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The map label for this gene is suhB [H]

Identifier: 183222611

GI number: 183222611

Start: 3380108

End: 3380923

Strand: Reverse

Name: suhB [H]

Synonym: LEPBI_I3266

Alternate gene names: 183222611

Gene position: 3380923-3380108 (Counterclockwise)

Preceding gene: 183222612

Following gene: 183222606

Centisome position: 93.92

GC content: 38.36

Gene sequence:

>816_bases
TTGATGCTTTCTGAATTACATGATAGGTCTTATCATTTTTTAAACTTTTTACCAAATGTCGCAAACTTCCTCGTTGAAAA
ACACAAAGAATCCGACTTAAAAGTTGATGAAAAAAGTTTATACAACTTAGTCACAGAAGCTGATCTTAAAGCAGAATCGA
TGATTCTGGAAGAAATTCAAAAAAATTTCCCCTCGGATGGAATCCTCGCTGAAGAACGTGGGGCCATTCCTGGAACATCT
GGTTATACTTGGGTGATAGATCCTTTGGATGGCACAACCAATTATACACATGGATTGCCATTGTATGGAATTTCAGTGGG
AGTTGTGGAAACAGAATCGATGGCACCTGTCATCGGAATGGTTTTTTTTCCTGAACTGGGTACCTATTACCATGCAATCA
AAGGACAAGGTGCCTTCCGAGAGAAAAAACAAATCCAAGTATCTCAAACGAAAGCGATGAAAGATTCCCTTTTTGTCACT
GGGTTTCCTTATGATCGAAACTTGTCTTTGGATACATTAATGCAGTATTATAAATCGATTTTACAAAAATCACGTGGGAT
TCGTCGTACTGGTGCCGCGACGTTAGACTTATGTTGGTTAGCCGAAGGAAAATTTGAAGGTTATTACGAATTAGGTTTGA
AACCTTGGGATATGGCGGCAGCTGGTCTCATTGTGATGGAAGCAAAAGGAAAATTAACTTCAATGGATGGAAACGATTTT
TCGATTATGATTCCAAGTTTACTTGCAAGCAACGGTCAAGTACATGACTACTTACTTGCGGAATTTGAAGGTCAAATTAA
CCGAGTAGCATATTAA

Upstream 100 bases:

>100_bases
AAACTACGGAACAAGTGCGAAATAAATTAAAAGCTGACGAAACCCTAAATTTAGATGTTGAGATCACTGCGATGAAAAAA
AACATCGAATTTGGTGGGTA

Downstream 100 bases:

>100_bases
CCATCTGATTCAGTTTGGTTTTGATCACAGGTTTCGTAAAATTCGCGAGGACGTACTTTCTTCCATTTTTACCCAATTGA
TTTGCGATAGATTGGTGATC

Product: inositol-1-monophosphatase

Products: NA

Alternate protein names: I-1-Pase; IMPase; Inositol-1-phosphatase [H]

Number of amino acids: Translated: 271; Mature: 271

Protein sequence:

>271_residues
MMLSELHDRSYHFLNFLPNVANFLVEKHKESDLKVDEKSLYNLVTEADLKAESMILEEIQKNFPSDGILAEERGAIPGTS
GYTWVIDPLDGTTNYTHGLPLYGISVGVVETESMAPVIGMVFFPELGTYYHAIKGQGAFREKKQIQVSQTKAMKDSLFVT
GFPYDRNLSLDTLMQYYKSILQKSRGIRRTGAATLDLCWLAEGKFEGYYELGLKPWDMAAAGLIVMEAKGKLTSMDGNDF
SIMIPSLLASNGQVHDYLLAEFEGQINRVAY

Sequences:

>Translated_271_residues
MMLSELHDRSYHFLNFLPNVANFLVEKHKESDLKVDEKSLYNLVTEADLKAESMILEEIQKNFPSDGILAEERGAIPGTS
GYTWVIDPLDGTTNYTHGLPLYGISVGVVETESMAPVIGMVFFPELGTYYHAIKGQGAFREKKQIQVSQTKAMKDSLFVT
GFPYDRNLSLDTLMQYYKSILQKSRGIRRTGAATLDLCWLAEGKFEGYYELGLKPWDMAAAGLIVMEAKGKLTSMDGNDF
SIMIPSLLASNGQVHDYLLAEFEGQINRVAY
>Mature_271_residues
MMLSELHDRSYHFLNFLPNVANFLVEKHKESDLKVDEKSLYNLVTEADLKAESMILEEIQKNFPSDGILAEERGAIPGTS
GYTWVIDPLDGTTNYTHGLPLYGISVGVVETESMAPVIGMVFFPELGTYYHAIKGQGAFREKKQIQVSQTKAMKDSLFVT
GFPYDRNLSLDTLMQYYKSILQKSRGIRRTGAATLDLCWLAEGKFEGYYELGLKPWDMAAAGLIVMEAKGKLTSMDGNDF
SIMIPSLLASNGQVHDYLLAEFEGQINRVAY

