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The map label for this gene is czcB [H]

Identifier: 183222446

GI number: 183222446

Start: 3213187

End: 3214326

Strand: Direct

Name: czcB [H]

Synonym: LEPBI_I3100

Alternate gene names: 183222446

Gene position: 3213187-3214326 (Clockwise)

Preceding gene: 183222445

Following gene: 183222447

Centisome position: 89.26

GC content: 33.25

Gene sequence:

>1140_bases
ATGAAAAAAAATATCAAAATACTATTCTTATCCATATTACTTATTTTCATCTCATATTATTTTTGGCAATCACGTCAGAA
CAATCTCATTACTGAAGAACAACAAAATAATAAAGACACACTTCACCTAACAAATGAGCAGAAGAAAGAAATTCAAATTA
AAATTGAAACAGTAAGTTTATCGCCAATCCATACAAACATTGAACTGATTGGTGAAACTGAATCTGTCCCTGATGATATT
ATGGATGTTCCAGCAAGAATTTCAGGTAGAGTCACATCTGTATTTTTTGTAGAAGGAGATACCATTCAAAAAGGACAAAA
ATTAGCAATTATAGATTCACCAGAACTTGCGAAACTTCGATCTACCTATTTGGTTTCAAAATCAAAATATACTGCTGCAG
AACAAAATTTAACAAGAATTAACTCACTCGTAAAAATGAATTTGGCAGCAAAGCAGGAATTAATTGATGCCGAAGCAAAT
TTACGAGTGATTGAATCTGAAAAAAATTCTGCAGAGGAAAATTTGAGGGCCAATGGACTGGGGATTGATAACTCTTCCAC
TGGCCAGTATATAGTGTATGCCCCTAGATCTGGTTTAGCACTTTCTCGAAATGCTGTTCTAGGTTCGATTGTTTTAGGGA
ATCAAATTCTTACAACCATTGCAAACCTAACTAATCTTTGGTTCCAAGCCAAAATCTACGAAAATGATCTCAAATATTTG
ACAGAAGGAGTATCTGCTAAAGTCATATTAAATGCTTATCCCGATTTAGTATTTTTAGGAAAATTAGAACACATCGGAGA
AAAAGTTGATCTAGAGTCTAGGACAGTCCATGCTCGCGTTGTTTTTAAAAATACAAACCGTAAAGCAAAAATTGGTCTTT
TTGGAAAAGCTATCCTCAGTGTGAATGAAAGAATTGGAATTCAAATTCCTGAATCGTCAATTCAATCCTACCAAAATTCA
AAATTTGTTTTTTTAGAAACAAAGCCAGATGTATATCATTGGATCGAAGTCACTACAGGGTTTACCGAGAATCAAAAAAC
CGAAGTTTTGACTGGCCTTAAAGAAGGTGATAAAGTTGTAACAAAAGGATCATTTGAATTAAAATCGATTTTATTCAAAG
ATACCTTCGGTGGAGAATGA

Upstream 100 bases:

>100_bases
CAAAATTAAATTACTTAAATACAAAATCAGAGTACGAAGTATCACAAATTGAATTAATTCGTGTACTTGGATTACCTACA
GACATATTGGAAATACGACC

Downstream 100 bases:

>100_bases
AATGGAATTTTTAACAAAATTAGTCCATTTTTCACTTCAGAATCGACTTTTAATTTTAATATTTACAGTATTACTCGTAT
TTGGTGGATTTTATTCGTTA

Product: putative cation efflux system protein CzcB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MKKNIKILFLSILLIFISYYFWQSRQNNLITEEQQNNKDTLHLTNEQKKEIQIKIETVSLSPIHTNIELIGETESVPDDI
MDVPARISGRVTSVFFVEGDTIQKGQKLAIIDSPELAKLRSTYLVSKSKYTAAEQNLTRINSLVKMNLAAKQELIDAEAN
LRVIESEKNSAEENLRANGLGIDNSSTGQYIVYAPRSGLALSRNAVLGSIVLGNQILTTIANLTNLWFQAKIYENDLKYL
TEGVSAKVILNAYPDLVFLGKLEHIGEKVDLESRTVHARVVFKNTNRKAKIGLFGKAILSVNERIGIQIPESSIQSYQNS
KFVFLETKPDVYHWIEVTTGFTENQKTEVLTGLKEGDKVVTKGSFELKSILFKDTFGGE

Sequences:

>Translated_379_residues
MKKNIKILFLSILLIFISYYFWQSRQNNLITEEQQNNKDTLHLTNEQKKEIQIKIETVSLSPIHTNIELIGETESVPDDI
MDVPARISGRVTSVFFVEGDTIQKGQKLAIIDSPELAKLRSTYLVSKSKYTAAEQNLTRINSLVKMNLAAKQELIDAEAN
LRVIESEKNSAEENLRANGLGIDNSSTGQYIVYAPRSGLALSRNAVLGSIVLGNQILTTIANLTNLWFQAKIYENDLKYL
TEGVSAKVILNAYPDLVFLGKLEHIGEKVDLESRTVHARVVFKNTNRKAKIGLFGKAILSVNERIGIQIPESSIQSYQNS
KFVFLETKPDVYHWIEVTTGFTENQKTEVLTGLKEGDKVVTKGSFELKSILFKDTFGGE
>Mature_379_residues
MKKNIKILFLSILLIFISYYFWQSRQNNLITEEQQNNKDTLHLTNEQKKEIQIKIETVSLSPIHTNIELIGETESVPDDI
MDVPARISGRVTSVFFVEGDTIQKGQKLAIIDSPELAKLRSTYLVSKSKYTAAEQNLTRINSLVKMNLAAKQELIDAEAN
LRVIESEKNSAEENLRANGLGIDNSSTGQYIVYAPRSGLALSRNAVLGSIVLGNQILTTIANLTNLWFQAKIYENDLKYL
TEGVSAKVILNAYPDLVFLGKLEHIGEKVDLESRTVHARVVFKNTNRKAKIGLFGKAILSVNERIGIQIPESSIQSYQNS
KFVFLETKPDVYHWIEVTTGFTENQKTEVLTGLKEGDKVVTKGSFELKSILFKDTFGGE

Specific function: CzcA and CzcB together would act in zinc efflux nearly as effectively as the complete czc efflux system (CzcABC). The CzcB protein is thought to funnel zinc cations to the CzcA transport protein [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Attached To The Inner Membrane By A Lipid Anchor [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1789929, Length=348, Percent_Identity=25, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005695
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 42519; Mature: 42519

Theoretical pI: Translated: 7.82; Mature: 7.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKNIKILFLSILLIFISYYFWQSRQNNLITEEQQNNKDTLHLTNEQKKEIQIKIETVSL
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCEEEEEEEEEEEE
SPIHTNIELIGETESVPDDIMDVPARISGRVTSVFFVEGDTIQKGQKLAIIDSPELAKLR
CCEECCEEEEECCCCCCHHHHHCCCCCCCCEEEEEEEECCCCCCCCEEEEECCCCHHHHH
STYLVSKSKYTAAEQNLTRINSLVKMNLAAKQELIDAEANLRVIESEKNSAEENLRANGL
HHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHCCCCCCC
GIDNSSTGQYIVYAPRSGLALSRNAVLGSIVLGNQILTTIANLTNLWFQAKIYENDLKYL
CCCCCCCCCEEEEECCCCCEEECCCEEEEEEECHHHHHHHHHHHHHEEEEEEEHHHHHHH
TEGVSAKVILNAYPDLVFLGKLEHIGEKVDLESRTVHARVVFKNTNRKAKIGLFGKAILS
HCCCCEEEEEECCCCEEEECCHHHCCCCCCCCCCEEEEEEEEECCCCEEEEEEHHHHHHC
VNERIGIQIPESSIQSYQNSKFVFLETKPDVYHWIEVTTGFTENQKTEVLTGLKEGDKVV
CCCCCEEEECHHHHHHHCCCEEEEEECCCCEEEEEEEECCCCCCCCHHHHHCCCCCCEEE
TKGSFELKSILFKDTFGGE
ECCCHHHHHEEEECCCCCC
>Mature Secondary Structure
MKKNIKILFLSILLIFISYYFWQSRQNNLITEEQQNNKDTLHLTNEQKKEIQIKIETVSL
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCEEEEEEEEEEEE
SPIHTNIELIGETESVPDDIMDVPARISGRVTSVFFVEGDTIQKGQKLAIIDSPELAKLR
CCEECCEEEEECCCCCCHHHHHCCCCCCCCEEEEEEEECCCCCCCCEEEEECCCCHHHHH
STYLVSKSKYTAAEQNLTRINSLVKMNLAAKQELIDAEANLRVIESEKNSAEENLRANGL
HHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHCCCCCCC
GIDNSSTGQYIVYAPRSGLALSRNAVLGSIVLGNQILTTIANLTNLWFQAKIYENDLKYL
CCCCCCCCCEEEEECCCCCEEECCCEEEEEEECHHHHHHHHHHHHHEEEEEEEHHHHHHH
TEGVSAKVILNAYPDLVFLGKLEHIGEKVDLESRTVHARVVFKNTNRKAKIGLFGKAILS
HCCCCEEEEEECCCCEEEECCHHHCCCCCCCCCCEEEEEEEEECCCCEEEEEEHHHHHHC
VNERIGIQIPESSIQSYQNSKFVFLETKPDVYHWIEVTTGFTENQKTEVLTGLKEGDKVV
CCCCCEEEECHHHHHHHCCCEEEEEECCCCEEEEEEEECCCCCCCCHHHHHCCCCCCEEE
TKGSFELKSILFKDTFGGE
ECCCHHHHHEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8829543 [H]