGATTCATGATATCGACATCGTACTCAACTTAGTGAAGTCTGAAGTGACAGAAGTAAAGGCAGTTGGATC
TTCCATTGTGTCCAATCATGAAGATGTAGCGACTGTTGTTCTGAAATTTGCAAATGGATGTGTTGCTTCTTTAAATGCTT
CACGCTCCTCCCAAGCAAAAATACGAACACTCAATATTTCACAAAAAGATTCTTACGTATTTTTAGATTTCACCAACCAA
GAGATTGAATTGCATAGACAAGCAAGTTCAACAACTCAATTGGGAAGTGGAGAAATCAAATACAGGCAAGAATCCATTGT
GGAAAAAATCTTTGTTCACAAAGACAACCCTCTCAAACAAGAACATGAACACTTTGTAAAATGTATCAAAGGCGAATCTG
AACCAATGGTGAAAGGTGACTCTGATATCAAAACATTAGAAGTGGCATATAAAATTTTAGAAGAAATACACGGCAAAAAA
TAA

Upstream 100 bases:

>100_bases
ATTAATGGAAGAATTTGCCCGTGAGTCTGGCGAAAAGGTCGGCAGCGGGGGAAAATCGAAGTTGTTTTTCCGCTAATCCT
TTTAAATATTGAGAGCATCT

Downstream 100 bases:

>100_bases
TGACAGAAAATCCTGATTCAACTCGTGGGAAGTTACTGATTTCCAATTCTAGTGTGATTCAGGATTTTTTTCATAAATCC
GTTGTCCTTATGGTTGATCA

Product: oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MEKKVRLGVIGTGHMGQYHVNVAKQLTDAELIGIFDASAERATQIAEKHKTKAFGTIEDLLKETDAIIIAAPTFLHHKIA
KQALTEKKHVLVEKPISQTVEEAKELVNLAKQNNLILQVGHVERFNGAVLELGKIAEHPILIESRRIAPYNSRITDVGVV
LDMMIHDIDIVLNLVKSEVTEVKAVGSSIVSNHEDVATVVLKFANGCVASLNASRSSQAKIRTLNISQKDSYVFLDFTNQ
EIELHRQASSTTQLGSGEIKYRQESIVEKIFVHKDNPLKQEHEHFVKCIKGESEPMVKGDSDIKTLEVAYKILEEIHGKK

Sequences:

>Translated_320_residues
MEKKVRLGVIGTGHMGQYHVNVAKQLTDAELIGIFDASAERATQIAEKHKTKAFGTIEDLLKETDAIIIAAPTFLHHKIA
KQALTEKKHVLVEKPISQTVEEAKELVNLAKQNNLILQVGHVERFNGAVLELGKIAEHPILIESRRIAPYNSRITDVGVV
LDMMIHDIDIVLNLVKSEVTEVKAVGSSIVSNHEDVATVVLKFANGCVASLNASRSSQAKIRTLNISQKDSYVFLDFTNQ
EIELHRQASSTTQLGSGEIKYRQESIVEKIFVHKDNPLKQEHEHFVKCIKGESEPMVKGDSDIKTLEVAYKILEEIHGKK
>Mature_320_residues
MEKKVRLGVIGTGHMGQYHVNVAKQLTDAELIGIFDASAERATQIAEKHKTKAFGTIEDLLKETDAIIIAAPTFLHHKIA
KQALTEKKHVLVEKPISQTVEEAKELVNLAKQNNLILQVGHVERFNGAVLELGKIAEHPILIESRRIAPYNSRITDVGVV
LDMMIHDIDIVLNLVKSEVTEVKAVGSSIVSNHEDVATVVLKFANGCVASLNASRSSQAKIRTLNISQKDSYVFLDFTNQ
EIELHRQASSTTQLGSGEIKYRQESIVEKIFVHKDNPLKQEHEHFVKCIKGESEPMVKGDSDIKTLEVAYKILEEIHGKK

Specific function: Unknown

COG id: COG0673

COG function: function code R; Predicted dehydrogenases and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family [H]

Homologues:

Organism=Escherichia coli, GI87082405, Length=354, Percent_Identity=21.7514124293785, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787307, Length=178, Percent_Identity=28.0898876404494, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104 [H]

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 35589; Mature: 35589

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKKVRLGVIGTGHMGQYHVNVAKQLTDAELIGIFDASAERATQIAEKHKTKAFGTIEDL
CCCCEEEEEEECCCCCEEEHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
LKETDAIIIAAPTFLHHKIAKQALTEKKHVLVEKPISQTVEEAKELVNLAKQNNLILQVG
HHHCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCEEEEEC
HVERFNGAVLELGKIAEHPILIESRRIAPYNSRITDVGVVLDMMIHDIDIVLNLVKSEVT
CCCHHCCHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVKAVGSSIVSNHEDVATVVLKFANGCVASLNASRSSQAKIRTLNISQKDSYVFLDFTNQ
HHHHHHHHHHCCCHHHHHHHHHHHCCHHEECCCCCCCCCEEEEEECCCCCCEEEEEECCC
EIELHRQASSTTQLGSGEIKYRQESIVEKIFVHKDNPLKQEHEHFVKCIKGESEPMVKGD
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCC
SDIKTLEVAYKILEEIHGKK
CCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MEKKVRLGVIGTGHMGQYHVNVAKQLTDAELIGIFDASAERATQIAEKHKTKAFGTIEDL
CCCCEEEEEEECCCCCEEEHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
LKETDAIIIAAPTFLHHKIAKQALTEKKHVLVEKPISQTVEEAKELVNLAKQNNLILQVG
HHHCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCEEEEEC
HVERFNGAVLELGKIAEHPILIESRRIAPYNSRITDVGVVLDMMIHDIDIVLNLVKSEVT
CCCHHCCHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVKAVGSSIVSNHEDVATVVLKFANGCVASLNASRSSQAKIRTLNISQKDSYVFLDFTNQ
HHHHHHHHHHCCCHHHHHHHHHHHCCHHEECCCCCCCCCEEEEEECCCCCCEEEEEECCC
EIELHRQASSTTQLGSGEIKYRQESIVEKIFVHKDNPLKQEHEHFVKCIKGESEPMVKGD
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCC
SDIKTLEVAYKILEEIHGKK
CCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 9025289 [H]