Specific function: Unknown

COG id: COG0483

COG function: function code G; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Homo sapiens, GI5031789, Length=224, Percent_Identity=34.8214285714286, Blast_Score=136, Evalue=2e-32,
Organism=Homo sapiens, GI221625487, Length=224, Percent_Identity=34.8214285714286, Blast_Score=135, Evalue=3e-32,
Organism=Homo sapiens, GI7657236, Length=254, Percent_Identity=30.7086614173228, Blast_Score=127, Evalue=1e-29,
Organism=Homo sapiens, GI221625507, Length=117, Percent_Identity=36.7521367521368, Blast_Score=79, Evalue=4e-15,
Organism=Escherichia coli, GI1788882, Length=251, Percent_Identity=31.0756972111554, Blast_Score=144, Evalue=6e-36,
Organism=Caenorhabditis elegans, GI193202572, Length=262, Percent_Identity=30.1526717557252, Blast_Score=120, Evalue=7e-28,
Organism=Caenorhabditis elegans, GI193202570, Length=265, Percent_Identity=29.4339622641509, Blast_Score=114, Evalue=4e-26,
Organism=Saccharomyces cerevisiae, GI6320493, Length=244, Percent_Identity=32.3770491803279, Blast_Score=126, Evalue=4e-30,
Organism=Saccharomyces cerevisiae, GI6321836, Length=245, Percent_Identity=26.1224489795918, Blast_Score=91, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24664922, Length=218, Percent_Identity=31.1926605504587, Blast_Score=124, Evalue=9e-29,
Organism=Drosophila melanogaster, GI24664926, Length=229, Percent_Identity=32.3144104803493, Blast_Score=123, Evalue=1e-28,
Organism=Drosophila melanogaster, GI21357329, Length=242, Percent_Identity=29.3388429752066, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI21357957, Length=253, Percent_Identity=30.0395256916996, Blast_Score=105, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24664918, Length=243, Percent_Identity=31.2757201646091, Blast_Score=103, Evalue=9e-23,
Organism=Drosophila melanogaster, GI21357303, Length=234, Percent_Identity=29.0598290598291, Blast_Score=103, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550
- InterPro:   IPR022337 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.25 [H]

Molecular weight: Translated: 30337; Mature: 30337

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS00629 IMP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMLSELHDRSYHFLNFLPNVANFLVEKHKESDLKVDEKSLYNLVTEADLKAESMILEEIQ
CCHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHH
KNFPSDGILAEERGAIPGTSGYTWVIDPLDGTTNYTHGLPLYGISVGVVETESMAPVIGM
HHCCCCCCEECCCCCCCCCCCCEEEEECCCCCCCCCCCCEEEEEEEEEEECCCCCHHHHH
VFFPELGTYYHAIKGQGAFREKKQIQVSQTKAMKDSLFVTGFPYDRNLSLDTLMQYYKSI
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCEEEEECCCCCCCCHHHHHHHHHHH
LQKSRGIRRTGAATLDLCWLAEGKFEGYYELGLKPWDMAAAGLIVMEAKGKLTSMDGNDF
HHHHCCCCCCCCCEEEEEEEECCCCCCEEECCCCCHHHHHCCEEEEECCCCEEECCCCCE
SIMIPSLLASNGQVHDYLLAEFEGQINRVAY
EEEECHHHCCCCCCHHHHHHHHCCCHHHCCC
>Mature Secondary Structure
MMLSELHDRSYHFLNFLPNVANFLVEKHKESDLKVDEKSLYNLVTEADLKAESMILEEIQ
CCHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHH
KNFPSDGILAEERGAIPGTSGYTWVIDPLDGTTNYTHGLPLYGISVGVVETESMAPVIGM
HHCCCCCCEECCCCCCCCCCCCEEEEECCCCCCCCCCCCEEEEEEEEEEECCCCCHHHHH
VFFPELGTYYHAIKGQGAFREKKQIQVSQTKAMKDSLFVTGFPYDRNLSLDTLMQYYKSI
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCEEEEECCCCCCCCHHHHHHHHHHH
LQKSRGIRRTGAATLDLCWLAEGKFEGYYELGLKPWDMAAAGLIVMEAKGKLTSMDGNDF
HHHHCCCCCCCCCEEEEEEEECCCCCCEEECCCCCHHHHHCCEEEEECCCCEEECCCCCE
SIMIPSLLASNGQVHDYLLAEFEGQINRVAY
EEEECHHHCCCCCCHHHHHHHHCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]