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The map label for this gene is murB [H]

Identifier: 183222711

GI number: 183222711

Start: 3480268

End: 3481350

Strand: Reverse

Name: murB [H]

Synonym: LEPBI_I3367

Alternate gene names: 183222711

Gene position: 3481350-3480268 (Counterclockwise)

Preceding gene: 183222713

Following gene: 183222710

Centisome position: 96.71

GC content: 37.86

Gene sequence:

>1083_bases
ATGTTGGTCCAAAAGAATATCCCATTGGCTCCGTTGACTACATTTCGATTAGGTGGCCAAGCTAAGTATTTTATATCGAT
CAAAACAACAGAAGATCTAAAAGATGCACTTACCTTCTGCCAAAAGAATCAACTTCCTTATGTCATTTTAGGTGGTGGTT
CAAATACTATTTTTCGAGATCATGGATTTTATGGTGCCATTTTTTTAATCCAAATTCCCGGGATCAGATGTTTGGATGCA
AACGAATCAGAAGTTCTGTATGAAGTAGGTGCAGGTGTTGTTTGGGATCAATTTGTAGAATATGTCGTTAAACAAGGATT
AAGTGGTGTTGAGTGTCTGTCAGGTATTCCAGGATCTGTAGGCGCCTCACCAATCCAAAACATTGGTGCCTATGGCCAAG
AAGTTAAAGATTCAATTATAAGTGTTCAATGTATCGATGAAAATGGAAATCCGAAGACTATTTCTAATGAAGAATCTAAG
TTTACTTACCGAAATAGTGAATTCAAATCTGGAAAGTTTCGAAATTACATCATTACATCGGTCAGATTTAAACTATCGAA
AGAATTGGAGCCTTGTGTAATTTACCCGGAAGTCAAAAAACAATGGGAATTATTCCTTTCAGAGAGTAAAGAAAATCAAT
ATGAGGCCGAAGATCGATTTTTAAAACTCGAATCCCTGCGAAACTTGATAATCAATTTACGAAAGAAAAAATCAATGGTT
GTCGATGAATCTGATCCTAATACCCGATCGGCGGGATCTTTTTTTACAAACCCTATTATTTCAATATCTGATGCGGAAAA
ATTTTTAATCCAGGCAAAAAAATTAGGGCATTCGGATCCACCGATGTTCGATGACCATACTGGTGCGAAAAAACTTTCGG
CAGCTTGGCTCATAGAACACTCCGGTATCAAAAAAGGGGACGTGTTTCCGGGTGGAGTCGGTATCTCGACCAACCACTGT
TTGGGTCTAATCAATATAAATGGGACAACTTCTGCATTATTGGAAATGGCAGAATCGATCCAAAATCGAGTCTTTGATAC
TTTTTCAATCCGTTTGGAGATGGAACCAGTACTCAGACCCTAA

Upstream 100 bases:

>100_bases
CATGTGCTACAGCCGGAATATTCGTAAACTTTCAGTTTGGATCGACTCATAAGACAGATTTTCTTACTTACTATTTTTGC
GGAAACTTTTTATTGGAACT

Downstream 100 bases:

>100_bases
AAAAGATTTGGTAATTGTCGATAGTTGCAGAAGGATGGGGAAGGAATGAACTCAAAAGTTAAAAAATACCTAGTACTTTC
AGGATTAGGTGCCGCATTAC

Product: UDP-N- acetylmuramate dehydrogenase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase [H]

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MLVQKNIPLAPLTTFRLGGQAKYFISIKTTEDLKDALTFCQKNQLPYVILGGGSNTIFRDHGFYGAIFLIQIPGIRCLDA
NESEVLYEVGAGVVWDQFVEYVVKQGLSGVECLSGIPGSVGASPIQNIGAYGQEVKDSIISVQCIDENGNPKTISNEESK
FTYRNSEFKSGKFRNYIITSVRFKLSKELEPCVIYPEVKKQWELFLSESKENQYEAEDRFLKLESLRNLIINLRKKKSMV
VDESDPNTRSAGSFFTNPIISISDAEKFLIQAKKLGHSDPPMFDDHTGAKKLSAAWLIEHSGIKKGDVFPGGVGISTNHC
LGLININGTTSALLEMAESIQNRVFDTFSIRLEMEPVLRP

Sequences:

>Translated_360_residues
MLVQKNIPLAPLTTFRLGGQAKYFISIKTTEDLKDALTFCQKNQLPYVILGGGSNTIFRDHGFYGAIFLIQIPGIRCLDA
NESEVLYEVGAGVVWDQFVEYVVKQGLSGVECLSGIPGSVGASPIQNIGAYGQEVKDSIISVQCIDENGNPKTISNEESK
FTYRNSEFKSGKFRNYIITSVRFKLSKELEPCVIYPEVKKQWELFLSESKENQYEAEDRFLKLESLRNLIINLRKKKSMV
VDESDPNTRSAGSFFTNPIISISDAEKFLIQAKKLGHSDPPMFDDHTGAKKLSAAWLIEHSGIKKGDVFPGGVGISTNHC
LGLININGTTSALLEMAESIQNRVFDTFSIRLEMEPVLRP
>Mature_360_residues
MLVQKNIPLAPLTTFRLGGQAKYFISIKTTEDLKDALTFCQKNQLPYVILGGGSNTIFRDHGFYGAIFLIQIPGIRCLDA
NESEVLYEVGAGVVWDQFVEYVVKQGLSGVECLSGIPGSVGASPIQNIGAYGQEVKDSIISVQCIDENGNPKTISNEESK
FTYRNSEFKSGKFRNYIITSVRFKLSKELEPCVIYPEVKKQWELFLSESKENQYEAEDRFLKLESLRNLIINLRKKKSMV
VDESDPNTRSAGSFFTNPIISISDAEKFLIQAKKLGHSDPPMFDDHTGAKKLSAAWLIEHSGIKKGDVFPGGVGISTNHC
LGLININGTTSALLEMAESIQNRVFDTFSIRLEMEPVLRP

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Escherichia coli, GI1790407, Length=353, Percent_Identity=29.1784702549575, Blast_Score=152, Evalue=3e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 40050; Mature: 40050

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVQKNIPLAPLTTFRLGGQAKYFISIKTTEDLKDALTFCQKNQLPYVILGGGSNTIFRD
CCCCCCCCCCCCEEEEECCCEEEEEEEECHHHHHHHHHHHHCCCCCEEEEECCCCCEEEC
HGFYGAIFLIQIPGIRCLDANESEVLYEVGAGVVWDQFVEYVVKQGLSGVECLSGIPGSV
CCCEEEEEEEEECCEEEECCCCCCEEEECCCCHHHHHHHHHHHHCCCCHHHHHCCCCCCC
GASPIQNIGAYGQEVKDSIISVQCIDENGNPKTISNEESKFTYRNSEFKSGKFRNYIITS
CCCHHHHHHHHHHHHHHCEEEEEEECCCCCCCCCCCCCCCEEECCCCCCCCCCCEEEEEE
VRFKLSKELEPCVIYPEVKKQWELFLSESKENQYEAEDRFLKLESLRNLIINLRKKKSMV
EEEEHHCCCCCEEEEHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEE
VDESDPNTRSAGSFFTNPIISISDAEKFLIQAKKLGHSDPPMFDDHTGAKKLSAAWLIEH
EECCCCCCCCCCCHHCCCCEEECCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHEEEEEC
SGIKKGDVFPGGVGISTNHCLGLININGTTSALLEMAESIQNRVFDTFSIRLEMEPVLRP
CCCCCCCCCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHEEEEEEEEEECCCCCC
>Mature Secondary Structure
MLVQKNIPLAPLTTFRLGGQAKYFISIKTTEDLKDALTFCQKNQLPYVILGGGSNTIFRD
CCCCCCCCCCCCEEEEECCCEEEEEEEECHHHHHHHHHHHHCCCCCEEEEECCCCCEEEC
HGFYGAIFLIQIPGIRCLDANESEVLYEVGAGVVWDQFVEYVVKQGLSGVECLSGIPGSV
CCCEEEEEEEEECCEEEECCCCCCEEEECCCCHHHHHHHHHHHHCCCCHHHHHCCCCCCC
GASPIQNIGAYGQEVKDSIISVQCIDENGNPKTISNEESKFTYRNSEFKSGKFRNYIITS
CCCHHHHHHHHHHHHHHCEEEEEEECCCCCCCCCCCCCCCEEECCCCCCCCCCCEEEEEE
VRFKLSKELEPCVIYPEVKKQWELFLSESKENQYEAEDRFLKLESLRNLIINLRKKKSMV
EEEEHHCCCCCEEEEHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEE
VDESDPNTRSAGSFFTNPIISISDAEKFLIQAKKLGHSDPPMFDDHTGAKKLSAAWLIEH
EECCCCCCCCCCCHHCCCCEEECCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHEEEEEC
SGIKKGDVFPGGVGISTNHCLGLININGTTSALLEMAESIQNRVFDTFSIRLEMEPVLRP
CCCCCCCCCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHEEEEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA